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1821por Karnwal, Arun“…This study aimed to culture and screen salt-tolerant Plant growth promoting rhizobacteria (PGPRs) from Bougainvillea glabra rhizosphere to improve wheat HD-2687 and maize PSCL-4642 cultivars under saline conditions up to the seedling stage. …”
Publicado 2022
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1822“…We first generated transgenic (Tg; nestin/KOr Tg) mice in which production of the fluorescent protein Kusabira-Orange (KOr) is controlled by the gene regulatory elements within the 2nd intronic enhancer of the nestin gene, which is a good marker for NSCs, so that NSCs would emit orange fluorescence upon excitation. …”
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1823por Singbrant, Sofie, Mattebo, Alexander, Sigvardsson, Mikael, Strid, Tobias, Flygare, Johan“…By transplanting purified stress-progenitors expressing the fluorescent protein Kusabira Orange, we determined their kinetics in vivo and demonstrated that CD150+CD9+Sca1– stress-BFU-E provide a massive but transient radioprotective erythroid wave, followed by multi-lineage reconstitution from CD150+CD9+Sca1+ multi-potent stem/progenitor cells. …”
Publicado 2020
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1824“…We also observed a significant difference at the genotype as well as allele frequencies of GABRA1c.IVS11 + 15 A > G polymorphism in drug-resistant patients for homozygous GG genotype (P = 0.03, OR = 1.84, 95% CI = 1.05–3.23) and G allele (P = 0.02, OR = 1.43, 95% CI = 1.05–1.95). …”
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1825por Ibeagha-Awemu, Eveline M., Bissonnette, Nathalie, Bhattarai, Suraj, Wang, Mengqi, Dudemaine, Pier-Luc, McKay, Stephanie, Zhao, Xin“…DMR genes with hypermethylated promoters/5′UTR [3 (IL) and 88 (ILLN)] or hypomethylated promoters/5′UTR [10 (IL) and 25 (ILLN)] and having multiple functions including response to stimulus/immune response (BLK, BTC, CCL21, AVPR1A, CHRNG, GABRA4, TDGF1), cellular processes (H2AC20, TEX101, GLA, NCKAP5L, RBM27, SLC18A1, H2AC20BARHL2, NLGN3, SUV39H1, GABRA4, PPA1, UBE2D2) and metabolic processes (GSTO2, H2AC20, SUV39H1, PPA1, UBE2D2) are potential DNA methylation candidate genes of MAP infection. …”
Publicado 2021
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1826por Borraz-Martínez, Sergio, Simó, Joan, Gras, Anna, Mestre, Mariàngela, Boqué, Ricard“…Fresh and dried-powdered leaves of six different varieties of almond trees of commercial interest (Avijor, Guara, Isabelona, Marta, Pentacebas and Soleta) were used. …”
Publicado 2019
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1827por Kallurkar, Prajkta S., Picardo, Maria Cristina D., Sugimura, Yae K., Saha, Margaret S., Conradi Smith, Gregory D., Del Negro, Christopher A.“…We sequenced Type-1 and Type-2 transcriptomes and identified differential expression of 123 genes including ionotropic receptors (Gria3, Gabra1) that may explain their preinspiratory activation profiles and Ca(2+) signaling (Cracr2a, Sgk1) involved in inspiratory and sigh bursts. …”
Publicado 2022
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1828“…Mutations in GABRs, especially in GABRA1, GABRB2, GABRB3, and GABRG2, impair GABAergic signaling and are frequently associated with DEEs such as Dravet syndrome and Lennox–Gastaut syndrome, as GABAergic signaling is critical for early brain development. …”
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1829“…In particular, the brain showed higher tissue-specificity of ion channel genes, including Gabrd, Gabra6, Gabrg2, Grin2a, and Grin2b. Notably, age-dependent changes in ion channel gene expression were prominently observed in the thymus, including in Aqp1, Clcn4, Hvcn1, Itpr1, Kcng2, Kcnj11, Kcnn3, and Trpm2. …”
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1830“…Notably, we concluded that ALDH5A1 and GABRA3 were disordered by m-miR-184, which might lead to ocular disease. …”
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1831“…Access to this information allows for the improvement of refractive results. We derive the Sayegh-Gabra formula, which uses input and output parameters in a toric calculator to extract toricity ratios that are typically not disclosed. …”
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1832por Wei, Qingtao, Ye, Yi, Chen, Fan, Li, Jienan, Wu, Hao, Fu, Yingqiang, Yan, Youyi, Liao, Linchuan“…The nine SNPs included four SNPs in alcohol-metabolizing genes (ADH1B, ADH1C, ALDH2 and CYP2E1*5B) and five SNPs in genes of neurobiological pathways (GABRA2, OPRM1, CHRNA3, HYKK and SLC6A4). A SNaPshot analysis method was developed to type these SNPs simultaneously, and all samples were typed successfully. …”
