“…The development of the fetal heart is exquisitely controlled by a multitude of factors, ranging from humoral to mechanical forces. …”
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“…AIMS: Heart failure hospitalization is a sentinel event associated with increased mortality risk. …”
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“…Emerging technology allows patients to measure and record their heart rate (HR) remotely by photoplethysmography (PPG) using smart devices like smartphones. …”
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“…A heart simulator, UT-Heart, is a finite element model of the human heart that can reproduce all the fundamental activities of the working heart, including propagation of excitation, contraction, and relaxation and generation of blood pressure and blood flow, based on the molecular aspects of the cardiac electrophysiology and excitation-contraction coupling. …”
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Materias: “…Congenital Heart Disease…”
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“…BACKGROUND: There is a complex relationship between heart failure (HF) clinic services and health outcomes. …”
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“…AIM: Heart failure (HF) poses a unique medical burden of high morbidity and mortality. …”
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“…Ischemic heart disease is the leading cause of death worldwide. …”
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“…Heart failure is a complex syndrome responsible for high rates of death and hospitalization. …”
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“…BACKGROUND: The HeartLogic algorithm measures data from multiple implantable cardioverter‐defibrillator‐based sensors and combines them into a single index. …”
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“…AIMS: Heart rate reduction therapy using ivabradine, a selective inhibitor of the funny current of the sinoatrial node, is widely used in the systolic heart failure cohort. …”
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“…The bidirectional link between heart and brain has intrigued scientists for ages, but little is known on the underlying mechanism. …”
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“…Organoid models of early tissue development have been produced for the intestine, brain, kidney and other organs, but similar approaches for the heart have been lacking. Here we generate complex, highly structured, three-dimensional heart-forming organoids (HFOs) by embedding human pluripotent stem cell aggregates in Matrigel followed by directed cardiac differentiation via biphasic WNT pathway modulation with small molecules. …”
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“…Among these four groups, patients with heart rate (HR) ≥ 60 beats/min with no BBs group had the lowest cumulative death-free survival rate. …”
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“…Due to the need for continuous work, the heart uses up to 8% of the total energy expenditure. …”
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“…Any loss or dysregulation of signaling pathways in cardiac NCCs can lead to abnormal cardiovascular development during embryogenesis, resulting in abnormalities categorized as congenital heart defects (CHDs). This review focuses on the contributions of cardiac NCCs to cardiovascular formation, discusses cardiac defects caused by a disruption of various regulatory factors, and summarizes the role of multiple signaling pathways during embryonic development. …”
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“…Moral rule adherence was assessed with self-report measure and integration abilities were assessed with a resting state measure of heart rate variability (HRV), which reflects prefrontal–(para-)limbic engagement during the integration of physical and neural processes. …”
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