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84901por Fonseca, Braúlio, Coelho, Marcelo Santos, Bueno, Carlos Eduardo da Silveira, Fontana, Carlos Eduardo, Martin, Alexandre Sigrist De, Rocha, Daniel Guimarães Pedro“…Materials and Methods Sixty-four patients requiring endodontic treatment of single-rooted maxillary teeth with necrotic pulps were included in this study. The root canal treatments were performed in a single visit using a size 40.06 single-file reciprocating system under 2.5% NaOCl irrigation. …”
Publicado 2019
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84902por Li, Yue, Zhao, Weimin, Wang, Li, Chen, Yueping, Zhang, Hao, Wang, Tian, Yang, Xiaoyang, Xing, Fei, Yan, Junshu, Fang, Xiaomin“…Hydrogen peroxide increased the apoptotic and necrotic rate, boosted reactive oxygen species (ROS) generation, and disturbed the transcriptional expression of genes associated with antioxidant defense and apoptosis in IPEC-1 cells. …”
Publicado 2019
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84903por Asztalos, Elizabeth V., Barrington, Keith, Lodha, Abhay, Tarnow-Mordi, William, Martin, Andrew“…BACKGROUND: In Canada alone, almost 3000 VLBW infants are born and treated annually with almost 1200 going onto death or survival with severe brain injury, chronic lung disorders, aggressive retinopathy of prematurity, late-onset sepsis, or significant necrotizing enterocolitis. Lactoferrin is an antimicrobial, antioxidant, anti-inflammatory iron-carrying, bifidogenic glycoprotein found in all vertebrates and in mammalian milk, leukocytes and exocrine secretions. …”
Publicado 2020
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84904por Twittenhoff, Christian, Heroven, Ann Kathrin, Mühlen, Sabrina, Dersch, Petra, Narberhaus, Franz“…Among the temperature-regulated virulence genes of Yersinia pseudotuberculosis is cnfY coding for the cytotoxic necrotizing factor (CNF(Y)), a multifunctional secreted toxin that modulates the host’s innate immune system and contributes to the decision between acute infection and persistence. …”
Publicado 2020
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84905por Bele, D., Kojc, N., Perše, M., Černe Čerček, A., Lindič, J., Aleš Rigler, A., Večerić-Haler, Ž.“…Kidney biopsy revealed proliferative, necrotizing immunocomplex glomerulonephritis. Half a year later, following intravenous immunoglobulins, glucocorticoids, antibiotic therapy and surgical valve repair, the creatinine level decreased and c-ANCA and cryoglobulins disappeared. …”
Publicado 2020
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84906“…Very rarely, statins induce an anti-HMGCR positive immune-mediated necrotizing myopathy. Diagnosing SRM in clinical practice can be challenging, particularly for mild SRM that is frequently due to alternative aetiologies and the nocebo effect. …”
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84907por Imran, Muhammad, Al Kury, Lina Tariq, Nadeem, Humaira, Shah, Fawad Ali, Abbas, Muzaffar, Naz, Shagufta, Khan, Arif-ullah, Li, Shupeng“…Furthermore, ethanol administration induced neuroinflammation, as demonstrated by elevated expression of tumor necrotic factor (TNF-α), nuclear factor κB (NF-κB), cyclooxygenase-2 (COX2), and ionized calcium-binding adapter molecule-1 (Iba-1), which was further validated by enzyme-linked immunosorbent assay (ELISA). …”
Publicado 2020
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84908por Komaki, Hirofumi, Maegaki, Yoshihiro, Matsumura, Tsuyoshi, Shiraishi, Kazuhiro, Awano, Hiroyuki, Nakamura, Akinori, Kinoshita, Satoru, Ogata, Katsuhisa, Ishigaki, Keiko, Saitoh, Shinji, Funato, Michinori, Kuru, Satoshi, Nakayama, Takahiro, Iwata, Yasuyuki, Yajima, Hiroyuki, Takeda, Shin’ichi“…OBJECTIVE: Duchenne muscular dystrophy (DMD) is a progressive muscular disease characterized by chronic cycles of inflammatory and necrotic processes. Prostaglandin D(2) (PGD(2)) is produced by hematopoietic PGD synthase (HPGDS), which is pathologically implicated in muscle necrosis. …”
Publicado 2020
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84909por Li, Xinzhong, Guo, Shengcun, Xu, Tong, He, Xiang, Sun, Yili, Chen, Xiaoqiang, Cao, Shiping, Si, Xiaoyun, Liao, Wangjun, Liao, Yulin, Han, Yuan, Bin, Jianping“…Microvessel density (MVD) was assessed by immunofluorescence and immunohistochemical methods. The plaque necrotic center/fiber cap (NC/FC) ratio and vulnerability index were calculated to evaluate plaque vulnerability. …”
Publicado 2020
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84910por Fazilat-Panah, Danial, Vakili Ahrari Roudi, Somaye, Keramati, Alireza, Fanipakdel, Azar, Sadeghian, Mohammad Hadi, Homaei Shandiz, Fatemeh, Shahidsales, Soodabeh, Javadinia, Seyed Alireza“…CONCLUSION: Our findings showed statistically insignificant changes in the level of Caspase-cleaved- (M30) and uncleaved- (M65) cytokeratin 18 fragments (apoptotic and necrotic indicators, respectively) during neoadjuvant chemotherapy in patients with breast cancer. …”
