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  1. 36701
    “…The covariates included age, sex, body mass index (BMI), dyslipidemia, statin consumption, and physical activity leisure time. …”
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    Lipoprotein Particle Profiles Associated with Telomere Length and Telomerase Complex Components
  2. 36702
    “…METHODS: Participants from EMPA-REG OUTCOME were screened for inclusion using both REDUCE-IT-like criteria (baseline statin therapy, triglycerides 135–499 mg/dL and LDL-C 41–100 mg/dL) and slightly amended FDA indication criteria (triglycerides ≥150 mg/dL). …”
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    Generalizability of REDUCE-IT eligibility criteria in a large diabetes cardiovascular outcomes trial: A post hoc subgroup analysis of EMPA-REG outcome: Analysis of EMPA-REG OUTCOME using REDUCE-IT criteria
  3. 36703
    “…With 994 participants from BioHEART-CT Discovery Cohort, we collected clinical data and performed high-performance liquid chromatography with mass spectrometry to determine concentrations of 683 plasma lipid species. Statin-naive participants were selected based on subclinical CAD (sCAD) categories as the analytical cohort (n = 580), with sCAD+ (n = 243) compared to sCAD− (n = 337). …”
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    Lipidomics Profiling and Risk of Coronary Artery Disease in the BioHEART-CT Discovery Cohort
  4. 36704
    “…This was mainly driven by an increased use of statins with 163.07%, and among these, rosuvastatin increased more than 1500-fold, and atorvastatin with 106.95% increase. …”
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    Eleven-Year Trends in Lipid-Modifying Medicines Utilisation and Expenditure in a Low-Income Country: A Study from the Republic of Srpska, Bosnia and Herzegovina
  5. 36705
    “…Postoperative urodynamic studies regarding peak urinary flow, bladder capacity, and residual urine were not statically different from the preoperative results. …”
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    Initial experience and short-term outcomes of single-port extraperitoneal transvesical robot-assisted radical prostatectomy: a two-center study
  6. 36706
    “…Clinical improvements were found to be significant for tetracyclines (−0.51 [-0.71;-0.31] p < 0.001), macrolides (−0.71 [-1.04;-0.38] p < 0.001), statins (−0.84 [-0.98;-0.70] p < 0.001), metformin (−1.47 [-1.66;-1.29] p < 0.001) and hyaluronan (−1.61 [-2.28;-0.94] p < 0.001) loaded gels, but non-significant for chlorhexidine (−0.48 [-1.10; 0.14] p = 0.13), metronidazole (−0.50 [-1.20; 0.20] p = 0.16) and bisphosphonates (−0.42 [-1.39; 0.54] p = 0.539) gels. …”
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    Gels as adjuvant to non-surgical periodontal therapy: A systematic review and meta-analysis
  7. 36707
    “…Notably, 39 (31%) patients were using statin treatment. Coronary angiography showed that 103 (82%) patients had coronary artery disease. …”
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    Is there a difference between aortic and brachial vein blood lipoprotein and total cholesterol levels?
  8. 36708
    “…When there is uncertainty about CVD risk and the net benefit of preventive pharmacotherapy interventions (such as statins), measuring a coronary artery calcium score can help further refine risk and guide shared decision-making. …”
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    A Woman’s Heart: Improving Uptake and Awareness of Cardiovascular Screening for Middle-Aged Populations
  9. 36709
    “…Traditional cardiovascular risk factors, such as smoking, diabetes mellitus, hyperlipidaemia, obesity, and hypertension, have also been linked with unfavourably altered fibrin clot properties, while some lifestyle modifications and pharmacological treatment, in particular statins and anticoagulants, may improve fibrin structure and function. …”
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    Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice
  10. 36710
    “…METHODS AND RESULTS: Serum sLOX‐1 was assessed in a case–control study in AAA (n=104) and peripheral artery disease (n=104). sLOX‐1 was not statistically different between AAA and peripheral artery disease but was higher in AAA (β=1.28, P=0.04) after adjusting for age, atherosclerosis, type 2 diabetes, prescription of statins, β‐blockers, ACE inhibitors, and therapeutic anticoagulation. sLOX‐1 was not associated with the aortic diameter, AAA volume, or the thickness of the intraluminal thrombus. …”
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    Associations of Tissue and Soluble LOX‐1 with Human Abdominal Aortic Aneurysm
  11. 36711
    por Khan, Saeed R., Canales, Benjamin K.
