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  1. 9141
    “…In this paper, we show that in a mouse model of laser-induced CNV, systemic administration of Butyroyloxymethyl-diethyl phosphate (AN7), a histone deacetylase inhibitor (HDACi), significantly reduced CNV area and vascular leakage, as measured by choroidal flatmounts and fluorescein angiography. …”
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    The Histone Deacetylase Inhibitor AN7, Attenuates Choroidal Neovascularization in a Mouse Model
  2. 9142
    por Bilotta, Anthony J, Cong, Yingzi
    Publicado 2019
    “…SCFAs engage G-protein coupled receptors (GPRs) and act as histone deacetylase inhibitors (HDACi) to module epithelial and immune cell functions in the intestines, where they generally promote an anti-inflammatory state. …”
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    Gut microbiota metabolite regulation of host defenses at mucosal surfaces: implication in precision medicine
  3. 9143
    “…In this article, we present the concept of intelligent digital assistance for clinical operating rooms (IDACO), providing the surgeon assistance in many different situations before and during an ongoing procedure using natural spoken language. …”
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    The next step: intelligent digital assistance for clinical operating rooms
  4. 9144
    “…Moreover, treatment with SAHA, a histone deacetylase inhibitor (HDACi) also known as Vorinostat, or the specific downregulation of HDAC2 or HDAC7 by siRNA, induces the appearance of senescence biomarkers of dermal fibroblasts. …”
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    HDAC2 and 7 down-regulation induces senescence in dermal fibroblasts
  5. 9145
    Publicado 1994
    Libro
    Reserva ecológica de Macaé de Cima, Nova Friburgo, RJ : aspectos florísticos das espécies vasculares /
  6. 9146
    “…In this report, we found that trichostatin A (TSA), an inhibitor of histone deacetylase (HDACi), could induce early differentiation of embryonic stem cells (ESCs) and promote mesodermal lineage differentiation. …”
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    Histone Deacetylase 1 and 3 Regulate the Mesodermal Lineage Commitment of Mouse Embryonic Stem Cells
  7. 9147
    “…It inhibits class II HDAC Homo sapiens (HDACi). The utilization of SAHA has some side effects, one of which is bone loss. …”
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    Exposing the Molecular Screening Method of Indonesian Natural Products Derivate as Drug Candidates for Cervical Cancer
  8. 9148
    “…Growing evidences have revealed that a histone deacetylase inhibitor (HDACi), suberoylanilide hydroxamic acid (SAHA) has anti-fibrotic effect in different diseases. …”
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    SAHA could inhibit TGF-β1/p38 pathway in MI-induced cardiac fibrosis through DUSP4 overexpression
  9. 9149
    Libro
    Certificación de blasones de armas correspondientes a las casas Atenas, Iverville, Rigaud, Riversan, Espina, Arguelles, Valiente y Benagial.
  10. 9150
    “…Therefore, we examined the relationship between HDAC activity and synaptic defects using an HDAC inhibitor (HDACI), BG45, in the human neuroblastoma SH-SY5Y cell line with stable overexpression of Swedish mutant APP (APPsw) and in APP/PS1 transgenic mice during this study. …”
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    A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway
  11. 9151
    por Hidary, David
    Publicado 2023
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    Focused Forecasts: Attention maps for large-scale model understanding in the AtmoRep project
  12. 9152
    “…Future studies that use epigenetic therapies that combine hypomethylating agents with histone deacetylase inhibitors (HDACi) and head-to-head comparison studies of decitabine and 5-azacitidine will provide valuable pre-clinical and clinical data, enhancing our understanding of these drugs.…”
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    An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes
  13. 9153
    por Karlic, Heidrun, Varga, Franz
    Publicado 2011
    “…It co-operates with other nuclear receptors which are influenced by histone acetyl transferases (HATs) as well as several types of histone deacetylases (HDACs). HDAC inhibitors (HDACi) and/or demethylating drugs may contribute to normalization of VD metabolism. …”
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    Impact of vitamin D metabolism on clinical epigenetics
  14. 9154
    “…Previous studies have highlighted the benefit of epigenetic modification by histone deacetylase inhibitor (HDACi) application to dental pulp cells (DPCs), which induces changes to chromatin architecture, promoting gene expression and cellular-reparative events (Duncan et al., 2013 [3]; Paino et al., 2014 [4]). …”
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    Transcriptional profiling of suberoylanilide hydroxamic acid (SAHA) regulated genes in mineralizing dental pulp cells at early and late time points
  15. 9155
    “…Gene expression analysis of clinical lymphoma samples suggests that peroxisomes are involved in mediating drug resistance to the histone deacetylase inhibitor (HDACi) Vorinostat (Vor), which promotes ROS-mediated apoptosis. …”
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    Peroxisomes protect lymphoma cells from HDAC inhibitor-mediated apoptosis
  16. 9156
    “…We provide evidence that combinatorial HDACi/(+)-JQ1 treatment spurs synergistic Golgi dispersal in several cancer cell lines, pinpointing a possible link between drug-induced toxicity and Golgi morphology alterations.…”
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    Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1
  17. 9157
    “…Histone deacetylase inhibitors (HDACi) can affect many tumors by modulating key biological functions including autophagy. …”
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    Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia
  18. 9158
    “…Thus, we report three patients with CNS-IVL successfully treated with a CNS-centric approach consisting of high-dose methotrexate (HDMTX) and high-dose Ara-C (HiDAC) based CNS-directed chemoimmunotherapy (CIT) alternating with anthracycline-based CIT. …”
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    Intravascular Large B Cell Lymphoma with CNS Involvement Successfully Treated with High-Dose Methotrexate and High-Dose Ara-C Based CNS-Directed Chemoimmunotherapy Alternating with Anthracycline Based Chemoimmunotherapy
  19. 9159
    “…After mutation of the HDAC-binding site of YY1 or HDAC inhibitor (HDACi) treatment, YY1 was separated from HDAC1/3, which resulted in an excessive LLPS state, thereby inhibiting the expression of METTL3 and the proliferation of AML cells. …”
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    HDAC1/3-dependent moderate liquid–liquid phase separation of YY1 promotes METTL3 expression and AML cell proliferation
  20. 9160
    “…We investigated the effect of the histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA, Vorinostat™) on the immunomodulatory effect and cytokine profile of MSC derived from bone marrow and pediatric tumors. …”
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    Epigenetic Modification of Mesenchymal Stromal Cells Derived from Bone Marrow and Embryonal Tumors to Facilitate Immunotherapeutic Approaches in Pediatric Malignancies
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