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121“…METHODS: Genetic instruments for nine sex steroid hormones and sex hormone-binding globulin (SHBG) were obtained from genome-wide association studies (GWAS) of UK Biobank (total testosterone (TT) N: 230,454, bioavailable testosterone (BT) N: 188,507 and SHBG N: 189,473), The United Kingdom Household Longitudinal Study (DHEAS N: 9722), the LIFE-Adult and LIFE-Heart cohorts (estradiol N: 2607, androstenedione N: 711, aldosterone N: 685, progesterone N: 1259 and 17-hydroxyprogesterone N: 711) and the CORtisol NETwork (CORNET) consortium (cortisol N: 25,314). …”
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122por Clark, Bradley C., Sanchez‐de‐Toledo, Joan, Bautista‐Rodriguez, Carles, Choueiter, Nadine, Lara, Diego, Kang, Hechaan, Mohsin, Shazia, Fraisse, Alain, Cesar, Sergi, Sattar Shaikh, Abdul, Escobar‐Diaz, Maria C., Hsu, Daphne T., Randanne, Paula C., Aslam, Nadeem, Kleinmahon, Jake, Lamour, Jacqueline M, Johnson, Jonathan N., Sarquella‐Brugada, Georgia, Chowdhury, Devyani“…Our objective is to describe the cardiac manifestations found in an international cohort of 55 pediatric cases with multi‐system inflammatory syndrome (MIS‐C) during the SARS‐CoV2 pandemic. METHODS AND RESULTS: We reviewed data on previously healthy pediatric patients (≤18 years) with structurally normal hearts who presented at hospitals in the United States, United Kingdom, Spain and Pakistan with MIS‐C and had consultation with a pediatric cardiologist. …”
Publicado 2020
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123por Kim, Sung-Tae, Kim, Byung-Joon, Lim, Dong-Mee, Song, In-Geol, Jung, Jang-Han, Lee, Kang-Woo, Park, Keun-Young, Cho, Youn-Zoo, Lee, Dae-Ho, Koh, Gwan-Pyo“…The present study was designed to examine whether the basal C-peptide levels correlate with cardiovascular risk in type 2 diabetes mellitus (T2DM) patients. METHODS: Data was obtained from 467 patients with T2DM from two institutions who were followed for four years. …”
Publicado 2011
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124por Barletta, William A“…The first variants of concern (VoCs), Alpha (B1.1.7) and Gamma (P.1), first appeared in the United Kingdom and Brazil, respectively. The Delta (B.1.617.2) variant, seen in India in October 2020, dominated COVID-19 infections across all regions through the second half of 2021. …”
Publicado 2022
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125por Al-Mutairi, Abrar M., Alshabeeb, Mohammad A., Abohelaika, Salah, Alomar, Fadhel A., Bidasee, Keshore R.“…BACKGROUND: The lockdown at the start of coronavirus disease 2019 (COVID-19) pandemic in Saudi Arabia (March 2020 to June 2020) shifted routine in-person care for patients with type 2 diabetes mellitus (T2DM) to telemedicine. The aim of this study was to investigate the impact telemedicine had during this period on glycemic control (HbA1c) in patients with T2DM METHODS: 4,266 patients with T2DM were screened from five Ministry of National Guard Health Affairs hospitals in the Kingdom of Saudi Arabia. …”
Publicado 2023
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126“…Conclusions QRISK2 is more accurate in identifying a high risk population for cardiovascular disease in the United Kingdom than the NICE version of the Framingham equation. …”
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127por Emdin, Connor A, Anderson, Simon G, Callender, Thomas, Conrad, Nathalie, Salimi-Khorshidi, Gholamreza, Mohseni, Hamid, Woodward, Mark, Rahimi, Kazem“…Peripheral arterial disease was associated with an increased risk of 11 different vascular events, including ischaemic heart disease (1.68, 1.58 to 1.79), heart failure (1.63, 1.52 to 1.75), aortic aneurysm (2.10, 1.79 to 2.45), and chronic kidney disease (1.31, 1.25 to 1.38), but not haemorrhagic stroke. …”
