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  1. 4121
    “…LINCs were optogenetically activated for on-demand seizure intervention in the intrahippocampal kainate (KA) mouse model of chronic TLE. Unexpectedly, LINC activation at 1 month post-KA did not substantially reduce seizure duration in either male or female mice. …”
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    LINCs Are Vulnerable to Epileptic Insult and Fail to Provide Seizure Control via On-Demand Activation
  2. 4122
    “…These analyses highlighted major genetic differences for Tibetan A. laboriosa as well as the Hainan Island A. dorsata. The demographic history of most giant honeybee populations has mirrored glacial cycles. …”
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    Population Structure, Demographic History, and Adaptation of Giant Honeybees in China Revealed by Population Genomic Data
  3. 4123
    “…The GMB composition of within group weight gainers versus non-weight gainer will also be assessed in a subgroup of subjects using LEfSe. …”
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    T192. THE GUT MICROBIOME IN SCHIZOPHRENIA AND ANTIPSYCHOTIC INDUCED METABOLIC DYSFUNCTION
  4. 4124
    “…(S)-GNA is well tolerated in the seed regions of antisense and sense strands of a GalNAc-conjugated siRNA in vitro. The siRNAs containing a GNA base pair in the seed region had in vivo potency when subcutaneously injected into mice. …”
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    Acyclic (S)-glycol nucleic acid (S-GNA) modification of siRNAs improves the safety of RNAi therapeutics while maintaining potency
  5. 4125
    “…We first established the metabolic glycan labelling (MGL) strategy with N‐azidoacetylgalactosamine (GalNAz) in rice seedlings, which enabled incorporation of azides as a bioorthogonal handle into O‐GlcNAc. …”
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    Chemoproteomic profiling of O‐GlcNAcylated proteins and identification of O‐GlcNAc transferases in rice
  6. 4126
    “…In this experiment, CcMYB24 was cloned from Hainan Huangdenglong pepper, a hot aromatic pepper variety popular in the world for processing, and its function was confirmed by tissue expression characteristics, heterologous transformation in Arabidopsis thaliana, and VIGS technology. …”
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    MYB24 Negatively Regulates the Biosynthesis of Lignin and Capsaicin by Affecting the Expression of Key Genes in the Phenylpropanoid Metabolism Pathway in Capsicum chinense
  7. 4127
    “…METHODS: This study was performed in two tertiary hospitals in Hainan, China between December 2020 and July 2021, 123 patients were included. …”
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    Development and evaluation of a rehabilitation training compliance scale for patients with urinary incontinence
  8. 4128
    “…Seven hundred and eighty‐four participants with hypertension and 645 participants without hypertension were included from five villages in Tibetan Autonomous Region of Gannan during 2013–2014. The assessment of salt sensitivity (SS) and non‐salt sensitivity (NSS) was performed according to mean arterial pressure (MAP) changes by the modified Sullivan's acute oral saline load and diuresis shrinkage test (MSAOSL‐DST). …”
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    Association between salt sensitivity of blood pressure and the risk of hypertension in a Chinese Tibetan population
  9. 4129
    “…Xylocopa caerulea and Xylocopa auripennis are important pollinators of wild plants on Hainan Island. Whether they have host-specific bacteria in their guts similar to eusocial bees remains unknown. …”
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    Xylocopa caerulea and Xylocopa auripennis harbor a homologous gut microbiome related to that of eusocial bees
  10. 4130
    “…Their ability to influx Ca(2+) into cells, unlike mature AMPA or kainate receptors, implicates them in a variety of processes ranging from synaptic plasticity to cell death. …”
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    Visualizing the triheteromeric N-methyl-D-aspartate receptor subunit composition
  11. 4131
    “…METHODS: A retrospective cohort study was conducted on the clinical data on consecutive patients with cirrhosis and splenomegaly treated at Hainan General Hospital, China, from January 2000 to December 2020. …”
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    Coagulation Dysfunction in Patients with Liver Cirrhosis and Splenomegaly and Its Countermeasures: A Retrospective Study of 1522 Patients
  12. 4132
    “…METHODS: This retrospective observational study reviewed the clinical data of 89 patients diagnosed with T2DM in the Department of Acupuncture and Massage, Hainan Medical University from January 2021 to June 2022. …”
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    Gegen Qinlian Decoction combined with Metformin for the treatment of patients with Type-2 Diabetes Mellitus: A retrospective observational study
  13. 4133
    “…Further analysis showed that the Siaα2-6Gal/N-acetylgalactosamine (GalNAc) structures recognized by SNA were significantly increased. …”
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    Alterations in mitochondrial protein glycosylation in myocardial ischaemia reperfusion injury
  14. 4134
    “…Wistar male rats were injected bilaterally with viral vectors and 3 weeks later acute seizures were induced by a subcutaneous injection of kainate. The latency until 1(st) motor seizure, time spent in motor seizure and latency to status epilepticus were measured to evaluate the seizure-suppressing efficacy of these vectors compared to an empty cassette control vector. …”
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    Combinatorial gene therapy for epilepsy: Gene sequence positioning and AAV serotype influence expression and inhibitory effect on seizures
  15. 4135
    “…A case control study was conducted at Hainan Women and Children’s Medical Center from January 1 to December 31, 2021. …”
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    The determinants of neonatal asphyxia in the tropical province of China: A case-control study
  16. 4136
    por He, Mengqi, Tang, Sanyi, Xiao, Yanni
    Publicado 2023
    “…We show that the proposed algorithm can fit the multi-source epidemic data in Xi’an, Guangzhou and Yangzhou cities well, and moreover reconstruct the epidemic development trend in Hainan and Xinjiang with incomplete reported data. …”
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    Combining the dynamic model and deep neural networks to identify the intensity of interventions during COVID-19 pandemic
  17. 4137
    “…The final oligosaccharide sequence of AgA consists of Gal-GlcNAc-Gal (GalNAc)-Fuc. AgB contains Gal-GlcNAc-Gal (Gal)-Fuc. …”
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    Mechanisms of Formation of Antibodies against Blood Group Antigens That Do Not Exist in the Body
  18. 4138
    “…METHODS/DESIGN: For this prospective cohort study, we recruited 756 participants from the community in Sanya City, Hainan Province, China. In addition to the completed baseline survey, a follow-up survey will be conducted during the periods of October–December and March–April for the next 3 years of MBEPs from northern China who spend the winter in Sanya. …”
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    Sanya climatic-treatment cohort profile: objectives, design, and baseline characteristics
  19. 4139
    “…METHODS: As part of the China Hainan Centenarian Cohort Study, a total of 1565 individuals over 80 years old were included. …”
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    Homocysteine Combined with Apolipoprotein B as Serum Biomarkers for Predicting Carotid Atherosclerosis in the Oldest-Old
  20. 4140
    “…Gene expression analyses of adipose tissue and hypothalamus from mice with low and high weight gain, by microarray and qRT-PCR, showed major changes in the expression of genes of Wnt signaling and tissue re-modeling in adipose tissue. …”
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    Changes in Gene Expression Foreshadow Diet-Induced Obesity in Genetically Identical Mice
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