Whole exome sequencing in childhood-onset lupus frequently detects single gene etiologies

por Tirosh, Irit, Spielman, Shiri, Barel, Ortal, Ram, Reut, Stauber, Tali, Paret, Gideon, Rubinsthein, Marina, Pessach, Itai M., Gerstein, Maya, Anikster, Yair, Shukrun, Rachel, Dagan, Adi, Adler, Katerina, Pode-Shakked, Ben, Volkov, Alexander, Perelman, Marina, Greenberger, Shoshana, Somech, Raz, Lahav, Einat, Majmundar, Amar J., Padeh, Shai, Hildebrandt, Friedhelm, Vivante, Asaf
Publicado 2019

Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials

por Goldman, Jennifer G., Forsberg, Leah K., Boeve, Bradley F., Armstrong, Melissa J., Irwin, David J., Ferman, Tanis J., Galasko, Doug, Galvin, James E., Kaufer, Daniel, Leverenz, James, Lippa, Carol F., Marder, Karen, Abler, Victor, Biglan, Kevin, Irizarry, Michael, Keller, Bill, Munsie, Leanne, Nakagawa, Masaki, Taylor, Angela, Graham, Todd
Publicado 2020

The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance

por Kimura, Izumi, Kosugi, Yusuke, Wu, Jiaqi, Zahradnik, Jiri, Yamasoba, Daichi, Butlertanaka, Erika P., Tanaka, Yuri L., Uriu, Keiya, Liu, Yafei, Morizako, Nanami, Shirakawa, Kotaro, Kazuma, Yasuhiro, Nomura, Ryosuke, Horisawa, Yoshihito, Tokunaga, Kenzo, Ueno, Takamasa, Takaori-Kondo, Akifumi, Schreiber, Gideon, Arase, Hisashi, Motozono, Chihiro, Saito, Akatsuki, Nakagawa, So, Sato, Kei
Publicado 2022

DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

por Shen, Xueyi, Caramaschi, Doretta, Adams, Mark J., Walker, Rosie M., Min, Josine L., Kwong, Alex, Hemani, Gibran, Barbu, Miruna C., Whalley, Heather C., Harris, Sarah E., Deary, Ian J., Morris, Stewart W., Cox, Simon R., Relton, Caroline L., Marioni, Riccardo E., Evans, Kathryn L., McIntosh, Andrew M.
Publicado 2022

The human liver microenvironment shapes the homing and function of CD4(+) T-cell populations

por Wiggins, Benjamin G, Pallett, Laura J, Li, Xiaoyan, Davies, Scott P, Amin, Oliver E, Gill, Upkar S, Kucykowicz, Stephanie, Patel, Arzoo M, Aliazis, Konstantinos, Liu, Yuxin S, Reynolds, Gary M, Davidson, Brian R, Gander, Amir, Luong, Tu Vinh, Hirschfield, Gideon M, Kennedy, Patrick T F, Huang, Yuehua, Maini, Mala K, Stamataki, Zania
Publicado 2022

Longitudinal SARS-CoV-2 Nucleocapsid Antibody Kinetics, Seroreversion, and Implications for Seroepidemiologic Studies

por Loesche, Michael, Karlson, Elizabeth W., Talabi, Opeyemi, Zhou, Guohai, Boutin, Natalie, Atchley, Rachel, Loevinsohn, Gideon, Chang, Jun Bai Park, Hasdianda, Mohammad A., Okenla, Adetoun, Sampson, Elizabeth, Schram, Haley, Magsipoc, Karen, Goodman, Kirsten, Donahue, Lauren, MacGowan, Maureen, Novack, Lewis A., Jarolim, Petr, Baden, Lindsey R., Nilles, Eric J.
Publicado 2022

The Global Jukebox: A public database of performing arts and culture

por Wood, Anna L. C., Kirby, Kathryn R., Ember, Carol R., Silbert, Stella, Passmore, Sam, Daikoku, Hideo, McBride, John, Paulay, Forrestine, Flory, Michael J., Szinger, John, D’Arcangelo, Gideon, Bradley, Karen Kohn, Guarino, Marco, Atayeva, Maisa, Rifkin, Jesse, Baron, Violet, El Hajli, Miriam, Szinger, Martin, Savage, Patrick E.
Publicado 2022

