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36881“…But once adjusted for menopause status, depressive symptoms were no longer statically associated with triglyceride component (OR = 1.20, 95% CI = 0.99–1.46, P = 0.07). …”
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36882“…Diet interventions, such as dietary fibers, polyphenols, medium-chain fatty acids, diacylglycerol, and long-chain n-3 polyunsaturated fatty acids (PUFA), ameliorate postprandial hypertriglyceridemia, moreover, drugs for dyslipidemia (n-3 PUFA, statins, fibrates or ezetimibe) and diabetes concerning incretins (dipeptidyl-peptidase IV inhibitor or glucagon like peptide-1 analogue) may improve postprandial hypertriglyceridemia. …”
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36883por Tseng, Chin-Hsiao“…Older age, longer diabetes duration, male sex, and use of insulin, sulfonylurea, calcium channel blockers, aspirin, ticlopidine, clopidogrel and dipyridamole were significantly associated with a higher risk in sitagliptin users, but dyslipidemia and use of metformin and statin were protective. In conclusion, sitagliptin increases the risk of heart failure hospitalization within one year of its use, but reduces the risk thereafter. …”
Publicado 2016
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36884por Alswat, Khaled A., Al-shehri, Abdullah D., Aljuaid, Tariq A., Alzaidi, Bassam A., Alasmari, Hassan D.“…The mean overall GPA was 82.44% and the mean GPA for science subjects was 70.91%. No statically significant difference in the BMI was found between those who achieved >90% of the overall grade compared with those who achieved <90%. …”
Publicado 2017
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36885“…Since methotrexate doesn’t interfere with blood lipids, platelet aggregation or insulin resistance, the protective association may originate from mechanisms other than those exerted by antiplatelet drugs or statins.…”
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36886por Seliger, Corinna, Meier, Christoph R, Becker, Claudia, Jick, Susan S, Proescholdt, Martin, Bogdahn, Ulrich, Hau, Peter, Leitzmann, Michael F“…By comparison, high-density lipoprotein, triglycerides, fasting serum glucose, and use of ACE-inhibitors, AT-II inhibitors, beta-blockers, diuretics, calcium antagonists, nitrates, or statins were not associated with risk of meningioma. …”
Publicado 2016
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36887por Zagatina, Angela, Krylova, Ludmila, Vareldzhan, Yuliya, Tyurina, Tatyana V., Clitsenko, Olga, Zhuravskaya, Nadezhda“…All the patients with CAD were prescribed acetylsalicylic acid, statins, beta-blockers and ACE inhibitors. Eighty-seven percents of the patients took medication regularly. …”
Publicado 2013
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36888“…Stratification also discriminates higher from lower risk patients who may need intensive statin or aspirin prevention, while avoiding overtreatment in lower risk cases. …”
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36889por Legro, Richard S., Arslanian, Silva A., Ehrmann, David A., Hoeger, Kathleen M., Murad, M. Hassan, Pasquali, Renato, Welt, Corrine K.“…Thiazolidinediones have an unfavorable risk-benefit ratio overall, and statins require further study.…”
Publicado 2013
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36890por Liang, Wen-Chen, Uruha, Akinori, Suzuki, Shigeaki, Murakami, Nobuyuki, Takeshita, Eri, Chen, Wan-Zi, Jong, Yuh-Jyh, Endo, Yukari, Komaki, Hirofumi, Fujii, Tatsuya, Kawano, Yutaka, Mori-Yoshimura, Madoka, Oya, Yasushi, Xi, Jianying, Zhu, Wenhua, Zhao, Chongbo, Watanabe, Yurika, Ikemoto, Keisuke, Nishikawa, Atsuko, Hamanaka, Kohei, Mitsuhashi, Satomi, Suzuki, Norihiro, Nishino, Ichizo“…Antibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) have recently been associated with immune-mediated necrotizing myopathy, especially in patients with statin exposure. As the data are very limited concerning phenotypes and treatment in paediatric patients, we aimed to identify the paediatric patients positive for anti-HMGCR antibodies and clarify their features and therapeutic strategies. …”
Publicado 2017
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36891“…Thrombolytic therapy for stroke in CKD has shown an increased risk of symptomatic intracranial hemorrhage or serious systemic hemorrhage, and the therapeutic effects may be attenuated. Benefit of statin therapy in dialysis patient as preventive therapy has not been shown to be beneficial. …”
