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7801por Li, Fang, Gao, Chen, Yan, Ping, Zhang, Meng, Wang, Yinghao, Hu, Yue, Wu, Xiaoyun, Wang, Xuanjun, Sheng, Jun“…(-)-Epigallocatechin-3-gallate (EGCG), which is the most abundant catechin in green tea, has many potential health benefits, including decreased weight gain and/or adipose tissue weight. …”
Publicado 2018
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7802“…Three procyanidin dimers (peaks 6, 9 and 10), seven acid derivatives (peaks 1–4, 11, 20 and 21) and four xanthones were identified, mainly mangiferin (peak 12) and mangiferin gallate, (peak 7), which were present in both peel and pulp of the two studied species from northern Chile. …”
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7803“…Next, we tested five other structurally dissimilar bitter compounds, to which mice were naive at the beginning of experiments: denatonium benzoate, quinine-HCl, caffeine, salicin, and epigallocatechin gallate. R(j)T was moderately higher than aR(c)T for all the compounds tested, indicating the presence of innate acceptance to these various, unfamiliar bitter stimuli in mice. …”
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7804por Si, Hongwei, Wang, Xiaoyong, Zhang, Longyun, Parnell, Laurence D., Ahmed, Bulbul, LeRoith, Tanya, Ansah, Twum-Ampofo, Zhang, Lijuan, Li, Jianwei, Ordovás, José M., Si, Hongzong, Liu, Dongmin, Lai, Chao-Qiang“…In the present study, epicatechin or its analogue epigallocatechin gallate (EGCG) (0.25% w/v in drinking water) was administered to 20-mo-old male C57BL mice fed a standard chow. …”
Publicado 2019
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7805“…The synthetic antioxidants, butyl hydroxy anisole (BHA), di-butyl hydroxy toluene (BHT), and propyl gallate, did not exhibit photoprotective effects on these hydrolysable tannins. …”
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7806“…The purpose of this research was to determine the total phenolic, total monomeric anthocyanin, catechin, epicatechin and epigallocatechin gallate content, DPPH radical scavenging activity, and toxicity in rind, flesh, seed, and whole fruit of L. alata. …”
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7807“…Juvenile hormones (JH) are key endocrine regulators produced by the corpora allata (CA) of insects. Together with ecdysteroids, as well as nutritional cues, JH coordinates different aspects of insect postembryonic development and reproduction. …”
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7808por Song, Sung Hwa, Kim, Ji Eun, Sung, Ji Eun, Lee, Hyun Ah, Yun, Woo Bin, Lee, Young Hee, Song, HyunKeun, Hwang, DaeYoun“…The results showed that EtGR consisted of gallotannin (68.7%), gallic acid (27.2%) and methyl gallate (4.1%) and that it had a high antioxidant value (IC50 value; 1.93 μg/mL). …”
Publicado 2018
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7809“…Each group was divided into 2 subgroups according to the type of bone graft material: a biphasic calcium phosphate (BCP) subgroup and an Escherichia coli-derived recombinant human bone morphogenetic protein-2-/epigallocatechin-3-gallate-coated BCP (mBCP) subgroup. Two identical circular defects with a 6-mm diameter were made in the right and left parietal bones of each rat. …”
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7810por Ghareeb, Mosad A., Sobeh, Mansour, El-Maadawy, Walaa H., Mohammed, Hala Sh., Khalil, Heba, Botros, Sanaa, Wink, Michael“…Out of them, 4 polyphenolic compounds were isolated: (1) 4-(O-β-d-xylopyranosyloxy)-3,5-di-hydroxy-benzoic acid, (2) 4-(O-α-l-rhamnopyranosyloxy)-3,5-di-hydroxy-benzoic acid, (3) gallic acid, and (4) methyl gallate. Effects of EG extract on biochemical parameters, gene expression, and immune-histopathological changes were assessed in comparison to mesna positive control. …”
Publicado 2019
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7811Investigation of Hot Spot Region in XIAP Inhibitor Binding Site by Fragment Molecular Orbital Methodpor Lim, Hocheol, Jin, Xuemei, Kim, Jongwan, Hwang, Sungbo, Shin, Ki Beom, Choi, Jiwon, Nam, Ky-Youb, No, Kyoung Tai“…We also performed pair interaction energy decomposition analysis to investigate the binding energies between specific binding residues and individual ligands, showing that the novel natural product neoeriocitrin 10 had a higher binding affinity than epicatechin gallate 9. Molecular docking and dynamics simulations were performed to explore the mode of binding between 10 and XIAP-BIR3, demonstrating that 10 binds more strongly to the P1 and P4 pockets than 9. …”
