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39181por Boersma, Henderikus E., van Waateringe, Robert P., van der Klauw, Melanie M., Graaff, Reindert, Paterson, Andrew D., Smit, Andries J., Wolffenbuttel, Bruce H. R.“…In multivariable analysis for the combined endpoint, SAF retained its significance when sex, systolic blood pressure, HbA1c, total cholesterol, eGFR, as well as antihypertensive and statin medication were included. In a similar multivariable model, SAF was independently associated with mortality as a single outcome, but not with incident CVD. …”
Publicado 2021
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39182por Cortellini, Alessio, Di Maio, Massimo, Nigro, Olga, Leonetti, Alessandro, Cortinovis, Diego L, Aerts, Joachim GJV, Guaitoli, Giorgia, Barbieri, Fausto, Giusti, Raffaele, Ferrara, Miriam G, Bria, Emilio, D'Argento, Ettore, Grossi, Francesco, Rijavec, Erika, Guida, Annalisa, Berardi, Rossana, Torniai, Mariangela, Sforza, Vincenzo, Genova, Carlo, Mazzoni, Francesca, Garassino, Marina Chiara, De Toma, Alessandro, Signorelli, Diego, Gelibter, Alain, Siringo, Marco, Marchetti, Paolo, Macerelli, Marianna, Rastelli, Francesca, Chiari, Rita, Rocco, Danilo, Della Gravara, Luigi, Inno, Alessandro, Michele, De Tursi, Grassadonia, Antonino, Di Marino, Pietro, Mansueto, Giovanni, Zoratto, Federica, Filetti, Marco, Santini, Daniele, Citarella, Fabrizio, Russano, Marco, Cantini, Luca, Tuzi, Alessandro, Bordi, Paola, Minuti, Gabriele, Landi, Lorenza, Ricciardi, Serena, Migliorino, Maria R, Passiglia, Francesco, Bironzo, Paolo, Metro, Giulio, Adamo, Vincenzo, Russo, Alessandro, Spinelli, Gian Paolo, Banna, Giuseppe L, Friedlaender, Alex, Addeo, Alfredo, Cannita, Katia, Ficorella, Corrado, Porzio, Giampiero, Pinato, David J“…No association with clinical outcomes was found according to baseline statin, aspirin, β-blocker and metformin within the pembrolizumab cohort. …”
Publicado 2021
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39183por Wu, Bin, Zhou, Jianghua, Wang, Wenxin, Yang, Huilin, Xia, Meng, Zhang, Binghong, She, Zhigang, Li, Hongliang“…Patients who were aged < 18 or ≥ 85 years old, in pregnancy, with acute lethal organ injury (e.g., acute myocardial infarction, severe acute pancreatitis, acute stroke), hypothyroidism, malignant diseases, severe malnutrition, and those with normal lipid profile under lipid-lowering medicines (e.g., statin, niacin, fenofibrate, gemfibrozil, and ezetimibe) were excluded. …”
Publicado 2021
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39184por Gonzalez-Montesinos, Jose L., Fernandez-Santos, Jorge R., Vaz-Pardal, Carmen, Ponce-Gonzalez, Jesus G., Marin-Galindo, Alberto, Arnedillo, Aurelio“…However, there is only a statically significant difference between FBG and ONBG in EqCO(2). …”
Publicado 2021
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39185Metabolic Improvements After Gastric Sleeve Surgery in a Patient With Familial Partial Lipodystrophy“…Despite aggressive therapy with dietary changes, fenofibrate, statin, omega-3, and niacin, he had multiple episodes of pancreatitis with TG levels >5000 mg/dl on many occasions. …”
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39186“…In addition, mitotane is a strong CYP3A4 inducer which presents a challenge with statins, such as lovastatin, simvastatin, and atorvastatin. …”
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39187por Protic, Mladjan, Krsmanovic, Olivera, Solajic, Nenad, Kukic, Biljana, Nikolic, Ivan, Bogdanovic, Bogdan, Radovanovic, Zoran, Kresoja, Milana, Mannion, Ciaran, Man, Yan-Gao, Stojadinovic, Alexander“…There is not a statistically significant difference in the assessment of RM+ by surgeon and pathologists per RLS, but it was statically significant on a per patient basis. RM determined by surgeon has better prognostic impact on recurrence rate and 1- and 3-year DFS than standard histopathological assessment.…”
