“…STUDY QUESTION: Does the European Society of Human Reproduction and Embryology–European Society for Gynaecological Endoscopy (ESHRE–ESGE) classification of female genital tract malformations significantly increase the frequency of septate uterus diagnosis relative to the American Society for Reproductive Medicine (ASRM) classification? SUMMARY ANSWER: Use of the ESHRE–ESGE classification, compared with the ASRM classification, significantly increased the frequency of septate uterus recognition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The further development of foraminoscopes with larger working channels and high speed burrs to remove bone more efficiently, along with recognition of foraminal pathoanatomy in the foramen, led to the identification and treatment of other painful degenerative conditions of the lumbar spine such as failed back surgery syndrome, recurrent disc herniations, lateral foraminal stenosis, degenerative spondylolisthesis, and isthmic spondylolisthesis. A summary of the endoscopic techniques currently used and trademarked by the author as the YESS technique include: (1) a published protocol for optimal needle and instrument placement calculated by lines drawn on the skin from the C-arm image; (2) evocative chromodiscography by the operating surgeon with nonionic radiologic contrast and indigo carmine dye to confirm concordant pain production and to stain tissue in contact with the injectate; (3) selective endoscopic discectomy, which targets the removal of loose degenerative nucleus stained differentially by indigo carmine dye; (4) thermal annuloplasty, a visualized radiofrequency thermal modulation of disc and annular defects guided by vital tissue staining; (5) endoscopic foraminoplasty, a decompression of the lateral and subarticular recess, including disc and foraminal degenerative and isthmic spondylolisthesis; (6) visually and radiologically guided exploration of the epidural space; (7) probing the hidden zone of MacNab for normal nerves (and branches of spinal nerves known as furcal nerves) versus anomalous autonomic nerves in the foramen; and (8) a uniportal and biportal technique for inside-out removal of extruded and sequestered nucleus pulposus. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using the variability of test thresholds, we used the hierarchical summary receiver operating characteristic (HSROC) model for all eligible tests (except the circulating cathodic antigen (CCA) POC for S. mansoni, where the bivariate random‐effects model was more appropriate). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…They walked for miles into Hungary, where they found shelter in a convent for several weeks. …”
Enlace del recurso
Enlace del recurso

“…We assessed—at the population level—whether and to what extent mass HIV treatment is associated with changes in sex disparities in adult life expectancy, a summary metric of survival capturing mortality across the full cascade of HIV care. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Meanwhile, hKLK1 could attenuate the cell apoptosis in CC of aged rat. In summary, our results suggest that hKLK1 may improve penile erectile function in the aged rat via activating eNOS/NO/cGMP and COX2/cAMP pathways and anti-tissue fibrosis as well as anti-apoptosis effect.…”
Enlace del recurso
Enlace del recurso

“…Such analyses provided data far beyond traditional adherence summary statistics and may form the foundation of future personalized predictive interventions to drive longitudinal adherence and support optimal self-management in chronic diseases such as diabetes.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…STUDY QUESTION: Could drugs targeting ATP-sensitive K(+) (K(ATP)) channels prevent any spontaneous increase in intracellular Ca(2+) that may occur in human metaphase II (MII) oocytes under in vitro conditions? SUMMARY ANSWER: Pinacidil, a K(ATP) channel opener, and glibenclamide, a K(ATP) channel blocker, prevent a spontaneous increase in intracellular Ca(2+) in human MII oocytes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These findings suggested that the flavonoids from clove could potentially be considered as UV-B protectants and can be explored further for its topical application to the area of the skin requiring protection. SUMMARY: Pretreatment of human dermal fibroblast with flavonoid-enriched fraction of Eugenia caryophylata attenuated effects of ultraviolet-B radiations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…STUDY QUESTION: Are significant abnormalities in outward (K(+)) conductance and resting membrane potential (V(m)) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success? SUMMARY ANSWER: Negligible outward conductance (≈5% of patients) or an enhanced inward conductance (≈4% of patients), both of which caused depolarization of V(m), were associated with a low rate of fertilization following IVF. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…STUDY QUESTION: What are the effects of fertility education on knowledge, childbearing desires and anxiety? SUMMARY ANSWER: Providing fertility information contributed to greater knowledge, but increased anxiety. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Finally, there were no studies about Africans in this meta-analysis. In summary, the results of our meta-analysis suggest an increased risk role of the MDM2 SNP T309G in renal cancer. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…STUDY QUESTION: What are the primary causes of severe male factor infertility? SUMMARY ANSWER: Although 40% of all patients showed primary causes of infertility, which could be subdivided into three groups based on the severity of their effect, ~75% of oligozoospermia cases remained idiopathic. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…STUDY QUESTION: Has there been any influence of the Zika virus (ZIKV) outbreak on the sales of contraceptive methods in Brazil? SUMMARY ANSWER: Contraceptive sales in the 24 months of evaluation showed little variation and no significant change has been observed since the ZIKV outbreak. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…By activating or repressing the genes involved in cell proliferation, growth suppression, DNA damage/repair, apoptosis/autophagy, angiogenesis, estrogen signaling, neurogenesis, synaptogenesis, and senescence, and inducing a wide range of DNA damage, genomic instability and DNA methylation and transcriptional repression, NRF1 may act as a major regulator of EEDs-induced brain health deficits. In summary, estrogenic endocrine disrupting chemicals-modified genes in brain health deficits are part of both estrogen and NRF1 signaling pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, comprehensive studies should be carried out to establish the suitability of Pluronic F127 as a carrier for other drugs with similar challenges as TQ. SUMMARY: There is a rising interest in integrating nanotechnology with medicine, creating a nanomedicine aiming for high efficiency and efficacy of disease diagnosis and treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Pooled analyses were performed in order to estimate summary age-standardized rates of TBI YLLs. In order to evaluate the relative importance of TBI in the context of all injuries, proportions of TBI YLLs out of overall injury YLLs were calculated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: The present study describes rutamarin-induced apoptosis in the HT29 cell line for the first time and suggests that rutamarin has the potential to be developed as an anticancer agent. SUMMARY: Rutamarin was cytotoxic to HT29 colon cancer cells but exerted no damage to normal colon cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PLAIN ENGLISH SUMMARY: Researchers who conduct studies in health and social care are encouraged to involve the public as early as possible in the process of designing their studies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, more research is needed into their efficacy and safety in this vulnerable population. In summary, we are still at the beginning of research on trauma and PTSD in children and adolescents. …”
Enlace del recurso
Enlace del recurso