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“…BACKGROUND: Statin intolerance is a barrier to effective lipid-lowering treatment. …”
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“…Persuasive data from many randomized controlled trials and large, long-term observational studies indicate a modestly increased risk for the emergence of new diabetes after statin initiation. Several meta-analyses of many statin trials as well as longitudinal population-based studies suggest that the risk factors for diabetes in statin-treated persons include underlying risk for diabetes at baseline (specifically features of metabolic syndrome), the intensity of statin therapy, certain genetic traits independent of diabetes risk, and adherence to lifestyle factors. …”
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“…The analysis included 3285 adults: 1217 statin nonusers (37%), 903 unvaccinated statin nonusers (27%), 847 vaccinated statin users (26%), and 318 unvaccinated statin users (10%). …”
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“…Statins are a cornerstone of the pharmacologic treatment and prevention of atherosclerotic cardiovascular disease. …”
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“…However, the dose of statins and the degree of LDL-C reduction achieved with statins are different between Asian and Western patients. …”
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“…We compared performance to the ideal Bayesian learner and several suboptimal models that varied in both computational and memory demands. Under static and dynamic conditions, we found that, in both tasks, observers used suboptimal learning rules. …”
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“…A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the hospital due to concern for statin myopathy. …”
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“…Objective: To review the potential role and specific impact of statin drugs in women with PCOS. The evidence for this use of statins in PCOS is limited and still under further investigation. …”
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“…Moreover, we discuss whether there is still a place for statins in the treatment of particular AS patient subgroups.…”
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“…There are two primary options for presbyopia correction: the dynamic approach uses the residual accommodative capacity of the eye, and the static approach attempts to enhance the depth of focus of the optical system. …”
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“…The fungus Aspergillus (A.) terreus has dominated the biological production of the “blockbuster” drugs known as statins. The statins are a class of drugs that inhibit HMG-CoA reductase and lead to lower cholesterol production. …”
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“…Statins are well-tolerated, mainstay drugs in cardiovascular risk management. …”
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“…Here, we reviewed the effects of plasma lipids and statins on cognitive function. DATA SOURCES: We searched the PubMed database for research articles published through November 2017 with key words including “plasma lipids,” “hyperlipidemia,” “hypercholesterolemia,” “statins,” and “cognition function.” …”
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“…Some drugs, including statins, are proposed to be among the causes of peripheral neuropathy. …”
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