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4441“…The PC group showed the highest ADG and ADFI, whereas gain:feed was improved in the PC and T1 group (p<0.05). …”
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4442por Beecham, Gary W., Hamilton, Kara, Naj, Adam C., Martin, Eden R., Huentelman, Matt, Myers, Amanda J., Corneveaux, Jason J., Hardy, John, Vonsattel, Jean-Paul, Younkin, Steven G., Bennett, David A., De Jager, Philip L., Larson, Eric B., Crane, Paul K., Kamboh, M. Ilyas, Kofler, Julia K., Mash, Deborah C., Duque, Linda, Gilbert, John R., Gwirtsman, Harry, Buxbaum, Joseph D., Kramer, Patricia, Dickson, Dennis W., Farrer, Lindsay A., Frosch, Matthew P., Ghetti, Bernardino, Haines, Jonathan L., Hyman, Bradley T., Kukull, Walter A., Mayeux, Richard P., Pericak-Vance, Margaret A., Schneider, Julie A., Trojanowski, John Q., Reiman, Eric M., Schellenberg, Gerard D., Montine, Thomas J.“…Genome-wide significance was observed for clinico-pathologic AD dementia, NPs, NFTs, CAA, and LBD with a number of variants in and around the apolipoprotein E gene (APOE). GalNAc transferase 7 (GALNT7), ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1), and an intergenic region on chromosome 9 were associated with NP score; and Potassium Large Conductance Calcium-Activated Channel, Subfamily M, Beta Member 2 (KCNMB2) was strongly associated with HS. …”
Publicado 2014
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4443por Kleiner-Fisman, Galit, Khoo, Edwin, Moncrieffe, Nikohl, Forbell, Triina, Gryfe, Pearl, Fisman, David“…No significant treatment effect was found for GAS, VAS and PAINAD scales or change in time to perform care. No adverse drug reactions occurred. …”
Publicado 2014
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4444“…In contrast, the kdr alleles were less frequent in the samples from other regions, especially in Yunnan and Hainan, despite the documented presence of pyrethroid resistant populations in those regions. …”
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4445“…The average daily feed intake during the nursery phase was greater (p <0.01) in the HIGH group than in the MEDIUM and LOW groups, whereas the gain:feed ratio did not differ across the treatments. …”
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4446“…OBJECTIVE: The aim of this study was to evaluate the effects of an oral supplement rich in specific antioxidants, SkinAx(2TM), on the improvement of the skin radiance in women. …”
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4447por Zhao, Xiwu, Reifler, Aaron N., Schroeder, Melanie M., Jaeckel, Elizabeth R., Chervenak, Andrew P., Wong, Kwoon Y.“…We find that the sustained nature of ipRGCs’ rod/cone-driven responses depends neither on melanopsin nor on N-methyl-d-aspartate (NMDA) receptors, whereas the transience of the direction-selective cells’ responses is influenced neither by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptor desensitization nor by glutamate uptake. …”
Publicado 2017
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4448por Leker, Kristy, Lozano-Pope, Ivonne, Bandyopadhyay, Keya, Choudhury, Biswa P., Obonyo, Marygorret“…RESULTS: The major difference between the two strains of H. pylori is the presence of Rhamnose, Fucose and GalNAc in the SS1 strain, which was either not found or with low abundance in the G27 strain. …”
Publicado 2017
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4449por Chen, Yufeng, Zhou, Dengbo, Qi, Dengfeng, Gao, Zhufen, Xie, Jianghui, Luo, Yanping“…An actinomycete strain, CB-75, was isolated from the soil of a diseased banana plantation in Hainan, China. Based on phenotypic and molecular characteristics, and 99.93% sequence similarity with Streptomyces spectabilis NBRC 13424 (AB184393), the strain was identified as Streptomyces sp. …”
Publicado 2018
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4450“…METHODS: Cultured rat spinal cord astrocytes were treated with kainate and scratching to generate an in vitro model of SCI. …”
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4451A set of cancer stem cell homing peptides associating with the glycan moieties of glycosphingolipids“…CSC HP-10, CSC HP-11 and CSC HP-hP2 could associate with the disialylated saccharide Neu5Ac-α-2,6-Gal-β-1,3-(Neu5Ac-α-2,6)-GalNAc coupled on a microarray chip. These results indicate that the CSC HPs may target to the known stem cell glycan markers GbH and Lewis Y as well as the disialylated saccharide.…”
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4452por Hossain, Md Kamal, Vartak, Abhishek, Karmakar, Partha, Sucheck, Steven J., Wall, Katherine A.“…The vaccine conjugate contained Pam(3)CysSK(4), a Toll-like receptor (TLR) agonist linked via copper-free cycloaddition chemistry to a 20-amino-acid glycopeptide derived from the tumor marker MUC-1 containing the tumor-associated carbohydrate antigen α-N-acetyl galactosamine (GalNAc). The primed CD8+ T cells released IFN-γ and killed tumor cells. …”
Publicado 2018