Publicado 2019
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7812“…Especially, the cytokine production inhibitory activities of TI were found to be similar to the positive control, epigallocatechin gallate (EGCG). CTL and TI enhanced the CE formation and filaggrin mRNA expression levels and showed potent activities compared to that in the positive control, 1.5 mM Ca(2+). …”
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7813por Roomi, M. Waheed, Kalinovsky, Tatiana, Bhanap, Bilwa, Niedzwiecki, Aleksandra, Rath, Matthias“…At near confluence, the cells were washed with phosphate-buffered saline and incubated in serum-free media with PMA; TNF-α, IL-1β; lipopolysaccharide; epigallocatechin gallate (EGCG) and doxycycline (Dox) at various doses with and without PMA; a nutrient mixture (NM) containing lysine, proline, ascorbic acid, and EGCG with and without PMA at; and actinomycin D and cycloheximide at different doses. …”
Publicado 2019
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7814“…Polyphenols such as epigallocatechin gallate (EGCg) may have roles in preventing some chronic diseases when they are ingested as components of plant-based foods and beverages. …”
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7815“…Here we review some of the most promising drugs and agents that have the potential to attenuate TLR-mediated inflammation, e.g., anti-LPS strategies that aim to neutralize LPS (synthetic anti-LPS peptides and recombinant factor C) and TLR4/MyD88 antagonists, including eritoran, CyP, EM-163, epigallocatechin-3-gallate, 6-shogaol, cinnamon extract, N-acetylcysteine, melatonin, and molecular hydrogen. …”
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7816por Punt, Ans, Firman, James, Boobis, Alan, Cronin, Mark, Gosling, John Paul, Wilks, Martin F, Hepburn, Paul A, Thiel, Anette, Fussell, Karma C“…The most obvious activity identified was the estrogen receptor-mediated actions of the chemical group containing parabens and structurally related gallates, as well the chemical group containing genistein and daidzein (the latter 2 being particularly active toward estrogen receptor β as a potential health benefit). …”
Publicado 2020
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7817“…Natural plant products used in traditional medicines for the treatment of glioblastoma contain flavonoids, terpenoids, polyphenols, epigallocatechin gallate, quinones, and saponins, which might serendipitously include agents that modulate some classes of signaling compounds highlighted in this review. …”
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7818por Assumpção, João Henrique Maia, Takeda, Agnes Alessandra Sekijima, Sforcin, José Maurício, Rainho, Cláudia Aparecida“…We selected three phenolic acids (caffeic, dihydrocinnamic, and p-coumaric) commonly detected in propolis and the (−)-epigallocatechin-3-gallate (EGCG) from green tea, which is a well-known DNA demethylating agent, for further analysis. …”
Publicado 2020
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7819por Farooqi, Ammad Ahmad, Pinheiro, Marina, Granja, Andreia, Farabegoli, Fulvia, Reis, Salette, Attar, Rukset, Sabitaliyevich, Uteuliyev Yerzhan, Xu, Baojun, Ahmad, Aamir“…Therapeutic targeting of deregulated oncogenic signaling cascades by products obtained from natural sources has shown promising results. Epigallocatechin-3-gallate (EGCG) has emerged as a distinguished chemopreventive product because of its ability to regulate a myriad of oncogenic signaling pathways. …”
Publicado 2020
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7820“…In the present work, the succinic acid (SA), L-pyroglutamic acid (L-PGA), N-phenyl-thioacetamide (N-NPTA), 2-amino-5-chloropyridine hydrogen succinate (ACPS), epigallocatechine Gallate (EGCG) or KDH and, selenomethionine (SeM) compounds have been proposed as potential antiviral candidates to treatment of COVID-19 based on B3LYP/6-311++G∗∗ calculations and molecular docking. …”
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