Publicado 2020
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84911por Vujić, Nemanja, Korbelius, Melanie, Sachdev, Vinay, Rainer, Silvia, Zimmer, Andreas, Huber, Anton, Radović, Branislav, Kratky, Dagmar“…Atherosclerotic lesions were markedly smaller with beneficial alterations in plaque composition as evidenced by reduced macrophage infiltration and necrotic core size despite unaltered collagen content, indicating improved plaque stability. …”
Publicado 2020
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84912por Yan, Huzheng, Luo, Ma, Wang, Lifei, Qiu, Zhenkang, Mo, Zhiqiang, Xiang, Zhanwang, Zhang, Yanling, Chen, Guanyu, Zhong, Zhihui, Wang, Xiuchen, Gao, Fei, Zhang, Fujun“…Metastatic lymph node with uniform density (p-0.009), clear boundaries (p-0.011), regular morphology (P < 0.001), and < 3 organs at risk of metastasis (p-0.020) were associated with better LTPFS. Necrotic lymph nodes (p < 0.001), fusion (p-0.003), and invasion of vessels visible on images (p < 0.001) were associated with poor LTPFS. …”
Publicado 2020
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84913por Sehl, Julia, Hölper, Julia E., Klupp, Barbara G., Baumbach, Christina, Teifke, Jens P., Mettenleiter, Thomas C.“…Herpes Simplex Encephalitis (HSE) is characterized by mainly unilateral necrotizing inflammation effacing the frontal and mesiotemporal lobes with rare involvement of the brainstem. …”
Publicado 2020
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84914por Avumegah, Michael S., Waidyatillake, Nilakshi T., Michalski, Wojtek P., O’Brien, Daniel P., Nelson, Tiffanie M., Athan, Eugene“…Buruli ulcer (BU) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans. …”
Publicado 2020
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84915por Gonda, Masanori, Osuga, Tatsuya, Ikura, Yoshihiro, Hasegawa, Kazunori, Kawasaki, Kentaro, Nakashima, Takatoshi“…In each case, severe intestinal damage was confirmed during surgery, and the necrotic portion, if present, was removed. Non-occlusive mesenteric ischemia was the most common cause (n = 4). …”
Publicado 2020
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84916por Fevereiro, João, Sajjadi, Nikta, Fraga, Alexandra G., Teixeira, Pedro M., Pedrosa, Jorge“…BACKGROUND: Buruli ulcer (BU) is a necrotizing skin disease, caused by Mycobacterium ulcerans, with poorly understood acquisition risk factors. …”
Publicado 2020
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84917por Gu, Fei-fei, Wu, Jing-jing, Liu, Yang-yang, Hu, Yue, Liang, Jin-yan, Zhang, Kai, Li, Ming, Wang, Yan, Zhang, Yong-an, Liu, Li“…Compared with macrophages, infDCs had a weaker capacity to phagocytose necrotic tumor cell lysates. However, only infDCs induced autologous memory CD4(+) T-cell differentiation into Th1 cells. …”
Publicado 2020
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84918por Zhu, Weiwen, Guo, MinKang, Yang, Wu, Tang, Min, Chen, Tingmei, Gan, Delu, Zhang, Dian, Ding, Xiaojuan, Zhao, Anping, Zhao, Pei, Yan, Wenlong, Zhang, Jian“…Taken together, our study results revealed that in the progress of ONFH, exosomes from the pathological bone brought about the failure of MSCs repairing the necrotic bone for lack of some critical proteins, like integrin CD41, and prompted the progression of experimentally induced ONFH-like status in the rat. …”
Publicado 2020
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84919“…All patients underwent contouring of GD-enhancing tumor (C+), peritumoral T2 (pT2), necrotic and non-enhancing tumor core (NCR/NET). Images are co-registered to the anatomical template and skull-stripped. …”
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84920por Aguiar, Talita Ferreira Marques, Rivas, Maria Prates, Costa, Silvia, Maschietto, Mariana, Rodrigues, Tatiane, Sobral de Barros, Juliana, Barbosa, Anne Caroline, Valieris, Renan, Fernandes, Gustavo R., Bertola, Debora R., Cypriano, Monica, Caminada de Toledo, Silvia Regina, Major, Angela, Tojal, Israel, Apezzato, Maria Lúcia de Pinho, Carraro, Dirce Maria, Rosenberg, Carla, Lima da Costa, Cecilia Maria, Cunha, Isabela W., Sarabia, Stephen Frederick, Terrada, Dolores-López, Krepischi, Ana Cristina Victorino“…In inflammatory regions of hepatoblastomas, CX3CL1/CX3CR1 were not detected in the infiltrated lymphocytes, in which they should be expressed in normal conditions, whereas necrotic regions exhibited negative labeling in tumor cells, but strongly positive infiltrated lymphocytes. …”
Publicado 2020
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