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86021“…Enhanced scans showed mild or moderate enhancement, with large-diameter lesions unable to enhance central, low-density, necrotic areas. The ROC curve showed that the area under the curve (AUC) and the sensitivity and specificity of MSCT combined with CA19-9, Bcl-2, and CYFRA21-1 detection were all higher than for esophageal lesions detected by individual indicators. …”
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86022“…Primary outcome was a composite of adverse neonatal outcomes such as death, sepsis, necrotizing enterocolitis, grade-3 or -4 intraventricular hemorrhage, seizure within 24 hours of delivery, intubation within 24 hours of delivery, and requiring cardiopulmonary resuscitation. …”
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86023por Duan, Lufen, Zhou, Qin, Feng, Zongtai, Zhu, Chenqi, Cai, Yan, Wang, Sannan, Zhu, Meiying, Li, Jingjing, Yuan, Yunlong, Liu, Xin, Sun, Jiantong, Yang, Zuming, Tang, Lian“…Multiple logistic regression analysis indicated that the independent risk factors of LIT were lower weight at medication, younger gestational ages, late-onset sepsis, necrotizing enterocolitis, mechanical ventilation, longer durations of LZD treatment, and lower baseline of platelet level. …”
Publicado 2022
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86024por Kumar, S. P. Jeevan, Susmita, C., Sripathy, K. V., Agarwal, Dinesh K., Pal, Govind, Singh, Arvind Nath, Kumar, Sanjay, Rai, Abhishek Kumar, Simal-Gandara, Jesus“…Thus, hybridization among diverse gene pool could result in more heterotic combinations ultimately enhancing genetic gain, crop yield and resistance to various stress factors. …”
Publicado 2021
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86025por Tanaka, Chiharu, Furihata, Kaoru, Naganuma, Seiji, Ogasawara, Mitsunari, Yoshioka, Reiko, Taniguchi, Hideki, Furihata, Mutsuo, Taniuchi, Keisuke“…In subcutaneous xenografts of S2-013-conventional mice, no blood vessel density or widely expanding areas of necrotic regions were present. Consequently, serum levels of CA19-9 in the S2-013-organoid model correlated with tumor volumes. …”
Publicado 2022
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86026por Li, Liang, Meng, Xingchen, Liu, Liyuan, Xiang, Yujuan, Wang, Fei, Yu, Lixiang, Zhou, Fei, Zheng, Chao, Zhou, Wenzhong, Cui, Shude, Tian, Fuguo, Fan, Zhimin, Geng, Cuizhi, Cao, Xuchen, Yang, Zhenlin, Wang, Xiang, Liang, Hong, Wang, Shu, Jiang, Hongchuan, Duan, Xuening, Wang, Haibo, Li, Guolou, Wang, Qitang, Zhang, Jianguo, Jin, Feng, Tang, Jinhai, Li, Liang, Zhu, Shiguang, Zuo, Wenshu, Ye, Chunmiao, Yin, Gengshen, Ma, Zhongbing, Huang, Shuya, Yu, Zhigang“…Furthermore, we found that the expressions of rs4655555-associated gene LEPR and leptin receptor overlapping transcript (LEPROT) were upregulated in breast cancer tumor tissues compared with adjacent normal tissues, and a higher expression of LEPR in tumor tissues was correlated with poor prognosis of breast cancer patients using The Cancer Genome Atlas Breast Invasive Carcinoma (TCGA-BRCA) data. …”
Publicado 2022
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86027por Hashemkhani, Mahshid, Loizidou, Marilena, MacRobert, Alexander J., Yagci Acar, Havva“…The incorporation of ALA delivery by the AIS QDs, which on their own do not cause phototoxicity, elicited significant cell death due to enhanced light-induced ROS generation and apoptotic/necrotic cell death, reducing the IC50 for ALA dramatically to about 0.1 and 0.01 mM in anionic and cationic AIS QDs, respectively. …”
Publicado 2022
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86028“…This review discusses critical molecular mechanisms by which exogenous particles (i.e., silica, asbestos, carbon nanotubes, titanium dioxide, aluminum-containing salts) and endogenous particles (i.e., monosodium urate, cholesterol crystals, calcium-containing salts) may promote unresolved inflammation and autoimmunity by inducing toxic responses in myeloid-lineage phagocytes with emphases on inflammasome activation and necrotic and programmed cell death pathways. A prototypical example is occupational exposure to respirable crystalline silica, which is etiologically linked to systemic lupus erythematosus (SLE) and other human autoimmune diseases. …”
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86029“…METHODS: From March 2012 to January 2016, 12 patients with aseptic necrosis of lunate bone underwent necrotic lunate bone extirpation assisted by wrist arthroscopy, and the scaphocapitate joint treated with fusion‐stabilization were selected. …”
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86030“…The objective of this study is to examine ICGA and SWIG fluorescence in burns requiring excision and grafting, and to correlate SWIG fluorescence to microscopic localization of inflamed and necrotic tissue. METHODS: Deep partial thickness, indeterminate depth or full thickness burns were identified in adult patients scheduled for excision and grafting. 24 hours prior to surgery, baseline bright light and fluorescence images were obtained before the administration of up to 5 mg/kg ICG intravenously. …”
