Chemerin Elicits Potent Constrictor Actions via Chemokine‐Like Receptor 1 (CMKLR1), not G‐Protein‐Coupled Receptor 1 (GPR1), in Human and Rat Vasculature

por Kennedy, Amanda J., Yang, Peiran, Read, Cai, Kuc, Rhoda E., Yang, Lucy, Taylor, Emily J. A., Taylor, Colin W., Maguire, Janet J., Davenport, Anthony P.
Publicado 2016

Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites

por Williams, Thomas L., Strachan, Gregory, Macrae, Robyn G. C., Kuc, Rhoda E., Nyimanu, Duuamene, Paterson, Anna L., Sinha, Sanjay, Maguire, Janet J., Davenport, Anthony P.
Publicado 2021

Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function

por Nyimanu, Duuamene, Chapman, Fiona A., Gallacher, Peter J., Kuc, Rhoda E., Williams, Thomas L., Newby, David E., Maguire, Janet J., Davenport, Anthony P., Dhaun, Neeraj
Publicado 2022

[Pyr(1)]Apelin-13((1–12)) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr(1)]Apelin-13

por Yang, Peiran, Kuc, Rhoda E., Brame, Aimée L., Dyson, Alex, Singer, Mervyn, Glen, Robert C., Cheriyan, Joseph, Wilkinson, Ian B., Davenport, Anthony P., Maguire, Janet J.
Publicado 2017

The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo

por Read, Cai, Nyimanu, Duuamene, Yang, Peiran, Kuc, Rhoda E., Williams, Thomas L., Fitzpatrick, Christopher M., Foster, Richard, Glen, Robert C., Maguire, Janet J., Davenport, Anthony P.
Publicado 2021

Evaluating the implementation of a national disclosure policy for large-scale adverse events in an integrated health care system: identification of gaps and successes

por Maguire, Elizabeth M., Bokhour, Barbara G., Wagner, Todd H., Asch, Steven M., Gifford, Allen L., Gallagher, Thomas H., Durfee, Janet M., Martinello, Richard A., Elwy, A. Rani
Publicado 2016

International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Pe...

por Read, Cai, Nyimanu, Duuamene, Williams, Thomas L., Huggins, David J., Sulentic, Petra, Macrae, Robyn G. C., Yang, Peiran, Glen, Robert C., Maguire, Janet J., Davenport, Anthony P.
Publicado 2019

Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr(1)]apelin-13 in humans

por Nyimanu, Duuamene, Kay, Richard G., Sulentic, Petra, Kuc, Rhoda E., Ambery, Philip, Jermutus, Lutz, Reimann, Frank, Gribble, Fiona M., Cheriyan, Joseph, Maguire, Janet J., Davenport, Anthony P.
Publicado 2019

Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19

por Abraham, George R., Kuc, Rhoda E., Althage, Magnus, Greasley, Peter J., Ambery, Philip, Maguire, Janet J., Wilkinson, Ian B., Hoole, Stephen P., Cheriyan, Joseph, Davenport, Anthony P.
Publicado 2022

Children and parents’ perspectives on the acceptability of three management strategies for dental caries in primary teeth within the ‘Filling Children’s Teeth: Indicated or Not’ (F...

por El-Yousfi, Sarab, Innes, Nicola P. T., Holmes, Richard D., Freeman, Ruth, Cunningham, Kathryn B., McColl, Elaine, Maguire, Anne, Douglas, Gail V. A., Clarkson, Janet E., Marshman, Zoe
Publicado 2020

Risk Communication After Health Care Exposures: An Experimental Vignette Survey With Patients

por Elwy, A. Rani, Maguire, Elizabeth M., Gallagher, Thomas H., Asch, Steven M., Durfee, Janet M., Martinello, Richard A., Bokhour, Barbara G., Gifford, Allen L., Taylor, Thomas J., Wagner, Todd H.
Publicado 2021

Elucidating knowledge and beliefs about obesity and eating disorders among key stakeholders: paving the way for an integrated approach to health promotion

por Bullivant, Bianca, Denham, Aaron R., Stephens, Clare, Olson, Rebecca E., Mitchison, Deborah, Gill, Timothy, Maguire, Sarah, Latner, Janet D., Hay, Phillipa, Rodgers, Bryan, Stevenson, Richard J., Touyz, Stephen, Mond, Jonathan M.
Publicado 2019

Dental professionals’ experiences of managing children with carious lesions in their primary teeth – a qualitative study within the FiCTION randomised controlled trial

por Marshman, Zoe, Kettle, Jennifer E., Holmes, Richard D., Cunningham, Kathryn B., Freeman, Ruth, Gibson, Barry J., McColl, Elaine, Maguire, Anne, Douglas, Gail V. A., Clarkson, Janet E., Innes, Nicola P. T.
Publicado 2020

A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development: IUPHAR Review 29

por Alexander, Steve P.H., Armstrong, Jane F., Davenport, Anthony P., Davies, Jamie A., Faccenda, Elena, Harding, Simon D., Levi‐Schaffer, Francesca, Maguire, Janet J., Pawson, Adam J., Southan, Christopher, Spedding, Michael
Publicado 2020

A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension

por Yang, Peiran, Read, Cai, Kuc, Rhoda E., Nyimanu, Duuamene, Williams, Thomas L., Crosby, Alexi, Buonincontri, Guido, Southwood, Mark, Sawiak, Stephen J., Glen, Robert C., Morrell, Nicholas W., Davenport, Anthony P., Maguire, Janet J.
Publicado 2019

Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes

por Macrae, Robyn G C, Colzani, Maria T, Williams, Thomas L, Bayraktar, Semih, Kuc, Rhoda E, Pullinger, Anna L, Bernard, William G, Robinson, Emma L, Davenport, Emma E, Maguire, Janet J, Sinha, Sanjay, Davenport, Anthony P
Publicado 2022

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulati...

por Yang, Peiran, Read, Cai, Kuc, Rhoda E., Buonincontri, Guido, Southwood, Mark, Torella, Rubben, Upton, Paul D., Crosby, Alexi, Sawiak, Stephen J., Carpenter, T. Adrian, Glen, Robert C., Morrell, Nicholas W., Maguire, Janet J., Davenport, Anthony P.
Publicado 2017

A Workshop on Measuring the Progression of Atrophy Secondary to Stargardt Disease in the ProgStar Studies: Findings and Lessons Learned

por Ervin, Ann-Margret, Strauss, Rupert W., Ahmed, Mohamed I., Birch, David, Cheetham, Janet, Ferris, Frederick L., Ip, Michael S., Jaffe, Glenn J., Maguire, Maureen G., Schönbach, Etienne M., Sadda, SriniVas R., West, Sheila K., Scholl, Hendrik P.N.
Publicado 2019

Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection

por Williams, Thomas L., Colzani, Maria T., Macrae, Robyn G. C., Robinson, Emma L., Bloor, Stuart, Greenwood, Edward J. D., Zhan, Jun Ru, Strachan, Gregory, Kuc, Rhoda E., Nyimanu, Duuamene, Maguire, Janet J., Lehner, Paul J., Sinha, Sanjay, Davenport, Anthony P.
Publicado 2021

LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal

por Shaikh, Lalarukh Haris, Zhou, Junhua, Teo, Ada E. D., Garg, Sumedha, Neogi, Sudeshna Guha, Figg, Nichola, Yeo, Giles S., Yu, Haixiang, Maguire, Janet J., Zhao, Wanfeng, Bennett, Martin R., Azizan, Elena A. B., Davenport, Anthony P., McKenzie, Grahame, Brown, Morris J.
Publicado 2015