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4341por Tang, Xinyu, Tena, Jennyfer, Di Lucente, Jacopo, Maezawa, Izumi, Harvey, Danielle J., Jin, Lee-Way, Lebrilla, Carlito B., Zivkovic, Angela M.“…Isozyme-specific changes were observed in expression of the polypeptide N-acetylgalactosaminyltransferase (GALNT) family and the alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (ST6GALNAC) family of enzymes. Several glycolipid-specific genes (UGT8, PIGM) were upregulated. …”
Publicado 2023
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4342“…Blepharoglossum is a rare orchid genus of the Malaxidinae primarily distributed in tropical Pacific islands, with several species occurring in the Taiwan and Hainan Islands of China. Currently, the monophyletic status of Blepharoglossum has been challenged, and the phylogenetic relationships among its allied groups have remained unresolved with traditional DNA markers. …”
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4343por Erger, Florian, Aryal, Rajindra P., Reusch, Björn, Matsumoto, Yasuyuki, Meyer, Robert, Zeng, Junwei, Knopp, Cordula, Noel, Maxence, Muerner, Lukas, Wenzel, Andrea, Kohl, Stefan, Tschernoster, Nikolai, Rappl, Gunter, Rouvet, Isabelle, Schröder-Braunstein, Jutta, Seibert, Felix S., Thiele, Holger, Häusler, Martin G., Weber, Lutz T., Büttner-Herold, Maike, Elbracht, Miriam, Cummings, Sandra F., Altmüller, Janine, Habbig, Sandra, Cummings, Richard D., Beck, Bodo B.“…Although A20D-Cosmc is functional, its decreased expression, though in a cell or tissue-specific manner, causes a large reduction of T-synthase protein and activity, which accordingly leads to expression of varied amounts of pathological Tn-antigen (GalNAcα1-O-Ser/Thr/Tyr) on multiple glycoproteins. …”
Publicado 2023
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4344por Roshini, Janardhanaachari, Patro, L. Ponoop Prasad, Sundaresan, Sruthi, Rathinavelan, Thenmalarchelvi“…A total of 64 (out of 237 K-locus(KL) types) known K-antigen sugar repeating structures are discussed here and are classified into seven groups based on their initial sugars, QuiNAc4NAc, GalNAc, GlcNAc, Gal, QuiNAc/FucNAc, FucNAc, and GlcNAc along with Leg5Ac7Ac/Leg5Ac7R. …”
Publicado 2023
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4345“…Blocking the primary rod pathway with L-AP4 and/or strychnine reduced rod-driven optogenetic currents in OFF RGCs by ~1/3. Blocking kainate receptors of OFF cone bipolar cells suppressed both rod- and cone-driven optogenetic currents in OFF RGCs. …”
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4346por Wu, Wentao, Li, Gaoyu, Zhou, Weijuan, Wang, Enbo, Zhao, Xia, Song, Xiqiang, Zhao, Ying“…Numerous plants of medicinal value grow on Hainan Island (China). Given the lack of knowledge on the phytochemical and pharmacological properties of Michelia shiluensis Chun and Y. …”
Publicado 2023
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4347por Hof, Wouter van't, Malik, Abha, Vijayakumar, S., Qiao, Jizeng, van Adelsberg, Janet, Al-Awqati, Qais“…The ganglioside GM(1) (Gal 1β1, 3GalNAcβ1, 4Gal-NeuAcα2, 3Galβ1, 4Glc ceramide) was confined to the apical membrane as visualized by confocal microscopy after addition of fluorescent cholera toxin to filter grown cells. …”
Publicado 1997
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4348Publicado 1994“…Analysis of the gonococcal mutants indicates that four of these genes are the glycosyl transferases that add GalNAc beta 1-->3Gal beta 1-->4GlcNAc beta 1-->3 Gal beta 1--4 to the substrate Glc beta 1-->4Hep--R of the inner core region. …”
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4349“…We examined the receptors simultaneously using non-quantitative single-cell reverse transcriptase polymerase chain reaction for GluR1-R4 (α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors), GluR5-R7, and KA1 and 2 (kainate receptors), δ1 and δ2 subunits, and the N-methyl-D-aspartate (NMDA) receptor subunits NR1, 2a-d, and 3a. …”
