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  1. 601
    “…PURPOSE: This in vitro study was designed to determine the effect of the pan-Janus kinase inhibitor, Tofacitinib, on basal and interleukin-6 (IL-6)-induced signal transducers and activators of transcription (STAT) phosphorylation and matrix metalloproteinase (MMP) gene expression and MMP production by C28/I2 human chondrocytes. METHODS: C28/I2 chondrocytes were grown to a confluent high-density and treated either with recombinant human IL-6 (rhIL-6; 10–20ng/mL) or maintained in the basal state for up to 60 min. …”
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    Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes
  2. 602
    “…RESULTS: Keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) accumulated in the culture supernatant when Trichoderma reesei Δlga1 and Aspergillus niger ΔgaaC were grown in the presence of D-galacturonate. …”
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    Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi
  3. 603
    “…Nearly half of the students (48.0%) specified that a rural clerkship 4 weeks and longer was ‘absolutely imaginable’. Younger age, having grown up in a rural or small-town region, being able to imagine future working in a small-town or rural area, and general practice as favoured, or at least conceivable career option were independently associated with a higher willingness to complete longer rural clerkships. …”
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    How to increase the attractiveness of undergraduate rural clerkships? A cross-sectional study among medical students at two German medical schools
  4. 604
    “…CONCLUSIONS: Our dual transcriptomic analysis supports earlier observations of a marked difference in life style between A. fumigatus and A. niger when grown in the presence of type II epithelial cells. …”
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    Expression profile analysis reveals that Aspergillus fumigatus but not Aspergillus niger makes type II epithelial lung cells less immunological alert
  5. 605
    “…Proteomic analyses supported the up-regulation of several genes belonging to PUL 43 and showed the important over-production of a CBM4-containing GH10 endo-xylanase. …”
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    Xylan degradation by the human gut Bacteroides xylanisolvens XB1A(T) involves two distinct gene clusters that are linked at the transcriptional level
  6. 606
    “…Wheat cultivars ‘TAM 111’ and ‘TAM 112’ have been dominantly grown in the Southern U.S. Great Plains for many years due to their high yield and drought tolerance. …”
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    RNA-seq analysis reveals different drought tolerance mechanisms in two broadly adapted wheat cultivars ‘TAM 111’ and ‘TAM 112’
  7. 607
    “…RESULTS AND DISCUSSION: Co-culturing of LDB B-30892 with C. difficile inhibited the C. difficile-mediated cytotoxicity on Caco-2 cells. When CFS from LDB B-30892-C. difficile co-culture was administered (up to a dilution of 1:16) on Caco-2 monolayer, there were no signs of cytotoxicity. …”
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    Lactobacillus delbrueckii ssp. bulgaricus B-30892 can inhibit cytotoxic effects and adhesion of pathogenic Clostridium difficile to Caco-2 cells
  8. 608
    “…This led us to determine that consumers prefer to detect the characteristic basil flavor made up of 1,8 cineole, eugenol, and linalool, which was not as prevalent in basil grown under 100 μmol ⋅ m(–2) ⋅ s(–1), but too high in basil grown under 400 and 600 μmol ⋅ m(–2) ⋅ s(–1), which led to lower consumer preference.…”
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    Leveraging Controlled-Environment Agriculture to Increase Key Basil Terpenoid and Phenylpropanoid Concentrations: The Effects of Radiation Intensity and CO(2) Concentration on Consumer Preference
  9. 609
    “…Quantitative RT-PCR analyses of sugar-responsive genes revealed that plastidial HXK (pHXK) was up-regulated in adg1-1/tpt-2 plants grown on sugars, but showed no response in adg1-1/tpt-2/gin2-1. …”
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    The Mysterious Rescue of adg1-1/tpt-2 – an Arabidopsis thaliana Double Mutant Impaired in Acclimation to High Light – by Exogenously Supplied Sugars
  10. 610
    “…Human proximal tubular cells (HK-2 cells) were grown in serum-free medium enriched with pooled urines from Decliners or Non-decliners. …”
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    Transcriptome Analysis of Proximal Tubular Cells (HK-2) Exposed to Urines of Type 1 Diabetes Patients at Risk of Early Progressive Renal Function Decline
  11. 611
    “…The aim is to investigate the potential of learning algorithms to classify GC-MS data to be either from conventionally grown or from organically grown samples and considering different cultivars. …”
