Reciprocal inhibition of PIN1 and APC/C(CDH1) controls timely G1/S transition and creates therapeutic vulnerability

por Ke, Shizhong, Dang, Fabin, Wang, Lin, Chen, Jia-Yun, Naik, Mandar T., Thavamani, Abhishek, Liu, Yansheng, Li, Wenxue, Kim, Nami, Naik, Nandita M., Sui, Huaxiu, Tang, Wei, Qiu, Chenxi, Koikawa, Kazuhiro, Batalini, Felipe, Wang, Xiaodong, Clohessy, John G., Heng, Yujing Jan, Lahav, Galit, Gray, Nathanael S., Zho, Xiao Zhen, Wei, Wenyi, Wulf, Gerburg M., Lu, Kun Ping
Publicado 2023

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities

por Casey, Alison E., Sinha, Ankit, Singhania, Rajat, Livingstone, Julie, Waterhouse, Paul, Tharmapalan, Pirashaanthy, Cruickshank, Jennifer, Shehata, Mona, Drysdale, Erik, Fang, Hui, Kim, Hyeyeon, Isserlin, Ruth, Bailey, Swneke, Medina, Tiago, Deblois, Genevieve, Shiah, Yu-Jia, Barsyte-Lovejoy, Dalia, Hofer, Stefan, Bader, Gary, Lupien, Mathieu, Arrowsmith, Cheryl, Knapp, Stefan, De Carvalho, Daniel, Berman, Hal, Boutros, Paul C., Kislinger, Thomas, Khokha, Rama
Publicado 2018

Phase I Clinical Trial of an Autologous Dendritic Cell Vaccine Against HER2 Shows Safety and Preliminary Clinical Efficacy

por Maeng, Hoyoung M., Moore, Brittni N., Bagheri, Hadi, Steinberg, Seth M., Inglefield, Jon, Dunham, Kim, Wei, Wei-Zen, Morris, John C., Terabe, Masaki, England, Lee C., Roberson, Brenda, Rosing, Douglas, Sachdev, Vandana, Pack, Svetlana D., Miettinen, Markku M., Barr, Frederic G., Weiner, Louis M., Panch, Sandhya, Stroncek, David F., Wood, Lauren V., Berzofsky, Jay A.
Publicado 2021

Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)

por Schoeberl, Birgit, Kudla, Art, Masson, Kristina, Kalra, Ashish, Curley, Michael, Finn, Gregory, Pace, Emily, Harms, Brian, Kim, Jaeyeon, Kearns, Jeff, Fulgham, Aaron, Burenkova, Olga, Grantcharova, Viara, Yarar, Defne, Paragas, Violette, Fitzgerald, Jonathan, Wainszelbaum, Marisa, West, Kip, Mathews, Sara, Nering, Rachel, Adiwijaya, Bambang, Garcia, Gabriela, Kubasek, Bill, Moyo, Victor, Czibere, Akos, Nielsen, Ulrik B, MacBeath, Gavin
Publicado 2017

Oncogenic mTOR signaling recruits myeloid-derived suppressor cells to promote tumor initiation

por Welte, Thomas, Kim, Ik Sun, Tian, Lin, Gao, Xia, Wang, Hai, Li, June, Holdman, Xue B., Herschkowitz, Jason I., Pond, Adam, Xie, Guorui, Kurley, Sarah, Nguyen, Tuan, Liao, Lan, Dobrolecki, Lacey E., Mo, Qianxing, Edwards, Dean P., Huang, Shixia, Xin, Li, Xu, Jianming, Li, Yi, Lewis, Michael T., Wang, Tian, Westbrook, Thomas F., Rosen, Jeffrey M., Zhang, Xiang H.-F.
Publicado 2016

DAXX drives de novo lipogenesis and contributes to tumorigenesis

por Mahmud, Iqbal, Tian, Guimei, Wang, Jia, Hutchinson, Tarun E., Kim, Brandon J., Awasthee, Nikee, Hale, Seth, Meng, Chengcheng, Moore, Allison, Zhao, Liming, Lewis, Jessica E., Waddell, Aaron, Wu, Shangtao, Steger, Julia M., Lydon, McKenzie L., Chait, Aaron, Zhao, Lisa Y., Ding, Haocheng, Li, Jian-Liang, Purayil, Hamsa Thayele, Huo, Zhiguang, Daaka, Yehia, Garrett, Timothy J., Liao, Daiqing
Publicado 2023

