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121por Wei, Liqiang, Yang, Lei, Ye, Jin, Cong, Jia, Li, Xin, Yao, Na, Yang, Jing, Cui, Xueying, Ding, Jing, Wu, Yiping, Wang, Jingwen“…The primary endpoint was the overall response rate after 3 cycles of chemotherapy, and secondary study endpoints were complete response (CR), progression-free survival (PFS), and overall survival (OS). …”
Publicado 2020
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122“…Dendritic cells (DCs) and cytokine-induced killer (CIK) cells play an important role in the anti-tumor immune response. …”
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123por Zeng, Ruifang, Zhu, Wenzhuo, Jiang, Li, Zhu, Xi, Gao, Yan, Xia, Yi, Bai, Bing, Shikama, Naoto, Janetos, Timothy M., Dalia, Samir, Alpdogan, Onder, Wang, Xiaoxiao, Zhu, Lingling, Li, Pengfei“…CONCLUSIONS: In this large cohort study, we found that the ACD4C was associated with survival outcomes in ENKTL patients. …”
Publicado 2022
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124por Killer, Jiří, Mekadim, Chahrazed, Pechar, Radko, Bunešová, Věra, Mrázek, Jakub, Vlková, EvaEnlace del recurso
Publicado 2018
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125por Huang, Huiqiang, Tao, Rong, Hao, Siguo, Yang, Yu, Cen, Hong, Zhou, Hui, Guo, Ye, Zou, Liqun, Cao, Junning, Huang, Yunhong, Jin, Jie, Zhang, Liling, Yang, Haiyan, Xing, Xiaojing, Zhang, Huilai, Liu, Yanyan, Ding, Kaiyang, Qi, Qinzhou, Zhu, Xiaoli, Zhu, Dan, Wang, Siyuan, Fang, Teng, Dai, Hangjun, Shi, Qingmei, Yang, Jason“…Relapsed or refractory extranodal natural killer/T-cell lymphoma (R/R ENKTL) is a rare and aggressive type of non-Hodgkin lymphoma with limited treatment options. …”
Publicado 2023
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126
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127por Schulte-Wrede, Ursula, Sörensen, Till, Grün, Joachim R., Häupl, Thomas, Hirseland, Heike, Steinbrich-Zöllner, Marta, Wu, Peihua, Radbruch, Andreas, Poddubnyy, Denis, Sieper, Joachim, Syrbe, Uta, Grützkau, Andreas“…Thus, the aim of this explorative study was to identify cell-based biomarkers in peripheral blood that could be used for a pre-treatment stratification of AS patients. …”
Publicado 2018
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128por Samarani, Suzanne, Mack, David R., Bernstein, Charles N., Iannello, Alexandre, Debbeche, Olfa, Jantchou, Prevost, Faure, Christophe, Deslandres, Colette, Amre, Devendra K., Ahmad, Ali“…BACKGROUND: Killer-cell Immunoglobulin-like Receptor (KIR) genes encode receptors, which are mainly expressed on, and control functional activities of, Natural Killer (NK) cells. …”
Publicado 2019
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129“…The present study aimed to develop a widely accepted prognostic nomogram for stage IE and IIE extranodal natural killer/T-cell lymphoma (ENKTCL) of the upper aerodigestive tract by using the Surveillance, Epidemiology, and End Results program database. …”
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130por Zhang, Yao, Liu, Yizhen, Xia, Zuguang, Jin, Jia, Xue, Kai, Wang, Jiachen, Sun, Hui, Lv, Fangfang, Liu, Xiaojian, Cao, Junning, Hong, Xiaonan, Guo, Ye, Ma, Xuejun, Zhang, Qunling“…BACKGROUND: To explore a more effective treatment strategy for newly diagnosed stage I and II extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, we conducted a prospective phase II study of sequential chemoradiotherapy with the L-asparaginase, dexamethasone, ifosfamide, cisplatin, and etoposide (DICE-L) regimen. …”
Publicado 2021
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131“…Although PMBL is an immunostimulant, it remains unknown whether treatment with PMBL influences natural killer cell activity (NKA). Hence, this case-control study compared the changes in IFN-γ levels (surrogate index for NKA) following PMBL treatment or time passing between the PMBL-treated group and controls. …”
