Clinical Utility of Universal Germline Genetic Testing for Patients With Breast Cancer

por Whitworth, Pat W., Beitsch, Peter D., Patel, Rakesh, Rosen, Barry, Compagnoni, Gia, Baron, Paul L., Simmons, Rache, Brown, Eric A., Gold, Linsey, Holmes, Dennis, Smith, Linda Ann, Kinney, Michael, Grady, Ian, Clark, Patricia, Barbosa, Karen, Lyons, Samuel, Riley, Lee, Coomer, Cynara, Curcio, Lisa, Ruiz, Antonio, Khan, Sadia, MacDonald, Heather, Hughes, Kevin, Hardwick, Mary Kay, Heald, Brandie, Munro, Sandra B., Nielsen, Sarah M., Esplin, Edward D.
Publicado 2022

The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study

por Papuc, Sorina M., Abela, Lucia, Steindl, Katharina, Begemann, Anaïs, Simmons, Thomas L., Schmitt, Bernhard, Zweier, Markus, Oneda, Beatrice, Socher, Eileen, Crowther, Lisa M., Wohlrab, Gabriele, Gogoll, Laura, Poms, Martin, Seiler, Michelle, Papik, Michael, Baldinger, Rosa, Baumer, Alessandra, Asadollahi, Reza, Kroell-Seger, Judith, Schmid, Regula, Iff, Tobias, Schmitt-Mechelke, Thomas, Otten, Karoline, Hackenberg, Annette, Addor, Marie-Claude, Klein, Andrea, Azzarello-Burri, Silvia, Sticht, Heinrich, Joset, Pascal, Plecko, Barbara, Rauch, Anita
Publicado 2018

Distinct subnetworks of the thalamic reticular nucleus

por Li, Yinqing, Lopez-Huerta, Violeta G., Adiconis, Xian, Levandowski, Kirsten, Choi, Soonwook, Simmons, Sean K., Arias-Garcia, Mario A., Guo, Baolin, Yao, Annie Y., Blosser, Timothy R., Wimmer, Ralf D., Aida, Tomomi, Atamian, Alexander, Naik, Tina, Sun, Xuyun, Bi, Dasheng, Malhotra, Diya, Hession, Cynthia C., Shema, Reut, Gomes, Marcos, Li, Taibo, Hwang, Eunjin, Krol, Alexandra, Kowalczyk, Monika, Peça, João, Pan, Gang, Halassa, Michael M., Levin, Joshua Z., Fu, Zhanyan, Feng, Guoping
Publicado 2020

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

por Grubman, Alexandra, Choo, Xin Yi, Chew, Gabriel, Ouyang, John F., Sun, Guizhi, Croft, Nathan P., Rossello, Fernando J., Simmons, Rebecca, Buckberry, Sam, Landin, Dulce Vargas, Pflueger, Jahnvi, Vandekolk, Teresa H., Abay, Zehra, Zhou, Yichen, Liu, Xiaodong, Chen, Joseph, Larcombe, Michael, Haynes, John M., McLean, Catriona, Williams, Sarah, Chai, Siew Yeen, Wilson, Trevor, Lister, Ryan, Pouton, Colin W., Purcell, Anthony W., Rackham, Owen J. L., Petretto, Enrico, Polo, Jose M.
Publicado 2021

Phylogenomically Guided Identification of Industrially Relevant GH1 β-Glucosidases through DNA Synthesis and Nanostructure-Initiator Mass Spectrometry

por Heins, Richard A., Cheng, Xiaoliang, Nath, Sangeeta, Deng, Kai, Bowen, Benjamin P., Chivian, Dylan C., Datta, Supratim, Friedland, Gregory D., D’Haeseleer, Patrik, Wu, Dongying, Tran-Gyamfi, Mary, Scullin, Chessa S., Singh, Seema, Shi, Weibing, Hamilton, Matthew G., Bendall, Matthew L., Sczyrba, Alexander, Thompson, John, Feldman, Taya, Guenther, Joel M., Gladden, John M., Cheng, Jan-Fang, Adams, Paul D., Rubin, Edward M., Simmons, Blake A., Sale, Kenneth L., Northen, Trent R., Deutsch, Samuel
Publicado 2014

