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  1. 41
    “…To date, mutations in genes KISS1, KISS1R, MKRN3, DLK1 have been described as causal variants leading to precocious hypothalamic-pituitary axis activation in childhood. …”
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    Гонадотропинзависимое преждевременное половое развитие: молекулярно-генетические и клинические характеристики
  2. 42
    “…A gain of expression in the kisspeptin gene (KISS1), gain-of-function mutation in the kisspeptin receptor gene (KISS1R), loss-of-function mutation in makorin ring finger protein 3 (MKRN3), and loss-of-function mutations in the delta-like homolog 1 gene (DLK1) have been associated with ICPP. …”
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    Genetic factors in precocious puberty
  3. 43
    por Alghamdi, Ahmed
    Publicado 2023
    “…CPP may occur as genetic alterations, such as MKRN3, DLK1, or KISS1;as a part of mutations in the epigenetic factors that regulate the HPG axis, such as Lin28b and let-7; or as a part of syndromes, central lesions such as hypothalamic hamartoma, and others. …”
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    Precocious Puberty: Types, Pathogenesis and Updated Management
  4. 44
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    The Epidemiology of Young People’s Work and Experiences of Violence in Nine Countries: Evidence from the Violence against Children Surveys
  5. 45
    por Bajpai, Anurag, Menon, P. S. N
    Publicado 2011
    “…The identification of critical role of KISS-1-kisspeptin-GPR54 system has gone a long way to provide an insight into pubertal physiology. …”
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    Contemporary issues in precocious puberty
  6. 46
    “…We identified rare and novel variants in genes (37 families with 39 individuals) known to be involved in one or more of the following—midline development and/or pituitary development or function (BMP4, CDON, GLI2, GLI3, HESX1, KIAA0556, LHX9, NKX2-1, PROP1, PTCH1, SHH, TBX19, TGIF1), syndromic and non-syndromic forms of hypogonadotropic hypogonadism (CCDC141, CHD7, FANCA, FANCC, FANCD2, FANCE, FANCG, IL17RD, KISS1R, NSMF, PMM2, SEMA3E, WDR11), syndromic forms of short stature (FGFR3, NBAS, PRMT7, RAF1, SLX4, SMARCA2, SOX11), cerebellum atrophy with optic anomalies (DNMT1, NBAS), axonal migration (ROBO1, SLIT2), and agenesis of the corpus callosum (ARID1B, CC2D2A, CEP120, CSPP1, DHCR7, INPP5E, VPS13B, ZNF423). …”
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    Pituitary stalk interruption syndrome is characterized by genetic heterogeneity
  7. 47
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    Human CRMP4 mutation and disrupted Crmp4 expression in mice are associated with ASD characteristics and sexual dimorphism
  8. 48
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    Human trafficking and violence: Findings from the largest global dataset of trafficking survivors
  9. 49
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    What factors are associated with recent intimate partner violence? findings from the WHO multi-country study on women's health and domestic violence
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