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  1. 85041
    “…The decrease in the number of glioma cells after silencing of the TAC1R siRNA gene was due to apoptotic and necrotic mechanisms. In human primary fibroblast cultured cells, TAC1R silencing by siRNA did not produce any change in cell viability. …”
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    The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
  2. 85042
    “…The most common complication was necrotizing fasciitis and death followed by septicemia. …”
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    Management of Ludwig's Angina at a Tertiary Care Hospital in Western Region of India
  3. 85043
    “…Background: Combination therapy with the administration of GW5074 and sorafenib significantly induced necrotic death in various cancer cells in vivo, as well as prolonging the survival of an animal disease model due to significant suppression of the primary and metastatic lesions. …”
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    Phase I Targeted Combination Trial of Sorafenib and GW5074 in Patients with Advanced Refractory Solid Tumors
  4. 85044
    “…Clostridium perfringens is an important pathogen for both humans and animals, causing human foodborne disease and necrotic enteritis in poultry. In the present study, a C. perfringens-specific phage, vB_CpeS_BG3P (designated as BG3P hereafter), was isolated from chicken farm sewage. …”
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    The Broad Host Range Phage vB_CpeS_BG3P Is Able to Inhibit Clostridium perfringens Growth
  5. 85045
    “…However, it is able to cope with long-term salt stress without any signs of damage, such as chlorophyll depletion, leaf browning or necrotic spots probably due to maintenance of K homeostasis and proline accumulation, which alleviate the toxic effect of chloride.…”
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    How chrysanthemum (Chrysanthemum × grandiflorum) ‘Palisade White’ deals with long-term salt stress
  6. 85046
    “…Some dogs were subjected to surgical excision of necrotized tissue including limb amputation. We observed the following systemic clinical effects in envenomed dogs: neurotoxicity (13%), acute kidney injury (AKI) (14%) and coagulopathy (16%). …”
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    Clinico-epidemiology and management of hump-nosed pit viper (Hypnale spp.) bites in dogs
  7. 85047
    “…Muscle biopsies of patients with HMGCR autoantibodies showed findings consistent with immune-mediated necrotizing myopathy in all cases except for one. Five (38%) patients required treatment with intravenous immunoglobulin compared to seven (2.3%) without this antibody. …”
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    Screening for Anti-HMGCR Antibodies in a Large Single Myositis Center Reveals Infrequent Exposure to Statins and Diversiform Presentation of the Disease
  8. 85048
    “…Therefore, we re-examined GPR56 expression in public domain spatial gene expression data and single-cell expression data for GBM, which revealed that GPR56 expression was high in cellular tumors, infiltrating tumor cells, and proliferating cells, low in microvascular proliferation and peri-necrotic areas of the tumor, especially in hypoxic mesenchymal-like cells. …”
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    Multi-Omics Analysis of Glioblastoma and Glioblastoma Cell Line: Molecular Insights Into the Functional Role of GPR56 and TG2 in Mesenchymal Transition
  9. 85049
    “…In patients with enlarged or necrotic lymph nodes, the location, size and pattern of infiltration of adjacent organs were recorded. …”
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    Radiological evaluation of metastatic lymph nodes in carcinoma cervix with emphasis on their infiltrative pattern
  10. 85050
    “…Because necroptosis is involved in necrotic core development in atherosclerotic plaques, we investigated the effects of a RIPK1(S25D/S25D) mutation, which prevents activation of RIPK1 kinase, on atherogenesis in ApoE(−/−) mice. …”
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    The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach
  11. 85051
    “…Systolic blood pressure (SBP) and heart rate were monitored. Serum levels of nitric oxide (NO), interleukin (IL)-1β, IL-2, and tumor necrotic factor (TNF)-α were measured. …”
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    Gao-Zi-Yao improves learning and memory function in old spontaneous hypertensive rats
  12. 85052
    “…An EGD repeated 14 days after discharge showed complete healing of the necrotic-like mucosal change without stricture formation of the esophagus. …”
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    Gurvits syndrome: a case of acute esophageal necrosis associated with diabetic ketoacidosis
  13. 85053
    “…Resection of residual tumour showed necrotic tissue only. There continues to be a sustained response to Everolimus for over 12 months. …”
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    HGG-32. Durable response to mTOR inhibitor after failing Checkpoint inhibitors in Ultra-Hypermutated High grade glioma in context of CMMRD
  14. 85054
    “…Caries lesions during cement repairs are a severe issue, and developing a unique antimicrobial restorative biomaterial can help to reduce necrotic lesion recurrence. As a result, Thymus vulgaris extract was used to biosynthesize copper nanoparticles (TVE-CuNPs) exhibiting different characteristics (TVE). …”
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    Comparison and Advanced Antimicrobial Strategies of Silver and Copper Nanodrug-Loaded Glass Ionomer Cement against Dental Caries Microbes
  15. 85055
    “…The patients were classified to be at high risk because of cardiogenic shock, associated complex cardiac malformations, neonatal infection, necrotizing enterocolitis, and extracardiac conditions, respectively. …”
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    Surgical Treatment Following Stent Angioplasty for High-Risk Neonates With Critical Coarctation of the Aorta
  16. 85056
    “…Studies are now focused on understanding molecular mechanisms of chemoresistance, the tumor microenvironment, due to hypoxic and necrotic areas, cytoskeleton and extracellular matrix remodeling, and in controlling blood brain barrier permeabilization to improve drug delivery. …”
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    Obstacles to Glioblastoma Treatment Two Decades after Temozolomide
  17. 85057
    por Silva, Diogo J., Mesquita, Alexandra
    Publicado 2022
    “…DIAGNOSIS: Cervicothoracoabdominal computed tomography confirmed the presence of two large necrotic lymphadenopathies in the cervical and axillary lymphatic chains, and bone scintigraphy revealed dorsal (D11) and lumbar (L5) metastatic lesions. …”
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    Complete and long-lasting response to immunotherapy: A case report of urothelial cancer
  18. 85058
    “…BACKGROUND: Sarcoidosis features non-necrotizing granulomas consisting mainly of activated CD4-lymphocytes. …”
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    Immune-Checkpoint Expression on CD4, CD8 and NK Cells in Blood, Bronchoalveolar Lavage and Lymph Nodes of Sarcoidosis
  19. 85059
    “…The histopathological findings showed that primary tumor and PVTT were mostly necrotic with residues of viable tumor cells observed in some areas. …”
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    Conversion surgery for hepatocellular carcinoma with portal vein tumor thrombus after successful atezolizumab plus bevacizumab therapy: a case report
  20. 85060
    “…In vivo experiments revealed that the extract reduced tumor volume, inhibited the proliferation of HCC cells, and expanded the necrotic area of the tumor. Immunohistochemical results showed that the expression levels of CD31, PDGFB, VEGF, VWF, and PDGFRB in the HCC-PDX tumor tissues were all downregulated by MTE in a dose-dependent manner. …”
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    Extract of Marsdenia tenacissima (Roxb.) Moon [Apocynaceae] Suppresses Hepatocellular Carcinoma by Inhibiting Angiogenesis
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