A three gene immunohistochemical panel serves as an adjunct to clinical staging of patients with head and neck cancer

por Ong, Chin-Ann J., Shannon, Nicholas B., Mueller, Stefan, Lek, Sze Min, Qiu, Xuan, Chong, Fui Teen, Li, Ke, Koh, Kelvin K.N., Tay, Gerald C.A., Skanthakumar, Thakshayeni, Hwang, Jacqueline S.G., Hon Lim, Tony Kiat, Ang, Mei Kim, Tan, Daniel S.W., Tan, Ngian-Chye, Tan, Hiang Khoon, Soo, Khee Chee, Iyer, N. Gopalakrishna
Publicado 2017

Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex

por van Rees, Dieke J, Bouti, Panagiota, Klein, Bart, Verkuijlen, Paul J H, van Houdt, Michel, Schornagel, Karin, Tool, Anton T J, Venet, David, Sotiriou, Christos, El-Abed, Sarra, Izquierdo, Miguel, Guillaume, Sébastien, Saura, Cristina, Di Cosimo, Serena, Huober, Jens, Roylance, Rebecca, Kim, Sung-Bae, Kuijpers, Taco W, van Bruggen, Robin, K van den Berg, Timo, Matlung, Hanke L
Publicado 2022

PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial

por Chia, Stephen K. L., Martin, Miguel, Holmes, Frankie A., Ejlertsen, Bent, Delaloge, Suzette, Moy, Beverly, Iwata, Hiroji, von Minckwitz, Gunter, Mansi, Janine, Barrios, Carlos H., Gnant, Michael, Tomašević, Zorica, Denduluri, Neelima, Šeparović, Robert, Kim, Sung-Bae, Jakobsen, Erik Hugger, Harvey, Vernon, Robert, Nicholas, Smith, John, Harker, Graydon, Zhang, Bo, Eli, Lisa D., Ye, Yining, Lalani, Alshad S., Buyse, Marc, Chan, Arlene
Publicado 2019

Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination

por Sharma, Ved P., Tang, Binwu, Wang, Yarong, Duran, Camille L., Karagiannis, George S., Xue, Emily A., Entenberg, David, Borriello, Lucia, Coste, Anouchka, Eddy, Robert J., Kim, Gina, Ye, Xianjun, Jones, Joan G., Grunblatt, Eli, Agi, Nathan, Roy, Sweta, Bandyopadhyaya, Gargi, Adler, Esther, Surve, Chinmay R., Esposito, Dominic, Goswami, Sumanta, Segall, Jeffrey E., Guo, Wenjun, Condeelis, John S., Wakefield, Lalage M., Oktay, Maja H.
Publicado 2021

Prevalence of Germline Pathogenic Variants in Cancer Predisposing Genes in Czech and Belgian Pancreatic Cancer Patients

por Wieme, Greet, Kral, Jan, Rosseel, Toon, Zemankova, Petra, Parton, Bram, Vocka, Michal, Van Heetvelde, Mattias, Kleiblova, Petra, Blaumeiser, Bettina, Soukupova, Jana, van den Ende, Jenneke, Nehasil, Petr, Tejpar, Sabine, Borecka, Marianna, Gómez García, Encarna B., Blok, Marinus J., Safarikova, Marketa, Kalousova, Marta, Geboes, Karen, De Putter, Robin, Poppe, Bruce, De Leeneer, Kim, Kleibl, Zdenek, Janatova, Marketa, Claes, Kathleen B. M.
Publicado 2021

Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells

por Koenders, Sebastiaan T. A., Wijaya, Lukas S., Erkelens, Martje N., Bakker, Alexander T., van der Noord, Vera E., van Rooden, Eva J., Burggraaff, Lindsey, Putter, Pasquale C., Botter, Else, Wals, Kim, van den Elst, Hans, den Dulk, Hans, Florea, Bogdan I., van de Water, Bob, van Westen, Gerard J. P., Mebius, Reina E., Overkleeft, Herman S., Le Dévédec, Sylvia E., van der Stelt, Mario
Publicado 2019

Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program

por Bychkovsky, Brittany L., Li, Tianyu, Sotelo, Jilliane, Tayob, Nabihah, Mercado, Joanna, Gomy, Israel, Chittenden, Anu, Kane, Sarah, Stokes, Samantha, Hughes, Melissa E., Kim, Ji Seok, Umeton, Renato, Awad, Mark M., Konstantinopoulos, Panagiotis A., Yurgelun, Matthew B., Wolpin, Brian M., Taplin, Mary-Ellen, Newmark, Randall E., Johnson, Bruce E., Lindeman, Neal I., MacConaill, Laura E., Garber, Judy E., Lin, Nancy U.
Publicado 2022

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

por Li, Chia-Wei, Lim, Seung-Oe, Xia, Weiya, Lee, Heng-Huan, Chan, Li-Chuan, Kuo, Chu-Wei, Khoo, Kay-Hooi, Chang, Shih-Shin, Cha, Jong-Ho, Kim, Taewan, Hsu, Jennifer L., Wu, Yun, Hsu, Jung-Mao, Yamaguchi, Hirohito, Ding, Qingqing, Wang, Yan, Yao, Jun, Lee, Cheng-Chung, Wu, Hsing-Ju, Sahin, Aysegul A., Allison, James P., Yu, Dihua, Hortobagyi, Gabriel N., Hung, Mien-Chie
Publicado 2016

Microfluidics-free single-cell genomics with templated emulsification

por Clark, Iain C., Fontanez, Kristina M., Meltzer, Robert H., Xue, Yi, Hayford, Corey, May-Zhang, Aaron, D’Amato, Chris, Osman, Ahmad, Zhang, Jesse Q., Hettige, Pabodha, Ishibashi, Jacob S. A., Delley, Cyrille L., Weisgerber, Daniel W., Replogle, Joseph M., Jost, Marco, Phong, Kiet T., Kennedy, Vanessa E., Peretz, Cheryl A. C., Kim, Esther A., Song, Siyou, Karlon, William, Weissman, Jonathan S., Smith, Catherine C., Gartner, Zev J., Abate, Adam R.
Publicado 2023

Effects of a time out consultation with the general practitioner on cancer treatment decision‐making: a randomised controlled trial: Time out with the general practitioner and canc...

por Perfors, Ietje A.A., Noteboom, Eveline A., de Wit, Niek J., van der Wall, Elsken, Visserman, Ella A., van Dalen, Thijs, Verhagen, Marc A.M.T., Witkamp, Arjen J., Koelemij, Ron, Flinterman, Annebeth E., van Dorst, Eleonora B.L., Pruissen‐Peeters, Kim A.B.M., Moons, Leon M.G., Schramel, Franz M.N.H., van Rens, Marcel T.M., Ernst, Miranda F., May, Anne M., Helsper, Charles W.
Publicado 2020