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    Learning to Classify Organic and Conventional Wheat – A Machine Learning Driven Approach Using the MeltDB 2.0 Metabolomics Analysis Platform
  12. 612
    “…Confocal microscopy revealed that E-cadherin was similarly expressed at the cell boundaries on the plasma membrane of PCa cells grown in 2D-monolayers, as well as in 3D-spheroids, but resulted up-regulated in 3D-spheroids, compared to 2D-monolayers, at the mRNA and protein level. …”
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    Epithelial-To-Mesenchymal Transition Markers and CD44 Isoforms Are Differently Expressed in 2D and 3D Cell Cultures of Prostate Cancer Cells
  13. 613
    “…Crystals were obtained by the hanging-drop vapour-diffusion method at 277 K in a number of screening conditions. Crystals measuring up to 1.5 mm in their longest dimension were grown from solutions containing polyethylene glycol 20 000. …”
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    Expression, purification and crystallization of 2-­oxo-hept-4-ene-1,7-dioate hydratase (HpcG) from Escherichia coli C
  14. 614
    “…Three new enantiopure aryl-thioureas have been synthesized, N-(4-X-phenyl)-N-[1(S)-1-phenylethyl]thiourea, X= Cl, Br, and NO(2) (compounds 1-3, respectively). Large single crystals of up to 0.5 cm(3) were grown from methanol/ethanol solutions. …”
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    Structure, Morphology and Optical Properties of Chiral N-(4-X-phenyl)-N-[1(S)-1-phenylethyl]thiourea, X= Cl, Br, and NO(2)
  15. 615
    “…[Image: see text] A novel metal organic framework (MOF)-based composite was synthesized on a Cu substrate via a two-step route. An amorphous iron oxide/hydroxide layer was first deposited on a Cu foil through a sol–gel process; then, Fe-NH(2)-Mil-101 was grown using both the iron oxide/hydroxide matrix, which provided the Fe(3+) centers needed for MOF formation, and 2-aminoterephthalic acid ethanol solution. …”
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    New Synthetic Route for the Growth of α-FeOOH/NH(2)-Mil-101 Films on Copper Foil for High Surface Area Electrodes
  16. 616
    “…In cuprates, T(C) depends strongly on the out-of-plane Cu-apical oxygen distance and the in-plane Cu-O distance, but there has been little attention paid to tuning them independently. Here, in simply grown, self-assembled, vertically aligned nanocomposite thin films of La(2)CuO(4+δ) + LaCuO(3), by strongly increasing out-of-plane distances without reducing in-plane distances (three-dimensional strain engineering), we achieve superconductivity up to 50 K in the vertical interface regions, spaced ~50 nm apart. …”
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    3D strain-induced superconductivity in La(2)CuO(4+δ) using a simple vertically aligned nanocomposite approach
  17. 617
    “…Instead of conventional temperature ramp-up process, H(2)/NH(3) gas mixture was introduced during the interruption after the growth of InGaN well layers. …”
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    The Atomic Rearrangement of GaN-Based Multiple Quantum Wells in H(2)/NH(3) Mixed Gas for Improving Structural and Optical Properties
  18. 618
    “…Cu(2)O/CuO nanosheets in-situ grown on Cu-Carbon cloths (Cu-CCs), namely Cu(2)O/CuO@Cu-CCs, are constructed by a simple strategy with electroless copper plating, chemical etching, and thermal dehydration. …”
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    In situ Growth of Cu(2)O/CuO Nanosheets on Cu Coating Carbon Cloths as a Binder-Free Electrode for Asymmetric Supercapacitors
  19. 619
    “…Of the VISes, 1153 are detected in the exons or introns of genes, with 294 located up to 5 kb and a further 112 located up to 10 kb away. …”
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    Dr.VIS v2.0: an updated database of human disease-related viral integration sites in the era of high-throughput deep sequencing
  20. 620
    “…The outstanding HER performances of the MoC–Mo(2)C electrode with low overpotentials at 500 mA cm(−2) in both acidic (256 mV) and alkaline electrolytes (292 mV), long-lasting lifetime of over 2400 h (100 d), and high-temperature performance (70 (o)C) are due to the self-standing hydrophilic porous surface, intrinsic mechanical strength and self-grown MoC (001)–Mo(2)C (101) heterojunctions that have a ΔG(H*) value of −0.13 eV in acidic condition, and the energy barrier of 1.15 eV for water dissociation in alkaline solution. …”
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    A durable and pH-universal self-standing MoC–Mo(2)C heterojunction electrode for efficient hydrogen evolution reaction
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