A Specialized Epithelial Cell Type Regulating Mucosal Immunity and Driving Human Crohn’s Disease

por Li, Jia, Simmons, Alan J., Chiron, Sophie, Ramirez-Solano, Marisol A., Tasneem, Naila, Kaur, Harsimran, Xu, Yanwen, Revetta, Frank, Vega, Paige N., Bao, Shunxing, Cui, Can, Tyree, Regina N., Raber, Larry W., Conner, Anna N., Beaulieu, Dawn B., Dalal, Robin L., Horst, Sara N., Pabla, Baldeep S., Huo, Yuankai, Landman, Bennett A., Roland, Joseph T., Scoville, Elizabeth A., Schwartz, David A., Washington, M. Kay, Shyr, Yu, Wilson, Keith T., Coburn, Lori A., Lau, Ken S., Liu, Qi
Publicado 2023

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

por Luo, Yang, de Lange, Katrina M., Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A., Lamb, Christopher A., McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Hart, Ailsa, Hawkey, Chris, Mansfield, John C., Mowat, Craig, Newman, William G., Nichols, Sam, Pollard, Martin, Satsangi, Jack, Simmons, Alison, Tremelling, Mark, Uhlig, Holm, Wilson, David C., Lee, James C., Prescott, Natalie J., Lees, Charlie W., Mathew, Christopher G., Parkes, Miles, Barrett, Jeffrey C., Anderson, Carl A.
Publicado 2017

Diploid-dominant life cycles characterize the early evolution of Fungi

por Amses, Kevin R., Simmons, D. Rabern, Longcore, Joyce E., Mondo, Stephen J., Seto, Kensuke, Jerônimo, Gustavo H., Bonds, Anne E., Quandt, C. Alisha, Davis, William J., Chang, Ying, Federici, Brian A., Kuo, Alan, LaButti, Kurt, Pangilinan, Jasmyn, Andreopoulos, William, Tritt, Andrew, Riley, Robert, Hundley, Hope, Johnson, Jenifer, Lipzen, Anna, Barry, Kerrie, Lang, B. Franz, Cuomo, Christina A., Buchler, Nicolas E., Grigoriev, Igor V., Spatafora, Joseph W., Stajich, Jason E., James, Timothy Y.
Publicado 2022

Collagen IV(α345) dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture’s and Alport diseases

por Pokidysheva, Elena N., Seeger, Harald, Pedchenko, Vadim, Chetyrkin, Sergei, Bergmann, Carsten, Abrahamson, Dale, Cui, Zhao Wei, Delpire, Eric, Fervenza, Fernando C., Fidler, Aaron L., Fogo, Agnes B., Gaspert, Ariana, Grohmann, Maik, Gross, Oliver, Haddad, George, Harris, Raymond C., Kashtan, Clifford, Kitching, A. Richard, Lorenzen, Johan M., McAdoo, Stephen, Pusey, Charles D., Segelmark, Marten, Simmons, Alicia, Voziyan, Paul A., Wagner, Timo, Wüthrich, Rudolf P., Zhao, Ming-Hui, Boudko, Sergei P., Kistler, Andreas D., Hudson, Billy G.
Publicado 2021

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

por Blakely, Collin M., Watkins, Thomas B.K., Wu, Wei, Gini, Beatrice, Chabon, Jacob J., McCoach, Caroline E., McGranahan, Nicholas, Wilson, Gareth A., Birkbak, Nicolai J., Olivas, Victor R., Rotow, Julia, Maynard, Ashley, Wang, Victoria, Gubens, Matthew A., Banks, Kimberly C., Lanman, Richard B., Caulin, Aleah F., John, John St., Cordero, Anibal R., Giannikopoulos, Petros, Simmons, Andrew D., Mack, Philip C., Gandara, David R., Husain, Hatim, Doebele, Robert C., Riess, Jonathan W., Diehn, Maximilian, Swanton, Charles, Bivona, Trever G.
Publicado 2017

