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5341por Morales-Laverde, Liliana, Echeverz, Maite, Trobos, Margarita, Solano, Cristina, Lasa, Iñigo“…In contrast, an SNP within the icaR coding region, resulting in a V176E change in the transcriptional repressor IcaR, led to a significant increase in icaADBC operon transcription and PIA/PNAG production and a reduction in S. aureus virulence in a Galleria mellonella infection model. In conclusion, SNPs in icaADBCR IGRs of S. aureus isolates from PJI are not associated with icaADBC expression, PIA/PNAG production and adaptation to PJI.…”
Publicado 2022
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5342por Lazarini, Josy Goldoni, Massarioli, Adna Prado, Soares, Jackeline Cintra, Nani, Bruno Dias, Charo, Nancy, Oliveira, Douglas Souza, Camargo, Lauren, Alvarez-Flores, Miryam Paola, Batista, Isabel de Fátima Correia, Chudzinski-Tavassi, Ana Marisa, Alencar, Severino Matias de, Franchin, Marcelo, Rosalen, Pedro Luiz“…The composition of S8 was assessed by LC-ESI-QTOF-MS; the anti-inflammatory activity in RAW264.7 macrophages through NF-κB activation and biomarkers by multiplex in THP-1 cells; neutrophil migration, intravital microscopy and ICAM-1 expression in mice; NETs formation and CD11b expression; S8 scavenging capacity of ROS/RNS; toxicity in Galleria mellonella larvae model. Coumaric acid, quercetrin and vanillic acid were identified. …”
Publicado 2022
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5343por Mendes, Soraia R., Eckhard, Ulrich, Rodríguez-Banqueri, Arturo, Guevara, Tibisay, Czermak, Peter, Marcos, Enrique, Vilcinskas, Andreas, Gomis-Rüth, F. Xavier“…The greater wax moth Galleria mellonella produces a unique defensive protein known as the insect metallopeptidase inhibitor (IMPI), which selectively inhibits some thermolysins from pathogenic bacteria. …”
Publicado 2022
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5344por Guan, Yi, Wang, Donghuang, Lin, Xiaofeng, Li, Xin, Lv, Chao, Wang, Dingyi, Zhang, Longbin“…Deletion of cdc42 in B. bassiana resulted in a great loss of virulence to Galleria mellonella, a model insect, via normal cuticle infection as well as defects in conidial germination, radial growth, aerial conidiation, and conidial tolerance to heat and UVB irradiation. …”
Publicado 2022
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5345por Andrade, Mariana, Oliveira, Ketlyn, Morais, Catarina, Abrantes, Patrícia, Pomba, Constança, Rosato, Adriana E., Couto, Isabel, Costa, Sofia Santos“…Kaplan–Meier survival analysis of Galleria mellonella infected with different CoPS revealed a higher virulence potential of S. aureus when compared with other CoPS. …”
Publicado 2022
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5346por Sanmukh, Swapnil Ganesh, Admella, Joana, Moya-Andérico, Laura, Fehér, Tamás, Arévalo-Jaimes, Betsy Verónica, Blanco-Cabra, Núria, Torrents, Eduard“…Our results demonstrate that irrespective of host specificity, bacteriophages producing clear plaques with a high burst size, and exhibiting depolymerizing activity, are good candidates against biofilm-producing E. coli pathogens as verified from our in vitro and in vivo experiments using Galleria mellonella where survival was significantly increased for phage-therapy-treated larvae.…”
Publicado 2023
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5347por Karczewska, Monika, Strzelecki, Patryk, Bogucka, Krystyna, Potrykus, Katarzyna, Szalewska-Pałasz, Agnieszka, Nowicki, Dariusz“…Moreover, our virulence analysis showed these phenotypes to be crucial for the development of severe infections in the Galleria mellonella model.…”
Publicado 2023
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5348por Aspell, Tiger, Khemlani, Adrina Hema J., Tsai, Catherine Jia-Yun, Loh, Jacelyn Mei San, Proft, Thomas“…Furthermore, deletion of the genes decreased S. pyogenes virulence in a human whole blood killing assay and a Galleria mellonella (Greater wax moth) larvae infection model. …”
Publicado 2023
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5350por López Medina Ávalos, Paloma“…En esta ocasión, Óscar Armando García, coordinador y editor, Jaime Gallardo y Ricardo García Arteaga, compiladores, y Carlos Solórzano, asesor científico, han conjuntado una selección de obras que contemplan ejemplos selectos de la diversidad de manifestaciones dramáticas en Latinoamérica durante un período que abarca un poco más de tres décadas: desde finales de los años ochenta del siglo XX hasta los albores del siglo XXI. …”
Publicado 2014
