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261por Hernandez, Rafael J., Hesse, Elze, Dowling, Andrea J., Coyle, Nicola M., Feil, Edward J., Gaze, Will H., Vos, Michiel“…We describe the first use of the Wax moth larva Galleria mellonella, a well-established model for the mammalian innate immune system, to selectively enrich and characterize pathogens from coastal environments in the South West of the UK. …”
Publicado 2019
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262por Maurer, Elisabeth, Hörtnagl, Caroline, Lackner, Michaela, Grässle, Denise, Naschberger, Verena, Moser, Patrizia, Segal, Esther, Semis, Margarita, Lass-Flörl, Cornelia, Binder, Ulrike“…Mucorales can cause cutaneous to deep-seated infections, mainly in the immunocompromised host, resulting in high mortality rates due to late and inefficient treatment. In this study, Galleria mellonella larvae were evaluated as a heterologous invertebrate host to study pathogenicity of clinically relevant mucormycetes (Rhizopus spp., Rhizomucor spp., Lichtheimia spp., Mucor spp.). …”
Publicado 2019
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263por Polenogova, Olga V., Kabilov, Marsel R., Tyurin, Maksim V., Rotskaya, Ulyana N., Krivopalov, Anton V., Morozova, Vera V., Mozhaitseva, Kseniya, Kryukova, Nataliya A., Alikina, Tatyana, Kryukov, Vadim Yu., Glupov, Viktor V.Enlace del recurso
Publicado 2019
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264por Ren, Liu, Men, Lina, Zhang, Zhiwei, Guan, Feifei, Tian, Jian, Wang, Bin, Wang, Jihua, Zhang, Yuhong, Zhang, Wei“…D1 was isolated from the guts of wax moth (Galleria mellonella). Microbial colonies formed around a PE film after 14 days of cultivation with D1. …”
Publicado 2019
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265“…Five separate diets – beeswax (BW), glycerol (Gly), and three types of dog croquettes (DC1, DC2, and DC3) – were used to rear larvae of the greater wax moth, Galleria mellonella. The larvae were later inoculated with five different isolates of entomopathogenic nematodes (EPN) emerging from the insect larvae reared on the five diets. …”
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266“…Therefore, levels of lethality of defined hvKp and cKp strain cohorts were compared in Galleria and outbred mouse models. The murine model, but not the G. mellonella model, accurately differentiated hvKp from cKp strains. …”
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267por Sowa-Jasiłek, Aneta, Zdybicka-Barabas, Agnieszka, Stączek, Sylwia, Pawlikowska-Pawlęga, Bożena, Grygorczuk-Płaneta, Katarzyna, Skrzypiec, Krzysztof, Gruszecki, Wiesław I., Mak, Paweł, Cytryńska, Małgorzata“…The action of a unique Galleria mellonella anionic peptide 2 (AP2) against fungal pathogen Candida albicans was examined using different microscopic techniques and Fourier transform infrared (FTIR) spectroscopy. …”
Publicado 2020
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268por Jemel, Sana, Guillot, Jacques, Kallel, Kalthoum, Botterel, Françoise, Dannaoui, Eric“…To circumvent these limitations, alternative invertebrate models, such as Galleria mellonella, have been developed. Larvae of G. mellonella have been widely used for testing virulence of fungi and more recently have proven useful for evaluation of antifungal efficacy. …”
Publicado 2020
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269“…In this study, we employed the Galleria mellonella larvae model to evaluate virulence potential of fifteen clinical, environmental and food isolates of L. monocytogenes, related to three major outbreaks, after growth on different foods. …”
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270“…This study detailed the responses of Galleria mellonella larvae to disseminated infection caused by co-infection with Candida albicans and Staphylococcus aureus . …”
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271por Kovacs-Simon, Andrea, Metters, Georgie, Norville, Isobel, Hemsley, Claudia, Titball, Richard W.“…Larvae of the greater wax moth (Galleria mellonella) are susceptible to infection with C. burnetii, an obligate intracellular bacterial pathogen. …”
Publicado 2020
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272por Huang, Xiao-Wen, Xu, Mei-Nian, Zheng, Huan-Xin, Wang, Meng-Lei, Li, Li, Zeng, Kang, Li, De-Dong“…Unlike the high pathogenicity of C. albicans, C. glabrata is reported to show low pathogenicity to the host. Here, by using a Galleria mellonella infection model, we were able to confirm the much lower virulence of C. glabrata than C. albicans. …”
Publicado 2020
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273“…Furthermore, we use the Galleria mellonella larvae model to assess toxicity of the compound and its efficacy in treating infections in a live host. …”
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274por Ménard, Guillaume, Rouillon, Astrid, Ghukasyan, Gevorg, Emily, Mathieu, Felden, Brice, Donnio, Pierre-Yves“…Insufficient in vivo studies monitoring sRNA expression attest to the difficulties in collecting such data, we therefore developed a non-mammalian infection model using larval Galleria mellonella to analyze the roles of Staphylococcus aureus sRNAs during larval infection and to quickly determine possible sRNA involvement in staphylococcal virulence before proceeding to more complicated animal testing. …”
Publicado 2021
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275por Dijokaite, Aiste, Humbert, Maria Victoria, Borkowski, Emma, La Ragione, Roberto M, Christodoulides, Myron“…The focus of the current study was to examine the utility of the invertebrate greater wax moth Galleria mellonella as an in vivo model of gonococcal infection. …”
Publicado 2021
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276“…In this study, the complete mitochondrial genome of Schizoneuraphis gallarum was sequenced and annotated. The mitogenome is 14,990 bp in length with an A + T content of 82.6%, including 13 protein-coding genes, 22 transfer RNA genes, two ribosomal RNA genes and a control region. …”
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277“…Research has demonstrated that the larvae of Tenebrio molitor (yellow mealworm), Galleria mellonella (greater wax moth), and Zophobas atratus (superworm) possess a biodegradation ability for polystyrene (PS) within the gut microbiota of these organisms. …”
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278por Grizanova, Ekaterina V., Coates, Christopher J., Dubovskiy, Ivan M., Butt, Tariq M.“…Herein, we explored the interactions between the fungal pathogen Metarhizium brunneum ARSEF 4556 and two immunologically distinct morphs, melanic (M) and non-melanic (NM), of the greater wax moth Galleria mellonella. We first interrogated the cuticular compositions of both insect morphs to reveal substantial differences in their physiochemical properties. …”
Publicado 2019
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279“…OBJECTIVES: Galleria mellonella assimilates beeswax using many gut enzymes; however, high doses of gamma radiation have been used to eradicate such pests, affecting its life cycle. …”
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280por de Souza Pitangui, Nayla, Fernandes, Fabrício Freitas, Aparecido da Silva, Thiago, Gonçales, Relber Aguiar, Roque-Barreira, Maria Cristina“…Using a paracoccidioidomycosis model developed in Galleria mellonella larvae, we confirmed the observation, in the murine host, that ov-PCN yeasts display maximum virulence compared to wild-type (wt-PCN) or PCN-silenced (kd-PCN) yeasts. …”
Publicado 2023
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