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1041por Yang, Ziyi, Peng, Chengxin, Meng, Ruijin, Zu, Lianhai, Feng, Yutong, Chen, Bingjie, Mi, Yongli, Zhang, Chi, Yang, Jinhu“…Herein, we propose an ingenious and effective strategy for constructing hybrid-crystal-phase TiO(2)/covalent organic framework (HCPT@COF) composites where hybrid anatase/rutile TiO(2) nanodots (10 nm) are uniformly embedded in the interlayers of porous COFs. …”
Publicado 2019
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1042“…Genome-wide DNA methylation profiling was conducted in women with (n = 12) or without (n = 12) GDM using the Illumina Infinium HumanMethylationEPIC BeadChip array. Functional analysis of differentially methylated genes was conducted using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses. …”
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1043“…The C-C σ-bond activation of unstrained cycloketones represents an ingenious and advanced technique in synthetic chemistry, but it remains a challenging area which has been largely underexplored. …”
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1044“…Pro-inflammatory M1 macrophages play an important role in defence. However, ingenious pathogen survival mechanisms including phagolysosome destruction enable their persistence. …”
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1045por Wei, Jie, Wang, Huimin, Gong, Xue, Wang, Qing, Wang, Hong, Zhou, Yangjie, Wang, Fuan“…The construction of robust, modular and compact DNA machinery facilitates us to build more intelligent and ingenious sensing strategies in complex biological systems. …”
Publicado 2020
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1046“…Forty-three cats were genotyped on the Illumina Infinium Feline 63K iSelect DNA Array and used for analyses. …”
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1047“…Establishing latent infection but retaining the capability to reactivate in certain circumstance is an ingenious tactic for retroviruses to persist in vivo while evading host immune surveillance. …”
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1048por Chimalapati, Suneeta, de Souza Santos, Marcela, Lafrance, Alexander E, Ray, Ann, Lee, Wan-Ru, Rivera-Cancel, Giomar, Vale, Gonçalo, Pawlowski, Krzysztof, Mitsche, Matthew A, McDonald, Jeffrey G, Liou, Jen, Orth, Kim“…This study reveals the resourcefulness of microbes and the interplay between virulence systems and host cell resources to evolve an ingenious scheme for survival and escape.…”
Publicado 2020
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1049por Gupta, Praveen Kumar, Arif, Mohammad, Shaik, Likhita, Singh, Romil, Shah, Kaushal“…This case report summarizes this ingenious depiction of a partial third nerve palsy presenting as the sole sign of the epidural hemorrhage in a cognizant patient.…”
Publicado 2020
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1050por Milutin Gašperov, Nina, Sabol, Ivan, Božinović, Ksenija, Dediol, Emil, Mravak-Stipetić, Marinka, Licastro, Danilo, Dal Monego, Simeone, Grce, Magdalena“…In this study, 32 oral samples were tested: nine healthy oral mucosae, 13 HNSCC, and 10 oral lesions for DNA methylation by the Infinium MethylationEPIC BeadChip. Our findings showed that a panel of genes significantly hypermethylated in their promoters or specific sites in HNSCC samples in comparison to healthy oral samples, which are mainly oncogenes, receptor, and transcription factor genes, or genes included in cell cycle, transformation, apoptosis, and autophagy. …”
Publicado 2020
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1051por Thurakkal, Liya, Singh, Satyam, Roy, Rajarshi, Kar, Parimal, Sadhukhan, Sushabhan, Porel, Mintu“…The emerging paradigm shift from ‘one molecule, one target, for one disease’ towards ‘multi-targeted small molecules’ has paved an ingenious pathway in drug discovery in recent years. …”
Publicado 2021
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1052por Minorsky, Peter V.“…These ideas were based on highly sensitive measurements he made of various plant functions by means of assorted ingenious instruments of his own design. Despite being the most internationally celebrated plant biologist of the early 20(th) century, by the end of his life, Bose had become a scientific pariah whose work was expunged from Western histories of plant biology for nearly a century. …”
