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14041“…Climate-sensitive diseases are among the largest global killers, hence major brunt of global climate change in terms of adverse health impact will be mostly borne by poor and developing countries in Asia, given the levels of poverty, nutional levels and poor public health infrastructure.…”
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14042Postpartum sacral stress fracture associated with mechanical sacroiliac joint disease: A case reportpor Hmida, Badii, Boudokhane, Soumaya, Migaou, Houda, Kalai, Amine, Jellad, Anis, Salah, Zohra Ben“…INTERVENTIONS: Treatment consisted in pain killers and tailored to a nonweight-bearing period of 3 months. …”
Publicado 2018
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14043por Buonsenso, Danilo, Iodice, Francesco, Cinicola, Bianca, Raffaelli, Francesca, Sowa, Solia, Ricciardi, Walter“…Growing evidences are showing the potential indirect effects of the Coronavirus Disease 2019 (COVID-19) on the health systems of low-resource settings, where diseases such as Tuberculosis, Human Immunodeficiency Virus (HIV) and Malaria represent major killers. Therefore, we performed a retrospective study aimed to evaluate the impact of COVID-19 on Malaria programs in a peripheral region of Sierra Leone, previously involved by the Ebola outbreak in 2015, when malaria care have been impaired since local health systems were overwhelmed by Ebola cases. …”
Publicado 2021
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14044por Galmiche, Antoine, Saidak, Zuzana, Bettoni, Jérémie, Ouendo, Martial, Testelin, Sylvie“…Furthermore, the patients often present comorbidities and receive several medical prescriptions (hypnotics, pain killers, anti-emetics, hemostatics, inotropes, antibiotics). …”
Publicado 2022
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14045por Fiore, Vito, Beretta, Rosalba, De Vito, Andrea, Barac, Aleksandra, Maida, Ivana, Joeseph Kelvin, David David, Piu, Claudia, Lai, Vincenzo, Madeddu, Giordano, Rubino, Salvatore, Stevanovic, Goran, Korica, Stefan, Babudieri, Sergio“…Steroids, oxygen, antifungal treatment, and pain killers were administered when appropriate. Both patients were asymptomatic, with normal vital parameters and blood exams, and were discharged in a good condition. …”
Publicado 2022
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14046por Vats, Vanshika, Nagori, Aditya, Singh, Pradeep, Dutt, Raman, Bandhey, Harsh, Wason, Mahika, Lodha, Rakesh, Sethi, Tavpritesh“…Shock is one of the major killers in intensive care units, and early interventions can potentially reverse it. …”
Publicado 2022
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14047Kill or corrupt: Mechanisms of action and drug-resistance of nucleotide analogues against SARS-CoV-2“…Their distinct mechanisms of action best exemplify the concept of 'killers' and 'corruptors'. We review available data regarding their ability to be incorporated and excised, and discuss the specific structural features that dictate their overall potency, toxicity, and mutagenic potential. …”
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14048por Lainšček, Duško, Golob-Urbanc, Anja, Mikolič, Veronika, Pantović-Žalig, Jelica, Malenšek, Špela, Jerala, Roman“…CAR-T cells are highly potent serial killers that may cause serious side effects, so their activity needs to be carefully controlled. …”
Publicado 2023
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14049“…BACKGROUND: Cryptococcosis, a fatal fungal infection of the central nervous system, is one of the major killers of AIDS patients and other immunocompromised hosts. …”
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14050“…DISCUSSION: Compared with open interventions, the subjective social advantages (shorter hospital stay, earlier return to work, less need for pain killers, and others) of laparoscopic hernia treatment have been extensively studied. …”
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14051“…If the defense mechanism of body fails to combat them or they are not properly utilized in the body –these silent killers pose a threat by injuring tissues, their proteins and fat contents. …”
