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  1. 36201
    “…RESULTS: The constructed vector (pNZPnisA:CYTO-LLO) was expressed in L. lactis NZ9000 and was best induced at mid-log phase with 0.2% v/v nisin for 4 h statically at 30°C. Purification of the His-tagged LLO was accomplished by Ni-NTA affinity chromatography and functionality was confirmed through haemolytic assays. …”
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    Nisin inducible production of listeriolysin O in Lactococcus lactis NZ9000
  2. 36202
    “…Most patients received a statin or fibrate as lipid control medication (rosiglitazone 78%, controls 83%). …”
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    Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance
  3. 36203
    “…%ID/g MPI (.087 ± .018%) and AA5 (.03 ± .01%) uptake was higher in HC than control (n = 6) animals (.014 ± .004%, P < .0001; .0007 ± .0002%, P < .0001), and reduced substantially after diet or statin intervention. There was a significant correlation between MPI and AA5 uptake (r = .62, P < .0001), both correlated with pathologically verified MMP-9 activity, macrophage content, and TUNEL staining. …”
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    Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis
  4. 36204
    “…Lung was the commonest foci of sepsis (38.8%). 78.6% of the study population had one or more additional causal factor for rhabdomyolysis like statin intake, chronic alcoholism, hypokalemia, hypernatremia and hypophosphatemia. …”
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    Rhabdomyolysis in Community Acquired Bacterial Sepsis – A Retrospective Cohort Study
  5. 36205
    “…There were clinically significant differences between the two groups regarding sexual outcomes, but these differences were not statically significant. CONCLUSION: Postnatal sexual problems were very common after both NVD/epi and C/S. …”
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    A Comparison of Sexual Outcomes in Primiparous Women Experiencing Vaginal and Caesarean Births
  6. 36206
    “…In contrast, lowering cholesterol levels via statin treatment generated a greater response in LNCaP cells than PC-3 cells. …”
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    Cholesterol Homeostasis in Two Commonly Used Human Prostate Cancer Cell-Lines, LNCaP and PC-3
  7. 36207
    “…We explored if there were changes in commonly available markers of renal function during fenofibrate treatment in the FIELD Helsinki cohort excluding statin users. RESEARCH DESIGN AND METHODS: One hundred and seventy subjects with type 2 diabetes were randomly assigned to micronized fenofibrate (200 mg/day) or placebo for 5 years. …”
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    Effects of Long-Term Fenofibrate Treatment on Markers of Renal Function in Type 2 Diabetes: The FIELD Helsinki substudy
  8. 36208
    “…Secondary outcomes are: healthy lifestyle behaviour (with regard to smoking, physical activity, dietary pattern and compliance to statin therapy) and psychological correlates and determinants of healthy lifestyle behaviour (knowledge, attitude, risk perception, social influence, self-efficacy, cues to action, intention and autonomy). …”
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    A tailored lifestyle intervention to reduce the cardiovascular disease risk of individuals with Familial Hypercholesterolemia (FH): design of the PRO-FIT randomised controlled trial
  9. 36209
    por Banks, Kamakki, Lo, Monica, Khera, Amit
    Publicado 2010
    “…Other promising pharmacologic therapies include xanthine derivatives, estrogen replacement therapy, ACE inhibitors, and statin medications, among other emerging treatment options. …”
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    Angina in Women without Obstructive Coronary Artery Disease
  10. 36210
    “…The lumen area of the abdominal aorta increased by 4.97% per year (p = 0.002), but the carotid artery and thoracic aorta lumen areas did not change significantly. The use of statin therapy did not change the rate of increase of wall area of carotid artery, thoracic and abdominal aorta, but decreased the rate of change of lumen area of carotid artery (-3.08 ± 11.34 vs. 0.19 ± 12.91 p < 0.05). …”
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    Variations in atherosclerosis and remodeling patterns in aorta and carotids
  11. 36211
    “…Likewise, AMPK activation by pharmacological (5′-aminoimidazole-4-carboxymide-1-β-d-ribofuranoside, metformin, and statin) or genetic means (adenoviral overexpression of constitutively active AMPK mutants) significantly mitigated ER stress and SERCA oxidation and improved the endothelium-dependent relaxation in isolated mouse aortae. …”
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    Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo
  12. 36212
    “…Recent studies indicate that fibrates and statins possess anticancer potential. Fenofibrate is a potent agonist of peroxisome proliferator activated receptor alpha (PPARα) that can switch energy metabolism from glycolysis to fatty acid β-oxidation, and has low systemic toxicity. …”
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    ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARα -mediated inhibition of Glioma cell motility in vitro
  13. 36213
    “…A reduced risk of renal cell cancer among statin users has been hypothesized but has not been adequately studied. …”
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    Epidemiologic characteristics and risk factors for renal cell cancer
  14. 36214
    “…Baseline characteristics were similar among treatment groups, except for more smokers and statin users in the MT group, more hypertensives and lower LDL-cholesterol levels in the CABG group, and more angina in the PCI group at study entry. …”
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    Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery
  15. 36215
    “…The difference was statically significant CONCLUSION: In the present study, topical phenytoin accelerated healing of excisional wound in albino rats.…”
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    Evaluation of Wound Healing Effect of Topical Phenytoin on Excisional Wound in Albino Rats
  16. 36216
    “…Moderate daily doses of the statins were used, with 76% of simvastatin users taking 20 mg or less, 48% of atorvastatin users taking 10 mg, 55% of pravastatin users taking 20 mg, and 76% of rosuvastatin users taking 5 or 10 mg. …”
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    Clinical Use and Effectiveness of Lipid Lowering Therapies in Diabetes Mellitus—An Observational Study from the Swedish National Diabetes Register
  17. 36217
    “…Treatment decisions regarding statin combination therapy should take into account relevant safety concerns, i.e. the risk of elevation of blood glucose, uric acid or liver enzymes with niacin, and myopathy, increased serum creatinine and cholelithiasis with fibrates. …”
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    Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
  18. 36218
    “…The Brief Illness Perception Questionnaire (repeated for T2D, hypertension, and hyperlipidemia) and the Beliefs about Medicines Questionnaire Specific Concerns Scales (repeated for Oral hypoglycemic agents, anti-hypertensive medicines, and statins) were sent to 480 people managing co-morbid T2D. …”
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    Patient perceptions of treatment and illness when prescribed multiple medicines for co-morbid type 2 diabetes
  19. 36219
    “…None had dyslipoproteinemia or previous statin use. Total cholesterol (TC) and its fractions, inflammatory markers, and prednisone use were evaluated. …”
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    Infliximab Induces Increase in Triglyceride Levels in Psoriatic Arthritis Patients
  20. 36220
    “…Methods: Cross national retrospective observational study of utilization (DDDs – defined daily doses) and expenditure (Euros and local currency) of proton pump inhibitors (PPIs) and statins among 19 European countries and regions principally from 2001 to 2007. …”
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    Policies to Enhance Prescribing Efficiency in Europe: Findings and Future Implications
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