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4453por Segura, Audrey, Bertoni, Marine, Auffret, Pauline, Klopp, Christophe, Bouchez, Olivier, Genthon, Clémence, Durand, Alexandra, Bertin, Yolande, Forano, Evelyne“…Additional carbohydrates (xylose, ribose, mannitol, galactitol) as well as gluconeogenic substrates (aspartate, serine, glycerol) would also be used by EHEC as carbon and/or nitrogen sources all along the bovine GIT including the rumen. However, xylose, GalNac, ribose and fucose transport and/or assimilation encoding genes were over-expressed during incubation in rectum content compared with rumen and intestine contents, and genes coding for maltose transport were only induced in rectum. …”
Publicado 2018
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4454por Liu, Fu-Mei, Zhang, Ning-Nan, Liu, Xiao-Jin, Yang, Zeng-Jiang, Jia, Hong-Yan, Xu, Da-Ping“…Chen (Fabaceae) is a woody tree species indigenous to Hainan Island in China. Due to its high medicinal and commercial value, this tree species has been planted over 3500 ha(2) in southern China. …”
Publicado 2019
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4455por Song, Xingyue, Wu, Jing, Yu, Canqing, Dong, Wenhong, Lv, Jun, Guo, Yu, Bian, Zheng, Yang, Ling, Chen, Yiping, Chen, Zhengming, Pan, An, Li, Liming“…METHODS: Survey of 57,693 men and 67,089 women aged 60 years and above was conducted in five rural (Gansu, Sichuan, Hunan, Henan, Zhejiang) and five urban areas (Heilongjiang, Shandong, Jiangsu, Guangxi, Hainan) in China between 2004 and 2008. Logistic regression models were used to calculate the relations of different factors with global SRH and age-comparative SRH. …”
Publicado 2019
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4456“…RESULTS: Three sequences from similar post-translational modifications (PTMs) of proteins occurring at, or very near, the S/T-site are analyzed: N-glycosylation, O-mucin type (O-GalNAc) glycosylation, and phosphorylation. Results found include: 1) The consensus composite sequon for O-glycosylation is: ~(W–S/T–W), where “~” denotes the “not” operator. 2) The consensus sequon for phosphorylation is ~(W–S/T/Y/H–W); although W–S/T/Y/H–W is not an absolute inhibitor of phosphorylation. 3) For linear probability model (LPM) estimation, N-glycosylated sequences are good approximations to non-O-glycosylatable sequences; although N – ~P – S/T is not an absolute inhibitor of O-glycosylation. 4) The selective positioning of an amino acid along the sequence, differentiates the PTMs of proteins. 5) Some N-glycosylated sequences are also phosphorylated at the S/T-site in the N – ~P – S/T sequon. 6) ASA values for N-glycosylated sequences are stochastically larger than those for O-GlcNAc glycosylated sequences. 7) Structural attributes (beta turn II, II´, helix, beta bridges, beta hairpin, and the phi angle) are significant LPM predictors of O-GlcNAc glycosylation. …”
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4457por Detzner, Johanna, Gloerfeld, Caroline, Pohlentz, Gottfried, Legros, Nadine, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes“…Stx2e targets endothelial cells of animal organs including the kidney harboring the Stx receptor glycosphingolipids (GSLs) globotriaosylceramide (Gb3Cer, Galα1-4Galβ1-4Glcβ1-1Cer) and globotetraosylceramide (Gb4Cer, GalNAcβ1-3Galα1-4Galβ1-4Glcβ1-1Cer). Since the involvement of renal epithelial cells in the edema disease is unknown, in this study, we analyzed the porcine kidney epithelial cell lines, LLC-PK1 and PK-15, regarding the presence of Stx-binding GSLs, their sensitivity towards Stx2e, and the inhibitory potential of Gb3- and Gb4-neoglycolipids, carrying phosphatidylethanolamine (PE) as the lipid anchor, towards Stx2e. …”
Publicado 2019
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4458por Behuet, Sabrina, Cremer, Jennifer Nadine, Cremer, Markus, Palomero-Gallagher, Nicola, Zilles, Karl, Amunts, Katrin“…Receptor densities of the ionotropic glutamatergic receptors α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate and N-methyl-D-aspartate (NMDA) as well as of the ionotropic GABA(A) and metabotropic GABA(B) receptors were investigated using specific high-affinity ligands. …”
Publicado 2019
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4459por Visnapuu, Triinu, Teze, David, Kjeldsen, Christian, Lie, Aleksander, Duus, Jens Øllgaard, André-Miral, Corinne, Pedersen, Lars Haastrup, Stougaard, Peter, Svensson, Birte“…The kinetic parameters of PhNah20A for p-nitrophenyl-GlcNAc and p-nitrophenyl-GalNAc were highly similar: k(cat)/K(M) being 341 and 344 mM(−1)·s(−1), respectively. …”
Publicado 2020
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4460“…RESULTS: While no significant differences in body weight, daily gain, daily feed intake nor gain:feed were observed between control and treatment animals (P > 0.05), an effect of Peptiva on the fecal bacterial composition of weaned pigs was observed. …”
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