Publicado 2015
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128por Ogedengbe, O Stephen, Ezeani, Ignatius U, Chukwuonye, Ijezie I, Anyabolu, Ernest N, Ozor, Ikemefuna I, Eregie, Aihanuwa“…BACKGROUND: The aim of this study is to evaluate the impact of coexistence of metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM) on the estimated cardiovascular risk as calculated using the United Kingdom Prospective Diabetic Study risk engine (UKPDS-RE) and also to determine the impact of the coexistence of MS and T2DM on the 10-year risk of developing coronary heart disease and stroke. …”
Publicado 2015
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129por Filion, Kristian B, Lix, Lisa M, Yu, Oriana HY, Dell’Aniello, Sophie, Douros, Antonios, Shah, Baiju R, St-Jean, Audray, Fisher, Anat, Tremblay, Eric, Bugden, Shawn C, Alessi-Severini, Silvia, Ronksley, Paul E, Hu, Nianping, Dormuth, Colin R, Ernst, Pierre, Suissa, Samy, Suissa, Samy, Dormuth, Colin R, Hemmelgarn, Brenda R, Quail, Jacqueline, Chateau, Dan, Paterson, J Michael, LeLorier, Jacques, Levy, Adrian R, Ernst,, Pierre, Filion, Kristian B, Lix, Lisa M, Platt,, Robert W, Sketris, Ingrid S“…SETTING: Canadian Network for Observational Drug Effect Studies (CNODES), with administrative healthcare databases from seven Canadian provinces and the United Kingdom, 2013-18. POPULATION: 209 867 new users of a SGLT2 inhibitor matched to 209 867 users of a DPP-4 inhibitor on time conditional propensity score and followed for a mean of 0.9 years. …”
Publicado 2020
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130por Abdel-Razaq, Wesam, Alzahrani, Mohammed, Al Yami, Majed, Almugibl, Faisal, Almotham, Mohammed, Alregaibah, Razan“…RESULTS: A total of 146 patients were included in the study with an average age of 52.7 (standard deviation = 12.2) years. Thirty-two (21.9%) patients developed cardiotoxicity. …”
Publicado 2019
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131por STEFAN, RAMONA MARIA, NITA, CRISTINA, CRACIUN, ANCA, RUSU, ADRIANA, HANCU, NICOLAE“…The cardiovascular diseases risk factors were calculated using the United Kingdom Prospective Diabetes Study Risk Engine. RESULTS: The mean age at diagnosis was 53.61±10.66 years. …”
Publicado 2015
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132por Kansal, A., Reifsnider, O. S., Proskorovsky, I., Zheng, Y., Pfarr, E., George, J. T., Kandaswamy, P., Ruffolo, A.“…Model performance was assessed by comparing predicted and observed outcomes at 3 years. Costs in the United Kingdom (UK) and health utilities were obtained from published literature. …”
Publicado 2019
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133por Mansfield, Carol, Botha, Willings, Vondeling, Gerard T., Klein, Kathleen, Wang, Kongming, Singh, Jasmeet, Hackshaw, Michelle D.“…Avoiding a 15% risk of heart failure had the largest MAB (5.8 additional months of PFS), followed by avoiding a 15% risk of serious lung damage and infections (4.6 months), possible severe liver function problems (4.2 months), severe nausea/vomiting (3.7 months), and severe diarrhea (2.3 months) compared with having none of the AEs. …”
Publicado 2022
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134por Weerarathna, Thilak, Liyanage, Gayani, Herath, Meththananda, Weerarathna, Miyuru, Amarasinghe, Isuru“…Those with urine albumin excretion over 30 mg/g creatinine were considered as having albuminuria, and eGFR was calculated using modified diet in renal disease (MDRD) formula. Ten-year coronary heart disease risk (CHDR) in all patients was calculated using United Kingdom Prospective Diabetes Study risk engine, and those with CHDR > 10% were considered as having high risk. …”