Genome-wide association study identifies susceptibility loci for Dengue shock syndrome at MICB and PLCE1

por Khor, Chiea Chuen, Bich, Chau Tran Nguyen, Pang, Junxiong, Davila, Sonia, Long, Hoang Truong, Ong, Rick T.H., Dunstan, Sarah J., Wills, Bridget, Farrar, Jeremy, Van Tram, Ta, Gan, Tran Thi, Binh, Nguyen Thi Nguyet, Tri, Le Trung, Lien, Le Bich, Tuan, Nguyen Minh, Tham, Nguyen Thi Hong, Lanh, Mai Ngoc, Nguyet, Nguyen Minh, Hieu, Nguyen Trong, Van Vinh Chau, Nguyen, Thuy, Tran Thi, Tan, Dennis E.K., Sakuntabhai, Anavaj, Teo, Yik-Ying, Hibberd, Martin L, Simmons, Cameron P.
Publicado 2011

Automated next-generation profiling of genomic alterations in human cancers

por Keefer, Laurel A., White, James R., Wood, Derrick E., Gerding, Kelly M. R., Valkenburg, Kenneth C., Riley, David, Gault, Christopher, Papp, Eniko, Vollmer, Christine M., Greer, Amy, Hernandez, James, McGregor, Paul M., Zingone, Adriana, Ryan, Bríd M., Deak, Kristen, McCall, Shannon J., Datto, Michael B., Prescott, James L., Thompson, John F., Cerqueira, Gustavo C., Jones, Siân, Simmons, John K., McElhinny, Abigail, Dickey, Jennifer, Angiuoli, Samuel V., Diaz, Luis A., Velculescu, Victor E., Sausen, Mark
Publicado 2022

Validation of a Circulating Tumor DNA‐Based Next‐Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing

por Al Zoughbi, Wael, Fox, Jesse, Beg, Shaham, Papp, Eniko, Hissong, Erika, Ohara, Kentaro, Keefer, Laurel, Sigouros, Michael, Kane, Troy, Bockelman, Daniel, Nichol, Donna, Patchell, Emily, Bareja, Rohan, Karandikar, Aanavi, Alnajar, Hussein, Cerqueira, Gustavo, Guthrie, Violeta Beleva, Verner, Ellen, Manohar, Jyothi, Greco, Noah, Wilkes, David, Tagawa, Scott, Malbari, Murtaza S., Holcomb, Kevin, Eng, Kenneth Wha, Shah, Manish, Altorki, Nasser K., Sboner, Andrea, Nanus, David, Faltas, Bishoy, Sternberg, Cora N., Simmons, John, Houvras, Yariv, Molina, Ana M., Angiuoli, Samuel, Elemento, Olivier, Mosquera, Juan Miguel
Publicado 2021

A comparative genomics study of 23 Aspergillus species from section Flavi

por Kjærbølling, Inge, Vesth, Tammi, Frisvad, Jens C., Nybo, Jane L., Theobald, Sebastian, Kildgaard, Sara, Petersen, Thomas Isbrandt, Kuo, Alan, Sato, Atsushi, Lyhne, Ellen K., Kogle, Martin E., Wiebenga, Ad, Kun, Roland S., Lubbers, Ronnie J. M., Mäkelä, Miia R., Barry, Kerrie, Chovatia, Mansi, Clum, Alicia, Daum, Chris, Haridas, Sajeet, He, Guifen, LaButti, Kurt, Lipzen, Anna, Mondo, Stephen, Pangilinan, Jasmyn, Riley, Robert, Salamov, Asaf, Simmons, Blake A., Magnuson, Jon K., Henrissat, Bernard, Mortensen, Uffe H., Larsen, Thomas O., de Vries, Ronald P., Grigoriev, Igor V., Machida, Masayuki, Baker, Scott E., Andersen, Mikael R.
Publicado 2020

