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35881por Cunha, Filipe M., Pereira, Joana, Marques, Pedro, Moreira, Helena, Rodrigues, Pedro, Pinto, Maria João, Lourenço, Patrícia, Bettencourt, Paulo“…Diabetics were more often discharged on ACE inhibitors/ARB, antiplatelet therapy, and statins. Neither admission nor discharge BNP values differed between diabetics and pair-matched nondiabetics. …”
Publicado 2017
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35882“…Guidelines-directed medical therapy including aspirin, statins, beta-blocker therapy, calcium channel blockers and ranolazine should be instituted for symptom and ischemia management. …”
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35883por Kobayashi, Yusuke, Kashima, Hiroyasu, Rahmanto, Yohan Suryo, Banno, Kouji, Yu, Yu, Matoba, Yusuke, Watanabe, Keiko, Iijima, Moito, Takeda, Takashi, Kunitomi, Haruko, Iida, Miho, Adachi, Masataka, Nakamura, Kanako, Tsuji, Kosuke, Masuda, Kenta, Nomura, Hiroyuki, Tominaga, Eiichiro, Aoki, Daisuke“…We have previously reported an antitumor effect of statins, antidyslipidemic drugs, on ovarian cancer in vitro and in vivo. …”
Publicado 2017
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35884por Neves, C.D.C., Lacerda, A.C.R., Lima, L.P., Lage, V.K.S., Balthazar, C.H., Leite, H.R., Mendonça, V.A.“…Moreover, heavy smokers presented lower cortisol levels in the last collection (10:00 pm) than the control group (P=0.02) and presented statically higher values of cotinine than the light smokers (P=0.002). …”
Publicado 2017
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35885“…BACKGROUND: Simvastatin belongs to the statin family, whose members have immunomodulatory activities. …”
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35886por Fernandes, Fábio, de Melo, Dirceu Thiago Pessoa, Ramires, Felix José Alvarez, Dias, Ricardo Ribeiro, Tonini, Marcio, Fernandes, Vinicius dos Santos, Rochitte, Carlos Eduardo, Moreira, Carlos Henrique Valente, Mady, Charles“…All tests were two-tailed, and an alpha error ≤ 5% was considered statically significant. RESULTS: We studied 84 patients (mean age, 44 ± 17.9 years; 67% male). …”
Publicado 2017
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35887por Leonard, Charles E., Brensinger, Colleen M., Bilker, Warren B., Kimmel, Stephen E., Whitaker, Heather J., Hennessy, Sean“…We quantified the risk of venous thromboembolism (VTE) and ischemic stroke (IS) due to statin and fibrate discontinuation in warfarin users, in which warfarin was initially dose-titrated during ongoing antihyperlipidemic therapy. …”
Publicado 2017
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35888“…Our work provides a novel mechanistic link between Aβ and the mevalonate pathway, which will impact the views on issues related to cholesterol, isoprenoids, and statins in AD. We also identify SREBP-2 as an indirect target of Akt in neurons, which may play a role in the cross-talk between AD and diabetes.…”
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35889“…Moreover, evidence suggests the use of statins in obese women with PCOS, but guidelines call for further research. …”
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35890por del Campo, José A., García-Valdecasas, Marta, Gil-Gómez, Antonio, Rojas, Ángela, Gallego, Paloma, Ampuero, Javier, Gallego-Durán, Rocío, Pastor, Helena, Grande, Lourdes, Padillo, Francisco J., Muntané, Jordi, Romero-Gómez, Manuel“…Hepatitis C virus (HCV) infection has been related to increased risk of development of hepatocellular carcinoma (HCC) while metformin (M) and statins treatment seemed to protect against HCC development. …”
Publicado 2018
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35891“…Other agents with potential immunomodulating effects, including non-immune intravenous immunoglobulin, N-acetylcysteine, acute use of statins, macrolides, pamidronate, nitazoxanide, chloroquine, antiC5a antibody, interferons, human mesenchymal stromal cells, mycophenolic acid, peroxisome proliferator-activated receptors agonists, non-steroidal anti-inflammatory agents, mesalazine, herbal medicine, and the role of plasmapheresis and hemoperfusion as rescue therapy have supportive preclinical or observational clinical data, and deserve more investigation preferably by RCTs. …”