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86031por van Kuijk, Kim, Demandt, Jasper A F, Perales-Patón, Javier, Theelen, Thomas L, Kuppe, Christoph, Marsch, Elke, de Bruijn, Jenny, Jin, Han, Gijbels, Marion J, Matic, Ljubica, Mees, Barend M E, Reutelingsperger, Chris P M, Hedin, Ulf, Biessen, Erik A L, Carmeliet, Peter, Baker, Andrew H, Kramann, Rafael K, Schurgers, Leon J, Saez-Rodriguez, Julio, Sluimer, Judith C“…Human plaque BNIP3 mRNA was positively associated with plaque necrotic core size, suggesting similar pro-apoptotic effects in human. …”
Publicado 2021
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86032por Fenoglio, Roberta, Sciascia, Savino, Rossi, Daniela, Naretto, Carla, Alpa, Mirella, Roccatello, Dario“…After 6 months we observed a remarkable improvement in the necrotizing skin ulcers and a substantial amelioration of the electrophysiological parameters of motor and sensory peripheral neuropathy. …”
Publicado 2022
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86033por Kamphof, Hester D., Gordijn, Sanne J., Ganzevoort, Wessel, Verfaille, Viki, Offerhaus, Pien M., Franx, Arie, Pajkrt, Eva, de Jonge, Ank, Henrichs, Jens“…Severe adverse perinatal outcomes were defined as a composite of one or more of the following: perinatal death, Apgar score < 4 at 5 min, impaired consciousness, asphyxia, seizures, assisted ventilation, septicemia, meningitis, bronchopulmonary dysplasia, intraventricular hemorrhage, periventricular leukomalacia, or necrotizing enterocolitis. RESULTS: We found the highest rates of severe adverse perinatal outcomes among the smallest newborns (< 3(rd) percentile) (6.2% for the Visser reference curve, 8.6% for the Hoftiezer chart and 12.0% for the INTERGROWTH chart). …”
Publicado 2022
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86034por Lin, Ching-Kai, Fan, Hung-Jen, Yu, Kai-Lun, Chang, Lih-Yu, Wen, Yueh-Feng, Keng, Li-Ta, Ho, Chao-Chi“…Univariate analysis revealed that TB microorganisms would be more easily cultivated when lesions had an abscess or cavity on the computed tomography (CT) image (presence vs. absence; 62.5 vs. 26.3%, p = 0.022), heterogeneous echogenicity on the EBUS finding (heterogeneous vs. homogeneous; 93.3 vs. 21.4%, p = 0.001), or a necrotic pattern via histologic study (presence vs. absence; 70.6 vs. 30.8%, p = 0.013). …”
Publicado 2022
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86035“…After blue light illumination, RPE cells exhibited necrotic characteristics accompanied by destruction of cell membranes and vacuole formation, but nuclear membranes remained intact. …”
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86036por Najem, Hinda, Ott, Martina, Kassab, Cynthia, Rao, Arvind, Rao, Ganesh, Marisetty, Anantha, Sonabend, Adam M., Horbinski, Craig, Verhaak, Roel, Shankar, Anand, Krishnan, Santhoshi N., Varn, Frederick S., Arrieta, Víctor A., Gupta, Pravesh, Ferguson, Sherise D., Huse, Jason T., Fuller, Gregory N., Long, James P., Winkowski, Daniel E., Freiberg, Ben A., James, Charles David, Platanias, Leonidas C., Lesniak, Maciej S., Burks, Jared K., Heimberger, Amy B.“…In lung metastases, T cells interacted with CD163(+) macrophages as dyads and clusters at the brain-tumor interface and within the tumor itself and as clusters within the necrotic core. In contrast, gliomas typically lacked dyad and cluster interactions, except for T cell CD68(+) cell dyads within the tumor. …”
Publicado 2022
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86037por Oreska, Sabina, Storkanova, Hana, Kudlicka, Jaroslav, Tuka, Vladimir, Mikes, Ondrej, Krupickova, Zdislava, Satny, Martin, Chytilova, Eva, Kvasnicka, Jan, Spiritovic, Maja, Hermankova, Barbora, Cesak, Petr, Rybar, Marian, Pavelka, Karel, Senolt, Ladislav, Mann, Herman, Vencovsky, Jiri, Vrablik, Michal, Tomcik, Michal“…METHODS: Thirty nine patients with IIM (32 females; mean age 56; mean disease duration 4.8 years; dermatomyositis: n = 16, polymyositis: n = 7, immune-mediated necrotizing myopathy: n = 8, anti-synthetase syndrome: n = 8) and 39 age-/sex-matched HC (32 females, mean age 56) without rheumatic diseases were included. …”
Publicado 2022
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86038por Zhao, Bing, Dai, Tingjun, Zhao, Dandan, Ma, Xiaotian, Zhao, Cuiping, Li, Ling, Sun, Yuan, Zhang, Yongqing, Yan, Yaping, Lu, Jian-Qiang, Liu, Fuchen, Yan, Chuanzhu“…In comparison, we also performed muscle IHC in patients with selective type II fiber atrophy (n = 22), neurogenic atrophy (n = 22), mitochondrial myopathy (n = 5), immune-mediated necrotizing myopathy (n = 5), and normal controls (n = 5). …”
Publicado 2022
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86039por Chen, Wenhuan, Li, Jianxiong, Guo, Wenxuan, Gao, Shihua, Wei, Qiushi, Li, Ziqi, He, Wei“…There were no significant differences in the final clinical score and arthritic changes among different Japanese Investigation Committee (JIC) classification, the degree of collapse and the size of the necrotic (P > 0.05). CONCLUSIONS: In AYA patients, SHD combined with bone grafting is a potentially good option for hip preservation in ONFH. …”
Publicado 2022
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86040por Tomkowiak, Agnieszka, Nowak, Bartosz, Sobiech, Aleksandra, Bocianowski, Jan, Wolko, Łukasz, Spychała, Julia“…DNA analysis in the selection of parental components for heterotic crosses is a very important tool for breeders. …”
Publicado 2022
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