Lack of Toxicity in Nonhuman Primates Receiving Clinically Relevant Doses of an AAV9.U7snRNA Vector Designed to Induce DMD Exon 2 Skipping

por Gushchina, Liubov V., Frair, Emma C., Rohan, Natalie, Bradley, Adrienne J., Simmons, Tabatha R., Chavan, Hemantkumar D., Chou, Hsin-Jung, Eggers, Michelle, Waldrop, Megan A., Wein, Nicolas, Flanigan, Kevin M.
Publicado 2021

Archaeal Hel308 suppresses recombination through a catalytic switch that controls DNA annealing

por Lever, Rebecca J, Simmons, Emily, Gamble-Milner, Rebecca, Buckley, Ryan J, Harrison, Catherine, Parkes, Ashley J, Mitchell, Laura, Gausden, Jacob A, Škulj, Sanja, Bertoša, Branimir, Bolt, Edward L, Allers, Thorsten
Publicado 2023

Epidemiological and molecular characterization of a novel adenovirus of squirrel monkeys after fatal infection during immunosuppression

por Rogers, Donna L., Ruiz, Julio C., Baze, Wallace B., McClure, Gloria B., Smith, Carolyn, Urbanowski, Ricky, Boston, Theresa, Simmons, Joe H., Williams, Lawrence, Abee, Christian R., Vanchiere, John A.
Publicado 2020

Dengue Virus in Sub-tropical Northern and Central Viet Nam: Population Immunity and Climate Shape Patterns of Viral Invasion and Maintenance

por Rabaa, Maia A., Simmons, Cameron P., Fox, Annette, Le, Mai Quynh, Nguyen, Thuy Thi Thu, Le, Hai Yen, Gibbons, Robert V., Nguyen, Xuyen Thanh, Holmes, Edward C., Aaskov, John G.
Publicado 2013

Benchmark datasets for phylogenomic pipeline validation, applications for foodborne pathogen surveillance

por Timme, Ruth E., Rand, Hugh, Shumway, Martin, Trees, Eija K., Simmons, Mustafa, Agarwala, Richa, Davis, Steven, Tillman, Glenn E., Defibaugh-Chavez, Stephanie, Carleton, Heather A., Klimke, William A., Katz, Lee S.
Publicado 2017

Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington’s Disease: Preclinical Evidence with the p75(NTR) Ligand LM11A-31

por Simmons, Danielle A., Mills, Brian D., Butler III, Robert R., Kuan, Jason, McHugh, Tyne L. M., Akers, Carolyn, Zhou, James, Syriani, Wassim, Grouban, Maged, Zeineh, Michael, Longo, Frank M.
Publicado 2021

Transcriptome‐wide comparison of selenium hyperaccumulator and nonaccumulator Stanleya species provides new insight into key processes mediating the hyperaccumulation syndrome

por Wang, Jiameng, Cappa, Jennifer J., Harris, Jonathan P., Edger, Patrick P., Zhou, Wen, Pires, J. Chris, Adair, Michael, Unruh, Sarah A., Simmons, Mark P., Schiavon, Michela, Pilon‐Smits, Elizabeth A. H.
Publicado 2018

Evaluative Profiling of Arsenic Sensing and Regulatory Systems in the Human Microbiome Project Genomes

por Isokpehi, Raphael D, Udensi, Udensi K, Simmons, Shaneka S, Hollman, Antoinesha L, Cain, Antia E, Olofinsae, Samson A, Hassan, Oluwabukola A, Kashim, Zainab A, Enejoh, Ojochenemi A, Fasesan, Deborah E, Nashiru, Oyekanmi
Publicado 2014

Bacterial diversity dynamics in microbial consortia selected for lignin utilization

por Mendes, Isis Viana, Garcia, Mariana Botelho, Bitencourt, Ana Carolina Araújo, Santana, Renata Henrique, Lins, Philippe de Castro, Silveira, Rafaella, Simmons, Blake A., Gladden, John M., Kruger, Ricardo Henrique, Quirino, Betania Ferraz
Publicado 2021

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection

por Fitzmaurice, Karen, Petrovic, Danijela, Ramamurthy, Narayan, Simmons, Ruth, Merani, Shazma, Gaudieri, Silvana, Sims, Stuart, Dempsey, Eugene, Freitas, Elizabeth, Lea, Susan, McKiernan, Susan, Norris, Suzanne, Long, Aideen, Kelleher, Dermot, Klenerman, Paul
Publicado 2011

