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1321por Cotton, Allison M., Price, E. Magda, Jones, Meaghan J., Balaton, Bradley P., Kobor, Michael S., Brown, Carolyn J.“…We examined the interplay of DNA methylation (DNAm) with CpG density, transcriptional activity and chromatin state at genes on the X chromosome using over 1800 female samples analysed with the Illumina Infinium Human Methylation450 BeadChip. DNAm was used to predict an inactivation status for 63 novel transcription start sites (TSSs) across 27 tissues. …”
Publicado 2015
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1322por Lu, Tzu-Pin, Hsiao, Chuhsing K, Lai, Liang-Chuan, Tsai, Mong-Hsun, Hsu, Chung-Ping, Lee, Jang-Ming, Chuang, Eric Y“…Thirty-two pairs of tumor and adjacent normal lung tissue specimens were analyzed using Affymetrix U133plus2.0, Affymetrix SNP 6.0, and Illumina Infinium Methylation microarrays. Copy number variations (CNVs) and methylation alterations were analyzed and paired t-tests were used to identify differentially expressed genes. …”
Publicado 2015
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1323por Nazarenko, Maria S., Markov, Anton V., Lebedev, Igor N., Freidin, Maxim B., Sleptcov, Aleksei A., Koroleva, Iuliya A., Frolov, Aleksei V., Popov, Vadim A., Barbarash, Olga L., Puzyrev, Valery P.“…So far, our current knowledge of the DNA methylation profiles for atherosclerosis affected and healthy human vascular tissues is still limited. Using the Illumina Infinium Human Methylation27 BeadChip, we performed a genome-wide analysis of DNA methylation in right coronary artery in the area of advanced atherosclerotic plaques, atherosclerotic-resistant internal mammary arteries, and great saphenous veins obtained from same patients with coronary heart disease. …”
Publicado 2015
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1324“…The tool can be used to display phenotype association signals and correlation patterns of microarray or sequencing-based DNA methylation data, such as Illumina Infinium 450k, WGBS, or MeDIP-seq, as well as other types of genomic data, such as gene expression profiles. …”
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1325por Huang, Yen-Tsung, Maccani, Jennifer Z.J., Hawley, Nicola L., Wing, Rena R., Kelsey, Karl T., McCaffery, Jeanne M.“…This study examined peripheral blood mononuclear cell (PBMC) methylation patterns in NW (n=16, current/lifetime BMI 18.5-24.9) and OB individuals (n=16, current BMI≥30), and SWLM (n=16, current BMI 18.5-24.9, lifetime maximum BMI ≥30, average weight loss 57.4 lbs) using an Illumina Infinium HumanMethylation450 BeadArray. No leukocyte population-adjusted epigenome-wide analyses were significant; however, potentially differentially methylated loci across groups were observed in RYR1 (p=1.54E-6), MPZL3 (p=4.70E-6), and TUBA3C (p=4.78E-6). …”
Publicado 2014
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1326por Vandiver, Amy R, Irizarry, Rafael A, Hansen, Kasper D, Garza, Luis A, Runarsson, Arni, Li, Xin, Chien, Anna L, Wang, Timothy S, Leung, Sherry G, Kang, Sewon, Feinberg, Andrew P“…RESULTS: We compare epidermis and dermis of both sun-protected and sun-exposed skin derived from younger subjects (under 35 years old) and older subjects (over 60 years old), using the Infinium HumanMethylation450 array and whole genome bisulfite sequencing. …”
Publicado 2015
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1327por Danielsson, Anna, Nemes, Szilárd, Tisell, Magnus, Lannering, Birgitta, Nordborg, Claes, Sabel, Magnus, Carén, Helena“…RESULTS: Methylation data generated by the Illumina Infinium HumanMethylation 450 BeadChip arrays were downloaded from the Gene Expression Omnibus (n = 472). …”
Publicado 2015
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1328por Binder, Alexandra M., LaRocca, Jessica, Lesseur, Corina, Marsit, Carmen J., Michels, Karin B.“…RESULTS: To assess the mechanistic aspects of fetal programming, we measured genome-wide methylation (Infinium HumanMethylation450 BeadChips) and expression (Affymetrix transcriptome microarrays) in placental tissue of 41 GDM cases and 41 matched pregnancies without maternal complications from the Harvard Epigenetic Birth Cohort. …”
Publicado 2015
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1329por Das, Mithun, Irvin, M. Ryan, Sha, Jin, Aslibekyan, Stella, Hidalgo, Bertha, Perry, Rodney T., Zhi, Degui, Tiwari, Hemant K., Absher, Devin, Ordovas, Jose M., Arnett, Donna K.“…A total of 443 individuals were studied for epigenome-wide changes in DNA methylation, assessed using the Illumina Infinium HumanMethylation450 array, before and after a 3-week daily treatment with 160 mg of fenofibrate. …”
Publicado 2015
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1330por Massa, Alicia N., Manrique-Carpintero, Norma C., Coombs, Joseph J., Zarka, Daniel G., Boone, Anne E., Kirk, William W., Hackett, Christine A., Bryan, Glenn J., Douches, David S.“…The 156 F(1) progeny and parents of a cross (MSL603) between “Jacqueline Lee” and “MSG227-2” were genotyped using the Infinium 8303 Potato Array. Furthermore, the progeny and parents were evaluated for foliar late blight reaction to isolates of the US-8 genotype of Phytophthora infestans (Mont.) de Bary and vine maturity. …”
