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1601por Ohara, Kentaro, Arai, Eri, Takahashi, Yoriko, Ito, Nanako, Shibuya, Ayako, Tsuta, Koji, Kushima, Ryoji, Tsuda, Hitoshi, Ojima, Hidenori, Fujimoto, Hiroyuki, Watanabe, Shun-ichi, Katai, Hitoshi, Kinoshita, Takayuki, Shibata, Tatsuhiro, Kohno, Takashi, Kanai, Yae“…We analyzed single-institutional methylome data by single-CpG-resolution Infinium assay for 1007 samples of non-cancerous tissue (N) and corresponding cancerous tissue (T) obtained from lung, stomach, kidney, breast and liver. …”
Publicado 2017
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1602por Henneman, Peter, Bouman, Arjan, Mul, Adri, Knegt, Lia, van der Kevie-Kersemaekers, Anne-Marie, Zwaveling-Soonawala, Nitash, Meijers-Heijboer, Hanne E. J., van Trotsenburg, A. S. Paul, Mannens, Marcel M.“…Epigenetic profiles were obtained from extracted DNA using the Illumina Infinium 450K array. Since aberrant blood cell distribution is known to be present in DS, we applied two distinct models: with and without correction for estimated blood cell distribution. …”
Publicado 2018
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1603por Miyake, Kunio, Kawaguchi, Akio, Miura, Ryu, Kobayashi, Sachiko, Tran, Nguyen Quoc Vuong, Kobayashi, Sumitaka, Miyashita, Chihiro, Araki, Atsuko, Kubota, Takeo, Yamagata, Zentaro, Kishi, Reiko“…We examined the effects of maternal smoking on DNA methylation in cord blood, in 247 mother–infant pairs in the Sapporo cohort of the Hokkaido Study, using the Infinium HumanMethylation 450K BeadChip. We first identified differentially methylated CpG sites with a false discovery rate (FDR) of <0.05 and the magnitude of DNA methylation changes (|β| >0.02) from the pairwise comparisons of never-smokers (Ne-S), sustained-smokers (Su-S), and stopped-smokers (St-S). …”
Publicado 2018
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1604por Xu, Song-Song, Gao, Lei, Xie, Xing-Long, Ren, Yan-Ling, Shen, Zhi-Qiang, Wang, Feng, Shen, Min, Eyϸórsdóttir, Emma, Hallsson, Jón H., Kiseleva, Tatyana, Kantanen, Juha, Li, Meng-Hua“…To explore genetic mechanisms underlying the variation in litter size, we conducted multiple independent genome-wide association studies in five sheep breeds of high prolificacy (Wadi, Hu, Icelandic, Finnsheep, and Romanov) and one low prolificacy (Texel) using the Ovine Infinium HD BeadChip, respectively. We identified different sets of candidate genes associated with litter size in different breeds: BMPR1B, FBN1, and MMP2 in Wadi; GRIA2, SMAD1, and CTNNB1 in Hu; NCOA1 in Icelandic; INHBB, NF1, FLT1, PTGS2, and PLCB3 in Finnsheep; ESR2 in Romanov and ESR1, GHR, ETS1, MMP15, FLI1, and SPP1 in Texel. …”
Publicado 2018
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1605por Grindler, N. M., Vanderlinden, L., Karthikraj, R., Kannan, K., Teal, S., Polotsky, A. J., Powell, T. L., Yang, I. V., Jansson, T.“…We determined epigenome-wide DNA methylation marks (Illumina Infinium Human Methylation 850k BeadChip) and gene expression (Agilent whole human genome array) associated with phthalate exposure in first trimester placenta. …”
Publicado 2018
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1606“…A longitudinal methylomic study was conducted using Infinium HumanMethylation450 BeadChip covering half a million cytosine–phosphate–guanine (CpG) sites across the human genome from whole-blood samples. …”
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1607por Chen, Lunlin, Wan, Heping, Qian, Jiali, Guo, Jianbin, Sun, Chengming, Wen, Jing, Yi, Bin, Ma, Chaozhi, Tu, Jinxing, Song, Laiqiang, Fu, Tingdong, Shen, Jinxiong“…A total of 419 B. napus accessions and inbred lines were genotyped with a 60K Illumina Infinium SNP array of Brassica. Wide genotypic variations in Cd concentration and translocation were found. …”
Publicado 2018
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1608Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosispor Karouzakis, Emmanuel, Raza, Karim, Kolling, Christoph, Buckley, Christopher D., Gay, Steffen, Filer, Andrew, Ospelt, Caroline“…DNA was hybridized to Infinium Human methylation 450k and 850k arrays and differential methylated genes and pathways were identified. …”
Publicado 2018
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1609por Kthiri, Dhouha, Loladze, Alexander, MacLachlan, P. R., N’Diaye, Amidou, Walkowiak, Sean, Nilsen, Kirby, Dreisigacker, Susanne, Ammar, Karim, Pozniak, Curtis J.“…Bulked segregant analysis using the Infinium iSelect 90K single nucleotide polymorphism (SNP) array identified two genomic regions for leaf rust resistance; one on chromosome 6BS for Geromtel_3 and Tunsyr_2 and the other on chromosome 7BL for Amria and Byblos. …”
Publicado 2018
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1610por Sun, Zhengwen, Li, Hanli, Zhang, Yan, Li, Zhikun, Ke, Huifeng, Wu, Liqiang, Zhang, Guiyin, Wang, Xingfen, Ma, Zhiying“…In this study, we evaluated two salt-tolerance-related traits of a natural population comprising 713 upland cotton (Gossypium hirsutum L.) accessions worldwide at the seedling stage and performed a genome-wide association study (GWAS) to identify marker-trait associations under salt stress using the Illumina Infinium CottonSNP63K array. A total of 23 single nucleotide polymorphisms (SNPs) that represented seven genomic regions on chromosomes A01, A10, D02, D08, D09, D10, and D11 were significantly associated with the two salt-tolerance-related traits, relative survival rate (RSR) and salt tolerance level (STL). …”
