“…BACKGROUND & OBJECTIVES: Statins are one of the most widely used drugs and have antilipidemic effects as well as antioxidant, anti-inflammatory, anti-angiogenic and anti-tumorigenic effects. …”
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“…BACKGROUND: Above and beyond their role in cardiovascular risk reduction, statins appear to have a chemopreventive role in some gastro-intestinal cancers. …”
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“…BACKGROUND: There is evidence of statin benefit among patients with diabetes regardless of cholesterol levels or prior cardiovascular disease history. …”
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“…Volitional limb motor control involves dynamic and static muscle actions. It remains elusive how such distinct actions are controlled through separated or shared neural circuits. …”
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“…The statin family of drugs are safe and effective therapeutic agents for the treatment of arteriosclerotic cardiovascular disease (CVD). …”
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“…Background and Aims: Statins are the first-line medication to treating hypercholesterolemia. …”
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“…This paper investigates how such measurements of the channel impulse response can be utilized to augment existing ultra-wideband communication and localization networks to a multi-static radar network. The approach is experimentally evaluated using off-the-shelf hardware and simple, distributed filtering, and shows that a tag-free human walking in the space equipped with ultra-wideband modules can be tracked in real time. …”
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“…Degree of floating toe syndrome was measured according to whether any toe was not in full contact with the ground in a static standing posture—the Floating Toe Point (FTP). …”
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“…BACKGROUND: The purpose of this cohort study was to investigate the independent relationship between preoperative statin therapy (PST) and postoperative severe multiorgan failure, measured by the Sequential Organ Failure Assessment (SOFA) maximum greater than 11, in high-risk patients undergoing isolated coronary artery bypass grafting (CABG). …”
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“…Patients with CAI have poor static and dynamic balance performance compared to that in healthy counterparts. …”
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“…To understand how Cottonid reacts to application-oriented mechanical loads and how it fails, development of microstructural damage on the surface and in the volume of Cottonid was studied using innovative in situ testing techniques for the first time. Quasi-static tensile tests were comparatively performed in a scanning electron microscope as well as a microfocus computer tomograph, and the development of defects present in the initial condition of the material was investigated. …”
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“…Debates on whether statin use reduces the effectiveness of influenza vaccines against critical illness and death among persons >65 years of age continue. …”
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“…Statin-induced immune-mediated necrotizing myopathy, also known as anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy, is an inflammatory myopathy that is triggered by statin exposure and persists after statin discontinuation. …”
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“…We also studied the changes in whole‐brain connectivity patterns using both static functional network connectivity (sFNC) and dynamic FNC (dFNC). …”
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“…IMPORTANCE: Statins are prescribed to help lower cholesterol levels but have poor adherence rates. …”
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“…Lipophilicity of statins has been linked to extrahepatic cell penetration and inhibition of isoprenoid synthesis and coenzyme Q10, which may affect myocardial contraction. …”
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