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35892“…These substrates were either cultured statically or subjected to intermittent hydrostatic pressure at 270 kPa, 1 Hz for 60 min daily over 21 days in osteogenic medium. …”
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35893por Ahemed, Seid Adem, Denu, Zewditu Abdissa, Getinet Kassahun, Habtamu, Yilikal Fentie, Demeke“…CONCLUSION AND RECOMMENDATIONS: There was no statically significant difference between TAP and II-IH blocks regarding postoperative pain score, but the II-IH block significantly reduced the total tramadol consumption and prolonged the time to first analgesic request than TAP. …”
Publicado 2018
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35894por Kerr, Marion, Pears, Robert, Miedzybrodzka, Zofia, Haralambos, Kate, Cather, Moyra, Watson, Melanie, Humphries, Steve E.“…Patents have recently expired on high-intensity statins, reducing FH treatment costs. We build a model using UK data to estimate the cost effectiveness of DNA testing of relatives of those with monogenic FH. …”
Publicado 2017
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35895“…Connective tissue growth factor (CTGF) is a novel fibrotic mediator, which is considered to mediate fibrosis through extracellular matrix (ECM) synthesis in diabetic cardiovascular complications. Statins have significant immunomodulatory effects and reduce vascular injury. …”
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35896por Arya, Rector, Escalante, Agustin, Farook, Vidya S., Restrepo, Jose F., Battafarano, Daniel F., Almeida, Marcio, Kos, Mark Z., Fourcaudot, Marcel J., Mummidi, Srinivas, Kumar, Satish, Curran, Joanne E., Jenkinson, Christopher P., Blangero, John, Duggirala, Ravindranath, del Rincon, Inmaculada“…Strong associations were observed after adjusting for covariate effects including baseline clinical characteristics and statin use. Susceptibility loci and genes and/or nearest genes associated with CIMT in MAs and EAs with RA are presented. …”
Publicado 2018
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35897por Shen, Zhaojun, Li, Saisai, Sheng, Bo, Shen, Qi, Sun, Lu-Zhe, Zhu, Haiyan, Zhu, Xueqiong“…BACKGROUND: Medical therapeutic options remain quite limited for uterine fibroids treatment. Statins, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, have anti-tumoral effects on multiple cancer types, however, little is known about their effects on uterine fibroids. …”
Publicado 2018
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35898por Min, Jeong Jin, Shin, Byung-Seop, Lee, Jong-Hwan, Jeon, Yunseok, Ryu, Dae Kyun, Kim, Sojin, Shin, Young Hee“…Although statins have been suggested to attenuate the progression of diabetic cardiomyopathy, its effect without glycemic control remains unclear. …”
Publicado 2018
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35899“…Risk factors for overfat/obese that remained statically significant were children in urban areas (aOR = 3.19, 95% CI: 2.18−4.66, p = 0.000), being one child in a household, and parents who have diabetes mellitus. …”
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35900por Lahoz, Carlos, Castillo, Elisa, Mostaza, Jose M., de Dios, Olaya, Salinero-Fort, Miguel A., González-Alegre, Teresa, García-Iglesias, Francisca, Estirado, Eva, Laguna, Fernando, Sanchez, Vanesa, Sabín, Concesa, López, Silvia, Cornejo, Victor, de Burgos, Carmen, Garcés, Carmen“…Results: There was an inverse correlation between adherence to the Mediterranean diet and the CRP concentration, even after adjusting by age, gender, hypertension, metabolic syndrome, body mass index, statin treatment and hypertension treatment (p = 0.041). …”
Publicado 2018
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