Platelet-instructed SPP1(+) macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner

por Hoeft, Konrad, Schaefer, Gideon J.L., Kim, Hyojin, Schumacher, David, Bleckwehl, Tore, Long, Qingqing, Klinkhammer, Barbara Mara, Peisker, Fabian, Koch, Lars, Nagai, James, Halder, Maurice, Ziegler, Susanne, Liehn, Elisa, Kuppe, Christoph, Kranz, Jennifer, Menzel, Sylvia, Costa, Ivan, Wahida, Adam, Boor, Peter, Schneider, Rebekka K., Hayat, Sikander, Kramann, Rafael
Publicado 2023

Diabetic Retinopathy Screening at the Point of Care (DR SPOC): detecting undiagnosed and vision-threatening retinopathy by integrating portable technologies within existing service...

por Weerasinghe, Lakni Shahanika, Dunn, Hamish Paul, Fung, Adrian T, Maberly, Glen, Cheung, Ngai Wah, Weerasinghe, Daminda P, Liew, Gerald, Do, Helen, Hng, Tien-Ming, Pryke, Alison, Marks, Samuel I, Nguyen, Helen, Jayaballa, Rajini, Gurung, Seema, Ford, Belinda, Bishay, Ramy H, Girgis, Christian M, Meyerowitz-Katz, Gideon, Keay, Lisa, White, Andrew J
Publicado 2023

Utilization of digital tools to enhance COVID-19 and tuberculosis testing and linkage to care: A cross-sectional evaluation study among Bodaboda motorbike riders in the Nairobi Met...

por Karanja, Simon, Aduda, Jane, Thuo, Reuben, Wamunyokoli, Fred, Oyier, Philip, Kikuvi, Gideon, Kissinger, Henry, Gachohi, John, Mburugu, Patrick, Kamau, David, Matheri, Joseph, Mwelu, Susan, Machua, Joseph, Amoth, Patrick, Mariga, Denver, Were, Ian, Mohamed, Musa, Kimuyu, Judith, Saigilu, Samson, Wangeci, Rose, Mubadi, Kevin, Ndung’u, Joseph, Suleiman, Khairunisa, Kadam, Rigveda, Akugizibwe, Paula
Publicado 2023

Non-O ABO blood group genotypes differ in their associations with Plasmodium falciparum rosetting and severe malaria

por Opi, D. Herbert, Ndila, Carolyne M., Uyoga, Sophie, Macharia, Alex W., Fennell, Clare, Ochola, Lucy B., Nyutu, Gideon, Siddondo, Bethseba R., Ojal, John, Shebe, Mohammed, Awuondo, Kennedy O., Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Band, Gavin, Maitland, Kathryn, Kwiatkowski, Dominic P., Rockett, Kirk A., Williams, Thomas N., Rowe, J. Alexandra
Publicado 2023

The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions

por Montanier, Cedric, Money, Victoria A, Pires, Virginia M. R, Flint, James E, Pinheiro, Benedita A, Goyal, Arun, Prates, José A. M, Izumi, Atsushi, Stålbrand, Henrik, Morland, Carl, Cartmell, Alan, Kolenova, Katarina, Topakas, Evangelos, Dodson, Eleanor J, Bolam, David N, Davies, Gideon J, Fontes, Carlos M. G. A, Gilbert, Harry J
Publicado 2009

Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

por Lo Leggio, Leila, Simmons, Thomas J., Poulsen, Jens-Christian N., Frandsen, Kristian E. H., Hemsworth, Glyn R., Stringer, Mary A., von Freiesleben, Pernille, Tovborg, Morten, Johansen, Katja S., De Maria, Leonardo, Harris, Paul V., Soong, Chee-Leong, Dupree, Paul, Tryfona, Theodora, Lenfant, Nicolas, Henrissat, Bernard, Davies, Gideon J., Walton, Paul H.
Publicado 2015

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation...

