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4361“…These anatomical findings were corroborated by a pregnancy-related increase in the frequency of kainate-induced CA3 γ oscillations in vitro that could be countered by the NMDA-R antagonists D-AP5 and PPDA. …”
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4362por Kirchheim, Florian, Tinnes, Stefanie, Haas, Carola A., Stegen, Michael, Wolfart, Jakob“…An in vivo mouse model of TLE consisting of intrahippocampal kainate (KA) injection was used to examine epilepsy-related plasticity. …”
Publicado 2013
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4363por Lagranha, Valeska Lizzi, Matte, Ursula, de Carvalho, Talita Giacomet, Seminotti, Bianca, Pereira, Carolina Coffi, Koeller, David M., Woontner, Michael, Goodman, Stephen I., de Souza, Diogo Onofre Gomes, Wajner, Moacir“…We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as well as of the glutamate transporters GLAST and GLT1 in cerebral cortex and striatum of wild type (WT) and glutaryl-CoA dehydrogenase deficient (Gchh (-/-)) mice aged 7, 30 and 60 days. …”
Publicado 2014
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4364“…The effects of N-Methyl-D-aspartic acid (NMDA) and 2-amino-3-(5-methyl-3-oxo-1,2- oxazol-4-yl)propanoic acid (AMPA)/kainate receptor antagonists, MK-801, and 6,7-dinitroquinoxaline-2,3-dione (DNQX), on cell survival were assessed. …”
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4365por Mushtaq, M. M. H., Pasha, T. N., Saima, Akram, M., Mushtaq, T., Parvin, R., Farooq, U., Mehmood, S., Iqbal, K. J., Hwangbo, J.“…The diets supplemented with Na(2)SO(4) to attain higher levels of dNa showed highest BW gain and feed intake (FI) during d 1 to 10 (interaction effects) while 2.6 g/kg dNa exhibited improved BW gain and gain:feed (FG) during d 11 to 20. …”
Publicado 2013
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4366por Schauwecker, Paula Elyse“…Three interval-specific congenic lines were developed, in which either segments of C57BL/6J Chr 18 or C57BL/6J Chr 15 were introduced in the FVB/NJ genetic background, and progeny were treated with kainate and examined for the extent of seizure-induced cell death. …”
Publicado 2014
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4367por Dynnik, Vladimir V., Kononov, Alexey V., Sergeev, Alexander I., Teplov, Iliya Y., Tankanag, Arina V., Zinchenko, Valery P.“…Accelerated network activity may be suppressed by the blockade of NMDA or AMPA/kainate-receptors or by overactivation of AMPA/kainite-receptors. …”
Publicado 2015
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4368“…Sialyltransferase ST3GAL-1, which adds a sialic acid in an α-2,3 linkage to Gal β1,3 GalNAc, preforms an important role in modulating cellular behaviors. …”
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4369por Yang, Jin-Quan, Hsu, Kui-Ching, Liu, Zhi-Zhi, Su, Li-Wei, Kuo, Po-Hsun, Tang, Wen-Qiao, Zhou, Zhuo-Cheng, Liu, Dong, Bao, Bao-Long, Lin, Hung-Du“…The results of a statistical dispersal-vicariance analysis suggested that the ancestral populations of G. orientalis were distributed south of the Yunkai Mountains, including on Hainan Island. The mtDNA data revealed a strong relationship between phylogeny and geography. …”
Publicado 2016
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4370por Zhang, Bin, Ye, Weijun, Ren, Deyong, Tian, Peng, Peng, Youlin, Gao, Yang, Ruan, Banpu, Wang, Li, Zhang, Guangheng, Guo, Longbiao, Qian, Qian, Gao, Zhenyu“…RESULTS: The pair-wise correlation analysis was conducted on length, width and length-width ratio of the flag leaf, and yield per plant in the core recombinant inbred lines of Liang-You-Pei-Jiu (LYP9) developed in Hainan and Hangzhou. There were significant correlations among the three flag leaf size and shape traits. …”
Publicado 2015