Publicado 2021
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39188“…For patients with BCLA, the adjusted Cox regression suggested incidences of all-cause deaths in mTPC1group were statically higher than those in sTPC group, whereas the incidences of all-cause and cancer-specific death in the mTPC1 and mTPC2 groups were statistically lower than those in the sTPC group. …”
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39189por Shi, Boqun, Liu, Xi, Dong, Qiuting, Yang, Yuxiu, Cai, Zhongxing, Wang, Haoyu, Yin, Dong, Wang, Hongjian, Dou, Kefei, Song, Weihua“…The main end point was medication adherence, which was defined as participant compliance in taking all 4 cardioprotective medications that would improve the patient’s outcome (therapies included antiplatelet therapy, β-blockers, statins, and angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers). …”
Publicado 2021
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39190por Bou Chebl, Ralphe, Geha, Mirabelle, Assaf, Mohamad, Kattouf, Nadim, Haidar, Saadeddine, Abdeldaem, Karim, Halawi, Nour, Khamis, Mohamed, Makki, Maha, Tamim, Hani, Abou Dagher, Gilbert“…Among septic shock patients there was no statically significant difference in the AUC value of the L/A ratio compared to lactate (0.53 95% CI 0.45–0.61 vs 0.50 95% CI 0.43–0.58 respectively with a p-value = .11). …”
Publicado 2021
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39191por Gaitán-Duarte, H.G., Álvarez-Moreno, C., Rincón-Rodríguez, C.J., Yomayusa-González, N., Cortés, J.A., Villar, J.C., Bravo-Ojeda, J.S., García-Peña, A., Adarme-Jaimes, W., Rodríguez-Romero, V.A., Villate-Soto, S.L., Buitrago, G., Chacón-Sarmiento, J., Macias-Quintero, M., Vaca, C.P., Gómez-Restrepo, C., Rodríguez-Malagón, N.“…More randomized controlled trials are needed to compare the effectiveness and cost of treatment with this combination versus other drugs that have been shown to reduce mortality from SARS-CoV-2 infection and its usefulness in patients with chronic statin use.…”
Publicado 2021
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39192por Wei, Yueying, Lopes, Bernardo T., Eliasy, Ashkan, Wu, Richard, Fathy, Arwa, Elsheikh, Ahmed, Abass, Ahmed“…Among keratoconic eyes, statical significance was noticed up to order 12 in both eyes (p < 0.0001 for right eyes, p = 0.0003 for left eyes). …”
Publicado 2021
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39193por Kurani, Shaheen Shiraz, Lampman, Michelle A., Funni, Shealeigh A., Giblon, Rachel E., Inselman, Jonathan W., Shah, Nilay D., Allen, Summer, Rushlow, David, McCoy, Rozalina G.“…MAIN OUTCOMES AND MEASURES: The primary outcome was the attainment of all 5 components of the D5 metric of optimal diabetes care: glycemic control (hemoglobin A(1c) <8.0%), blood pressure (BP) control (systolic BP <140 mm Hg and diastolic BP <90 mm Hg), lipid control (use of statin therapy according to recommended guidelines), aspirin use (for patients with ischemic vascular disease), and no tobacco use. …”
Publicado 2021