Publicado 2018
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135por Liu, Qiaolu, Qiu, Jianfeng, Sun, Shuxin, Wang, Xiaoqiang, Sun, Zhanguo, Zhao, Huihui“…BACKGROUND: There are few data on the clinical significance of coronary computed tomography angiography (CCTA) in asymptomatic type 2 diabetes mellitus (T2DM) patients. We performed a retrospective study to evaluate coronary heart disease (CHD) screening in asymptomatic patients with T2DM using CCTA and CHD risk stratification prediction. …”
Publicado 2022
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136por Perera, Divaka, Morgan, Holly P., Ryan, Matthew, Dodd, Matthew, Clayton, Tim, O’Kane, Peter D., Greenwood, John P., Walsh, Simon J., Weerackody, Roshan, McDiarmid, Adam, Amin-Youssef, George, Strange, Julian, Modi, Bhavik, Lockie, Timothy, Hogrefe, Kai, Ahmed, Fozia Z., Behan, Miles, Jenkins, Nicholas, Abdelaal, Eltigani, Anderson, Michelle, Watkins, Stuart, Evans, Richard, Rinaldi, Christopher A., Petrie, Mark C.Enlace del recurso
Publicado 2023
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137por Perera, Divaka, Ryan, Matthew, Morgan, Holly P., Greenwood, John P., Petrie, Mark C., Dodd, Matthew, Weerackody, Roshan, O’Kane, Peter D., Masci, Pier Giorgio, Nazir, Muhummad Sohaib, Papachristidis, Alexandros, Chahal, Navtej, Khattar, Rajdeep, Ezad, Saad M., Kapetanakis, Stam, Dixon, Lana J., De Silva, Kalpa, McDiarmid, Adam K., Marber, Michael S., McDonagh, Theresa, McCann, Gerry P., Clayton, Tim C., Senior, Roxy, Chiribiri, Amedeo“…DESIGN, SETTING, AND PARTICIPANTS: Prospective open-label randomized clinical trial recruiting between August 28, 2013, and March 19, 2020, with a median follow-up of 3.4 years (IQR, 2.3-5.0 years). A total of 40 secondary and tertiary care centers in the United Kingdom were included. …”
Publicado 2023
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138por Reynoso-Noverón, Nancy, Mehta, Roopa, Almeda-Valdes, Paloma, Rojas-Martinez, Rosalba, Villalpando, Salvador, Hernández-Ávila, Mauricio, Aguilar-Salinas, Carlos A“…BACKGROUND: To estimate the incidence of complications, life expectancy and diabetes related mortality in the Mexican diabetic population over the next two decades using data from a nation-wide, population based survey and the United Kingdom Prospective Diabetes Study (UKPDS) outcome model METHODS: The cohort included all patients with type 2 diabetes evaluated during the National Health and Nutrition Survey (ENSANut) 2006. …”
Publicado 2011
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139por Seon, Choon Sik, Min, Kyung Wan, Lee, Seung Yup, Nho, Kyoung Woo, Park, Se Hwan, Koo, Bo Kyung, Han, Kyung Ah“…Few studies have evaluated the cardiovascular disease (CVD) risk simultaneously using the United Kingdom Prospective Diabetes Study (UKPDS) risk engine and non-invasive vascular tests in patients with newly diagnosed type 2 diabetes. …”
Publicado 2011
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140por Wilshaw, Jenny, Rosenthal, Steven L., Wess, Gerhard, Dickson, Dave, Bevilacqua, Luca, Dutton, Emily, Deinert, Michael, Abrantes, Ricardo, Schneider, Ingo, Oyama, Mark A., Gordon, Sonya G., Elliott, Jonathan, Xia, Dong, Boswood, Adrian“…OBJECTIVES: To evaluate whether cardiac biomarker concentrations can be used alongside other clinical data to identify stage B2 dogs. ANIMALS: Client‐owned dogs (n = 1887) with preclinical DMVD prospectively sampled in Germany, the United Kingdom, and the United States. …”
Publicado 2021
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