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19221por Shepherd, Rebecca F., Kerns, Jemma G., Ranganath, Lakshminarayan R., Gallagher, James A., Taylor, Adam M.“…It is these “rarer forms of disease” that William Harvey referred to that offer novel insights into more common conditions through their more extreme presentations. …”
Publicado 2021
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19222por Karim, Tasneem, Muhit, Mohammad, Jahan, Israt, Galea, Claire, Morgan, Catherine, Smithers-Sheedy, Hayley, Badawi, Nadia, Khandaker, Gulam“…Children registered on the Bangladesh CP Register (BCPR) were recruited in two groups for this study: Group A received a comprehensive six-month long community-based caregiver-led intervention program at the “Shishu Shorgo” (Bengali title, which translates to ‘Children’s Heaven’) Early Intervention and Rehabilitation Centres developed to support participants from the BCPR. …”
Publicado 2021
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19223por Korporaal, Suzanne J. A., van der Sluis, Ronald J., Van Eck, Miranda, Hoekstra, Menno“…We evaluated, in a preclinical setting, the impact of a Down syndrome-like hematological/immune phenotype on atherosclerosis susceptibility. Hereto, hypercholesterolemic low-density lipoprotein receptor knockout mice were transplanted with bone marrow from either a trisomic Ts65Dn mouse or euploid wild-type control and subsequently fed a Western-type diet to induce the development of atherosclerotic lesions. …”
Publicado 2021
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19224por Guimarães Alves, Ana Cecília, Sukow, Natalie Mary, Adelman Cipolla, Gabriel, Mendes, Marla, Leal, Thiago P., Petzl-Erler, Maria Luiza, Lehtonen Rodrigues Souza, Ricardo, Rainha de Souza, Ilíada, Sanchez, Cesar, Santolalla, Meddly, Loesch, Douglas, Dean, Michael, Machado, Moara, Moon, Jee-Young, Kaplan, Robert, North, Kari E., Weiss, Scott, Barreto, Mauricio L., Lima-Costa, M. Fernanda, Guio, Heinner, Cáceres, Omar, Padilla, Carlos, Tarazona-Santos, Eduardo, Mata, Ignacio F., Dieguez, Elena, Raggio, Víctor, Lescano, Andres, Tumas, Vitor, Borges, Vanderci, Ferraz, Henrique B., Rieder, Carlos R., Schumacher-Schuh, Artur, Santos-Lobato, Bruno L., Chana-Cuevas, Pedro, Fernandez, William, Arboleda, Gonzalo, Arboleda, Humberto, Arboleda-Bustos, Carlos E., O’Connor, Timothy D., Beltrame, Marcia Holsbach, Borda, Victor“…In adulthood, the ability to digest lactose, the main sugar present in milk of mammals, is a phenotype (lactase persistence) observed in historically herder populations, mainly Northern Europeans, Eastern Africans, and Middle Eastern nomads. …”
Publicado 2021
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19225“…On the other side, Imagene company has developed a procedure for long-term conservation of biospecimen at room temperature based on the confinement of the samples under an anhydrous and anoxic atmosphere maintained inside hermetic capsules. The procedure has been validated by us and others for purified RNA, and for DNA in buffy coat or white blood cells lysates, but a precise determination of purified DNA stability is still lacking. …”
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19226por Hoffmann, Helene, Baldow, Christoph, Zerjatke, Thomas, Gottschalk, Andrea, Wagner, Sebastian, Karg, Elena, Niehaus, Sebastian, Roeder, Ingo, Glauche, Ingmar, Scherf, Nico“…Technically, we used clinical reference data to first fit a model and then generate de novo model simulations of individual patients’ time courses for which we can systematically tune data quality (i.e. measurement error) and quantity (i.e. number of measurements). Based hereon, we compared the prediction accuracy of three different computational methods, namely mechanistic models, generalized linear models, and deep neural networks that have been fitted to the reference data. …”
Publicado 2021
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19227por Genter, Peter, Høeg, Beverley Lim, Hamre, Camilla Jensen, Andersen, Elisabeth Anne Wreford, Dalton, Susanne Oksbjerg, Ribers, Bjørn, Bidstrup, Pernille Envold“…METHODS AND ANALYSIS: Eighty participants will be invited through the Oncology Department at Herlev Hospital, Denmark and randomised to either the intervention or usual care. …”
Publicado 2021
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19228por Babvey, Pouria, Gongora-Svartzman, Gabriela, Lipizzi, Carlo, Ramirez-Marquez, Jose E.“…In this study, the BERT model is first fine-tuned using historical data and then it is used to classify the tweets associated with hurricanes Dorian and Harvey based on the type of information provided; and alongside, the network between users is constructed based on the retweets and replies on Twitter. …”
Publicado 2021
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19229por Bočkaj, Irena, Martini, Tosca E. I., de Camargo Magalhães, Eduardo S., Bakker, Petra L., Meeuwsen-de Boer, Tiny G. J., Armandari, Inna, Meuleman, Saskia L., Mondria, Marin T., Stok, Colin, Kok, Yannick P., Bakker, Bjorn, Wardenaar, René, Seiler, Jonas, Broekhuis, Mathilde J. C., van den Bos, Hilda, Spierings, Diana C. J., Ringnalda, Femke C. A., Clevers, Hans, Schüller, Ulrich, van Vugt, Marcel A. T. M., Foijer, Floris, Bruggeman, Sophia W. M.“…Since H3.3 mutant gliomas also exhibit high levels of copy number alterations, we set out to address if the H3.3K27M oncohistone leads to destabilization of the genome. Hereto, we established a cell culture model allowing inducible H3.3K27M expression and observed an increase in mitotic abnormalities. …”