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132por Bae, Woo Kyun, Lee, Byung Chan, Kim, Hyeon-Jong, Lee, Je-Jung, Chung, Ik-Joo, Cho, Sung Bum, Koh, Yang Seok“…BACKGROUND: To explore the feasibility and safety of natural killer (NK) cell therapy in HCC, we performed a prospective, open-label, phase I trial to evaluate the synergistic effect of locoregional high-dose autologous NK cell therapy in combination with hepatic arterial infusion chemotherapy (HAIC). …”
Publicado 2022
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133por Tercero, Almudena, Finlay, Dan, Asghedom, Liya H, Romasanta, Gladys R, Rice, Natalie T, Ranjbaran, Fatima, Stoltzman, Carrie, Cook, Jody, Blake, Joe, Delaney, Colleen, Hill, Joshua A“…Patients with COVID-19 who develop lymphopenia, particularly low numbers of circulating natural killer (NK) cells, are at high risk for disease progression. …”
Publicado 2022
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134
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135por Vey, Norbert, Karlin, Lionel, Sadot-Lebouvier, Sophie, Broussais, Florence, Berton-Rigaud, Dominique, Rey, Jérôme, Charbonnier, Aude, Marie, Delphine, André, Pascale, Paturel, Carine, Zerbib, Robert, Bennouna, Jaafar, Salles, Gilles, Gonçalves, Anthony“…PURPOSE: Anti-KIR monoclonal antibodies (mAbs) can enhance the antitumor responses of natural killer (NK) cells. We evaluated the safety of the anti-KIR2D mAb lirilumab in patients with various cancers. …”
Publicado 2018
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136por Kim, Jong Man, Cho, Sung Yoo, Rhu, Jinsoo, Jung, Miyoung, Her, Jung Hyun, Lim, Okjae, Choi, Gyu-Seong, Shin, Eui-Cheol, Hwang, Yu-Kyeong, Joh, Jae-Won“…We evaluated the safety and efficacy of ex vivo-expanded allogenic natural killer (NK) cells in those patients with modified International Union Against Cancer (UICC) stage T3. …”
Publicado 2021
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137por Fu, Hai-Yan, Bao, Wei-Min, Yang, Cai-Xia, Lai, Wei-Ju, Xu, Jia-Min, Yu, Hai-Yan, Yang, Yi-Na, Tan, Xu, Gupta, Ajay Kumar, Tang, Ying-Mei“…BACKGROUND: Kupffer cells and natural killer (NK) cells has been identified as contributing factors in the pathogenesis of hepatitis, but the detailed mechanism of these cell types in the pathogenesis of primary biliary cholangitis (PBC) is poorly understood. …”
Publicado 2020
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138“…BACKGROUND/OBJECTIVES: The present study investigated the hypothesis that a highly pure linear β-1,3-glucan produced by Agrobacterium sp. …”
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139por Xu, Peng-Peng, Xiong, Jie, Cheng, Shu, Zhao, Xia, Wang, Chao-Fu, Cai, Gang, Zhong, Hui-Juan, Huang, Heng-Ye, Chen, Jia-Yi, Zhao, Wei-Li“…BACKGROUND: A phase II study of methotrexate, etoposide, dexamethasone, and pegaspargase (MESA) sandwiched with radiotherapy for newly diagnosed, stage IE-IIE extranodal natural-killer/T-cell lymphoma, nasal-type (ENKTL) was conducted to explore its clinical efficacy and safety, as well as novel serum biomarkers upon anti-metabolic treatment. …”
Publicado 2017
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140por Han, Ying, Mu, Di, Liu, Ting, Zhang, Huan, Zhang, Jiali, Li, Shuzhan, Wang, Rui, Du, Weijiao, Hui, Zhenzhen, Zhang, Xinwei, Ren, Xiubao“…However, the objective response rate with these agents remains low, and the vast majority of NSCLC patients require alternative combination treatment regimens to prolong their survival. The purpose of this study was to evaluate the clinical efficacy of autologous cytokine‐induced killer (CIK) cell infusions combined with PD‐1 blocking antibodies in patients with NSCLC. …”
Publicado 2020
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