Prospects for Diffractive and Forward Physics at the LHC

por Albrow, M, Antchev, G, Arneodo, M, Avati, V, Bartalini, P, Berardi, V, Bottigli, U, Bozzo, M, Brucken, E, Burtovoy, V, Buzzo, A, Calicchio, M, Capurro, F, Catanesi, M G, Catastini, P, Ciocci, M A, Croft, R, Datsko, K, Deile, M, De Favereau De Jeneret, J, De Jesus Damiao, D, Robutti, E, de Roeck, A, D'Enterria, D G, De Wolf, E A, Eggert, K, Engel, R, Erhan, S, Ferro, F, García-Fuertes, W, Geist, W, Grothe, M, Guillaud, J P, Heino, J, Hees, A, Hilden, T, Kalliopuska, J, Kaspar, J, Katsas, P, Kim, V, Klyukhin, V, Kundrát, V, Kurvinen, K, Kuznetsov, A, Lami, S, Lamsa, J, Latino, G, Lauhakanga, R, Lippmaa, E, Lippmaa, J, Liu, Y, Loginov, A, Lokajícek, M, Lo Vetere, M, Lucas Rodriguez, F, Macri, M, Mäki, T, Meucci, M, Minutoli, S, Mnich, J, Moussienko, I, Murray, M, Niewiadomski, H, Noschis, E, Notarnicola, G, Ochesanu, S, Österberg, K, Oliveri, E, Oljemark, F, Orava, R, Oriunno, M, Ottela, M, Ovyn, S, Palazzi, P, Panagiotou, A D, Paoletti, R, Popov, V, Petrov, V, Pierzchala, T, Piotrzkowski, K, Radermacher, E, Radicioni, E, Rella, G, Reucroft, S, Ropelewski, Leszek, Rouby, X, Ruggiero, G, Rummel, A, Ruspa, M, Ryutin, R, Saarikko, H, Sanguinetti, G, Santoro, A F S, Santroni, A, Sarkisyan-Grinbaum, E, Sarycheva, L, Schilling, F P, Schlein, P E, Scribano Memoria, A, Sette, G, Snoeys, W, Snow, G R, Sobol, A, Solano, A, Spinella, F, Squillacioti, P, Swain, J, Sznajder, A, Tasevsky, M, Taylor, C C, Torp, F, Trummal, A, Turini, N, Van Der Donckt, M, Van Mechelen, P, Van Remortel, N, Vilela-Pereira, A, Whitmore, J, Zaborov, D
Publicado 2006

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

por Hartwig, Fernando Pires, Davies, Neil Martin, Horta, Bernardo Lessa, Ahluwalia, Tarunveer S, Bisgaard, Hans, Bønnelykke, Klaus, Caspi, Avshalom, Moffitt, Terrie E, Poulton, Richie, Sajjad, Ayesha, Tiemeier, Henning W, Dalmau-Bueno, Albert, Guxens, Mònica, Bustamante, Mariona, Santa-Marina, Loreto, Parker, Nadine, Paus, Tomáš, Pausova, Zdenka, Lauritzen, Lotte, Schnurr, Theresia M, Michaelsen, Kim F, Hansen, Torben, Oddy, Wendy, Pennell, Craig E, Warrington, Nicole M, Davey Smith, George, Victora, Cesar Gomes
Publicado 2019

FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response

por Velalopoulou, Anastasia, Karagounis, Ilias V., Cramer, Gwendolyn M., Kim, Michele M., Skoufos, Giorgos, Goia, Denisa, Hagan, Sarah, Verginadis, Ioannis I., Shoniyozov, Khayrullo, Chiango, June, Cerullo, Michelle, Varner, Kelley, Yao, Lutian, Qin, Ling, Hatzigeorgiou, Artemis G., Minn, Andy J., Putt, Mary, Lanza, Matthew, Assenmacher, Charles-Antoine, Radaelli, Enrico, Huck, Jennifer, Diffenderfer, Eric, Dong, Lei, Metz, James, Koumenis, Constantinos, Cengel, Keith A., Maity, Amit, Busch, Theresa M.
Publicado 2021

Kidney failure related to broad-spectrum antibiotics in critically ill patients: secondary end point results from a 1200 patient randomised trial

por Jensen, Jens-Ulrik Stæhr, Hein, Lars, Lundgren, Bettina, Bestle, Morten Heiberg, Mohr, Thomas, Andersen, Mads Holmen, Thornberg, Klaus Julius, Løken, Jesper, Steensen, Morten, Fox, Zoë, Tousi, Hamid, Søe-Jensen, Peter, Lauritsen, Anne Øberg, Strange, Ditte Gry, Reiter, Nanna, Thormar, Katrin, Fjeldborg, Paul Christian, Larsen, Kim Michael, Drenck, Niels-Erik, Johansen, Maria Egede, Nielsen, Lene Ryom, Østergaard, Christian, Kjær, Jesper, Grarup, Jesper, Lundgren, Jens D
Publicado 2012