Publicado 2021
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19230por Graziano, Francesca, Zorzi, Alessandro, Cipriani, Alberto, De Lazzari, Manuel, Bauce, Barbara, Rigato, Ilaria, Brunetti, Giulia, Pilichou, Kalliopi, Basso, Cristina, Perazzolo Marra, Martina, Corrado, Domenico“…Arrhythmogenic Cardiomyopathy (ACM) is a heredo-familial cardiac disease characterized by fibro-fatty myocardial replacement and increased risk of sudden cardiac death. …”
Publicado 2022
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19231“…This connection breaks down approximately 33 ka, with populations remaining isolated until herders entered southern Africa after 2 ka. The timing of this disconnection broadly corresponds with the southward shift of the Intertropical Convergence Zone, which caused periodic flooding of the Zambezi River catchment (an area that connects eastern and southern Africa). …”
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19232por Zhou, Zepeng, Li, Wenqing, Qian, Jun, Liu, Weihong, Wang, Yiming, Zhang, Xijian, Guo, Qinglei, Yashchyshyn, Yevhen, Wang, Qingpu, Shi, Yanpeng, Zhang, Yifei“…As a promising high-frequency alternative, liquid crystal polymers (LCPs) have been widely investigated for use in circuit devices, chip integration, and module packaging over the last decade due to their low loss tangent up to 1.8 THz and good hermeticity. The previous review articles have summarized the chemical properties of LCP films, flexible LCP antennas, and LCP-based antenna-in-package and system-in-package technologies for 5G applications, although these articles did not discuss synthetic LCP technologies. …”
Publicado 2022
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19233por Saddow, Stephen E.“…Such devices are currently implemented using silicon technology, which either has to be hermetically sealed so it does not directly interact with biological tissue or has a short lifetime due to instabilities in vivo. …”
Publicado 2022
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19234“…This study investigates the nature and factors affecting livestock farmers’ choices of climate-smart livestock practices by using a multivariate probit model and then estimates the average effect of these adopted strategies on per capita daily dietary (calorie, protein, and calcium) intake among livestock herders. For this purpose, data were collected from 196 livestock farmers residing in the Punjab province of Pakistan, selected through multistage purposive and random sampling. …”
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19235por Pulliero, Alessandra, Iodice, Simona, Pesatori, Angela Cecilia, Vigna, Luisella, Khalid, Zumama, Bollati, Valentina, Izzotti, Alberto“…Overall, the findings of the linear univariate and multiple linear regression showed an inverse association between long-term PM(10) exposure and adduct levels; this unexpected result might be since the population consists of subjects with an unhealthy BMI, which might show an atypical reaction to airborne urban pollutants; a hermetic response which happens when small amounts of pollutants are present. …”
Publicado 2022
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19236“…CONCLUSION: In this study, emergency medical employees were always faced with stress and challenges to announce the patient's death to families, including the stress of violence against employees. Hereof, personnel had to take unnecessary care actions such as slow resuscitation to transfer the patient to the hospital. …”
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19237por Vula, Violeta, Stavileci, Miranda, Ajeti, Nexhmije, Vula, Vegim, Kuçi, Astrit, Meqa, Kastriot“…BACKGROUND: A hermetic seal at the apical terminus is required for healthy periradicular tissue. …”
Publicado 2022
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19238por Wójcik, Jacek“…One of these explosions was conducted in the vessel used for the electric ignition of EO and the other in a hermetically locked, small volume container. It was shown that the soot comprises a set of C(2)H(4)O homopolymers and copolymers whose characteristic MS patterns are condition‐dependent. …”
Publicado 2021
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19239“…In the present exploratory study, the microbiomes associated with the surfaces of tropical fruits from Northern Argentina, such as white guava, passion fruit and papaya were investigated using a shotgun metagenomic sequencing approach. Hereto, one sample composed of 14 white guava fruits, two samples of passion fruits with each two to three fruits representing the almost ripe and ripe stage of maturity, four samples of papaya with each two to three fruits representing the unripe, almost ripe, and ripe stage of maturity were processed, as well as a sample of closed and a sample of open Japanese medlar flowers. …”
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19240por Pstrowska, Katarzyna, Gunka, Volodymyr, Prysiazhnyi, Yuriy, Demchuk, Yuriy, Hrynchuk, Yurii, Sidun, Iurii, Kułażyński, Marek, Bratychak, Michael“…The process of chemical modification of tar and oxidized bitumen with formalin (a 37% aqueous solution of formaldehyde) in a hermetic container was investigated and the effectiveness of the proposed process was proven. …”
Publicado 2022
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