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37501por Bond, Leila, Bowen, Gloria, Mertens, Benjamin, Denson, Keelie, Jordan, Kathleen, Vidakovic, Branislav, Mitchell, Cassie S.“…Random forests, which examined complex interactions, identified the following pharmaceuticals and supplements as most predictive to survival duration: Vitamin A, multivitamin, PEG supplements, alternative herbs, antihistamines, muscle relaxants, stimulant laxatives, and antispastics. Statins, metformin, and thiazide diuretics had insignificant associations with decreased survival.…”
Publicado 2020
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37502“…Independent variables recorded were gender, age, BMI, presence of diabetes or preoperative opioid or statin use, preoperative ROM, and use of ACEIs or ARBs. …”
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37503por Zhou, Yifang“…The normality of the noise distribution was tested at various spatial scales (2.1–9.8 mm) in the presence of ASIR (10–100%) with a wide range of doses (2.24–38 mGy). The statically defined minimum detectable contrast (MDC) was used as the image quality metric. …”
Publicado 2020
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37504por Xicoy, Helena, Brouwers, Jos F., Kalnytska, Oleksandra, Wieringa, Bé, Martens, Gerard J. M.“…Opposite to what has been previously described, the cholesterol-lowering drug statins did not have a protective effect, while low doses of cholesterol supplementation partially protected SH-SY5Y cells from 6-OHDA toxicity. …”
Publicado 2019
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37505por Schulte, Benjamin, Wübbolding, Maximilian, Marra, Fiona, Port, Kerstin, Manns, Michael P, Back, David, Cornberg, Markus, Stichtenoth, Dirk O, Höner zu Siederdissen, Christoph, Maasoumy, Benjamin“…Relevant DDIs most frequently occurred with proton pump inhibitors, metamizole, statins, and carvedilol. CONCLUSIONS: DDIs during antiviral treatment still affect about 40% of HCV patients. …”
Publicado 2020
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37506por Gögele, Clemens, Hahn, Judith, Elschner, Cindy, Breier, Annette, Schröpfer, Michaela, Prade, Ina, Meyer, Michael, Schulze-Tanzil, Gundula“…The experiments were performed using embroidered P(LA-CL)/PLA scaffolds that were seeded dynamically or statically with LACL-derived fibroblasts. Scaffold cytocompatibility, cell survival, numbers, metabolic activity, ultrastructure and sulfated glycosaminoglycan (sGAG) synthesis were evaluated. …”
Publicado 2020
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37507por Morieri, Mario Luca, Shah, Hetal S., Sjaarda, Jennifer, Lenzini, Petra A., Campbell, Hannah, Motsinger-Reif, Alison A., Gao, He, Lovato, Laura, Prudente, Sabrina, Pandolfi, Assunta, Pezzolesi, Marcus G., Sigal, Ronald J., Paré, Guillaume, Marcovina, Santica M., Rotroff, Daniel M., Patorno, Elisabetta, Mercuri, Luana, Trischitta, Vincenzo, Chew, Emily Y., Kraft, Peter, Buse, John B., Wagner, Michael J., Cresci, Sharon, Gerstein, Hertzel C., Ginsberg, Henry N., Mychaleckyj, Josyf C., Doria, Alessandro“…We investigated whether genetic variability in the PPARA gene, coding for the pharmacological target of fibrates (PPAR-α), could be used to improve the selection of patients with type 2 diabetes who may derive cardiovascular benefit from addition of this treatment to statins. We identified a common variant at the PPARA locus (rs6008845, C/T) displaying a study-wide significant influence on the effect of fenofibrate on major cardiovascular events (MACE) among 3,065 self-reported white subjects treated with simvastatin and randomized to fenofibrate or placebo in the ACCORD-Lipid trial. …”
Publicado 2020
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37508“…Pharmacist intervention caused significant (P-value < 0.05) improvement (increasing) in the prescribing of β-blockers, ACE inhibitors/ARBs, statins, and the proportion of patients who received all optimal five therapies (from 35% in observation phase to 80% after intervention). …”
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37509“…Other therapeutic agents that have been used include infliximab, cyclosporine, glucocorticoids, and statins. KD has been associated with several long-term sequelae.…”