A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer’s Disease

por Khan, Wasim, Giampietro, Vincent, Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L.W., Büchel, Christian, Conrod, Patricia, Flor, Herta, Frouin, Vincent, Garavan, Hugh, Gowland, Penny, Heinz, Anreas, Ittermann, Bernd, Lemaître, Hervé, Nees, Frauke, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Smolka, Michael N., Ströhle, Andreas, Gallinat, Jeurgen, Vellas, Bruno, Soininen, Hilkka, Kloszewska, Iwona, Tsolaki, Magda, Mecocci, Patrizia, Spenger, Christian, Villemagne, Victor L., Masters, Colin L., Muehlboeck, J-Sebastian, Bäckman, Lars, Fratiglioni, Laura, Kalpouzos, Grégoria, Wahlund, Lars-Olof, Schumann, Gunther, Lovestone, Simon, Williams, Steven C.R., Westman, Eric, Simmons, Andrew
Publicado 2017

Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade

por Yam-Puc, Juan Carlos, Hosseini, Zhaleh, Horner, Emily C., Gerber, Pehuén Pereyra, Beristain-Covarrubias, Nonantzin, Hughes, Robert, Lulla, Aleksei, Rust, Maria, Boston, Rebecca, Ali, Magda, Fischer, Katrin, Simmons-Rosello, Edward, O’Reilly, Martin, Robson, Harry, Booth, Lucy H., Kahanawita, Lakmini, Correa-Noguera, Andrea, Favara, David, Ceron-Gutierrez, Lourdes, Keller, Baerbel, Craxton, Andrew, Anderson, Georgina S. F., Sun, Xiao-Ming, Elmer, Anne, Saunders, Caroline, Bermperi, Areti, Jose, Sherly, Kingston, Nathalie, Mulroney, Thomas E., Piñon, Lucia P. G., Chapman, Michael A., Grigoriadou, Sofia, MacFarlane, Marion, Willis, Anne E., Patil, Kiran R., Spencer, Sarah, Staples, Emily, Warnatz, Klaus, Buckland, Matthew S., Hollfelder, Florian, Hyvönen, Marko, Döffinger, Rainer, Parkinson, Christine, Lear, Sara, Matheson, Nicholas J., Thaventhiran, James E. D.
Publicado 2023

Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission

por Karthikeyan, Smruthi, Levy, Joshua I, De Hoff, Peter, Humphrey, Greg, Birmingham, Amanda, Jepsen, Kristen, Farmer, Sawyer, Tubb, Helena M., Valles, Tommy, Tribelhorn, Caitlin E, Tsai, Rebecca, Aigner, Stefan, Sathe, Shashank, Moshiri, Niema, Henson, Benjamin, Mark, Adam M., Hakim, Abbas, Baer, Nathan A, Barber, Tom, Belda-Ferre, Pedro, Chacón, Marisol, Cheung, Willi, Cresini, Evelyn S, Eisner, Emily R, Lastrella, Alma L, Lawrence, Elijah S, Marotz, Clarisse A, Ngo, Toan T, Ostrander, Tyler, Plascencia, Ashley, Salido, Rodolfo A, Seaver, Phoebe, Smoot, Elizabeth W, McDonald, Daniel, Neuhard, Robert M, Scioscia, Angela L, Satterlund, Alysson M., Simmons, Elizabeth H, Abelman, Dismas B., Brenner, David, Bruner, Judith C., Buckley, Anne, Ellison, Michael, Gattas, Jeffrey, Gonias, Steven L., Hale, Matt, Hawkins, Faith, Ikeda, Lydia, Jhaveri, Hemlata, Johnson, Ted, Kellen, Vince, Kremer, Brendan, Matthews, Gary, McLawhon, Ronald W., Ouillet, Pierre, Park, Daniel, Pradenas, Allorah, Reed, Sharon, Riggs, Lindsay, Sanders, Alison, Sollenberger, Bradley, Song, Angela, White, Benjamin, Winbush, Terri, Aceves, Christine M, Anderson, Catelyn, Gangavarapu, Karthik, Hufbauer, Emory, Kurzban, Ezra, Lee, Justin, Matteson, Nathaniel L, Parker, Edyth, Perkins, Sarah A, Ramesh, Karthik S, Robles-Sikisaka, Refugio, Schwab, Madison A, Spencer, Emily, Wohl, Shirlee, Nicholson, Laura, Mchardy, Ian H, Dimmock, David P, Hobbs, Charlotte A, Bakhtar, Omid, Harding, Aaron, Mendoza, Art, Bolze, Alexandre, Becker, David, Cirulli, Elizabeth T, Isaksson, Magnus, Barrett, Kelly M Schiabor, Washington, Nicole L, Malone, John D, Schafer, Ashleigh Murphy, Gurfield, Nikos, Stous, Sarah, Fielding-Miller, Rebecca, Garfein, Richard S., Gaines, Tommi, Anderson, Cheryl, Martin, Natasha K., Schooley, Robert, Austin, Brett, MacCannell, Duncan R., Kingsmore, Stephen F, Lee, William, Shah, Seema, McDonald, Eric, Yu, Alexander T., Zeller, Mark, Fisch, Kathleen M, Longhurst, Christopher, Maysent, Patty, Pride, David, Khosla, Pradeep K., Laurent, Louise C., Yeo, Gene W, Andersen, Kristian G, Knight, Rob
Publicado 2022

Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

por Karthikeyan, Smruthi, Levy, Joshua I., De Hoff, Peter, Humphrey, Greg, Birmingham, Amanda, Jepsen, Kristen, Farmer, Sawyer, Tubb, Helena M., Valles, Tommy, Tribelhorn, Caitlin E., Tsai, Rebecca, Aigner, Stefan, Sathe, Shashank, Moshiri, Niema, Henson, Benjamin, Mark, Adam M., Hakim, Abbas, Baer, Nathan A., Barber, Tom, Belda-Ferre, Pedro, Chacón, Marisol, Cheung, Willi, Cresini, Evelyn S., Eisner, Emily R., Lastrella, Alma L., Lawrence, Elijah S., Marotz, Clarisse A., Ngo, Toan T., Ostrander, Tyler, Plascencia, Ashley, Salido, Rodolfo A., Seaver, Phoebe, Smoot, Elizabeth W., McDonald, Daniel, Neuhard, Robert M., Scioscia, Angela L., Satterlund, Alysson M., Simmons, Elizabeth H., Abelman, Dismas B., Brenner, David, Bruner, Judith C., Buckley, Anne, Ellison, Michael, Gattas, Jeffrey, Gonias, Steven L., Hale, Matt, Hawkins, Faith, Ikeda, Lydia, Jhaveri, Hemlata, Johnson, Ted, Kellen, Vince, Kremer, Brendan, Matthews, Gary, McLawhon, Ronald W., Ouillet, Pierre, Park, Daniel, Pradenas, Allorah, Reed, Sharon, Riggs, Lindsay, Sanders, Alison, Sollenberger, Bradley, Song, Angela, White, Benjamin, Winbush, Terri, Aceves, Christine M., Anderson, Catelyn, Gangavarapu, Karthik, Hufbauer, Emory, Kurzban, Ezra, Lee, Justin, Matteson, Nathaniel L., Parker, Edyth, Perkins, Sarah A., Ramesh, Karthik S., Robles-Sikisaka, Refugio, Schwab, Madison A., Spencer, Emily, Wohl, Shirlee, Nicholson, Laura, McHardy, Ian H., Dimmock, David P., Hobbs, Charlotte A., Bakhtar, Omid, Harding, Aaron, Mendoza, Art, Bolze, Alexandre, Becker, David, Cirulli, Elizabeth T., Isaksson, Magnus, Schiabor Barrett, Kelly M., Washington, Nicole L., Malone, John D., Schafer, Ashleigh Murphy, Gurfield, Nikos, Stous, Sarah, Fielding-Miller, Rebecca, Garfein, Richard S., Gaines, Tommi, Anderson, Cheryl, Martin, Natasha K., Schooley, Robert, Austin, Brett, MacCannell, Duncan R., Kingsmore, Stephen F., Lee, William, Shah, Seema, McDonald, Eric, Yu, Alexander T., Zeller, Mark, Fisch, Kathleen M., Longhurst, Christopher, Maysent, Patty, Pride, David, Khosla, Pradeep K., Laurent, Louise C., Yeo, Gene W., Andersen, Kristian G., Knight, Rob
Publicado 2022