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14052por Friedman, Gregory K, Beierle, Elizabeth A, Gillespie, George Yancey, Markert, James M, Waters, Alicia M, Chen, Chun-Yu, Denton, Nicholas L, Haworth, Kellie B, Hutzen, Brian, Leddon, Jennifer L, Streby, Keri A, Wang, Pin-Yi, Cripe, Timothy P“…Viruses engineered to exploit this weakness, like mutant HSV, can be safely employed as tumor cell killers, since normal cells retain these antiviral strategies. …”
Publicado 2015
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14053Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgiapor Sandrini, Giorgio, De Icco, Roberto, Tassorelli, Cristina, Smania, Nicola, Tamburin, Stefano“…The limited efficacy of current pain-killers and prophylactic treatments stands among the main reasons for this phenomenon. …”
Publicado 2017
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14054por Dembla, Sandeep, Behrendt, Marc, Mohr, Florian, Goecke, Christian, Sondermann, Julia, Schneider, Franziska M, Schmidt, Marlene, Stab, Julia, Enzeroth, Raissa, Leitner, Michael G, Nuñez-Badinez, Paulina, Schwenk, Jochen, Nürnberg, Bernd, Cohen, Alejandro, Philipp, Stephan E, Greffrath, Wolfgang, Bünemann, Moritz, Oliver, Dominik, Zakharian, Eleonora, Schmidt, Manuela, Oberwinkler, Johannes“…Opioids, agonists of µ-opioid receptors (µORs), are the strongest pain killers clinically available. Their action includes a strong central component, which also causes important adverse effects. …”
Publicado 2017
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14055por Spahn, Viola, Del Vecchio, Giovanna, Rodriguez-Gaztelumendi, Antonio, Temp, Julia, Labuz, Dominika, Kloner, Michael, Reidelbach, Marco, Machelska, Halina, Weber, Marcus, Stein, Christoph“…Novel pain killers without adverse effects are urgently needed. …”
Publicado 2018
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14056por Iorgoveanu, Corina, Zaghloul, Ahmed, Desai, Aakash, Krishnan, Anand M, Balakumaran, Kathir“…Cardiovascular diseases, including heart disease and stroke, are the world’s largest killers. More than 800,000 people die from cardiovascular disease each year in the United States (US). …”
Publicado 2018
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14057por Ripani, Umberto, Manzarbeitia-Arroba, Paloma, Guijarro-Leo, Sandra, Urrutia-Graña, Javier, De Masi-De Luca, Alessandra“…A better quality of life was founded in Group B at 12 months in group B(p<0.05) and less use of pain killers/monthly(p<0.05). CONCLUSION: There is no denying that vitamin C benefits everybody, whether they have arthritis or not. …”
Publicado 2019
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14058por Kuznetsova, Tatyana A., Smolina, Tatyana P., Makarenkova, Ilona D., Ivanushko, Lydmila A., Persiyanova, Elena V., Ermakova, Svetlana P., Silchenko, Artem S., Zaporozhets, Tatyana S., Besednova, Natalya N., Fedyanina, Lydmila N., Kryzhanovsky, Sergey P.“…Using flow cytometry, we found that all examined fucoidans induce the maturation of dendritic cells, enhance the ability of neutrophils to migrate and adhere, activate monocytes and enhance their antigen-presenting functions, and increase the cytotoxic potential of natural killers. Fucoidans increase the production of hepatitis B virus (HBs) specific IgG and cytokine Th1 (IFN-γ, TNF-α) and Th2 (IL-4) profiles in vivo. …”
Publicado 2020
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14059por Muhialdin, Belal J., Zawawi, Norhasnida, Abdull Razis, Ahmad Faizal, Bakar, Jamilah, Zarei, Mohammad“…The mechanism of action was reported to be due to the stimulation of the immune system function via enhancing natural killers cell toxicity, enhance the production of pro-inflammatory cytokines, and increasing the cytotoxic of T lymphocytes (CD3(+), CD16(+), CD56(+)). …”
Publicado 2021
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14060“…Tuberculosis (TB) remains one of the leading infectious killers in the world, infecting approximately a quarter of the world’s population with the causative organism Mycobacterium tuberculosis (M. tb). …”
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