Publicado 2015
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1331por Zhang, Min, Zhang, Shaojun, Wen, Yanhua, Wang, Yihan, Wei, Yanjun, Liu, Hongbo, Zhang, Dongwei, Su, Jianzhong, Wang, Fang, Zhang, Yan“…We explored DNA methylation patterns in association with gene expression to assess their impact on the prognosis of breast cancer based on Infinium 450K arrays (training set) from The Cancer Genome Atlas (TCGA). …”
Publicado 2015
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1332por Oros Klein, Kathleen, Grinek, Stepan, Bernatsky, Sasha, Bouchard, Luigi, Ciampi, Antonio, Colmegna, Ines, Fortin, Jean-Philippe, Gao, Long, Hivert, Marie-France, Hudson, Marie, Kobor, Michael S., Labbe, Aurelie, MacIsaac, Julia L., Meaney, Michael J., Morin, Alexander M., O’Donnell, Kieran J., Pastinen, Tomi, Van Ijzendoorn, Marinus H., Voisin, Gregory, Greenwood, Celia M.T.“…We therefore present a new R package for normalization of data from the Illumina Infinium Human Methylation450 BeadChip (Illumina 450 K) built on the concepts in the recently published funNorm method, and introducing cell-type or tissue-type flexibility. …”
Publicado 2016
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1333por Xu, Liping, Hu, Kaining, Zhang, Zhenqian, Guan, Chunyun, Chen, Song, Hua, Wei, Li, Jiana, Wen, Jing, Yi, Bin, Shen, Jinxiong, Ma, Chaozhi, Tu, Jinxing, Fu, Tingdong“…Genotyping was performed with a Brassica 60K Illumina Infinium SNP array. A total of 41 single-nucleotide polymorphisms (SNPs) distributed on 14 chromosomes were found to be associated with flowering time, and 12 SNPs located in the confidence intervals of quantitative trait loci (QTL) identified in previous researches based on linkage analyses. …”
Publicado 2016
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1334por Shih, Yu-Lueng, Kuo, Chih-Chi, Yan, Ming-De, Lin, Ya-Wen, Hsieh, Chung-Bao, Hsieh, Tsai-Yuan“…Recently, we discovered numerous novel genes that were aberrantly methylated in hepatocellular carcinoma (HCC) by using Infinium HumanMethylation27 BeadChip array. We utilized a quantitative methylation-specific PCR (Q-MSP) system for the evaluation of PAX6 methylation in 29 normal controls and 160 paired HCC tissues and their adjacent non-tumor tissues. …”
Publicado 2016
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1335por Manunza, A., Cardoso, T. F., Noce, A., Martínez, A., Pons, A., Bermejo, L. A., Landi, V., Sànchez, A., Jordana, J., Delgado, J. V., Adán, S., Capote, J., Vidal, O., Ugarte, E., Arranz, J. J., Calvo, J. H., Casellas, J., Amills, M.“…A total of 141 individuals were genotyped with the Infinium 50 K Ovine SNP BeadChip (Illumina). We combined this dataset with Spanish ovine data previously reported by the International Sheep Genomics Consortium (N = 229). …”
Publicado 2016
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1336por Shavrukov, Yuri“…For example, SNP markers based on high-throughput technology (Infinium or KASP) are very effective and useful in both barley and bread wheat. …”
Publicado 2016
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1337por Houseman, E. Andres, Kile, Molly L., Christiani, David C., Ince, Tan A., Kelsey, Karl T., Marsit, Carmen J.“…We demonstrate these methods in an analysis of 23 Infinium data sets from 13 distinct data collection efforts; these empirical evaluations show that our algorithm can reasonably estimate the number of constituent types, return cell proportion estimates that demonstrate anticipated associations with underlying phenotypic data; and methylomes that reflect the underlying biology of constituent cell types. …”
Publicado 2016
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1338por Sun, Chengming, Wang, Benqi, Yan, Lei, Hu, Kaining, Liu, Sheng, Zhou, Yongming, Guan, Chunyun, Zhang, Zhenqian, Li, Jiana, Zhang, Jiefu, Chen, Song, Wen, Jing, Ma, Chaozhi, Tu, Jinxing, Shen, Jinxiong, Fu, Tingdong, Yi, Bin“…This population contains 476 inbred lines representing the major Chinese rapeseed genepool and 44 lines from other countries. The 60K Brassica Infinium® SNP array was utilized to genotype the association panel. …”
Publicado 2016
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1339por Yue, Weihua, Cheng, Weiqiu, Liu, Zhaorui, Tang, Yi, Lu, Tianlan, Zhang, Dai, Tang, Muni, Huang, Yueqin“…The DNA methylation was examined at over 485,000 CpG sites using the Illumina Infinium Human Methylation450 BeadChip. As a result, 8,417 probes corresponding to 2,190 unique genes were found to be differentially methylated between OCD and healthy control subjects. …”
Publicado 2016
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1340por Wu, Jian, Zhao, Qing, Liu, Sheng, Shahid, Muhammad, Lan, Lei, Cai, Guangqin, Zhang, Chunyu, Fan, Chuchuan, Wang, Youping, Zhou, Yongming“…In the present study, a genome-wide association study (GWAS) for SSR resistance in B. napus were performed using an association panel of 448 accessions genotyped with the Brassica 60K Infinium(®) single-nucleotide polymorphism (SNP) array. …”
Publicado 2016
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