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  1. 36321
    “…We previously showed that treatment of Mecp2 mice with statin drugs alleviated motor symptoms and improved health and longevity. …”
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    MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex
  2. 36322
    por Miller, Joan W.
    Publicado 2016
    “…In a case study and pilot multicenter clinical trial, we observed significant regression of drusen and an improvement in visual acuity in patients taking high-dose statin therapy. These results, though preliminary, warrant further investigation. …”
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    Beyond VEGF—The Weisenfeld Lecture
  3. 36323
    “…Compared with control participants, patients with HIV had higher usage of antihypertensives (46 (63%) vs 30 (35%), p<0.001) and statins (47 (64%) vs 29 (33%), p<0.001). There was no difference in plaque distribution between both groups; however, the Gensini score was 42% lower in cases with HIV than in controls (p<0.03). …”
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    Lower coronary plaque burden in patients with HIV presenting with acute coronary syndrome
  4. 36324
    “…Calcium channel blockers and statins were less frequently used by the CS group than the non-CS group (both P < 0.05) after discharge. …”
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    Prognostic Analysis for Cardiogenic Shock in Patients with Acute Myocardial Infarction Receiving Percutaneous Coronary Intervention
  5. 36325
    “…The beneficial effect of acupuncture on the incidence of CHD was independent of age, sex, comorbidities, and statins used. CONCLUSIONS: Our study confirmed that acupuncture reduced the risk of CHD in patients with fibromyalgia in Taiwan. …”
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    Acupuncture decreased the risk of coronary heart disease in patients with fibromyalgia in Taiwan: a nationwide matched cohort study
  6. 36326
    “…Subsequently, she was advised diet modification and statin therapy with regular follow-up after every 6 months. …”
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    Low-density lipoprotein apheresis in a pediatric patient of familial hypercholesterolemia: Primi experientia from a tertiary care center in North India
  7. 36327
    por Iurlo, Alessandra, Nobili, Alessandro, Latagliata, Roberto, Bucelli, Cristina, Castagnetti, Fausto, Breccia, Massimo, Abruzzese, Elisabetta, Cattaneo, Daniele, Fava, Carmen, Ferrero, Dario, Gozzini, Antonella, Bonifacio, Massimiliano, Tiribelli, Mario, Pregno, Patrizia, Stagno, Fabio, Vigneri, Paolo, Annunziata, Mario, Cavazzini, Francesco, Binotto, Gianni, Mansueto, Giovanna, Russo, Sabina, Falzetti, Franca, Montefusco, Enrico, Gugliotta, Gabriele, Storti, Sergio, D'Addosio, Ada M., Scaffidi, Luigi, Cortesi, Laura, Cedrone, Michele, Rossi, Antonella Russo, Avanzini, Paolo, Mauro, Endri, Spadea, Antonio, Celesti, Francesca, Giglio, Gianfranco, Isidori, Alessandro, Crugnola, Monica, Calistri, Elisabetta, Sorà, Federica, Rege-Cambrin, Giovanna, Sica, Simona, Luciano, Luigiana, Galimberti, Sara, Orlandi, Ester M., Bocchia, Monica, Tettamanti, Mauro, Alimena, Giuliana, Saglio, Giuseppe, Rosti, Gianantonio, Mannucci, Pier Mannuccio, Cortelezzi, Agostino
    Publicado 2016
    “…RESULTS: Polypharmacy was reported in 107 patients (36.1%), and drugs more frequently used were antiplatelets, diuretics, proton pump inhibitors, ACE-inhibitors, beta-blockers, calcium channel blockers, angiotensin II receptors blockers, statins, oral hypoglycemic drugs and alpha blockers. …”
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    Imatinib and polypharmacy in very old patients with chronic myeloid leukemia: effects on response rate, toxicity and outcome
  8. 36328
    “…There was no significant difference in the incidence of HAP between PG and NG (25.74% versus. 24.55%, p > 0.05) and 28-day mortality (50.72% versus 58.18%, p > 0.05). However, prior statin treatment did modify the mortality of ventilator associated pneumonia (VAP) (36.54% versus 58.14%, p = 0.041) and proved to be a protective factor (HR, 0.564; 95% CI, 0.310~0.825, p = 0.038). …”
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    Effect of Prior Atorvastatin Treatment on the Frequency of Hospital Acquired Pneumonia and Evolution of Biomarkers in Patients with Acute Ischemic Stroke: A Multicenter Prospective Study
  9. 36329
    “…All seven models showed moderate C-statics ranging from 0.727 to 0.744. Following recalibration, general-FRS, simplified-FRS, CN-ICVD, PCE-white and PCE-AA had improved C-statistics of 0.776, 0.795, 0.793, 0.779, and 0.776 for men and 0.756, 0.753, 0.755, 0.758 and 0.760 for women, respectively. …”
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    Comparison of validation and application on various cardiovascular disease mortality risk prediction models in Chinese rural population
  10. 36330
    “…In addition to lifestyle modifications, specific genetic manipulations in adipose tissue and administration of PPARγ agonists or statins, have improved fat volume and phenotype, and cardiovascular failures. …”
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    Regulation of visceral and epicardial adipose tissue for preventing cardiovascular injuries associated to obesity and diabetes
  11. 36331
    “…Indeed, other studies should be initiated regarding exact molecular and cellular effects of statins in the treatment of vitiligo.…”
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    A Comparison of Betamethasone Valerate 0.1% Cream Twice Daily Plus Oral Simvastatin Versus Betamethasone Valerate 0.1% Cream Alone in the Treatment of Vitiligo Patients
  12. 36332
    por Hamada, Shota, Gulliford, Martin C.
