Unravelling actionable biology using transcriptomic data to integrate mitotic index and Ki-67 in the management of lung neuroendocrine tumors

por Manem, Venkata S.K., Sazonova, Olga, Gagné, Andréanne, Orain, Michèle, Khoshkrood-Mansoori, Babak, Gaudreault, Nathalie, Bossé, Yohan, Joubert, Philippe
Publicado 2021

Testosterone deficiency in men receiving immunotherapy for malignant melanoma

por Peters, Madeline, Pearlman, Amy, Terry, William, Mott, Sarah L., Monga, Varun
Publicado 2021

GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growth

por Koo, Junghui, Wang, Xuerong, Owonikoko, Taofeek K., Ramalingam, Suresh S., Khuri, Fadlo R., Sun, Shi-Yong
Publicado 2021

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study

por Romano, Francesco Jacopo, Barbato, Carmela, Biglietto, Maria, Di Lauro, Vincenzo, Arundine, Dario, Fiorentino, Roberto, Ambrosio, Francesca, Cammarota, Maresa, Chiurazzi, Bruno, Puglia, Livio, Scagliarini, Sarah, Ruocco, Raffaella, Mocerino, Carmen, Cerillo, Ivana, Brangi, Maria Fiorella, Riccardi, Ferdinando
Publicado 2021

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers

por Pidkovka, Nataliya, Rachkevych, Olena, Belkhiri, Abbes
Publicado 2021

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration

por Perez, Thomas, Bergès, Raphaël, Maccario, Hélène, Oddoux, Sarah, Honoré, Stéphane
Publicado 2021

Correction: Comparison of the expression and function of Lin28A and Lin28B in colon cancer

por Wang, Tianzhen, He, Yan, Zhu, Yuanyuan, Chen, Mingwei, Weng, Mingjiao, Yang, Chao, Zhang, Yan, Ning, Ning, Zhao, Ran, Yang, Weiwei, Jin, Yinji, Li, Jing, Redpath, Riju James Rajkumar Ezakiel, Zhang, Lei, Jin, Xiaoming, Zhong, Zhaohua, Zhang, Fengmin, Wei, Yunwei, Shen, Guomin, Wang, Dong, Liu, Ying, Wang, Guangyu, Li, Xiaobo
Publicado 2021

Quercetin shortened survival of radio-resistant B-1 cells in vitro and in vivo by restoring miR15a/16 expression

por Ramos, Yasmim Alefe Leuzzi, Souza, Olivia Fonseca, Novo, Marilia Campos Tavares, Guimarães, Caroline Ferreira Cunha, Popi, Ana Flavia
Publicado 2021

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2

por Zhang, Yin-Ling, Xue, Geng, Miao, Hui, Zhou, Chuan-Chuan, Sun, Shu-Han, Zhang, Yi
Publicado 2021

Intratumoral immunotherapy with STING agonist, ADU-S100, induces CD8+ T-cell mediated anti-tumor immunity in an esophageal adenocarcinoma model

por Zaidi, Ali H., Kelly, Ronan J., Gorbunova, Anastasia, Omstead, Ashten N., Salvitti, Madison S., Zheng, Ping, Kosovec, Juliann E., Lee, Soyoung, Ayazi, Shahin, Babar, Laila, Finley, Gene G., Goel, Ajay, Jobe, Blair A.
Publicado 2021

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors

por Takebe, Naoko, Coyne, Geraldine O'Sullivan, Kummar, Shivaani, Collins, Jerry, Reid, Joel M., Piekarz, Richard, Moore, Nancy, Juwara, Lamin, Johnson, Barry C., Bishop, Rachel, Lin, Frank I., Mena, Esther, Choyke, Peter L., Lindenberg, M. Liza, Rubinstein, Larry V., Bonilla, Cecilia Monge, Goetz, Matthew P., Ames, Matthew M., McGovern, Renee M., Streicher, Howard, Covey, Joseph M., Doroshow, James H., Chen, Alice P.
Publicado 2021

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer

por Matsumura, Shuichi, Nakamori, Mikihito, Tsuji, Toshiaki, Kato, Tomoya, Nakamura, Masaki, Ojima, Toshiyasu, Fukuhara, Hiroshi, Ino, Yasushi, Todo, Tomoki, Yamaue, Hiroki
Publicado 2021

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells

por Lewis, Andrew Henry, Bridges, Cory Seth, Punia, Viraaj Singh, Cooper, Abraham Fausto Jornada, Puppi, Monica, Lacorazza, H. Daniel
Publicado 2021

The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma

por Tokuda, Kazunori, Morine, Yuji, Miyazaki, Katsuki, Yamada, Shinichiro, Saito, Yu, Nishi, Masaaki, Tokunaga, Takuya, Ikemoto, Tetsuya, Imura, Satoru, Shimada, Mitsuo
Publicado 2021

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer

por Sninsky, Jared A., Bishnupuri, Kumar S., González, Iván, Trikalinos, Nikolaos A., Chen, Ling, Dieckgraefe, Brian K.
Publicado 2021

Data driven precision medicine: who is the driver?

por Klein, Sebastian, Büttner, Reinhard
Publicado 2021

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach

por Carcereny, Enric, Fernández-Nistal, Alonso, López, Araceli, Montoto, Carmen, Naves, Andrea, Segú-Vergés, Cristina, Coma, Mireia, Jorba, Guillem, Oliva, Baldomero, Mas, Jose Manuel
Publicado 2021

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy

por Kumara, H.M.C. Shantha, Sutton, Elie, Caballero, Otavia L., Su, Tao, Yan, Xiaohong, Ahmed, Aqeel, Herath, Sonali A.C., Cekic, Vesna, Njoh, Linda, Kirchoff, Daniel D., Whelan, Richard L.
Publicado 2021

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells

por Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Jain, Preetesh, Manshouri, Taghi, Veletic, Ivo, Ferrajoli, Alessandra, Bose, Prithviraj, Thompson, Phillip, Jain, Nitin, Verstovsek, Srdan, Wierda, William, Keating, Michael J., Estrov, Zeev
Publicado 2021

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians

por Guibon, Julie, Sugier, Pierre-Emmanuel, Kulkarni, Om, Karimi, Mojgan, Bacq-Daian, Delphine, Besse, Céline, Boland, Anne, Adjadj, Elisabeth, Rachédi, Frédérique, Rubino, Carole, Xhaard, Constance, Mulot, Claire, Laurent-Puig, Pierre, Guizard, Anne-Valérie, Schvartz, Claire, Ortiz, Rosa Maria, Ren, Yan, Ostroumova, Evgenia, Deleuze, Jean-François, Boutron-Ruault, Marie-Christine, Kesminiene, Ausrele, De Vathaire, Florent, Guénel, Pascal, Lesueur, Fabienne, Truong, Thérèse
Publicado 2021