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  1. 4381
    “…One pathogenic fungus, referred to as ND8, was isolated from the wild-type red-fleshed pitaya (Hylocereus polyrhizus) of Hainan Province. In the early stages of this disease, stems show little spots and a loss of green color. …”
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    Transcriptomic de novo analysis of pitaya (Hylocereus polyrhizus) canker disease caused by Neoscytalidium dimidiatum
  2. 4382
    “…A novel actinobacterium, strain HNM0039(T), was isolated from a marine sponge sample collected at the coast of Wenchang, Hainan, China and its polyphasic taxonomy was studied. …”
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    Streptomyces tirandamycinicus sp. nov., a Novel Marine Sponge-Derived Actinobacterium With Antibacterial Potential Against Streptococcus agalactiae
  3. 4383
    “…Furthermore, we also studied morning vs. evening densities of muscarinic, GABA(A), D(1)-like, D(2)-like, NMDA and kainate receptors using autoradiography in the motor, somatosensory and visual cortex and in the striatum, thalamus, hippocampus, pons, and medulla oblongata. …”
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    Variability in the Drug Response of M(4) Muscarinic Receptor Knockout Mice During Day and Night Time
  4. 4384
    “…METHODS: We examined the effects of liver-targeted GalNAc(3)-conjugated antisense oligonucleotide (ASO)-mediated silencing of Pnpla3 in a knock-in mouse model in which we introduced the human PNPLA3 I148M mutation. …”
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    Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
  5. 4385
    “…Moreover, isolates from patients in Hainan (N = 19), Guangdong (N = 1), Guangxi (N = 3) province of China as well as in Australia (N = 3) and Thailand (N = 1) were retrospectively confirmed by the newly developed method. …”
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    Rapid detection of Burkholderia pseudomallei with a lateral flow recombinase polymerase amplification assay
  6. 4386
    “…To improve doctor retention, health systems and employers must mitigate a gainst the emergence of extreme work in healthcare. …”
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    ‘Everything was just getting worse and worse’: deteriorating job quality as a driver of doctor emigration from Ireland
  7. 4387
    “…Unexpectedly, T39 ASO treatment protected against diet-induced obesity. The reduced weight gain was seen with two different ASOs that decreased T39 mRNA in adipose tissue macrophages (ATMs), but not with a liver-targeted GalNac-ASO. …”
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    Antisense oligonucleotide treatment produces a type I interferon response that protects against diet-induced obesity
  8. 4388
    “…DESIGN: A cross-sectional population-based study. SETTING: Hainan Province in the south of China. PARTICIPANTS: 1,278 adults aged 80 years or older. …”
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    Health-Related Quality of Life and Associated Factors Among Oldest-Old in China
  9. 4389
    “…This potentiation of coupling did not require exogenous expression of glutamate receptors, but could be accomplished by endogenously expressed glutamate receptors with pharmacological characteristics reminiscent of NMDA and kainate receptors. Analysis of RNA Sequencing data from HeLa cells confirmed expression of NMDA receptor subunits NR1, NR2C, and NR3B. …”
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    Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions
  10. 4390
    “…Dry matter intake (average: 9.34 kg/d) did not differ (P > 0.05) among diets. Average daily gain tended to increase linearly as DA increased (control: 1.82; LowDA: 1.87; and HighDA: 1.95 kg/d; P < 0.09), but gain:feed ratio was not affected. …”
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    Impact of a phytogenic feed additive on growth performance, feed intake, and carcass traits of finishing steers
  11. 4391
    “…We revealed that Theaceae species richness is highest in southeastern China and on Hainan Island, reaching its highest value (137 species) in Fujian Province. …”
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    Climate change‐induced migration patterns and extinction risks of Theaceae species in China
  12. 4392
    “…METHODS: The clinical manifestations, laboratory parameters, and CT imaging findings were analyzed in 34 COVID-19 patients, confirmed by RT-PCR from January 20 to February 4 in Hainan Province. CT scores were compared between the discharged patients and the ICU patients. …”
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    Early chest CT features of patients with 2019 novel coronavirus (COVID-19) pneumonia: relationship to diagnosis and prognosis
  13. 4393
    “…Genes under selection were identified as Cytochrome P450 2c15 (also recovered in the FUSTr analysis), Niemann 2 Pick C1-like, and Kainate 2 isoform X1. CONCLUSIONS: We have generated eight draft transcriptomes for a closely related and ecologically diverse group of trapdoor spiders, identifying venom gene families potentially under selection across the Aptostichus atomarius complex and chemosensory-associated gene families under selection in dune endemic lineages.…”
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    Shifting evolutionary sands: transcriptome characterization of the Aptostichus atomarius species complex
  14. 4394
    “…The tumor cell treatments mostly affected either static or dynamic as well as either h- or m-selectin interaction. mESel showed a higher diversity of potential ligands than hESel. Inhibition of O-GalNAc-glycosylation also affected glycosphingolipid synthesis. …”
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    Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions
  15. 4395
    “…Examining cell-surface glycomes, IFNα increases levels of the immunosuppressive GalNAc-containing glycans (T/Tn antigens) on CD8(+) T cells. …”
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    Interferon-α alters host glycosylation machinery during treated HIV infection
  16. 4396
    “…Among the selected genes LYN, GLP1R, FOX1, TBK1, STRAP, ST6GALNAC, and Wnt signaling pathways were related to immunity. …”
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    Identifying Signatures of Selection Related to Comb Development
  17. 4397
    “…The ESCC patients showed higher levels of GalNAc and Gal, sialic acid, and GlcNAc expression profiles and lower levels of mannose and fucose expression profiles. …”
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    The Abnormal Glycopatterns of Salivary Glycoproteins in Esophageal Squamous Cell Carcinoma Patients
  18. 4398
    “…Anti-GM1, anti-GD1a, anti-GalNAc-GD1a, and anti-GD1b IgG ganglioside antibodies were more commonly detected in the axonal GBS subtype, whereas the anti-GQ1b and anti-GT1a IgG ganglioside antibodies were more common in classic MFS and its subtypes. …”
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    Determining the Utility of the Guillain-Barré Syndrome Classification Criteria
  19. 4399
    “…METHODS: A total of 254 pregnant women with twin pregnancies, who were admitted to Hainan General Hospital and underwent maternity examination, were selected as the study subjects from January 2015 to December 2018. …”
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    Significance of highly phosphorylated insulin-like growth factor binding protein-1 and cervical length for prediction of preterm delivery in twin pregnancies
  20. 4400
    “…We detected all canonical iGluR splice junctions, assessed the abundance of alternative events described in the literature, and identified new splice events in AMPA, kainate, delta, and NMDA receptor subunits. Notable events include an abundant transcript encoding the GluA4 amino-terminal domain, GluA4-ATD, a novel C-terminal GluD1 (delta receptor 1) isoform, GluD1-b, and potentially new GluK4 and GluN2C isoforms. …”
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    Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data
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