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  1. 8441
    “…HDACI valproic acid (VPA) has shown potent anticancer effects in vitro and in vivo. …”
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    In Vitro Effect of the Histone Deacetylase Inhibitor Valproic Acid on Viability and Apoptosis of the PLC/PRF5 Human Hepatocellular Carcinoma Cell Line
  2. 8442
    “…By school, the reinfection rate was highest in the Al Hidaib school, whose prevalence was highest at baseline. …”
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    Transmission Dynamics of Schistosoma haematobium among School-Aged Children: A Cohort Study on Prevalence, Reinfection and Incidence after Mass Drug Administration in the White Nile State of Sudan
  3. 8443
    “…In the TNBC cell lines MDA-MB-436, SUM159 and CAL51, cell killing, viral uptake and replication were increased when treated with sublethal doses of the Class-I-selective HDACis Scriptaid, Romidepsin and MS-275. The pan-HDACi, TSA efficiently improved OAd efficacy, both in vitro and in SUM159 xenograft models in vivo. …”
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    HDAC Inhibitors Enhance Efficacy of the Oncolytic Adenoviruses Ad∆∆ and Ad-3∆-A20T in Pancreatic and Triple-Negative Breast Cancer Models
  4. 8444
    por Brecht, Bertolt, 1898-1956
    Publicado 1964
    Tabla de Contenidos: “…Terror y miserias del tercer Reich ; Los fusiles de la madre Carrar ; Los Horacios y los Curiacios.…”
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    Teatro completo /
  5. 8445
    por Zheng, Hanxi, Liu, Xishi, Guo, Sun‐Wei
    Publicado 2023
    “…This, along with the documented HDAC1 upregulation in endometriosis and the overwhelming evidence for the therapeutic potentials of HDACIs, calls for further and in‐depth investigation of epigenetic aberrations of endometriosis in general and of HDACs in particular.…”
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    Corroborating evidence for aberrant expression of histone deacetylase 8 in endometriosis
  6. 8446
    “…Targeting these mechanisms through the use of HDACis, DNMTis, and combination therapies has the potential to improve the efficacy of cancer immunotherapy. …”
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    Cancer immune escape: the role of antigen presentation machinery
  7. 8447
    “…However, the mechanisms of HDACI-associated anti-tumor activity are not yet clearly defined. …”
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    Trichostatin A Targets the Mitochondrial Respiratory Chain, Increasing Mitochondrial Reactive Oxygen Species Production to Trigger Apoptosis in Human Breast Cancer Cells
  8. 8448
    “…TSA and/or 5-aza-dC derived hepatocytes-like cells failed to improve the therapeutic potential in liver damage. We conclude that HDACis enhance hepatic differentiation in a time-dependent manner, while DNMTis do not induce the hepatic differentiation of rBM-MSCs in vitro. …”
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    Effect of Chromatin-Remodeling Agents in Hepatic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells In Vitro and In Vivo
  9. 8449
    “…BACKGROUND: Histone deacetylase inhibitors (HDACis) like vorinostat are promising radiosensitisers in prostate cancer, but their effect under hypoxia is not known. …”
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    Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
  10. 8450
    “…A screen of the FDA-approved drug library identified the anti-cancer agent vorinostat as the strongest hit, suggesting histone deacetylase inhibitors (HDACis) as potent candidates. Indeed, the HDACi-induced expression of MICA specific to HCC cells enhanced natural killer (NK) cell-mediated cytotoxicity in co-culture, which was further reinforced by treatment with an inhibitor of MICA sheddase. …”
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    Novel chemoimmunotherapeutic strategy for hepatocellular carcinoma based on a genome-wide association study
  11. 8451
    “…Histone deacetylase inhibitors (HDACis) comprise a structurally diverse class of compounds with targeted anti-cancer effects. …”
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    Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma
  12. 8452
    “…Furthermore, we demonstrate that the suppression of ALDH1A1 by WT1 can be markedly attenuated by histone deacetylase inhibitors (HDACis). Taken together, we provide evidence to indicate that WT1 and HDACs are strong regulators of endogenous retinoic acid synthetic enzymes in 293 cells, indicating that they may be involved in the regulation of atRA synthesis.…”
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    Regulation of retinoic acid synthetic enzymes by WT1 and HDAC inhibitors in 293 cells
  13. 8453