por Zheng, Jie, Erzurumluoglu, A Mesut, Elsworth, Benjamin L, Kemp, John P, Howe, Laurence, Haycock, Philip C, Hemani, Gibran, Tansey, Katherine, Laurin, Charles, Pourcain, Beate St, Warrington, Nicole M, Finucane, Hilary K, Price, Alkes L, Bulik-Sullivan, Brendan K, Anttila, Verneri, Paternoster, Lavinia, Gaunt, Tom R, Evans, David M, Neale, Benjamin M
Publicado 2017

An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion

por Sabbadin, Federico, Hemsworth, Glyn R., Ciano, Luisa, Henrissat, Bernard, Dupree, Paul, Tryfona, Theodora, Marques, Rita D. S., Sweeney, Sean T., Besser, Katrin, Elias, Luisa, Pesante, Giovanna, Li, Yi, Dowle, Adam A., Bates, Rachel, Gomez, Leonardo D., Simister, Rachael, Davies, Gideon J., Walton, Paul H., Bruce, Neil C., McQueen-Mason, Simon J.
Publicado 2018

Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replica...

por Nganou-Makamdop, Krystelle, Billingsley, James M., Yaffe, Zachary, O’Connor, Gregory, Tharp, Gregory K., Ransier, Amy, Laboune, Farida, Matus-Nicodemos, Rodrigo, Lerner, Andrea, Gharu, Lavina, Robertson, Jennifer M., Ford, Mandy L., Schlapschy, Martin, Kuhn, Nadine, Lensch, Alexandra, Lifson, Jeffrey, Nason, Martha, Skerra, Arne, Schreiber, Gideon, Bosinger, Steven E., Douek, Daniel C.
Publicado 2018

Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy

por Ross, Jacob A., Levy, Yotam, Ripolone, Michela, Kolb, Justin S., Turmaine, Mark, Holt, Mark, Lindqvist, Johan, Claeys, Kristl G., Weis, Joachim, Monforte, Mauro, Tasca, Giorgio, Moggio, Maurizio, Figeac, Nicolas, Zammit, Peter S., Jungbluth, Heinz, Fiorillo, Chiara, Vissing, John, Witting, Nanna, Granzier, Henk, Zanoteli, Edmar, Hardeman, Edna C., Wallgren-Pettersson, Carina, Ochala, Julien
Publicado 2019

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

por Spangenberg, Elizabeth, Severson, Paul L., Hohsfield, Lindsay A., Crapser, Joshua, Zhang, Jiazhong, Burton, Elizabeth A., Zhang, Ying, Spevak, Wayne, Lin, Jack, Phan, Nicole Y., Habets, Gaston, Rymar, Andrey, Tsang, Garson, Walters, Jason, Nespi, Marika, Singh, Parmveer, Broome, Stephanie, Ibrahim, Prabha, Zhang, Chao, Bollag, Gideon, West, Brian L., Green, Kim N.
Publicado 2019

Efficacy of rituximab in difficult-to-manage autoimmune hepatitis: Results from the International Autoimmune Hepatitis Group

por Than, Nwe Ni, Hodson, James, Schmidt-Martin, Daniel, Taubert, Richard, Wawman, Rebecca E., Botter, Meemee, Gautam, Nishant, Bock, Kilian, Jones, Rebecca, Appanna, Gautham D, Godkin, Andrew, Montano-Loza, Aldo J., Lammert, Frank, Schramm, Christoph, Manns, Michael P., Swain, Mark, Burak, Kelly W., Adams, David H., Hirschfield, Gideon M, Oo, Ye Htun
Publicado 2019

Emotional and behavioral problems in children with dilated cardiomyopathy

por van der Mheen, Malindi, van der Meulen, Marijke H, den Boer, Susanna L, Schreutelkamp, Dayenne J, van der Ende, Jan, de Nijs, Pieter FA, Breur, Johannes MPJ, Tanke, Ronald B, Blom, Nico A, Rammeloo, Lukas AJ, ten Harkel, Arend DJ, du Marchie Sarvaas, Gideon J, Utens, Elisabeth MWJ, Dalinghaus, Michiel
Publicado 2019