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5351por Pintor-Cora, Alberto, Tapia, Olga, Elexpuru-Zabaleta, María, Ruiz de Alegría, Carlos, Rodríguez-Calleja, Jose M., Santos, Jesús A., Ramos-Vivas, Jose“…These interactions were analyzed by confocal microscopy to determine the cytotoxicity of the strains. We also used Galleria mellonella larvae to test their pathogenicity in this experimental model. …”
Publicado 2023
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5352por Calcagnile, Matteo, Jeguirim, Inès, Tredici, Salvatore Maurizio, Damiano, Fabrizio, Alifano, Pietro“…The ability of spiramycin to dampen the virulence of the P. aeruginosa strain was confirmed in a Galleria mellonella animal model. The results demonstrated that when G. mellonella larvae were infected with P. aeruginosa, the mortality after 24 h was >90%. …”
Publicado 2023
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5353por Heslin, Caitlin, Boehm, Daniela, Gilmore, Brendan F., Megaw, Julianne, Freeman, Theresa A., Hickok, Noreen J., Cullen, P. J., Bourke, Paula“…Thus, this study examines the cytotoxic and mutagenic effects of plasma-treated molecules in vitro using CHO-K1 cells and in vivo in Galleria mellonella larvae. Specifically, albumin, glucose, cholesterol, and arachidonic acid were chosen as representative biomolecules, with established involvement in diverse bioprocesses including; cellular respiration, intracellular transport, cell signaling or membrane structure. …”
Publicado 2021
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5354por Sandri, Angela, Saitta, Giulia Maria, Veschetti, Laura, Boschi, Federico, Passarelli Mantovani, Rebeca, Carelli, Maria, Melotti, Paola, Signoretto, Caterina, Boaretti, Marzia, Malerba, Giovanni, Lleò, Maria M.“…Eight clinical isolates were selected based on different pathogenic characteristics previously assessed: virulence in Galleria mellonella larvae, cytotoxicity in human bronchial epithelial cells, and biofilm formation. …”
Publicado 2023
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5355“…Here, we investigated the characteristics of the bacterial population in the late stages of an infection in the B. thuringiensis/Galleria mellonella infection model. Using fluorescent reporters and molecular markers coupled to flow cytometry, we demonstrated that the Spo(–) cells persist and constitute about half of the population 2 weeks post-infection (p.i.). …”
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5356por Irudal, Samuele, Scoffone, Viola Camilla, Trespidi, Gabriele, Barbieri, Giulia, D’Amato, Maura, Viglio, Simona, Pizza, Mariagrazia, Scarselli, Maria, Riccardi, Giovanna, Buroni, Silvia“…We showed that BCAL1524, a collagen-like protein, promotes bacteria auto-aggregation and plays an important role in virulence, in the Galleria mellonella model. BCAM0949, an extracellular lipase, mediates piperacillin resistance, biofilm formation in Luria Bertani and artificial sputum medium, rhamnolipid production, and swimming motility; its predicted lipolytic activity was also experimentally confirmed. …”
Publicado 2023
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5357por Wang, Jianmei, Huang, Yuting, Guan, Chunjiu, Li, Jie, Yang, Hua, Zhao, Guoping, Liu, Canying, Ma, Jiangang, Tang, Biao“…In vivo experiments showed that strain 812A1-131 is pathogenic to Galleria mellonella and could colonize the intestines of mice. …”
Publicado 2023
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5358por Spínola-Amilibia, Mercedes, Illanes-Vicioso, Ramiro, Ruiz-López, Elena, Colomer-Vidal, Pere, Rodriguez-Ventura, Francisco, Peces Pérez, Rosa, Arias, Clemente F., Torroba, Tomas, Solà, Maria, Arias-Palomo, Ernesto, Bertocchini, Federica“…The saliva of the lepidopteran Galleria mellonella larvae is capable of oxidizing and depolymerizing polyethylene in hours at room temperature. …”
Publicado 2023
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5359por Nicolosi, Roberta Maria, Bonincontro, Graziana, Imperia, Elena, Badiali, Camilla, De Vita, Daniela, Sciubba, Fabio, Dugo, Laura, Guarino, Michele Pier Luca, Altomare, Annamaria, Simonetti, Giovanna, Pasqua, Gabriella“…In vivo, prGSE activity using infected Galleria mellonella larvae has been evaluated. The results show that the prGSE, if administered with LPS, can significantly reduce the LPS-induced permeability alteration. …”
Publicado 2023
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5360“…Clinical strains showed comparable virulence in the Galleria mellonella model of infection, irrespective of their status as outbreak or sporadic strains, whereas a non-human isolate was avirulent. …”
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