    “…We found that fisetin effectively inhibited the cell viability of not only parental cells but also histone deacetylase inhibitors-resistant (HDACis-R) cells and enhanced the chemosensitivity of HCC cells. …”
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    Inhibition of Protein Phosphatase 1 Stimulates Noncanonical ER Stress eIF2α Activation to Enhance Fisetin-induced Chemosensitivity in HDAC Inhibitor-resistant Hepatocellular Carcinoma Cells
  14. 8454
    por Hamam, Hussein J., Palaniyar, Nades
    Publicado 2019
    “…Interestingly, in the presence of NETosis-promoting stimuli, high levels of HDACis limit both NETosis and apoptosis, and promote neutrophil survival. …”
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    Post-Translational Modifications in NETosis and NETs-Mediated Diseases
  15. 8455
    “…We studied the unique inhibitor of the histone deacetylases (HDAC) valproate-valpromide of acyclovir (AN446) that upon metabolic degradation release the HDAC inhibitor (HDACI) valproic acid (VPA). Among the HDAC inhibitors that we have tested, only AN446, and to a lesser extent VPA, synergized with doxorubicin (Dox) anti-cancer activity. …”
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    Valproic Acid Prodrug Affects Selective Markers, Augments Doxorubicin Anticancer Activity and Attenuates Its Toxicity in a Murine Model of Aggressive Breast Cancer
  16. 8456
    “…Rapid development of novel pharmacological agents in clinical testing—HDAC inhibitors (HDACi)—targets these master regulators as common means of therapeutic intervention in cancer and immune diseases. …”
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    Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology
  17. 8457
    “…Here, our study demonstrated that inhibition of histone deacetylase (HDAC) by treatment of HDACis activates mitophagy through mediating Parkin acetylation, leading to inhibition of cervical cancer cell proliferation. …”
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    Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
  18. 8458
    “…In this sense, histone deacetylase inhibitors (HDACIs) are interesting anticancer agents that play an important role in the epigenetic regulation of cancer cells. …”
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    Target Design of Novel Histone Deacetylase 6 Selective Inhibitors with 2-Mercaptoquinazolinone as the Cap Moiety
  19. 8459
    Publicado 2005
    Tabla de Contenidos: “…[v. 1] Tijuana/Baja California, Barrios Amparo Sánchez, Cañón de Saíz y Nido de las Águilas --[v. 2] La Paz/Baja California Sur, Barrios Ampliación Lázaro Cárdenas y Ampliación Agustín Olachea --[v. 3] Nogales/Sonora, Barrios Rosarito I y III y Flores Magón --[v. 4] Ciudad Juárez/Chihuahaua, Barrios 16 de Septiembre, López Mateos y Tierra Nueva --[v. 5] Acuña/Coahuila, Barrios San Antonio, Saracho I y II, Enrique Martínez, Tierra y Esperanza y Ampliación Gámez Sumaran --[v. 6] Ciudad Victoria/Tamaulipas, Barrios San Marcos y La Presita --[v. 7] Durango/Durango, Barrios Zona Sur-Oriente, Zona Norte y Zona Sur --[v. 8] Tepic/Nayarit, Barrios El Punto, Zitacua y Landareñas --[v. 9] Aguascalientes/Aguascalientes, Barrios Las Cumbres y El Calvario --[v. 10] Puerto Vallarta/Jalisco, Barrios Ramblases y San Esteban --[v. 11] León/Guanajuato, Barrios 10 de Mayo, Las Joyas, La Soledad-Camino a San Juan, San Juan Bosco y Piletas IV --[v. 12] Colima/Colima, Barrios Jardines del Sol y Solidaridad --[v. 13] Uruapan/Michoacán, Barrios Zona Poniente y Zona Centro --[v. 14] Pachuca/Hidalgo, Barrios Anáhuac, Guadalupe, La Minerva, San Pedro Nopancalco y el Tezontle --[v. 15] Acapulco/Guerrero, Barrios Barrio Nuevo, Barrio Las Torres y Barrios Históricos --[v. 16] Toluca/Estado de México, Barrios San Salvador, La Trinidad, San Gabriel y La Concepción --[v. 17] Tehuacán/Puebla, Barrios Santa Cecilia y San Diego --[v. 18] Coatzacoalcos/Veracruz, Barrios Santa Rosa, Ampliación Santa Rosa y Popular Morelos --[v. 19] Ciudad del Carmen/Campeche, Barrios Caleta Norte y El Caracol --[v. 20] San Cristobal de las Casas/Chiapas, Barrios 1{esc}p0{esc}s de Enero de 1994 y San Martín --…”
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    Estudios urbanísticos y ambientales en 75 barrios correspondientes a 31 ciudades del sistema urbano nacional (SUN)
  20. 8460
    Publicado 2007
    Tabla de Contenidos: “…La organización comunitaria : actor ausente en la reglamentación del Programa 3x1 para Migrantes en Hidalgo -- Cap. 12. El Programa 3x1 para Migrantes en Oaxaca : migración indígena, prácticas comunitarias y costumbres de participación -- Cap. 13. …”
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    El Programa 3x1 para Migrantes : ¿primera política transnacional en México? /
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