“…STUDY QUESTION: Is periconceptional maternal smoking associated with embryonic morphological development in ongoing pregnancies? SUMMARY ANSWER: Smoking during the periconceptional period is associated with a delayed embryonic morphological development which is not fully recuperated beyond the first trimester of pregnancy. …”
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“…Other outcomes included seizures, EEG abnormalities, and MRI findings. Summary data from published RCTs were pooled through fixed-effect meta-analysis. …”
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“…SIMPLE SUMMARY: The number of growing antral follicles visualised by ultrasound generates an antral follicle count (AFC), which can predict the number of female gametes remaining in an animal’s ovary. …”
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“…SIMPLE SUMMARY: Patients with de novo metastatic (M1) nasopharyngeal carcinoma (NPC) at presentation is a heterogeneous group of the population who have a diverse range of survival. …”
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“…SIMPLE SUMMARY: Three different murine glioma cell lines were modified to downregulate the expression of the murine LDH-A gene using shRNA knock-down (KD), and compared to shRNA scrambled control (NC) cell lines. …”
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“…STUDY QUESTION: Is the embryo transfer (ET) method associated with maternal and perinatal outcomes after minimal stimulation IVF using clomiphene citrate (CC)? SUMMARY ANSWER: The incidence of pregnancy complications and adverse perinatal outcomes was influenced by the developmental stage (cleavage versus blastocyst stages) and cryopreservation (fresh versus vitrified) of the transferred embryos. …”
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“…STUDY QUESTION: What are the patient-reported outcomes (PROs) and patient-reported experiences (PREs) in home-based monitoring compared to those in hospital-based monitoring of ovulation for scheduling frozen–thawed embryo transfer (FET)? SUMMARY ANSWER: Women undergoing either home-based or hospital-based monitoring experience an increase in anxiety/sadness symptoms over time, but women undergoing home-based monitoring felt more empowered during the treatment and classified the monitoring as more discreet compared to hospital-based monitoring. …”
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“…SIMPLE SUMMARY: Calcium electroporation (CaEP) is an innovative anti-tumor treatment modality that induces cell death by introducing supraphysiological concentrations of calcium into cells with a limited effect on normal cells. …”
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“…STUDY QUESTION: Does diet-induced weight loss improve semen parameters, and are these possible improvements maintained with sustained weight loss? SUMMARY ANSWER: An 8-week low-calorie diet-induced weight loss was associated with improved sperm concentration and sperm count, which were maintained after 1 year in men who maintained weight loss. …”
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“…STUDY QUESTION: How does hormonal contraceptive use and menstrual cycle phase affect the female microbiome across different body sites? SUMMARY ANSWER: The menstrual cycle phase, but not hormonal contraceptive use, is associated with the vaginal and oral but not the gut microbiome composition in healthy young women. …”
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“…STUDY QUESTION: Are there differences in thyroid function between adolescents and young adults conceived with and without ART? SUMMARY ANSWER: This study demonstrated no evidence of clinically relevant differences in thyroid function between adolescents and young adults conceived with and without ART. …”
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“…SIMPLE SUMMARY: Skeletal disorders and related-welfare complications are an ongoing concern for rapid-growing broiler chickens. …”
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“…SIMPLE SUMMARY: Membrane feeding assays have been widely used in malaria transmission research and insectary colony maintenance. …”
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“…STUDY QUESTION: How does the human embryo breach the endometrial epithelium at implantation? SUMMARY ANSWER: Embryo attachment to the endometrial epithelium promotes the formation of multinuclear syncytiotrophoblast from trophectoderm, which goes on to breach the epithelial layer. …”
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“…The proteins responsible for transferase activity, transferring acyl groups, histone acetyltransferase activity, and microtubule binding were highly enriched, indicating that O-GlcNAc proteins play important roles in cells. In summary, this work developed an approach to enrich O-GlcNAc peptides precisely in metabolic labeling by removing cysteine thiol-azidosugar artificial modification with MSH. …”
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“…STUDY QUESTION: Can we develop an IVF prediction model to estimate individualized chances of a live birth over multiple complete cycles of IVF in couples embarking on their second complete cycle of treatment? SUMMARY ANSWER: Yes, our prediction model can estimate individualized chances of cumulative live birth over three additional complete cycles of IVF. …”
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“…STUDY QUESTION: What is the effect of the ketone β-hydroxybutyrate (βOHB) on preimplantation mouse embryo development, metabolism, epigenetics and post-transfer viability? SUMMARY ANSWER: In vitro βOHB exposure at ketogenic diet (KD)-relevant serum concentrations significantly impaired preimplantation mouse embryo development, induced aberrant glycolytic metabolism and reduced post-transfer fetal viability in a sex-specific manner. …”
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“…SIMPLE SUMMARY: High heat load (HL) can adversely affect livestock health and cause significant production losses as a result of alterations of many physiological functions including nutrient metabolism, oxidative status, blood constituent levels, and gut dysbiosis. …”
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“…SIMPLE SUMMARY: As an important energy feed material for livestock and poultry, corn is often in short supply and used immediately after harvest. …”
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“…SIMPLE SUMMARY: Since the irruption of PARPi in the therapeutic armamentarium for ovarian cancer, concerns regarding post-progression treatment outcomes have emerged, owing to known crossed-resistance mechanisms between PARPi and platinum. …”
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