Convection Enhanced Delivery: A Comparison of infusion characteristics in ex vivo and in vivo non-human primate brain tissue

por Miranpuri, Gurwattan, Hinchman, Angelica, Wang, Anyi, Schomberg, Dominic, Kubota, Ken, Brady, Martin, Raghavan, Raghu, Bruner, Kevin, Brodsky, Ethan, Block, Walter, Grabow, Ben, Raschke, Jim, Alexander, Andrew, Ross, Chris, Simmons, Heather, Sillay, Karl
Publicado 2013

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion

por Aulicino, Anna, Antanaviciute, Agne, Frost, Joe, Sousa Geros, Ana, Mellado, Esther, Attar, Moustafa, Jagielowicz, Marta, Hublitz, Philip, Sinz, Julia, Preciado-Llanes, Lorena, Napolitani, Giorgio, Bowden, Rory, Koohy, Hashem, Drakesmith, Hal, Simmons, Alison
Publicado 2022

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

por Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip, Forbes, Josephine M.
Publicado 2017

Bugs and Brains, the Gut and Mental Health Study: a mixed-methods study investigating microbiota composition and function in anxiety, depression and irritable bowel syndrome

por Simpson, Carra A, Schwartz, Orli S, Eliby, Djamila, Butler, Catherine A, Huang, Katherine, O'Brien-Simpson, Neil, Callaghan, Bridget L, Dashper, Stuart G, Gooley, Paul R, Whittle, Sarah, Haslam, Nick, Simmons, Julian G
Publicado 2021

Comparative Genomic Analyses of the Human NPHP1 Locus Reveal Complex Genomic Architecture and Its Regional Evolution in Primates

por Yuan, Bo, Liu, Pengfei, Gupta, Aditya, Beck, Christine R., Tejomurtula, Anusha, Campbell, Ian M., Gambin, Tomasz, Simmons, Alexandra D., Withers, Marjorie A., Harris, R. Alan, Rogers, Jeffrey, Schwartz, David C., Lupski, James R.
Publicado 2015

Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction

por Eaton, Malcolm, Davies, Alastair H., Devine, Jay, Zhao, Xiang, Simmons, David G., Maríusdóttir, Elín, Natale, David R. C., Matyas, John R., Bering, Elizabeth A., Workentine, Matthew L., Hallgrimsson, Benedikt, Cross, James C.
Publicado 2020

High-throughput genetic engineering of nonmodel and undomesticated bacteria via iterative site-specific genome integration

por Elmore, Joshua R., Dexter, Gara N., Baldino, Henri, Huenemann, Jay D., Francis, Ryan, Peabody, George L., Martinez-Baird, Jessica, Riley, Lauren A., Simmons, Tuesday, Coleman-Derr, Devin, Guss, Adam M., Egbert, Robert G.
Publicado 2023

Systemic delivery of an AAV9 exon-skipping vector significantly improves or prevents features of Duchenne muscular dystrophy in the Dup2 mouse

por Wein, Nicolas, Vetter, Tatyana A., Vulin, Adeline, Simmons, Tabatha R., Frair, Emma C., Bradley, Adrienne J., Gushchina, Liubov V., Almeida, Camila F., Huang, Nianyuan, Lesman, Daniel, Rajakumar, Dhanarajan, Weiss, Robert B., Flanigan, Kevin M.
Publicado 2022

Hepatic MDR3 expression impacts lipid homeostasis and susceptibility to inflammatory bile duct obstruction in neonates

por Carey, Alexandra N., Zhang, Wujuan, Setchell, Kenneth D.R., Simmons, Julia E., Shi, Tiffany, Lages, Celine S., Mullen, Mary, Carroll, Kaitlin, Karns, Rebekah, Bessho, Kazuhiko, Sheridan, Rachel, Zhao, Xueheng, Weber, Susanne N., Miethke, Alexander G.
Publicado 2017

The role of positive selection in determining the molecular cause of species differences in disease

por Vamathevan, Jessica J, Hasan, Samiul, Emes, Richard D, Amrine-Madsen, Heather, Rajagopalan, Dilip, Topp, Simon D, Kumar, Vinod, Word, Michael, Simmons, Mark D, Foord, Steven M, Sanseau, Philippe, Yang, Ziheng, Holbrook, Joanna D
Publicado 2008