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  1. 4381
    “…Obtained list of 1348 transcripts (2.0%) that passed the filter criteria was further analyzed by Ingenuity Pathway Analysis software, identifying 735 unique differentially expressed genes (DEGs). …”
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    Atherosclerosis Pathways are Activated in Pericoronary Adipose Tissue of Patients with Coronary Artery Disease
  2. 4382
    “…Using analysis software such as Ingenuity Pathway Analysis (IPA), we were able to establish that high concentrations of FFA affected the expression of genes mainly related to glucose and insulin homoeostasis, fatty acid metabolism, as well as steroidogenesis and granulosa cell differentiation processes. …”
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    Gene cascade analysis in human granulosa tumor cells (KGN) following exposure to high levels of free fatty acids and insulin
  3. 4383
    “…Based on the biomarkers being significantly up- or down-regulated in cross-sectional and paired analysis, related canonical pathways and cellular functions were explored by Ingenuity Pathway Analysis (IPA). RESULTS: The well-studied sJIA biomarkers, IL6, IL18 and S100A12, were confirmed to be increased during active sJIA as compared to healthy controls. …”
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    Immunoprofiling of active and inactive systemic juvenile idiopathic arthritis reveals distinct biomarkers: a single-center study
  4. 4384
    “…Differentially expressed proteins were identified, and Ingenuity Pathway Analysis was conducted for the functional annotation of these proteins. …”
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    Urinary Proteomics Analysis of Active Vitiligo Patients: Biomarkers for Steroid Treatment Efficacy Prediction and Monitoring
  5. 4385
    “…Gene interaction pathways of the differentially expressed genes and miRNA-mRNA regulation were analyzed using the Ingenuity Pathway Analysis software. Four differentially expressed genes and one miRNA were further confirmed using RT-qPCR. …”
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    Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease: miRNA and mRNA Regulation
  6. 4386
    “…Differentially expressed genes (DEG) within outcome groups were identified by Significance Analysis of Microarrays and used for Hierarchical Clustering, Principal Component Analysis, and Ingenuity Pathways Analysis. RESULTS: HIV-1 replication resulted in > 3000 DEG involving 27 perturbed pathways. …”
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    Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana
  7. 4387
    “…METHODS: We obtained RNA expression data and clinical information for BRCA and normal samples from public databases and downloaded a lipid metabolism-related gene set. Ingenuity Pathway Analysis (IPA) was applied to identify the potential pathways and functions of Differentially Expressed Genes (DEGs) related to lipid metabolism. …”
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    Development and Validation of a Prognostic Classifier Based on Lipid Metabolism-Related Genes for Breast Cancer
  8. 4388
    por Brunori, Maurizio
    Publicado 2022
    “…It is a twenty pages complete paper touching all aspects of the struggle of Italian scientists to work in the “curious amalgam of ingenuity and muddle, a reflection of the political system”. …”
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    Eraldo Antonini Lectures, 1983–2019
  9. 4389
    “…We performed meta-analysis consisting of 155 tumor samples compared against 185 adjacent non-tumor samples and analyzed results with ingenuity pathway analysis. RESULTS: Our analysis revealed liver X receptors/retinoid X receptor (RXR) activation and farnesoid X receptor/RXR activation as top canonical pathways amongst others. …”
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    Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data
  10. 4390
    “…In addition, RNA sequencing and ingenuity pathway analysis were employed to investigate gene expression profiles in the hippocampi of experimental animals. …”
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    Enhanced delivery of a low dose of aducanumab via FUS in 5×FAD mice, an AD model
  11. 4391
    “…METHODS: The Prague-Dawley rats were randomly divided into sepsis (n = 6) or sham (n = 6) groups, and then the whole brain tissue was dissected at 24 h after surgery for further protein identification by Quantitative iTRAQ LC-MS/MS Proteomics. Ingenuity pathway analysis, Gene ontology knowledgebase, and STRING database are used to explore the biological significance of proteins with altered concentration. …”
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    Identification of biomarkers and therapeutic targets related to Sepsis-associated encephalopathy in rats by quantitative proteomics
  12. 4392
    “…We performed whole transcriptome microarray analysis of mouse liver tissue (C57BL/6 J) 48 h after whole-body irradiation with 1, 2, 4, 8, and 12 Gray to identify significant expression changes in mRNAs, lncRNAs, and miRNAs, We also validated changes in specific RNAs through qRT-PCR. We used Ingenuity Pathway Analysis (IPA) to identify pathways associated with gene expression changes. …”
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    Microarray analysis identifies coding and non-coding RNA markers of liver injury in whole body irradiated mice
  13. 4393
    por Vivier, Alain, Lopez, Gérald
    Publicado 2016
    “…Cet ouvrage et les codes associés s’adressent aux utilisateurs de sources de rayonnements ionisants : techniciens, ingénieurs de sécurité, personnes compétentes en radioprotection, mais aussi médecins, chercheurs, concepteurs, décideurs… Les contraintes croissantes liées à la radioprotection rendent indispensables l’utilisation de codes de calcul permettant d’évaluer les débits de doses générées par ces sources et la façon dont on peut s’en protéger au mieux. …”
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    Calculs de doses générées par les rayonnements ionisants: principes physiques et codes de calcul
  14. 4394
    “…Based on the Dep and CgP separately compared with the ReP, differentially expressed genes and signaling pathways were analyzed using GO, KEGG databases, and Ingenuity Pathway Analysis (IPA). The results and validation were obtained by immunofluorescence staining and RT-PCR assays. …”
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    Transcriptome landscape comparison of periodontium in developmental and renewal stages
  15. 4395
    “…Bioinformatic analysis with Ingenuity Pathway Analysis predicted “Creb signaling in Neurons” and “IGF-1 signaling” among the most downregulated pathways by all doses of KTZ and DES before puberty, and “PPARg” as a common upstream regulator driving gene expression changes. …”
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    Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats
  16. 4396
    “…The proteins associated with at a p value of < 0.1 were queried in the ingenuity pathway analysis (IPA) software to identify interaction networks, signaling, and metabolic pathways. …”
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    Protein biomarkers of disease progression in patients with systemic sclerosis associated interstitial lung disease
  17. 4397
    “…Pathway enrichment analysis was performed with ingenuity pathway analysis (IPA). We compared the results obtained by SOMNiBUS and bumphunter. …”
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    Novel insights into systemic sclerosis using a sensitive computational method to analyze whole-genome bisulfite sequencing data
  18. 4398
    “…Functional pathways analysis was subsequently performed on resulting gene expression values with Ingenuity Pathways Analysis (Qiagen). RESULTS: Differential LIN28B expression was demonstrated across cell lines, with DMG cells expressing greater LIN28B gene and protein levels compared to controls. …”
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    DIPG-01. LIN28B EXPRESSION IN DIFFUSE MIDLINE GLIOMA
  19. 4399
    “…Therefore, RNA-seq, metabolomic, Ingenuity Pathway Analysis, and Kyoto Encyclopedia of Genes and Genomes analyses were performed on the entire brain to investigate physiological changes in the brain, finding that glycolysis-driven ATP production was enhanced and ß-oxidation and the tricarboxylic acid cycle were downregulated in response to predation stress. …”
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    Novel predator-induced phenotypic plasticity by hemoglobin and physiological changes in the brain of Xenopus tropicalis
  20. 4400
    “…Biological relationships between significantly altered protein abundances were analysed using Ingenuity Pathways Analysis software, and receiver operator characteristic curves were calculated. …”
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    Characterizing the urinary proteome of prematurity-associated lung disease in school-aged children
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