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  1. 14081
    “…One of the most frequent co-morbidities with SSc is interstitial lung disease (ILD), which is also one of the biggest killers among SSc patients. CASE PRESENTATION: The authors present a rare case of diffuse SSc with ILD and myocardial infarction having a history of Raynaud phenomenon, skin thickening, and shortness of breath. …”
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    Systemic sclerosis with interstitial lung disease and myocardial infarction: a case report
  2. 14082
    “…Respiratory ailments are major human killers, especially in developing countries. Tuberculosis (TB) is an infectious disease causing a threat to human healthcare. …”
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    In Vitro Antimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms
  3. 14083
    “…Oncolytic myxoma virus (MYXV) exhibits potent anti-cancer efficacy against human cancers like multiple myeloma (MM) and can arm transplant-derived T cells to become more effective cancer killers in vitro and in an immunodeficient xenotransplant murine model. …”
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    Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor
  4. 14084
    “…Chimeric antigen receptor T (CAR-T) cells are effective serial killers with a faster off-rate from dying tumor cells than CAR-T cells binding target cells through their T cell receptor (TCR). …”
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    Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity
  5. 14085
    por Benton, Michael J.
    Publicado 2018
    “…A key question is how massive eruptions during these events, and others, could have killed life in the sea and on land; proposed killers are reviewed here. In the oceans, benthos and plankton were killed by anoxia–euxinia and lethal heating, respectively, and the habitable depth zone was massively reduced. …”
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    Hyperthermal-driven mass extinctions: killing models during the Permian–Triassic mass extinction
  6. 14086
    “…Carbon screen-printed electrode (SPCE), multi-walled carbon nanotubes modified screen-printed electrode (SPCNTE), carbon nanofibers modified screen-printed electrode (SPCNFE), and graphene modified screen-printed electrode (SPGPHE) were in a pioneer way tested as sensors for the simultaneous determination of the two most consumed pain-killers, paracetamol (PA) and ibuprofen (IB), and the stimulant caffeine (CF) in water by differential pulse voltammetry (DPV). …”
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    Commercial Screen-Printed Electrodes Based on Carbon Nanomaterials for a Fast and Cost-Effective Voltammetric Determination of Paracetamol, Ibuprofen and Caffeine in Water Samples
  7. 14087
    “…Both groups showed a noticeable high use of pain killers (all workers 79%). The higher frequency of symptoms in the e-waste group can be explained by the specific recycling tasks, such as burning or dismantling. …”
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    Health Consequences for E-Waste Workers and Bystanders—A Comparative Cross-Sectional Study
  8. 14088
    “…On several previous orthopedic surgery clinic visits, pathological back pain had not been considered and pain killers had been prescribed because he had low back pain due to lumbar spinal canal stenosis. …”
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    Tachyarrhythmia improved by management of low back pain in a patient with delayed diagnosis of infective spondylodiscitis: A case report
  9. 14089
    “…Innovative AM applications can play an essential role to combat invisible killers (COVID-19) and its hydra-headed pandemic effects on humans, economics and society.…”
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    Review on 3D printing: Fight against COVID-19
  10. 14090
    “…Two models, (1) the WHO and the Johns Hopkins Bloomberg School of Public Health’s Maternal and Child Epidemiology Estimation (MCEE) group’s Child Mortality Estimation (WHO-MCEE) and (2) the Institute for Health Metrics and Evaluation (IHME) Global Burden of Disease Study (GBD 2017), identified meningitis, encephalitis and neonatal sepsis, collectively, to be the second and third largest infectious killers of children under five years, respectively. …”
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    The Global Burden of Meningitis in Children: Challenges with Interpreting Global Health Estimates
  11. 14091
    “…Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates. …”
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    Consensus on the application of negative pressure wound therapy of diabetic foot wounds
  12. 14092
    por Giussani, Dino A.
    Publicado 2021
    “…Heart disease remains one of the greatest killers. In addition to genetics and traditional lifestyle risk factors, we now understand that adverse conditions during pregnancy can also increase susceptibility to cardiovascular disease in the offspring. …”
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    Breath of Life: Heart Disease Link to Developmental Hypoxia
  13. 14093
    por Bartfai, Tamas, Lees, Graham V
    Publicado 2013
    “…Since many current pain killers are abused, there are other hurdles. Despite the many difficulties, society needs new pain killers at the same time that notable pharma are pulling out, despite the economic opportunity. …”
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    Therapeutic areas: Strategically important diseases of the future
  14. 14094
    “…Non-small cell lung cancer (NSCLC) is one of the leading cancer killers. Apigenin (Api) and Naringenin (Nar) are natural bioactive substances obtained in various vegetables and fruits, possessing anti-tumor effects across multiple studies. …”
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    Synergism Antiproliferative Effects of Apigenin and Naringenin in NSCLC Cells
  15. 14095
    por Campbell, Tim, Campbell, Alana
    Publicado 2007
    “…Communicable diseases, particularly HIV/AIDs, will continue to be the most important killers among the poor. However, new risks will emerge for several reasons. …”
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    Emerging Disease Burdens and the Poor in Cities of the Developing World
  16. 14096
    “…In CD-1 mice, peak lymphocyte numbers occurred in blood on postnatal day 10 (dl0) including those for natural killers (NK1.1), B cells (CD19), T helper (CD3CD4), naïve T helper (CD4CD62L(pos)CD44(low)), memory T helper (CD4CD62L(neg)CD44(high)), and T cytotoxic (CD3CD8) cells. …”
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    Maturation of Lymphocyte Immunophenotypes and Memory T Helper Cell Differentiation During Development in Mice
  17. 14097
    por Bru, Antonio, Cardona, Pere-Joan
    Publicado 2010
    “…METHODOLOGY: We present here a new 2D cellular automata model based on the concept of a multifunctional process that includes key factors such as the chemokine attraction of the cells; the role of innate immunity triggered by natural killers; the presence of neutrophils; apoptosis and necrosis of infected macrophages; the removal of dead cells by macrophages, which induces the production of foamy macrophages (FMs); the life cycle of the bacilli as a determinant for the evolution of infected macrophages; and the immune response. …”
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    Mathematical Modeling of Tuberculosis Bacillary Counts and Cellular Populations in the Organs of Infected Mice
  18. 14098
    por Mooren, L, Grzebieta, R
    Publicado 2009
    “…Currently, road trauma is one of the biggest killers and causes of serious and disabling injuries in the world. …”
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    Road manslaughter—or just the cost of progress?
  19. 14099
    por Chhajer, Rudra, Ali, Nahid
    Publicado 2014
    “…Among the many protozoan diseases, the leishmaniases have emerged as one of the largest parasite killers of the world, second only to malaria. There are three types of leishmaniasis namely cutaneous (CL), mucocutaneous (ML), and visceral (VL), caused by a group of more than 20 species of Leishmania parasites. …”
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    Genetically Modified Organisms and Visceral Leishmaniasis
  20. 14100
    “…Interleukin 18 (IL-18) is one of the pro-inflammatory cytokines expressed by macrophages, suggesting that it plays important physiological and immunological functions, among the others: stimulation of natural killers (NKs) and T cells to interferon gamma (IFN- [Formula: see text]) synthesis. …”
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    Theoretical Studies on the Engagement of Interleukin 18 in the Immuno-Inflammatory Processes Underlying Atherosclerosis
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