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37881por Szummer, Karolina, Wallentin, Lars, Lindhagen, Lars, Alfredsson, Joakim, Erlinge, David, Held, Claes, James, Stefan, Kellerth, Thomas, Lindahl, Bertil, Ravn-Fischer, Annica, Rydberg, Erik, Yndigegn, Troels, Jernberg, Tomas“…Evidence-based treatments increased: reperfusion from 66.2 to 81.7%; primary percutaneous coronary intervention: 4.5 to 78.0%; dual antiplatelet therapy from 0 to 89.6%; statin: 14.1 to 93.6%; beta-blocker: 78.2 to 91.0%, and angiotensin-converting-enzyme/angiotensin-2-receptor inhibitors: 40.8 to 85.2% (P-value for-trend <0.001 for all). …”
Publicado 2017
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37882por Ong, Kwok Leung, Waters, David D., Fayyad, Rana, Vogt, Liffert, Melamed, Shari, DeMicco, David A., Rye, Kerry‐Anne, Barter, Philip J.“…BACKGROUND: It is not known whether the concentration of high‐density lipoprotein (HDL) cholesterol is related to renal function in statin‐treated patients. We therefore investigated whether HDL cholesterol levels predicted renal function in atorvastatin‐treated patients in the TNT (Treating to New Targets) trial. …”
Publicado 2018
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37883por Pol, Tymon, Held, Claes, Westerbergh, Johan, Lindbäck, Johan, Alexander, John H., Alings, Marco, Erol, Cetin, Goto, Shinya, Halvorsen, Sigrun, Huber, Kurt, Hanna, Michael, Lopes, Renato D., Ruzyllo, Witold, Granger, Christopher B., Hijazi, Ziad“…Relationships between continuous levels of ApoA1 and ApoB and clinical outcomes were evaluated using Cox models adjusted for cardiovascular risk factors, medication including statins, and cardiovascular biomarkers. A composite ischemic outcome (ischemic stroke, systemic embolism, myocardial infarction, and cardiovascular death) was used as the primary end point. …”
Publicado 2018
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37884por Soran, Handrean, Banerjee, Moulinath, Mohamad, Jamal B., Adam, Safwaan, Ho, Jan Hoong, Ismaeel, Shakawan M., Dhage, Shaishav, Syed, Akheel A., Abdulla, Ibrahem M. A., Younis, Naveed, Malik, Rayaz A.“…Multiple logistic regression analysis showed that the presence of T2DM (P = 0.014), digoxin use (P = 0.01), statin use (P = 0.005), left-atrial size (P = 0.01), and LV ejection fraction (P = 0.008) were independent risk factors for immediate DCCV failure. …”
Publicado 2018
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37885por Hosomi, Naohisa, Nagai, Yoji, Kitagawa, Kazuo, Nakagawa, Yoko, Aoki, Shiro, Nezu, Tomohisa, Kagimura, Tatsuo, Maruyama, Hirofumi, Origasa, Hideki, Minematsu, Kazuo, Uchiyama, Shinichiro, Matsumoto, Masayasu“…However, the clinical efficacy for prevention of recurrent stroke was not conclusive with earlier statin treatment.…”
Publicado 2018
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37886por Han, Seungbong, Park, Gyung-Min, Kim, Yong-Giun, Park, Mahn-Won, Her, Sung Ho, Lee, Seung-Whan, Kim, Young-Hak“…At discharge, dual-anti platelet therapy, statin, beta-blockers, and angiotensin converting enzyme inhibitor or angiotensin receptor blocker were provided to 76,292 (94.1%), 71,411 (88.0%), 57,429 (70.8%), and 54,418 (67.1%) patients, respectively. …”
Publicado 2018
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37887por Marzel, Alex, Kouyos, Roger D, Reinschmidt, Sara, Balzer, Katharina, Garon, Fabienne, Spitaleri, Monica, Matthes, Nicolas, Suter, Paolo, Weber, Rainer, Staehelin, Cornelia, Lecompte, Thanh Doco, Tarr, Philip, Kovari, Helen“…Antiretroviral therapy (ART) can both directly modify total cholesterol and have drug-drug interactions with statins. This makes investigating modifiable behavioral predictors of total cholesterol a pertinent task. …”
Publicado 2018
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37888por Qin, Lang, Zhu, Xiaoming, Liu, Xiaoxia, Zeng, Meifang, Tao, Ran, Zhuang, Yan, Zhou, Yiting, Zhang, Zhaoyun, Yang, Yehong, Li, Yiming, Wang, Yongfei, Ye, Hongying“…In patients with or without taking statins, patients with LDL-c ≥3.37 mmol/L had higher SBP than patients with LDL-c <3.37 mmol/L. …”
Publicado 2018
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37889por Micó-Martínez, Pablo, García-Giménez, José-Luis, Seco-Cervera, Marta, López-Roldán, Andrés, Almiñana-Pastor, Pedro J., Alpiste-Illueca, Francisco, Pallardó, Federico V.“…Six different miRNAs were analyzed (miR-671, miR-122, miR-1306, miR-27a, miR-223, miR-1226), but only miR-1226 showed statically significant differences between the CP group and healthy controls (p<0.05). …”
Publicado 2018