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4371por Dong, Haijiao, Zhao, Hu, Xie, Weibo, Han, Zhongmin, Li, Guangwei, Yao, Wen, Bai, Xufeng, Hu, Yong, Guo, Zilong, Lu, Kai, Yang, Lin, Xing, Yongzhong“…We identified 7 common quantitative trait loci (QTLs), including the previously reported major gene Tiller Angle Control 1 (TAC1), in the two environments, 10 and 13 unique QTLs in Hainan and Wuhan, respectively. More QTLs were identified in indica than in japonica, and three major QTLs (qTA3, qTA1b/DWARF2 (D2) and qTA9c/TAC1) were fixed in japonica but segregating in indica, which explained the wider variation observed in indica compared with that in japonica. …”
Publicado 2016
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4372por Song, Zi-Chao, Miao, Han, Zhang, Song, Wang, Ye, Zhang, Sheng-Ping, Gu, Xing-Fang“…These were grown at two field sites, Hainan, with a tropical marine climate, in December 2014, and Beijing, with a warm temperate climate, in May 2015. …”
Publicado 2016
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4373por Zhao, Ran, Qin, Wenjun, Qin, Ruihuan, Han, Jing, Li, Can, Wang, Yisheng, Xu, Congjian“…The gene expression array analysis revealed increased expression of Fut8, B3gnt4, B3gnt5, B4galt2 and decreased expression of Fut1 and ST6GalNAc 6 expression were evident in the A2780-cp cells. …”
Publicado 2017
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4374por Anugraham, Merrina, Jacob, Francis, Everest‐Dass, Arun V., Schoetzau, Andreas, Nixdorf, Sheri, Hacker, Neville F., Fink, Daniel, Heinzelmann‐Schwarz, Viola, Packer, Nicolle H.“…The MS profiling by PGC‐LC also revealed several glycan structural isomers that corresponded to LacdiNAc‐type (GalNAcβ1‐4GlcNAc) motifs that were unique to the serous ovarian cancers and that correlated with elevated gene expression of B4GALNT3 and B4GALNT4 in patients with serous cancer. …”
Publicado 2017
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4375“…WS is negatively correlated with PM(2.5) everywhere except for Hainan Island. PS has a strong positive relationship with PM(2.5) concentration in northeast China and mid-south China, and in other areas the correlation is weak. …”
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4376por Song, Young Min, Kim, Myeong Hyeon, Kim, Ha Na, Jang, Insurk, Han, Jeong Hee, Fontamillas, Giselle Ann, Lee, Chul Young, Park, Byung-Chul“…RESULTS: There was no difference in daily gain, gain:feed, and diarrhea score between the SZ group and either of NC and PC. …”
Publicado 2018
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4377“…Birds were fed a control diet, calculated to contain adequate levels of all nutrients without (C) or with MI supplementation (C+MI), or one of 3 experimental diets that differed in phytase level (modified E. coli-derived 6-phytase; Phy500, Phy1500, or Phy3000 FTU/kg), with P and Ca levels adapted to the recommendations of the phytase supplier for a phytase level of 500 FTU/kg. The gain:feed ratio (G:F) was increased by MI or phytase in the starter+grower phase by 0.02 g/g. …”
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4378por Schiavon, Stefano, Dalla Bona, Mirco, Carcò, Giuseppe, Carraro, Luca, Bunger, Lutz, Gallo, Luigi“…Restricted feeding decreased feed intake (-7%), daily gain (-5%), carcass weight (-2.6%) and back-fat depth (-8.0%) but increased gain:feed ratio (+2%). …”
Publicado 2018
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4379por Bojarová, P., Tavares, M. R., Laaf, D., Bumba, L., Petrásková, L., Konefał, R., Bláhová, M., Pelantová, H., Elling, L., Etrych, T., Chytil, P., Křen, V.“…HPMA nanocarriers decorated with varying amounts of Gal-3 specific epitope GalNAcβ1,4GlcNAc (LacdiNAc) were analyzed in a competitive ELISA-type assay and their binding kinetics was described by surface plasmon resonance. …”
Publicado 2018
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4380por Errico, Francesco, Nuzzo, Tommaso, Carella, Massimo, Bertolino, Alessandro, Usiello, Alessandro“…Along with its direct effect on NMDARs, d-aspartate can also evoke considerable l-glutamate release in specific brain areas through the presynaptic activation of NMDA, AMPA/kainate and mGlu5 receptors. d-aspartate is enriched in the embryonic brain of rodents and humans and its concentration strongly decreases after birth, due to the post-natal expression of the catabolising enzyme d-aspartate oxidase (DDO). …”
Publicado 2018
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