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421por Ito, Tomoki, Konishi, Akiko, Tsubokura, Yukie, Azuma, Yoshiko, Hotta, Masaaki, Yoshimura, Hideaki, Nakanishi, Takahisa, Fujita, Shinya, Nakaya, Aya, Satake, Atsushi, Ishii, Kazuyoshi, Nomura, Shosaku“…Lenalidomide is an immunomodulating derivative of thalidomide, which shows anti-tumor activity against myeloma cells with immunomodulation including augmentation of T-cell and natural killer cell function. Continuous treatment with this agent shows better survival benefit in patients with multiple myeloma and combined lenalidomide with dexamethasone (LEN-DEX) is a standard treatment regimen. …”
Publicado 2018
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422por Andualem, Zewudu, Adane, Tsegaye, Tigabu, Abiye, Yallew, Walelign Worku, Wami, Sintayehu Daba, Dagne, Henok, Azanaw, Jember, Guyasa, Gebisa, Azene, Zelalem Nigussie, Endalew, Mastewal“…In Ethiopia, pneumonia continues to be the major childhood problem and killer, particularly in the study area. However, evidence dealing with the problem is still unavailable. …”
Publicado 2020
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423“…Background: The clinical characteristics of coronavirus disease 2019 (COVID-19) have been well-studied, while effective predictors for clinical outcome and research on underlying mechanisms are scarce. …”
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424“…Liver hepatocellular carcinoma (LIHC) patients receiving cytokine-induced killer cell (CIK) immunotherapy at Sun Yat-sen University cancer center were enrolled for survival analysis. …”
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425por Bhattacharya, Niranjan“…BACKGROUND: Malaria is an annual killer of over one million people globally and its essential co-morbidity is anaemia. …”
Publicado 2006
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426por Hazeldine, Jon, Naumann, David N., Toman, Emma, Davies, David, Bishop, Jonathan R. B., Su, Zhangjie, Hampson, Peter, Dinsdale, Robert J., Crombie, Nicholas, Duggal, Niharika Arora, Harrison, Paul, Belli, Antonio, Lord, Janet M.“…BACKGROUND: Almost all studies that have investigated the immune response to trauma have analysed blood samples acquired post-hospital admission. …”
Publicado 2017
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427por Notz, Quirin, Schmalzing, Marc, Wedekink, Florian, Schlesinger, Tobias, Gernert, Michael, Herrmann, Johannes, Sorger, Lena, Weismann, Dirk, Schmid, Benedikt, Sitter, Magdalena, Schlegel, Nicolas, Kranke, Peter, Wischhusen, Jörg, Meybohm, Patrick, Lotz, Christopher“…OBJECTIVES: The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by the immune response. First studies indicate altered lymphocyte counts and function. …”
Publicado 2020
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428por Park, So-Jung, Kang, Hwi-Joong, Jun, Hyung-Joon, Shin, Seong-Hoon, Yoo, Hwa-Seung“…BACKGROUND: In recent studies, afatinib, a second-generation inhibitor, showed superior outcomes, when compared to the first-generation of EGFR-tyrosine kinase inhibitors (TKIs), such as erlotinib and gefitinib, in patients with advanced non-small cell lung cancer (NSCLC) harboring mutations of epidermal growth factor receptor (EGFR). …”
Publicado 2020
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429por Bachy, Emmanuel, Savage, Kerry J., Huang, Huiqiang, Kwong, Yok-Lam, Gritti, Giuseppe, Zhang, Qingyuan, Liberati, Anna Marina, Cao, Junning, Yang, Haiyan, Hao, Siguo, Hu, Jianda, Zhou, Keshu, Petrini, Mario, Russo, Filomena, Zhang, Huilai, Sang, Wei, Ji, Jie, Ferreri, Andrés José María, Damaj, Gandhi Laurent, Liu, Hui, Zhang, Wei, Ke, Xiaoyan, Ghiggi, Chiara, Huang, Sha, Li, Xiaotong, Yao, Hui, Paik, Jason, Novotny, William, Zhou, Wenxiao, Zhu, Hongjie, Zinzani, Pier Luigi“…Patients with relapsed/refractory (R/R) mature T- and natural killer (NK)–cell neoplasms lack effective treatments after failure of standard therapies. …”