Publicado 2018
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1611por Schoeler, Natasha E., Leu, Costin, Balestrini, Simona, Mudge, Jonathan M., Steward, Charles A., Frankish, Adam, Leung, Mary‐Anne, Mackay, Mark, Scheffer, Ingrid, Williams, Ruth, Sander, Josemir W., Cross, J. Helen, Sisodiya, Sanjay M.“…Genotyping was performed with the Infinium HumanOmniExpressExome Beadchip. Hospital records were used to obtain demographic and clinical data. …”
Publicado 2018
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1612por Bortoluzzi, Andressa, Salum, Giovanni Abrahão, da Rosa, Eduarda Dias, Chagas, Vinicius de Saraiva, Castro, Mauro Antônio Alves, Manfro, Gisele Gus“…DNA methylation was evaluated with the Infinium HumanMethylation450 BeadChip from saliva samples collected at both evaluations. …”
Publicado 2018
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1613por Seaborne, R. A., Strauss, J., Cocks, M., Shepherd, S., O’Brien, T. D., Someren, K. A. van, Bell, P. G., Murgatroyd, C., Morton, J. P., Stewart, C. E., Mein, C. A., Sharples, A. P.“…DNA methylation is an important epigenetic modification that can regulate gene expression following environmental encounters without changes to the genetic code. Using Infinium MethylationEPIC BeadChip Arrays (850,000 CpG sites) we analysed for the first time, DNA isolated from untrained human skeletal muscle biopsies (vastus lateralis) at baseline (rest) and immediately following an acute (single) bout of resistance exercise. …”
Publicado 2018
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1614por García-Calzón, Sonia, Perfilyev, Alexander, de Mello, Vanessa D, Pihlajamäki, Jussi, Ling, Charlotte“…PARTICIPANTS/INTERVENTION: We analyzed DNA methylation with the Infinium HumanMethylation450 BeadChip in liver of an obese population (34 males, 61 females). …”
Publicado 2018
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1615“…Improving molecular understanding of the involved factors and pathways would improve obesity phenotype characterization and reveal potentially relevant targets for obesity intervention. The Illumina Infinium HumanMethylation450 BeadChip was used in a leucocyte epigenome-wide association study (EWAS) to quantify differential DNA methylation in 60 lean compared with 60 obese young women. …”
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1616por Salomon, Matthew P., Orozco, Javier I. J., Wilmott, James S., Hothi, Parvinder, Manughian-Peter, Ayla O., Cobbs, Charles S., Scolyer, Richard A., Hoon, Dave S. B., Marzese, Diego M.“…Using the widely employed Illumina Infinium HumanMethylation 450K platform, we have generated a cohort of genome-wide DNA methylomes from ninety-six needle-dissected BM specimens from patients with lung cancer, breast cancer, and cutaneous melanoma with clinical, pathological, and demographic annotations. …”
Publicado 2018
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1617por García-Solano, José, Turpin, María C., Torres-Moreno, Daniel, Huertas-López, Francisco, Tuomisto, Anne, Mäkinen, Markus J., Conesa, Ana, Conesa-Zamora, Pablo“…The methylation status of 450,000 CpG sites using the Infinium Human Methylation 450 BeadChip array was investigated in 48 colorectal specimens, including 39 SACs and 9 matched hmMSI-H. …”
Publicado 2018
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1618por N’Diaye, Amidou, Haile, Jemanesh K., Nilsen, Kirby T., Walkowiak, Sean, Ruan, Yuefeng, Singh, Asheesh K., Clarke, Fran R., Clarke, John M., Pozniak, Curtis J.“…For this study, 192 durum wheat lines were genotyped using the Illumina 90K Infinium iSelect assay, and resulted in a total of 14,324 polymorphic SNPs. …”
Publicado 2018
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1619por James, Philip, Sajjadi, Sara, Tomar, Ashutosh Singh, Saffari, Ayden, Fall, Caroline H D, Prentice, Andrew M, Shrestha, Smeeta, Issarapu, Prachand, Yadav, Dilip Kumar, Kaur, Lovejeet, Lillycrop, Karen, Silver, Matt, Chandak, Giriraj R“…Finally, we compile all candidate genes and regions of interest identified in the searches and describe their genomic locations, annotations and coverage on the Illumina Infinium Methylation beadchip arrays. RESULTS: We summarize findings from the 34 studies found in the first search, the 31 studies found in the second search and the eight studies found in the third search. …”
Publicado 2018
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1620por Brumano, Larissa Pereira, da Silva, Francisco Vitor Santos, Costa-Silva, Tales Alexandre, Apolinário, Alexsandra Conceição, Santos, João Henrique Picado Madalena, Kleingesinds, Eduardo Krebs, Monteiro, Gisele, Rangel-Yagui, Carlota de Oliveira, Benyahia, Brahim, Junior, Adalberto Pessoa“…Consequently, in accordance with Quality-by-Design (QbD) principles, ingenious new products tailored to minimize adverse reactions while increasing patient survival have been devised. …”
Publicado 2019
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