“…RESULTS: Macroscopically, the resistant response of accession SA27063 was characterised by small, hypersensitive-like spots following inoculation while the susceptible interaction with accessions A17 and SA3054 showed necrotic lesions and spreading chlorosis. No unique cytological differences were observed during early infection (<48 h) between the resistant and susceptible genotypes, except pathogen growth was restricted to one or a few host cells in SA27063. …”
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“…This composite endpoint of re-operation includes a narrow spectrum of patient-important procedures: irrigation and debridement for infected wound, revision and closure for wound dehiscence, wound coverage procedures for infected or necrotic wound, bone grafts or implant exchange procedures for established nonunion in patients with postoperative fracture gaps less than 1 cm, intramedullary nail dynamizations in the operating room, and fasciotomies for compartment syndrome. …”
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“…Histologically, these tumors are characterized by pleomorphic and polygonal cell population together with mitotic figures, necrotic foci and various numbers inflammatory foci. …”
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“…Vaccinated IL15KO/NeuT mice showed less necrotic tumors with fewer CD3+ lymphocyes and lacked perforin-positive infiltrating cells compared to NeuT mice. …”
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“…RESULTS: 3-BrPA could activate dose-dependent apoptosis (type 1 PCD) and regulated necrosis (type 3 PCD) of T24 (grade III; H-Ras(G12V); p53(ΔY126)), but not RT4 (grade I), cells, with PARP, MLKL, Drp1 and Nec-7-targeted components critically orchestrating necrotic death. However, similarly to RIPK1 and CypD, p53 presented with non-essential contribution to 3-BrPA-induced cellular collapse, while reactivation of mutant p53 with PRIMA-1 resulted in strong synergism of the two agents. …”
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“…P.g. was localized to placental tissues by immunohistochemistry and PCR, and defects in placental tissues of P.g. infected mice included premature rupture of membrane, placental detachment, degenerative changes in trophoblasts and endothelial cells, including necrotic areas. P.g. infection caused significantly increased numbers of polymorphonuclear leukocytes (PMNLs) and macrophages in placental tissues, associated with increased local expression of pro-inflammatory mediators including TNF-α and COX-2. …”
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“…ATP can be transported and/or exocytosed from active cancer cells and released from dying cells in the necrotic core of the cancer. We hypothesized that one of the ATP receptors, the P2X7 receptor (P2X7R) could be an important player in PDAC behaviour. …”
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“…Gross lesions were characterized by multifocal to diffuse hemorrhages around proventricular glands, necrotic (diphtheritic) haemorrhagic ulcers throughout the intestine, disseminated multiple foci of necrosis and pin-point hemorrhages in the spleen parenchyma. …”
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“…The nonuniformly perfused tumor is divided into 2 natural components, namely, the necrotic core and tumor periphery. The outer surface of the breast is assumed to be exposed to the environment, and the heat loss takes place by conduction, convection, radiation, and evaporation. …”
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“…Excluding coccidiostats, the top three most frequently used antimicrobial classes were bacitracin (53% of flocks), virginiamycin (25%) and avilamycin (21%), mainly used for the prevention of necrotic enteritis. Depending on the AMU metric utilized, the relative rankings of the top antimicrobials changed; hence the choice of the AMU metric is an important consideration for any AMU reporting. …”
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“…Several times we perform a necrectomy of necrotic tissue but the wound become bigger and the infection have a progressive intention. …”
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“…Morphological findings are linked to Rhizopus infection (Mucormycosis) NECROTIZING MYOCTIC ACUTE OSTEOMYELITIS. Surgical treatment: Radical debridement with removal of surgical material. …”
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“…Tumors that received NIR-PIT showed evidence of necrotic cell death-associated features upon hematoxylin-eosin staining accompanied by a decrease in Ki-67-positive cells (a cell proliferation marker) by IHC examination. …”
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“…When chronic osteomyelitis develops, therapeutic options are limited, as antimicrobial agents cannot penetrate the necrotic bone, and repeated surgical debridement may be needed. …”
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“…However, the large right suprarenal mass was mostly necrotic with a small (68)Ga-DOTATATE-avid focus. During admission, patient had sudden onset of chest pain, diaphoresis, hypotension and desaturation. …”
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“…MRI abdomen confirmed the 9.1x10.8x13.6cm centrally necrotic hypervascular right adrenal soft tissue mass with no adenopathy. …”
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“…Thymic biopsy may be considered only if the size of the mass does not decrease with euthyroid state or patients with concerning radiological features of AMM such as cystic or necrotic changes, invasion to surrounding structure, or calcification. …”
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“…Patient was then taken for open left adrenalectomy Nov 2014 due to significant growth of adenoma. A 7 cm necrotic mass was removed. Pathology report was consistent with a primary adrenocortical carcinoma with lymphovascular invasion and a ki-67 index <10%. …”
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“…There were no enlarged, enhancing, or necrotic cervical lymph nodes. CT thorax/abdomen/pelvis demonstrated bilateral subcm pulmonary nodules, left adrenal nodule and pancreatic head mass. …”
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“…The mitotic figures ranged from 2 to 5 in every 10 high-power fields, and necrotic foci were observed in one case. Immunohistochemically, the tumor cells were positive for AE1/AE3, Cg A, Syn, CD56, P16, CAM5.2, and PGP9.5 and negative for ER, PR, P63, P40, CK7, and CK20. …”
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