    Publicado 2017
    “…Substantial proportions of patients were treated with antidiabetic drugs (78%), antihypertensive drugs (76%), statins (62%) and low-dose aspirin (46%) in Q1. Prescribing of these drugs slightly decreased by 3–8% in Q4. …”
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    Drug prescribing during the last year of life in very old people with diabetes
  13. 36333
    “…Background. Statins are the recently evolved agents that aid in periodontal regeneration and ultimately in attaining periodontal health. …”
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    Comparative evaluation of efficacy of subgingivally delivered 1.2% Atorvastatin and 1.2% Simvastatin in the treatment of intrabony defects in chronic periodontitis: a randomized controlled trial
  14. 36334
    “…In this study we investigated whether exerting an impulse on a Chronic Total Occlusion (CTO) improves the success rate of CTO crossing as compared to the currently used method of statically pushing the guidewire against the CTO. A prototype (Ø2 mm) was developed that generates translational momentum using a spring-loaded indenter and converts it to an impulse during impact. …”
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    Endovascular Crossing of Chronic Total Occlusions Using an Impulse: An Explorative Design Study
  15. 36335
    “…Anacetrapib reduced the VLDL-TG pool on a statin background due to an increased VLDL-TG FCR (29%; P = 0.002). …”
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    Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E
  16. 36336
    “…According to the multivariate Cox-regression analysis, demonstration of ischemia in MPS before revascularization, statin use, clopidogrel use, and higher high-density lipoprotein cholesterol levels were found to be associated with a reduced risk of ACS-related hospitalization, whereas the presence of diabetes mellitus and smoking was found to be associated with an increased risk of ACS-related hospitalization.…”
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    Demonstration of Ischemia in Myocardial Perfusion Scintigraphy before Coronary Revascularization Decreases Acute Coronary Syndrome-related Hospitalizations
  17. 36337
    “…A review of the literature suggests that patients with type 2 diabetes with low C-peptide level may be at increased risk of ketoacidosis, particularly if they are on statins and diuretics due to hypokalemia and impaired release of insulin. …”
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    Sodium–glucose cotransporter-2 inhibition and acidosis in patients with type 2 diabetes: a review of US FDA data and possible conclusions
  18. 36338
    “…Acting downstream P2X7 by MMPs inhibitors, diminished IL-1β mRNA without transcriptional effect at MMP9, possibly because the assumption of statin by patients. These data firstly demonstrated A740003 suitability as a specific tool to decrease inflammatory status in human vessels and might support the design of studies applying P2X7 antagonists for the local targeting and tailored therapy of atherosclerosis.…”
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    P2X7 receptor antagonism modulates IL-1β and MMP9 in human atherosclerotic vessels
  19. 36339
    “…The minimum time between tests that was found to give a statically significant result was in those greater than one year (P = 0.03). …”
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    Improved Hepascore in hepatitis C predicts reversal in risk of adverse outcome
  20. 36340
    “…Purpose: The pleiotropic effects of statins (antioxidant and anti-inflammation) have been reported by previous studies. …”
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    Anticonvulsant and Antioxidant Effects of Pitavastatin Against Pentylenetetrazol-Induced Kindling in Mice
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