Surveillance of Vermont wildlife in 2021–2022 reveals no detected SARS-CoV-2 viral RNA

por Despres, Hannah W., Mills, Margaret G., Schmidt, Madaline M., Gov, Jolene, Perez, Yael, Jindrich, Mars, Crawford, Allison M. L., Kohl, Warren T., Rosenblatt, Elias, Kubinski, Hannah C., Simmons, Benjamin C., Nippes, Miles C., Goldenberg, Anne J., Murtha, Kristina E., Nicoloro, Samantha, Harris, Mia J., Feeley, Avery C., Gelinas, Taylor K., Cronin, Maeve K., Frederick, Robert S., Thomas, Matthew, Johnson, Meaghan E., Murphy, James, Lenzini, Elle B., Carr, Peter A., Berger, Danielle H., Mehta, Soham P., Floreani, Christopher J., Koval, Amelia C., Young, Aleah L., Fish, Jess H., Wallace, Jack, Chaney, Ella, Ushay, Grace, Ross, Rebecca S., Vostal, Erin M., Thisner, Maya C., Gonet, Kyliegh E., Deane, Owen C., Pelletiere, Kari R., Rockafeller, Vegas C., Waterman, Madeline, Barry, Tyler W., Goering, Catriona C., Shipman, Sarah D., Shiers, Allie C., Reilly, Claire E., Duff, Alanna M., Madruga, Sarah L., Shirley, David J., Jerome, Keith R., Pérez-Osorio, Ailyn C., Greninger, Alexander L., Fortin, Nick, Mosher, Brittany A., Bruce, Emily A.
Publicado 2023

Surveillance of Vermont wildlife in 2021–2022 reveals no detected SARS-CoV-2 viral RNA

por Despres, Hannah W., Mills, Margaret G., Schmidt, Madaline M., Gov, Jolene, Perez, Yael, Jindrich, Mars, Crawford, Allison M. L., Kohl, Warren T., Rosenblatt, Elias, Kubinski, Hannah C., Simmons, Benjamin C., Nippes, Miles C., Goldenberg, Anne J., Murtha, Kristina E., Nicoloro, Samantha, Harris, Mia J., Feeley, Avery C., Gelinas, Taylor K., Cronin, Maeve K., Frederick, Robert S., Thomas, Matthew, Johnson, Meaghan E., Murphy, James, Lenzini, Elle B., Carr, Peter A., Berger, Danielle H., Mehta, Soham P., Floreani, Christopher J., Koval, Amelia C., Young, Aleah L., Fish, Jess H., Wallace, Jack, Chaney, Ella, Ushay, Grace, Ross, Rebecca S., Vostal, Erin M., Thisner, Maya C., Gonet, Kyliegh E., Deane, Owen C., Pelletiere, Kari R., Rockafeller, Vegas C., Waterman, Madeline, Barry, Tyler W., Goering, Catriona C., Shipman, Sarah D., Shiers, Allie C., Reilly, Claire E., Duff, Alanna M., Shirley, David J., Jerome, Keith R., Pérez-Osorio, Ailyn C., Greninger, Alexander L., Fortin, Nick, Mosher, Brittany A., Bruce, Emily A.
Publicado 2023