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37510“…The risk for CVD among depressed dyslipidemia patients for high (aHR, 1.42; 95% CI, 1.06 to 1.90), medium (aHR, 1.17; 95% CI, 0.91 to 1.52), and low (aHR, 1.25; 95% CI, 1.05 to 1.50) statin compliance patients tended to be increased compared to patients without pre-existing dyslipidemia. …”
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37511por Dahlmann, Mathias, Werner, Rebecca, Kortüm, Benedikt, Kobelt, Dennis, Walther, Wolfgang, Stein, Ulrike“…Here we report, that treating high MACC1 expressing CRC cells with a combination of statins and standard therapeutics increased the rate of cytotoxicity and resulted in higher treatment response.…”
Publicado 2020
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37512“…Both descriptive and inferential statics were applied to analyze the data. RESULTS: A total of 594 adults participated in the study; 70.4% of them were female. …”
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37513por Feng, Lei, Nian, Shiyan, Tong, Zongwu, Zhu, Ying, Li, Ying, Zhang, Chunting, Bai, Xuejing, Luo, Xuan, Wu, Mengna, Yan, Zefeng“…CONCLUSIONS: The definition of dyslipidaemia, the atherosclerotic cardiovascular disease risk assessment and the initiation/goals of statin therapy should fully consider age-related trends in lipid levels and sex differences.…”
Publicado 2020
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37514“…In the 3-year follow-up period the proportion of days covered rates for ACE-inhibitors (60.95% vs. 58.92%), anti-platelet agents (74.20% vs. 70.66%), statins (54.18% vs. 52.13%), and β-blockers (61.95% vs. 52.64%) were higher in the DMP group. …”
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37515por Jennings, Catriona S, Kotseva, Kornelia, Bassett, Paul, Adamska, Agnieszka, Wood, David“…Prescribing was highest for antiplatelets (94%) and statins (85%). 81% were advised to attend cardiac rehabilitation (86% <60 years vs 79% ≥60 years; 82% men vs 77% women; 93% coronary artery bypass grafting vs 59% unstable angina), 85% attended if advised; 69% attended overall. …”
Publicado 2020
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37516por Sabbatinelli, Jacopo, Orlando, Patrick, Galeazzi, Roberta, Silvestri, Sonia, Cirilli, Ilenia, Marcheggiani, Fabio, Dludla, Phiwayinkosi V., Giuliani, Angelica, Bonfigli, Anna Rita, Mazzanti, Laura, Olivieri, Fabiola, Antonicelli, Roberto, Tiano, Luca“…Fifty-one subjects with low-density lipoprotein (LDL) cholesterol levels of 130–200 mg/dL, not taking statins or other lipid lowering treatments, moderate (2.5%–6.0%) endothelial dysfunction as measured by flow-mediated dilation (FMD) of the brachial artery, and no clinical signs of cardiovascular disease were randomized to receive either ubiquinol (200 or 100 mg/day) or placebo for 8 weeks. …”
Publicado 2020
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37517“…We defined the original risk factors previously identified in the risk score for major NSAID toxicity: age; male sex; history of cardiovascular disease, hypertension, and diabetes; tobacco use; statin use; elevated serum creatinine and hematocrit values; and RA. …”
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37518“…Other pharmacological agents are thought to increase ACE2 expression, including statins and proliferator-activated receptor gamma (PPAR-γ) agonists. …”
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37519por Hickernell, Thomas R., Kaidi, Austin C., Davignon, Robert, Geller, Jeffrey A., Cooper, H. John, Shah, Roshan P.“…. “+” indicates a cavity with a 2-mm smaller diameter that is 2-mm deeper. A 4750N statically applied force seated shells to a height that was comparable with shell height after an orthopaedic surgeon’s manual impaction. …”
Publicado 2020
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37520“…RESULTS: Two evaluation methods with three different registration patterns (at fully/half inhaled and fully exhaled positions) were used quantitatively at all internal target positions in phantom: The statical method evaluates the accuracy by stopping simulated breathing and dynamic with continued breathing patterns. …”
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