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4350“…METHODS: In depth interviews were conducted with 23 maintainers and four slight gainers in Sweden. The interviews were transcribed and an analysis of weight maintenance was performed using Grounded Theory. …”
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4351“…By using these markers, we found that the intergroup gene diversity of J. curcas was greater than the intragroup diversity, and that the domestication of the species probably occurred partly in America and partly in Hainan, China.…”
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4352“…The target pentasaccharide, an α-GalNAc substituted lacto-N-neotetraose structure, comprises a phosphoethanolamine motif and a spacer aglycon. …”
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4353por Semchenko, Evgeny A, Day, Christopher J, Wilson, Jennifer C, Grice, I Darren, Moran, Anthony P, Korolik, Victoria“…The structure of the lower-M(r )form contained a β-D-Gal-(1→3)-β-D-GalNAc disaccharide moiety which is consistent with the termini of the GM(1), asialo-GM(1), GD(1), GT(1 )and GQ(1 )gangliosides, however, it did not display GM(1 )mimicry as assessed in blotting studies but was shown in NMR to resemble asialo-GM(1). …”
Publicado 2010
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4354“…On the opposite, only selegiline attenuated kainate receptor mediated increases of excitability. …”
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4355por Winden, Kellen D., Karsten, Stanislav L., Bragin, Anatol, Kudo, Lili C., Gehman, Lauren, Ruidera, Josephine, Geschwind, Daniel H., Engel, Jerome“…Here, we performed transcriptomic analysis in the intrahippocampal kainate model of temporal lobe epilepsy in rats using both Agilent and Codelink microarray platforms to characterize the epileptic processes. …”
Publicado 2011
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4356por Ryan, Christopher M., Mehlert, Angela, Richardson, Julia M., Ferguson, Michael A. J., Johnson, Patricia J.“…We have analyzed the structure of this glycoconjugate, previously described to contain the sugars rhamnose (Rha), N-acetylglucosamine (GlcNAc), galactose (Gal), xylose (Xyl), N-acetylgalactosamine (GalNAc), and glucose (Glc), using gas chromatograph mass spectrometry (GC-MS), matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF), electrospray MS/MS, and nuclear magnetic resonance (NMR), combined with chemical and enzymatic digestions. …”
Publicado 2011
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4357“…METHODOLOGY/PRINCIPAL FINDINGS: To address this hypothesis we use rat hippocampal slices and kainate-induced gamma oscillations. Local field potential recordings as well as intracellular recordings of pyramidal cells, fast-spiking and non-fast-spiking interneurons were carried out. …”
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4358“…Non-NMDA L-GluR antagonists that preferentially block alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid (AMPA)/kainate receptors significantly increased D-Asp currents, suggesting a possible allosteric potentiating effect of these antagonists on D-Asp receptors. …”
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4359por Chu, Chun-Ping, Jin, Wen-Zhe, Bing, Yan-Hua, Jin, Qing-Hua, Kannan, Hiroshi, Qiu, De-Lai“…SCP-induced inhibition persisted in the presence of a mixture of TTX, a voltage-gated Na+ channel blocker, CNQX, an AMPA/kainate receptor antagonist and bicuculline, a GABA(A) receptor antagonist, whereas SCP-induced excitation of PVN neurons was reversed by the mixture. …”
Publicado 2013
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4360por Zhao, Jian-Li, Zhang, Lu, Dayanandan, Selvadurai, Nagaraju, Shivaprakash, Liu, Dong-Mei, Li, Qiao-Ming“…METHODS: We analyzed nucleotide sequence data of two chloroplast DNA (cpDNA: atpB-rbcL and trnD-trnT) regions and genotype data of six nuclear microsatellites from 15 populations (140 and 363 individuals, respectively) distributed in Indochina Peninsular and Hainan Island to infer the patterns of genetic diversity and phylogeographic structure. …”
Publicado 2013
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