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37890por Harewood-Marshall, Asanchia S., Craig, Leslie S., Martelly, Tanya P., Corbin, David O. C., Maul, Lauren, McIntosh-Clarke, Damani, Blackman, Tracey, George, Kenneth S., Hennis, Anselm J. M., Hambleton, Ian R., Rose, Angela M. C.“…Subsequent secondary prophylaxis, with a platelet aggregation inhibitor and a statin was advised. Barbados had no stroke unit or stroke team, and no official protocol for acute stroke management during the study period. …”
Publicado 2018
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37891por Song, Pil Sang, Ryu, Dong Ryeol, Kim, Min Jeong, Jeon, Ki-Hyun, Choi, Rak Kyeong, Park, Jin Sik, Song, Young Bin, Hahn, Joo-Yong, Gwon, Hyeon-Cheol, Ahn, Youngkeun, Jeong, Myung Ho, Choi, Seung-Hyuk“…We sought to develop a risk scoring specific for patients with AMI being treated with guideline-adherent optimal therapies, including percutaneous coronary intervention and all 5 medications (aspirin, thienopyridine, β-blocker, angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, and statin). METHODS: From registries, 12,174 AMI patients were evaluated. …”
Publicado 2018
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37892por Ozaki, Yuichi, Tanaka, Atsushi, Nishiguchi, Tsuyoshi, Komukai, Kenichi, Taruya, Akira, Satogami, Keisuke, Kashiwagi, Manabu, Kuroi, Akio, Matsuo, Yoshiki, Ino, Yasushi, Kitabata, Hironori, Kubo, Takashi, Hozumi, Takeshi, Akasaka, Takashi“…We registered one high-risk plaque per one patient by baseline OCT imaging, and then administrated high-intensity statin. Based on the follow-up OCT results, patients whose registered plaque was no longer high-risk plaque were classified into a responder group and the remains into a non-responder group. …”
Publicado 2018
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37893por Tang, Dave, Fakiola, Michaela, Syn, Genevieve, Anderson, Denise, Cordell, Heather J., Scaman, Elizabeth S. H., Davis, Elizabeth, Miles, Simon J., McLeay, Toby, Jamieson, Sarra E., Lassmann, Timo, Blackwell, Jenefer M.“…Top pathways/processes identified using Enrichr included: Reactome 2016 chylomicron-mediated lipid transport (P = 3.55 × 10(−7)); Wiki 2016 statin (P = 8.29 × 10(−8)); GO Biological Processes 2017 chylomicron remodelling (P = 1.92 × 10(−8)). …”
Publicado 2018
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37894por Gayam, Vijay, Mandal, Amrendra Kumar, Khalid, Mazin, Mukhtar, Osama, Gill, Arshpal, Garlapati, Pavani, Tiongson, Benjamin, Sherigar, Jagannath, Mansour, Mohammed, Mohanty, Smruti“…SVR 12 rates among patients with vitamin D deficiency, vitamin D insufficiency and normal vitamin D levels were 92%, 96.2%, and 97.2% respectively and was not statically significant (P = 0.214). A total of 71 patients were cirrhotic. …”
Publicado 2018
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37895por Jingu, Keiichi, Matsushita, Haruo, Yamamoto, Takaya, Umezawa, Rei, Ishikawa, Yojiro, Takahashi, Noriyoshi, Katagiri, Yu, Takeda, Kazuya, Kadoya, Noriyuki“…A meta-analysis was performed using Mantel-Haenszel statics with the fixed or random-effect model by Review Manager 5.3. …”
Publicado 2018
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37896“…Methods: We utilized a microsimulation model of statin and blood pressure treatment based on a TTT approach (Joint National Commission 7; Adult Treatment Panel III) or a BTT approach (treating those with 10-year CVD risk ≥10%, a modification and extension of recent American College of Cardiology/American Heart Association guidelines). …”
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37897por Martínez-Laguna, Daniel, Tebé, Cristian, Nogués, Xavier, Kassim Javaid, M, Cooper, Cyrus, Moreno, Victor, Diez-Perez, Adolfo, Collins, Gary S., Prieto-Alhambra, Daniel“…Both hip and major fracture prediction models included age, sex, previous major fracture, statins use, and calcium/vitamin D supplements; previous ischemic heart disease was also included for hip fracture and stroke for major fracture. …”
Publicado 2018
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37898“…Current treatments for cardiovascular and obesity-associated diseases, such as statin therapy, may be associated with several side effects. …”
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37899por Davidson, Sophia“…Anti-inflammatory drugs such as etanercept, statins or cyclooxygenase enzyme 2 inhibitors may temper IV induced inflammation, demonstrating the possibility of repurposing these drugs as single or adjunct therapies for IV infection. …”
Publicado 2018
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37900“…In addition, we do not recommend the use of statin in the absence of dyslipidemia as it causes PVAT deposition.…”
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