Publicado 2018
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1833“…It is mainly caused by mutations in SCN1A gene, encoding type 1 voltage-gated sodium channel α-subunit (NaV1.1), and GABRA1 gene, encoding the α1 subunit of the γ-aminobutyric acid type A (GABA(A)) receptor, while seldom related with SCN9A gene, encoding the voltage-gated sodium channel NaV1.7. …”
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1834por Rajgor, Dipen, Purkey, Alicia M., Sanderson, Jennifer L., Welle, Theresa M., Garcia, Joshua D., Dell’Acqua, Mark L., Smith, Katharine R.“…Here, we identify a role for miR376c in regulating the translation of mRNAs encoding the synaptic α1 and γ2 GABA(A)R subunits, GABRA1 and GABRG2, respectively. Following iLTP induction, transcriptional repression of miR376c is induced through a calcineurin-NFAT-HDAC signaling pathway and promotes increased translation and clustering of synaptic GABA(A)Rs. …”
Publicado 2020
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1835por Horie, Takahiro, Nakao, Tetsushi, Miyasaka, Yui, Nishino, Tomohiro, Matsumura, Shigenobu, Nakazeki, Fumiko, Ide, Yuya, Kimura, Masahiro, Tsuji, Shuhei, Rodriguez, Randolph Ruiz, Watanabe, Toshimitsu, Yamasaki, Tomohiro, Xu, Sijia, Otani, Chiharu, Miyagawa, Sawa, Matsushita, Kazuki, Sowa, Naoya, Omori, Aoi, Tanaka, Jin, Nishimura, Chika, Nishiga, Masataka, Kuwabara, Yasuhide, Baba, Osamu, Watanabe, Shin, Nishi, Hitoo, Nakashima, Yasuhiro, Picciotto, Marina R., Inoue, Haruhisa, Watanabe, Dai, Nakamura, Kazuhiro, Sasaki, Tsutomu, Kimura, Takeshi, Ono, Koh“…Mechanistically, miR-33 deficiency upregulates gamma-aminobutyric acid (GABA)(A) receptor subunit genes such as Gabrb2 and Gabra4. Knock-down of these genes in Dbh-positive neurons rescues the impaired cold-induced thermogenesis in miR-33(f/f) DBH-Cre mice. …”
Publicado 2021
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1836por Pradas, Francisco, Falcón, David, Peñarrubia-Lozano, Carlos, Toro-Román, Víctor, Carrasco, Luis, Castellar, Carlos“…Neuromuscular response (squat jump, countermovement jump and Abalakov jump), muscle damage (alanine aminotransferase, bilirubin, creatine kinase and leukocytes) and hydration status (sodium and creatinine) were evaluated before and after the Guara Somontano Ultratrail Race (108 km distance, with an accumulated slope of 5800 m). …”
Publicado 2021
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1837por Neklyudova, Anastasia, Smirnov, Kirill, Rebreikina, Anna, Martynova, Olga, Sysoeva, Olga“…This segmentation links abnormalities in different genes, such as FMR1, UBE3A, GABRB3, GABRA5, GABRG3, SHANK3, MECP2, TSC1, TSC2, and NF1, that are causative to the above-mentioned syndromes and associated with synaptic transmission and cell growth, as well as with translational and transcriptional regulation and with sensory sensitivity. …”
Publicado 2022
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1838por Estrada-Gómez, Sebastián, Vargas-Muñoz, Leidy Johana, Higuita-Gutiérrez, Luis Felipe“…The population incidence per 100,000 inhabitants was 9.5; the highest rates were found in Vaupés at 116.1 and Guaviare at 79.24. During the last seven years (2014–2020) Colombia produced an average of 21,104 antivenom vials per year, while the annual demand for antivenom is estimated at 54,440 units needed to guarantee access. …”
Publicado 2022
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1839“…(basionym: P. andina subsp. purpurea). A new species (P. glabra sp. nov.) is proposed based on our examination of live plants and herbarium specimens. …”
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1840por Lu, Qirong, Han, Wantong, Wen, Defeng, Guo, Pu, Liu, Yu, Wu, Zhongyuan, Fu, Shulin, Ye, Chun, Wang, Xu, Qiu, Yinsheng“…The compound 18β-glycyrrhetinic acid (GA), a pentacyclic triterpenoid extracted from Glycyrrhiza glabra L. root (liquorice) and with a chemical structure similar to that of steroidal hormones, has become a research focus because of its anti-inflammatory, antiulcer, antimicrobial, antioxidant, immunomodulatory, hepatoprotective and neuroprotective effects, but its potential for the treatment of vascular endothelial inflammatory injury by P. multocida infections has not been evaluated. …”
Publicado 2023
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