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4201por Atorrasagasti, Catalina, Peixoto, Estanislao, Aquino, Jorge B., Kippes, Néstor, Malvicini, Mariana, Alaniz, Laura, Garcia, Mariana, Piccioni, Flavia, Fiore, Esteban J., Bayo, Juan, Bataller, Ramón, Guruceaga, Elizabeth, Corrales, Fernando, Podhajcer, Osvaldo, Mazzolini, Guillermo“…Moreover, TGF-β1 expression levels were down-regulated in the liver as well as in the serum of TAA-treated knock-out animals. Ingenuity Pathway Analysis (IPA) analysis suggested several gene networks which might involve protective mechanisms of SPARC deficiency against liver fibrogenesis and a better established machinery to repair DNA and detoxify from external chemical stimuli. …”
Publicado 2013
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4202por Li, Yuejin, Liu, Na, Huang, Damao, Zhang, Zhenlin, Peng, Zhengke, Duan, Chaojun, Tang, Xiaowei, Tan, Gongjun, Yan, Guangrong, Mei, Wenhua, Tang, Faqing“…DNP also increased the expression of secretory AKR1B10, cathepsin B and clusterin 6-10B cells. Gene Ontology and Ingenuity Pathway analysis showed that DNP may regulate protein synthesis, cellular movement, lipid metabolism, molecular transport, cellular growth and proliferation signaling pathways. …”
Publicado 2012
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4203por Jensen, Kirsty, Günther, Juliane, Talbot, Richard, Petzl, Wolfram, Zerbe, Holm, Schuberth, Hans-Joachim, Seyfert, Hans-Martin, Glass, Elizabeth J“…The most affected network identified by Ingenuity Pathway analysis has the immunosuppressor transforming growth factor beta 1 (TGFB1) at its hub and largely consists of genes more highly expressed in control quarters from S. aureus infected cows. …”
Publicado 2013
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4204por Alvarado, Sebastian, Tajerian, Maral, Millecamps, Magali, Suderman, Mathew, Stone, Laura S, Szyf, Moshe“…Changes in gene expression occurred across a number of functional gene clusters encoding cardinal biological processes as revealed by Ingenuity Pathway Analysis. Significantly altered biological processes included neurological disease, skeletal muscular disorders, behavior, and psychological disorders. …”
Publicado 2013
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4205por Laugel-Haushalter, Virginie, Paschaki, Marie, Thibault-Carpentier, Christelle, Dembelé, Doulaye, Dollé, Pascal, Bloch-Zupan, Agnès“…A bioinformatics tool (Ingenuity Pathway Analysis) used to analyze biological functions and pathways on the group of incisor versus molar differentially expressed genes revealed that 143 genes belonged to 9 networks with intermolecular connections. …”
Publicado 2013
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4206por Campos-Melo, Danae, Droppelmann, Cristian A, He, Zhongping, Volkening, Kathryn, Strong, Michael J“…We observed that the majority of dysregulated miRNAs are down-regulated in sALS SC tissues. Ingenuity Pathway Analysis (IPA) showed that dysregulated miRNAs are linked with nervous system function and cell death. …”
Publicado 2013
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4207por Buro, Christin, Oliveira, Katia C., Lu, Zhigang, Leutner, Silke, Beckmann, Svenja, Dissous, Colette, Cailliau, Katia, Verjovski-Almeida, Sergio, Grevelding, Christoph G.“…The obtained data were evaluated by Gene Ontology (GO) and Ingenuity Pathway Analysis (IPA), but also by manual classification and intersection analyses. …”
Publicado 2013
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4208por Salomon, Carlos, Ryan, Jennifer, Sobrevia, Luis, Kobayashi, Miharu, Ashman, Keith, Mitchell, Murray, Rice, Gregory E.“…Protein function and canonical pathways were identified using the PANTHER program and Ingenuity Pathway Analysis, respectively. Exo-pMSC were identified, by electron microscopy, as spherical vesicles, with a typical cup-shape and diameters around of 100 nm and positive for exosome markers: CD63, CD9 and CD81. …”
Publicado 2013
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4209por PACURARI, MARICICA, ADDISON, JOSEPH B., BONDALAPATI, NAVEEN, WAN, YING-WOOI, LUO, DAJIE, QIAN, YONG, CASTRANOVA, VINCENT, IVANOV, ALEXEY V., GUO, NANCY LAN“…The miR-200 family and these potential targets are functionally involved in canonical pathways of immune response, molecular mechanisms of cancer, metastasis signaling, cell-cell communication, proliferation and DNA repair in Ingenuity pathway analysis (IPA). These results indicate that re-expression of miR-200 downregulates our previously identified NSCLC prognostic biomarkers in metastatic NSCLC cells. …”
Publicado 2013