Publicado 2023
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430por Lim, Shir Lynn, Woo, Kai Lee, Lim, Eleanor, Ng, Faclin, Chan, Mark Y., Gandhi, MihirEnlace del recurso
Publicado 2020
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431por Joerger, Markus, Calvo, Emiliano, Laubli, Heinz, Lopez, Juanita, Alonso, Guzmán, Corral de la Fuente, Elena, Hess, Dagmar, König, David, Sanchez Perez, Vicky, Bucher, Christoph, Jethwa, Sangeeta, Garralda, Elena“…The dose escalation part of the study explored doses 3, 6 and 12 µg/kg as single patient cohorts followed by 24–364 µg/kg in a 3+3 design. …”
Publicado 2023
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432por Pan, Ning, Jiang, Wei, Sun, Hang, Miao, Fengqin, Qiu, Jie, Jin, Hui, Xu, Jinhuan, Shi, Qian, Xie, Wei, Zhang, Jianqiong“…BACKGROUND: Natural killer (NK) cells activation has been reported to contribute to inflammation and liver injury during hepatitis B virus (HBV) infection both in transgenic mice and in patients. …”
Publicado 2011
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433por Zhang, Hailin, Li, Ao, Jiang, Youli, Chen, Wenqiu, Wang, Jin, Zhang, Peize, Deng, Guofang, Wang, Weiyu, Chen, Jingfang, Lin, YiEnlace del recurso
Publicado 2022
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434por Costabile, Adele, Bergillos-Meca, Triana, Rasinkangas, Pia, Korpela, Katri, de Vos, Willem M., Gibson, Glenn R.“…To date, many in vitro and in vivo studies focused on the application of synbiotics (prebiotics combined with probiotics) as a promising dietary approach to affect gut microbiota composition and improved functioning of the immune system. …”
Publicado 2017
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435por Haitov Ben Zikri, Zoya, Volis, Maryna, Mazur, Andrei, Orlova, Tatjana, Alon, Hana, Bar Yehuda, Sara, Gofman, Vladislav“…The aim of the current study was to compare the efficacy of combinations of various peripheral blocks on pain intensity and the use of pain killers, shortly after LC. …”
Publicado 2023
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436“…METHODS: A mixed-methods design was used. The study was conducted at Ocean Road Cancer Institute (ORCI) in Dar es Salaam, Tanzania. …”
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437por Gimeno-Feliu, Luis Andres, Calderón-Larrañaga, Amaia, Prados-Torres, Alexandra, Revilla-López, Concha, Diaz, Esperanza“…BACKGROUND: Although equity in health care is theoretically a cornerstone in Western societies, several studies show that services do not always provide equitable care for immigrants. …”
Publicado 2016
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438por Mocho, Inês, Rosário, Ana Filipa, Santos, Luís, Guerreiro, Eduardo, Delgado, Ana, Mendes, José João“…This study follows the principles of the Declaration of Helsinki. …”
Publicado 2021
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439por Malafoglia, Valentina, Ilari, Sara, Gioia, Chiara, Vitiello, Laura, Tenti, Michael, Iannuccelli, Cristina, Cristiani, Costanza Maria, Garofalo, Cinzia, Passacatini, Lucia Carmela, Viglietto, Giuseppe, Scavalli, Antonio Sili, Tomino, Carlo, Mollace, Vincenzo, Raffaeli, William, Di Franco, Manuela, Muscoli, CarolinaEnlace del recurso
Publicado 2023
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440“…Therefore, it may be expected that environmental contaminants adversely affect immune function of free-ranging seals inhabiting contaminated regions at least as seriously as observed in these studies.…”
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