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39194por Ryu, Wi-Sun, Hong, Keun-Sik, Jeong, Sang-Wuk, Park, Jung E., Kim, Beom Joon, Kim, Joon-Tae, Lee, Kyung Bok, Park, Tai Hwan, Park, Sang-Soon, Park, Jong-Moo, Kang, Kyusik, Cho, Yong-Jin, Park, Hong-Kyun, Lee, Byung-Chul, Yu, Kyung-Ho, Oh, Mi Sun, Lee, Soo Joo, Kim, Jae Guk, Cha, Jae-Kwan, Kim, Dae-Hyun, Lee, Jun, Han, Moon-Ku, Park, Man Seok, Choi, Kang-Ho, Lee, Juneyoung, Saver, Jeffrey L., Lo, Eng H., Bae, Hee-Joon, Kim, Dong-Eog“…After adjusting for covariates including age, sex, previous stroke, prestroke mRS score, admission NIHSS score, hypertension, diabetes, hyperlipidemia, smoking, atrial fibrillation, prestroke antiplatelet use, prestroke statin use, revascularization, season of stroke onset, and time from onset to hospital arrival, night-onset stroke was more prone to END (adjusted incidence 14.4% versus 12.8%, p = 0.006) and had a lower likelihood of favorable outcome (adjusted odds ratio, 0.88 [95% CI, 0.79 to 0.98]; p = 0.03) compared with day-onset stroke. …”
Publicado 2022
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39195por Croyal, Mikaël, Wargny, Matthieu, Chemello, Kevin, Chevalier, Chloé, Blanchard, Valentin, Bigot-Corbel, Edith, Lambert, Gilles, Le May, Cédric, Hadjadj, Samy, Cariou, Bertrand“…After adjustment for age, sex, body mass index, FPG, HbA(1c), and statin use, the plasma levels of apoC-I, apoC-II, apoC-III, apoE, apoF, apoH, apoJ, and apoL1 were positively associated with a high risk for T2D. …”
Publicado 2022
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39196“…According to pain location and pathology (muscle, intervertebral disc, bone, statics, postoperative) the orthoses were classified to anatomical extent and the mechanical limitation (bandage, bodice, corset, orthosis with shoulder straps and erecting orthosis). …”
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39197“…Compared with T1MI, patients with T2MI were: more likely to have pre-existing chronic kidney disease (OR 1.87; 95% CI 1.53 to 2.28) and chronic heart failure (OR 2.35; 95% CI 1.82 to 3.03), less likely to present with typical cardiac symptoms of chest pain (OR 0.19; 95% CI 0.13 to 0.26) and more likely to present with dyspnoea (OR 2.64; 95% CI 1.86 to 3.74); more likely to demonstrate non-specific ST-T wave changes on ECG (OR 2.62; 95% CI 1.81 to 3.79) and less likely to show ST elevation (OR 0.22; 95% CI 0.17 to 0.28); less likely to undergo coronary angiography (OR 0.09; 95% CI 0.06 to 0.12) and percutaneous coronary intervention (OR 0.06; 95% CI 0.04 to 0.10) or receive cardioprotective medications, such as statins (OR 0.25; 95% CI 0.16 to 0.38) and beta-blockers (OR 0.45; 95% CI 0.33 to 0.63). …”
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39198por Dubrofsky, Lisa, Lee, Jason F., Hajimirzarahimshirazi, Parisa, Liu, Hongyan, Weisman, Alanna, Lawler, Patrick R., Farkouh, Michael E., Udell, Jacob A., Cherney, David Z.“…There was higher uptake in evidence-based medication use including statins (93.2% vs 81.1%, P = .01), SGLT-2i (35.1% vs 4.1%, P < .01), and GLP-1 receptor agonists (13.5% vs 4.1%, P = .02), while RAAS inhibitor use was already high at baseline (81.8% vs 78.4%, P = .56). …”
Publicado 2022
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39199por Gratton, Jasmine, Finan, Chris, Hingorani, Aroon D., Humphries, Steve E., Futema, Marta“…Methods: The United Kingdom Biobank cohort was used to analyse the LDL-C (adjusted for statin use) and 12-SNP score distributions in self-reported WB (n = 353,166), SA (n = 7,016), and BC (n = 7,082) participants. …”
Publicado 2022
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39200por Sun, Baoqing, Ma, Teng, Li, Yalin, Yang, Ni, Li, Bohai, Zhou, Xinfu, Guo, Shuai, Zhang, Shukun, Kwok, Lai-Yu, Sun, Zhihong, Zhang, Heping“…IMPORTANCE Despite recent advances in therapeutic strategies and drug treatments (e.g., statins) for coronary artery disease (CAD), CAD-related mortality and morbidity remain high. …”
Publicado 2022
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