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4210por Bassim, Carol W, Ambatipudi, Kiran S., Mays, Jacqueline W., Edwards, Dean A., Swatkoski, Stephan, Fassil, Helen, Baird, Kristin, Gucek, Marjan, Melvin, James E., Pavletic, Steven Z.“…LC-MS/MS was used to identify salivary proteins, followed by Ingenuity Pathway Analysis (IPA). Selected mass spectrometric findings, including lactotransferrin, lactoperoxidase, and albumin, were confirmed by targeted label-free quantification. …”
Publicado 2012
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4211“…The cut-offs were established empirically through ontological and semantic enrichment; resultant shortened gene list was re-expanded by Ingenuity Pathway Assistant tool. The resulting sub-networks provided the basis for generating mechanistic hypotheses that were partially validated by literature search. …”
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4212“…All proteins were subjected to Ingenuity Pathway Analysis (IPA) to create 13 biological networks and 17 pathways of interacting protein clusters in human ortholog. …”
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4213por Thirunavukkarasu, M, Addya, S, Juhasz, B, Pant, R, Zhan, L, Surrey, S, Maulik, G, Menon, V P, Maulik, N“…To get insight into the underlying molecular pathways involved in ischaemic PC, we determined the distinct and overlapping biological processes using Ingenuity pathway analysis tool. Independent evidence at the mRNA level supporting the Affymetrix results were validated using real-time RT-PCR for selected down-regulated genes, which are thought to play important roles in cardioprotection after ischaemic insult. …”
Publicado 2008
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4214por Janssen, Sarah F, Gorgels, Theo GMF, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur AB“…Functional annotations were performed with the Ingenuity knowledge database. RESULTS: We built a molecular model of AH production by combining previously published physiological data with our current genomic expression data. …”
Publicado 2013
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4215por Than, B. L. N, Goos, J. A. C. M., Sarver, A. L., O’Sullivan, M. G., Rod, A., Starr, T. K., Fijneman, R. J. A., Meijer, G. A., Zhao, L, Zhang, Y, Largaespada, D. A., Scott, P. M., Cormier, R. T.“…Pathway analysis using Ingenuity Pathway Analysis (IPA) and gene set enrichment analysis (GSEA) confirmed the importance of these gene clusters and further identified significant overlap with genes regulated by MUC2 and CFTR, two important regulators of intestinal homeostasis. …”
Publicado 2013
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4216por Zaravinos, Apostolos, Lambrou, George I., Mourmouras, Nikos, Katafygiotis, Patroklos, Papagregoriou, Gregory, Giannikou, Krinio, Delakas, Dimitris, Deltas, Constantinos“…Many of them were located within cytogenetic regions that were previously reported to be significantly aberrated. miRNA targets were predicted using the miRWalk algorithm and ingenuity pathway analysis identified the canonical pathways and curated networks of the deregulated miRNAs. …”
Publicado 2014
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4217por Kolacinska, Agnieszka, Morawiec, Jan, Fendler, Wojciech, Malachowska, Beata, Morawiec, Zbigniew, Szemraj, Janusz, Pawlowska, Zofia, Chowdhury, Dipanjan, Choi, Young Eun, Kubiak, Robert, Pakula, Lukasz, Zawlik, Izabela“…The Wilcoxon signed-rank test was used to compare related samples. Ingenuity pathway analysis was used to evaluate potential functional significance of differentially expressed miRNAs. …”
Publicado 2014
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4218por Yang, Ming, Eyers, Fiona, Xiang, Yang, Guo, Man, Young, Ian G., Rosenberg, Helene F., Foster, Paul S.“…Furthermore, by applying miRanda and Ingenuity Pathways Analysis (IPA), we identified 13 specific miRNAs that are temporally associated with the expression of IL-5Rα and CCR3 and 14 miRNAs associated with the transcription factors GATA-1/2, PU.1 and C/EBPε. …”
Publicado 2014
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4219“…Candidate genes positively regulated by unliganded GR were identified, classified by Gene Ontology and Ingenuity Pathway Analysis, and validated using quantitative real-time reverse transcriptase PCR. …”
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4220por Balacescu, Ovidiu, Balacescu, Loredana, Tudoran, Oana, Todor, Nicolae, Rus, Meda, Buiga, Rares, Susman, Sergiu, Fetica, Bogdan, Pop, Laura, Maja, Laura, Visan, Simona, Ordeanu, Claudia, Berindan-Neagoe, Ioana, Nagy, Viorica“…Primary biopsies harvested prior to therapy were analyzed for whole human gene expression (Agilent) based on the patient’s 6 months clinical response. Ingenuity Pathway Analysis was used to investigate the altered molecular function and canonical pathways between the responding and non-responding patients. …”
Publicado 2014
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