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  1. 81
    “…Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious disease models, due to ease of use and the presence of an innate immune system functionally similar to that of vertebrates. …”
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    Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs
  2. 82
    “…Furthermore, we found that another nonvertebrate animal model, Galleria mellonella, can be used to study the pathogenesis of S. anginosus infection, with an emphasis on the interactions between the pathogen and host innate immunity. …”
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    Studies of Streptococcus anginosus Virulence in Dictyostelium discoideum and Galleria mellonella Models
  3. 83
    “…Galleria mellonella is a promising in vivo model insect used for microbiological, medical, and pharmacological research. …”
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    Galleria mellonella—A Model for the Study of aPDT—Prospects and Drawbacks
  4. 84
    “…Galleria mellonella larvae have become a widely accepted and utilised infection model due to the functional homology displayed between their immune response to infection and that observed in the mammalian innate immune response. …”
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    Galleria mellonella Larvae as a Model for Investigating Fungal—Host Interactions
  5. 85
    “…However, these models have limitations whereas the invertebrate Galleria mellonella model is a cost-effective and ethical alternative. …”
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    A novel Galleria mellonella experimental model for zoonotic pathogen Brucella
  6. 86
    “…The aim of this study was to determine the antimicrobial activity of Galleria mellonella defense polypeptides against L. dumoffii. …”
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    Anti-Legionella dumoffii Activity of Galleria mellonella Defensin and Apolipophorin III
  7. 87
    “…The greater wax worm Galleria mellonella, as an alternative model, provides some useful advantages not available with other models and has already been described as suitable for the virulence assessment of various pathogens including L. monocytogenes. …”
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    Assessment of Listeria monocytogenes virulence in the Galleria mellonella insect larvae model
  8. 88
    “…Thus there is an urgent need for the development of new alternative in vivo models. The insect larvae, Galleria mellonella has been increasingly used as a successful, simple, widely available and cost-effective model to study microbial infections. …”
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    Galleria mellonella - a novel infection model for the Mycobacterium tuberculosis complex
  9. 89
    “…Experimentation in mammals is a long and expensive process in which ethical aspects must be considered, which has led the scientific community to develop alternative models such as that of Galleria mellonella. This model is a cost and time effective option to act as a filter in the drug discovery process. …”
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    New solvent options for in vivo assays in the Galleria mellonella larvae model
  10. 90
    “…The restraint of the greater wax moth larvae (Galleria mellonella) is often achieved by grasping a larva firmly between finger and thumb. …”
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    The design and implementation of restraint devices for the injection of pathogenic microorganisms into Galleria mellonella
  11. 91
    “…The growth of Legionella dumoffii can be inhibited by Galleria mellonella apolipophorin III (apoLp-III) which is an insect homologue of human apolipoprotein E., and choline-cultured L. dumoffii cells are considerably more susceptible to apoLp-III than bacteria grown without choline supplementation. …”
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    Choline Supplementation Sensitizes Legionella dumoffii to Galleria mellonella Apolipophorin III
  12. 92
    “…Galleria mellonella larvae have been widely used as alternative non-mammalian models for the study of fungal virulence and pathogenesis. …”
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    Rearing and Maintenance of Galleria mellonella and Its Application to Study Fungal Virulence
  13. 93
    “…The gold standard to assess Candida virulence is the mouse model of systemic candidiasis, a restrictive, expensive, and time-consuming approach; therefore, invertebrate models have been proposed as alternatives. Galleria mellonella larvae have several traits that make them good candidates to study the fungal virulence. …”
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    Early Virulence Predictors during the Candida Species–Galleria mellonella Interaction
  14. 94
    “…The greater wax moth Galleria mellonella is an invertebrate that is increasingly being used in scientific research. …”
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    The greater wax moth Galleria mellonella: biology and use in immune studies
  15. 95
    “…Galleria mellonella larvae are an alternative in vivo model that has been extensively used to study the virulence and pathogenicity of different bacteria due to its practicality and lack of ethical constraints. …”
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    Monitoring Gene Expression during a Galleria mellonella Bacterial Infection
  16. 96
    “…Understanding K. pneumoniae pathogenesis is hampered by the fact that murine models of infection offer limited resolution for non-hypervirulent strains which cause the majority of infections. The insect Galleria mellonella larva is a widely used alternative model organism for bacterial pathogens. …”
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    Identifying virulence determinants of multidrug-resistant Klebsiella pneumoniae in Galleria mellonella
  17. 97
    por Tao, Ye, Duma, Luminita, Rossez, Yannick
    Publicado 2021
    “…The invertebrate model, Galleria mellonella, has been widely used to study host–pathogen interactions due to its cheapness, ease of handling, and similar mammalian innate immune system. …”
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    Galleria mellonella as a Good Model to Study Acinetobacter baumannii Pathogenesis
  18. 98
    “…We present evidence for the therapeutic effect of sulforaphane and phenethyl ITC against a S. dysenteriae infection in the Galleria mellonella larvae model. Thus, our results indicate that isothiocyanates can be effectively used to combat dangerous bacterial infections.…”
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    Evaluation of the Anti-Shigellosis Activity of Dietary Isothiocyanates in Galleria mellonella Larvae
  19. 99
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    Reduced neural investment in post-reproductive females of the bee Ceratina calcarta
  20. 100
    “…Galleria mellonella cationic protein 8 (GmCP8) is a hemolymph protein previously identified as an opsonin and an inhibitor of fungal proteases. …”
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    Cationic protein 8 plays multiple roles in Galleria mellonella immunity
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