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36892“…Intensive medical treatment includes high intensity statins, diabetes and blood pressure control, and aggressive antiplatelet treatment. …”
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36893por Jensen, Majken Linnemann, Jørgensen, Marit Eika, Hansen, Ebba Holme, Aagaard, Lise, Carstensen, Bendix“…METHODS: Adherence to six medicine groups (metformin, sulfonylureas, acetylsalicylic acid, thiazide diuretics, renin angiotensin system inhibitors, and statins) were analysed among 5,232 patients with type 2 diabetes at a tertiary referral hospital during 1998–2009. …”
Publicado 2017
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36894por Snaterse, Marjolein, Jorstad, Harald T, Heiligenberg, Marlies, ter Riet, Gerben, Boekholdt, S Matthijs, Scholte op Reimer, Wilma, Peters, Ron J“…To enable comparison between the various types and dosages of statins, we used the average lipid-lowering potency (ALLP, % LDL-C lowering) as an indicator of lipid-lowering medication intensity. …”
Publicado 2017
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36895por Chui, Philip W., Parzynski, Craig S., Nallamothu, Brahmajee K., Masoudi, Frederick A., Krumholz, Harlan M., Curtis, Jeptha P.“…METHODS AND RESULTS: We linked the National Cardiovascular Data Registry (NCDR) CathPCI Registry with Medicare claims data to assess hospital performance on established PCI process measures (aspirin, thienopyridines, and statins on discharge; door‐to‐balloon time; and referral to cardiac rehabilitation), newly proposed PCI process measures (documentation of contrast dose, glomerular filtration rate, and PCI indication; appropriate indication for elective PCI; and use of embolic protection device), and a composite of all process measures. …”
Publicado 2017
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36896por Ko, Young-Guk, Ahn, Chul-Min, Min, Pil-Ki, Lee, Jae-Hwan, Yoon, Chang-Hwan, Yu, Cheol Woong, Lee, Seung Whan, Lee, Sang-Rok, Choi, Seung Hyuk, Koh, Yoon Seok, Chae, In-Ho, Choi, Donghoon“…At hospital discharge, only 73.1% of patients received dual antiplatelet therapy and 69.2% received a statin. CONCLUSION: The majority of Korean patients with PAD exhibited conventional risk factors, such as male sex, older age, diabetes, and hypertension with coexisting CAD. …”
Publicado 2017
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36897“…On multivariate logistic regression analysis, the risk factor that remained independently statically significant associated with developing pertussis was presence of infected person in the family AOR (adjusted odds ratio): 5.859, (95% CI 2.526–13.589). …”
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36898por Zomer, Ella, Osborn, David, Nazareth, Irwin, Blackburn, Ruth, Burton, Alexandra, Hardoon, Sarah, Holt, Richard Ian Gregory, King, Michael, Marston, Louise, Morris, Stephen, Omar, Rumana, Petersen, Irene, Walters, Kate, Hunter, Rachael Maree“…At baseline, each cardiovascular risk algorithm was applied and those considered high risk (> 10%) were assumed to be prescribed statin therapy while others received usual care. PRIMARY AND SECONDARY OUTCOME MEASURES: Quality-adjusted life years (QALYs) and costs were accrued for each algorithm including no algorithm, and cost-effectiveness was calculated using the net monetary benefit (NMB) approach. …”
Publicado 2017
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36899por Ziegler, Verena, Henninger, Christian, Simiantonakis, Ioannis, Buchholzer, Marcel, Ahmadian, Mohammad Reza, Budach, Wilfried, Fritz, Gerhard“…Therefore, we investigated whether pharmacological targeting of Rho signaling by the HMG-CoA-reductase inhibitor lovastatin influences ionizing radiation (IR)-induced toxicity in primary human lung fibroblasts, lung epithelial and lung microvascular endothelial cells in vitro and subchronic mouse lung tissue damage following hypo-fractionated irradiation (4x4 Gy). The statin improved the repair of radiation-induced DNA double-strand breaks (DSBs) in all cell types and, moreover, protected lung endothelial cells from IR-induced caspase-dependent apoptosis, likely involving p53-regulated mechanisms. …”
Publicado 2017
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36900“…The data were analyzed using appropriate statistical methods and a P < 0.05 was considered statically significant. RESULTS: A total of 559 (77.8%) women stopped levothyroxine after delivery, and the final follow-up data were available for 467 patients only. …”
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