Publicado 2020
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1053por Li, Xin, Ouyang, Zhijun, Li, Helin, Hu, Chaolei, Saha, Pabitra, Xing, Lingxi, Shi, Xiangyang, Pich, Andrij“…Here, the PAMAM dendrimer decorated PVCL-GMA nanogels (NGs) were developed for favorable biodistribution in vivo and enhanced antitumor efficacy of ovarian carcinoma. By an ingenious design, the NGs with a unique structure that GMA-rich domains were localized on the surface were synthesized via precipitation polymerization. …”
Publicado 2021
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1054por Christiansen, Steffan Noe, Jacobsen, Stine Bøttcher, Andersen, Jeppe Dyrberg, Kampmann, Marie-Louise, Trudsø, Linea Christine, Olsen, Kristine Boisen, Tfelt-Hansen, Jacob, Banner, Jytte, Morling, Niels“…We assessed DNA methylation of more than 850,000 positions in cardiac tissue from nine SUD and 14 SUDEP cases using the Illumina Infinium MethylationEPIC BeadChip. In total, six differently methylated regions (DMRs) between the SUD and SUDEP cases were identified. …”
Publicado 2021
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1055“…Simple limbal epithelial transplantation (SLET) is an ingenious, low cost and effective technique of limbal stem cell transplantation (LSCT) that is increasingly being undertaken in practice across the world. …”
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1056por Imm, Jennifer, Pishva, Ehsan, Ali, Muhammadd, Kerrigan, Talitha L., Jeffries, Aaron, Burrage, Joe, Glaab, Enrico, Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Lunnon, Katie“…In the present study, induced pluripotent stem cell colonies (33Qn1 line) were differentiated and collected at four time-points, with DNA methylation assessed using the Illumina Infinium Human Methylation EPIC BeadChip array. Dynamic changes in DNA methylation occurring during differentiation were investigated using a data-driven trajectory inference method. …”
Publicado 2021
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1057por Zhao, Yuan, Li, Bo, Li, Cuicui, Xu, Yangfan, Luo, Yi, Liang, Dongwu, Huang, Chongxing“…Edible packaging is a sustainable product and technology that uses one kind of “food” (an edible material) to package another kind of food (a packaged product), and organically integrates food with packaging through ingenious material design. Polysaccharides are a reliable source of edible packaging materials with excellent renewable, biodegradable, and biocompatible properties, as well as antioxidant and antimicrobial activities. …”
Publicado 2021
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1058por Chang, Meiqi, Feng, Wei, Ding, Li, Zhang, Hongguang, Dong, Caihong, Chen, Yu, Shi, Jianlin“…Herein, aiming at the dual purposes of reducing biological toxicity induced by long-term light irradiation and alleviating hypoxia, we here introduce a novel-designed CaAl(2)O(4):Eu,Nd blue persistent luminescence material (PLM) as the in vivo light source after pre-excited in vitro. The ingenious construction of blue-emitting PLM with “optical battery” characteristics activates cyanobacterial cells and verteporfin simultaneously, which performs the successive oxygen supply and singlet oxygen generation without the long-term external excitation, resulting in the modulated tumor hypoxic microenvironment and enhanced photodynamic tumor proliferation inhibition efficiency. …”
Publicado 2021
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1059“…With tailorable compositions and properties, polymers facilitate the ingenious design of various polymeric nanostructures. …”
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1060por Xiong, Lulu, Zhang, Yuanyuan, Wu, Shiming, Chen, Feng, Lei, Lingli, Yu, Ling, Li, Changming“…A facile and ingenious method to chemical etching-coordinating a metal-organic framework (MOF) followed by an annealing treatment was proposed to prepare Co(3)O(4) nanoparticles uniformly dispersed in rational porous carbon nano-boxes (Co(3)O(4)@CNBs), which was further used to detect H(2)O(2) released from living cells. …”
Publicado 2022
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