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14021por Niederberger, Ellen“…Therefore, novel strategies for the development of safe and highly efficacious pain killers are urgently needed. To reach this goal, it is necessary to clarify the causes and signal transduction cascades underlying the onset and progression of the different types of chronic pain. …”
Publicado 2020
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14022por Xie, Lihua, Yang, Wenqiang, Liu, Hongmei, Liu, Tong, Xie, Yugu, Lin, Feng, Zhou, Guofa, Zhou, Xiaohong, Wu, Kun, Gu, Jinbao, Yan, Guiyun, Chen, Xiao-Guang“…The attractiveness of Mix-5 to Ae. albopictus in the laboratory was assessed using Mosq-ovitraps and Electric Mosquito Killers. In the field, the effectiveness of generic BG-Lure, Mix-5 and a control treatment was compared with a baited Biogents Sentinel trap (BGS-trap) using a Latin square design. …”
Publicado 2019
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14023“…RECENT FINDINGS: Dyslipidemia may facilitate the development of hypertension, whereas the collaboration of these two silent killers potentiates the risk of atherosclerosis. The common pathophysiological denominator for hypertension and dyslipidemia is endothelial cell dysfunction, which manifests as dysregulation of homeostasis, redox balance, vascular tone, inflammation, and thrombosis. …”
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14024por Radic, Marko“…Methods have been developed to convert a patient's cytotoxic T cells into efficient and specific killers of cancer cells in patients with leukemia. …”
Publicado 2012
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14025“…From an evolutionary point of view, however, it is difficult to understand why an important, mostly post-mitotic and highly vulnerable organ like the brain would host numerous potential killers. This review is aimed to critically reconsider the term microglia neurotoxicity and to discuss experimental problems around microglia biology, that often have led to the conclusion that microglia are neurotoxic cells.…”
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14026“…Tissue‐resident memory T (T(RM)) cells are abundant in the memory T cell pool and remain resident in peripheral tissues, such as the skin, where they act as alarm sensors or cytotoxic killers. T(RM) cells persist long after the pathogen is eliminated and can respond rapidly upon reinfection with the same antigen. …”
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14027“…BACKGROUND: Inherited bacteria that kill male offspring, male-killers, are known to be common in insects, but little is understood about the mechanisms used by male-killing bacteria to kill males. …”
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14028por Chapurlat, Roland D, Gensburger, Deborah, Jimenez-Andrade, Juan M, Ghilardi, Joseph R, Kelly, Marilyn, Mantyh, Patrick“…One of the most common complications of fibrous dysplasia of bone (FD) is bone pain. Usual pain killers are often of inadequate efficacy to control this bone pain. …”
Publicado 2012
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14029por Scuteri, Damiana, Garreffa, Maria Roberta, Esposito, Stefania, Bagetta, Giacinto, Naturale, Maria Diana, Corasaniti, Maria Tiziana“…To gather information on the utilization of pain killers in demented patients a preliminary survey has been conducted in collaboration with the Calabrian Pharmacovigilance Territorial Service of the health district of Catanzaro (Italy). …”
Publicado 2018
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14030Case Series of Neurotrauma Managed by General Surgeon at Ladakh — The Highest Plateau State of Indiapor Deskit, Padma“…Trauma including neurotrauma is one of the major killers in the world. The health infrastructure in developing countries has a huge disparity, with super specialist care confined to big cities only. …”
Publicado 2021
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14031por Guerra, Marja Michelin, Garcia, Eduardo, de Mendonça Pilan, Renata Ribeiro, Rapoport, Priscila Bogar, Campanholo, Caio Barbosa, Martinelli, Eli Onivaldo“…PATIENTS AND METHODS: the patients were randomized according to surgery time to receive 7 days of amoxicillin associated with pain killers, or analgesic alone. During the first week of postoperative, we assessed the level of pain, oral intake acceptance, nausea and vomits, fever and return to daily activities. …”
Publicado 2015
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14032por Ahmad Najib, Mohamad, Selvam, Kasturi, Khalid, Muhammad Fazli, Ozsoz, Mehmet, Aziah, Ismail“…Infectious diseases are the world’s greatest killers, accounting for millions of deaths worldwide annually, especially in low-income countries. …”
Publicado 2022
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14033“…Neutrophils were in the past regarded as short-lived, indiscriminate killers of invading microorganisms. However, this view has changed quite dramatically in recent years. …”
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14034“…Patients with chronic pain are constantly looking for ways to mitigate their pain. Pain killers are not a permanent solution. In addition to the medical and nonmedical costs of rare diseases for both patients and health care providers, there is a need for sustainable sources of information that are available to help with pain and improve their quality of life, with the goal of reducing physician visits and hospital admissions. …”
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14035por Lehrer, Jonah“…Jonah Lehrer arms us with the tools we need, drawing on cutting-edge research as well as the real-world experiences of a wide range of “deciders”—from airplane pilots and hedge fund investors to serial killers and poker players. Lehrer shows how people are taking advantage of the new science to make better television shows, win more football games, and improve military intelligence. …”
Publicado 2009
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14036por Ding, Alexander“…Tobacco-related mortality is one of the biggest killers in American medicine. Evidence suggests that if adolescents can be kept tobacco-free, most will never start using tobacco. …”
Publicado 2005
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14037por Dragos, Dorin, Gilca, Marilena, Gaman, Laura, Vlad, Adelina, Iosif, Liviu, Stoian, Irina, Lupescu, Olivera“…Currently used conventional medication (ranging from pain-killers to biological agents) is potent, but frequently associated with serious, even life-threatening side effects. …”
Publicado 2017
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14038“…Atherosclerotic plaque rupture is the primary mechanism responsible for myocardial infarction and stroke, the top two killers worldwide. Despite being potentially fatal, the ubiquitous prevalence of atherosclerosis amongst the middle aged and elderly renders individual events relatively rare. …”
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14039por Dueñas-González, Alfonso, Lizano, Marcela, Candelaria, Myrna, Cetina, Lucely, Arce, Claudia, Cervera, Eduardo“…Cervical cancer remains one of the greatest killers of women worldwide. It is difficult to foresee a dramatic increase in cure rate even with the most optimal combination of cytotoxic drugs, surgery, and radiation; therefore, testing of molecular targeted therapies against this malignancy is highly desirable. …”
Publicado 2005
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14040por Gielen, Joris, Gupta, Harmala, Rajvanshi, Ambika, Bhatnagar, Sushma, Mishra, Seema, Chaturvedi, Arvind K, den Branden, Stef Van, Broeckaert, Bert“…RESULTS: The interviewees did not consider administration of painkillers in large doses an ethical problem, provided the pain killers are properly titrated. Mild palliative sedation was considered acceptable. …”
Publicado 2011
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