    Publicado 2023
    “…CONCLUSION: In addition to supersaturation-reducing therapies, the use of anti-oxidants, free radical scavengers, and inhibitors of NADPH oxidase, NLRP3 inflammasome, and RAAS may prove beneficial for stone prevention. Compounds such as statins and angiotensin converting enzyme inhibitors are already in use as therapeutics for hypertension and cardio-vascular disease and have previously shown to reduce calcium oxalate nephrolithiasis in rats. …”
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    Proposal for pathogenesis-based treatment options to reduce calcium oxalate stone recurrence
  12. 36712
    “…BACKGROUND: Lipid screening determines eligibility for statins and other cardiovascular risk reduction interventions. …”
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    Trends in Lipid Screening Among Adults in an Integrated Health Care Delivery System, 2009-2015
  13. 36713
    “…Optimal medical therapy (OMT) was defined as the presence of at least one antiplatelet agent, statin and ACE inhibitor or AT-2 antagonist based on guideline recommendations. …”
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    Impact of Optimal Medical Therapy on Reintervention and Survival Rates after Endovascular Infrapopliteal Revascularization
  14. 36714
    “…In 83.3% of children and 96.7% of adolescents, statins were the most frequently prescribed drug. …”
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    Clinical Approach in the Management of Paediatric Patients with Familial Hypercholesterolemia: A National Survey Conducted by the LIPIGEN Paediatric Group
  15. 36715
    “…In recent years, a protective effect of statin treatment on the development of heart failure in cancer patients has been observed. …”
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    Prognostic value of coronary atherosclerosis and CAC score for the risk of chemotherapy-related cardiac dysfunction (CTRCD): The protocol of ANTEC study
  16. 36716
    “…RESULTS: The results of this study show, that in the context of general general outpatient palliative care, there is a significant increase in the prescription of opioids (18.3% vs. 37.7%), sedatives (7.8% vs. 16.2%) and antiemetics (5.3% vs. 9.7%), as well as a significant reduction in other medications such as statins (21.4% vs. 11.5%), proton pump inhibitors (PPI) (41.2% vs. 35.3%), or antihypertensives (57.5% vs. 46.6%). …”
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    Drug landscape in patients receiving general outpatient palliative care in Germany: results from a retrospective analysis of 10,464 patients
  17. 36717
    “…An alarmin, interleukin (IL)-33 is a danger signal that causes inflammation, inducing chemotactic proteins such as monocyte chemoattractant protein (MCP)-1 in various cells. As statins have pleiotropic actions including anti-inflammatory properties, we investigated the effects of simvastatin on IL-33-induced MCP-1 expression in human umbilical vein endothelial cells (HUVECs). …”
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    Inhibitory Effects of Simvastatin on IL-33-Induced MCP-1 via the Suppression of the JNK Pathway in Human Vascular Endothelial Cells
  18. 36718
    “…The P-value was set as < 0.005 to be considered statically significant. RESULTS: The study included 136 homogeneous patients, with a mean ICU length of stay of 4.5 (± 4.43 day). …”
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    Perioperative risk factors impact on intensive care unit length of stay (ICU length of stay) in oral squamous cell carcinoma
  19. 36719
    “…Given this potential association, various therapeutic interventions (obeticholic acid, peroxisome proliferator-activated receptors, sodium-glucose co-transporter 2 inhibitors, glucagon-like peptide-1 receptor agonists, probiotics, synbiotics, rifaximin, vitamin E, pentoxifylline, ursodeoxycholic acid, fibroblast growth factor-21, n-3 polyunsaturated fatty acids, statins, angiotensin receptor blockers) have been evaluated for their effect on TNF-α and NAFLD. …”
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    The Role of Tumor Necrosis Factor-Alpha in the Pathogenesis and Treatment of Nonalcoholic Fatty Liver Disease
  20. 36720
    “…This is especially true for the growing number of individuals with diabetes, obesity, or the metabolic syndrome, and those on statin therapy. Most guidelines, however, continue to promote LDL-C as the primary risk marker due to uncertainty as to whether the greater accuracy of apoB is sufficient to warrant a paradigm shift. …”
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    Use of Apolipoprotein B in the Era of Precision Medicine: Time for a Paradigm Change?
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