The Anticancer Ruthenium Compound BOLD-100 Targets Glycolysis and Generates a Metabolic Vulnerability towards Glucose Deprivation

por Baier, Dina, Schoenhacker-Alte, Beatrix, Rusz, Mate, Pirker, Christine, Mohr, Thomas, Mendrina, Theresa, Kirchhofer, Dominik, Meier-Menches, Samuel M., Hohenwallner, Katharina, Schaier, Martin, Rampler, Evelyn, Koellensperger, Gunda, Heffeter, Petra, Keppler, Bernhard, Berger, Walter
Publicado 2022

p53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on PARylation-Mediated Cell Death Induction

por Dinhof, Carina, Pirker, Christine, Kroiss, Philipp, Kirchhofer, Dominik, Gabler, Lisa, Gojo, Johannes, Lötsch-Gojo, Daniela, Stojanovic, Mirjana, Timelthaler, Gerald, Ferk, Franziska, Knasmüller, Siegfried, Reisecker, Johannes, Spiegl-Kreinecker, Sabine, Birner, Peter, Preusser, Matthias, Berger, Walter
Publicado 2020

The impact of heat waves on mortality in 9 European cities: results from the EuroHEAT project

por D'Ippoliti, Daniela, Michelozzi, Paola, Marino, Claudia, de'Donato, Francesca, Menne, Bettina, Katsouyanni, Klea, Kirchmayer, Ursula, Analitis, Antonis, Medina-Ramón, Mercedes, Paldy, Anna, Atkinson, Richard, Kovats, Sari, Bisanti, Luigi, Schneider, Alexandra, Lefranc, Agnès, Iñiguez, Carmen, Perucci, Carlo A
Publicado 2010

Surveillance of Summer Mortality and Preparedness to Reduce the Health Impact of Heat Waves in Italy

por Michelozzi, Paola, de’ Donato, Francesca K., Bargagli, Anna Maria, D’Ippoliti, Daniela, De Sario, Manuela, Marino, Claudia, Schifano, Patrizia, Cappai, Giovanna, Leone, Michela, Kirchmayer, Ursula, Ventura, Martina, di Gennaro, Marta, Leonardi, Marco, Oleari, Fabrizio, De Martino, Annamaria, Perucci, Carlo A.
Publicado 2010

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

por de Bruin, Alain, A. Cornelissen, Peter W., Kirchmaier, Bettina C., Mokry, Michal, Iich, Elhadi, Nirmala, Ella, Liang, Kuo-Hsuan, D. Végh, Anna M., Scholman, Koen T., Groot Koerkamp, Marian J., Holstege, Frank C., Cuppen, Edwin, Schulte-Merker, Stefan, Bakker, Walbert J.
Publicado 2016

Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge

por Maun, Henry R., Vij, Rajesh, Walters, Benjamin T., Morando, Ashley, Jackman, Janet K., Wu, Ping, Estevez, Alberto, Chen, Xiaocheng, Franke, Yvonne, Lipari, Michael T., Dennis, Mark S., Kirchhofer, Daniel, Ciferri, Claudio, Loyet, Kelly M., Yi, Tangsheng, Eigenbrot, Charles, Lazarus, Robert A., Koerber, James T.
Publicado 2020

Association of Influenza Vaccination and Prognosis in Patients Testing Positive to SARS-COV-2 Swab Test: A Large-Scale Italian Multi-Database Cohort Study

por Massari, Marco, Spila-Alegiani, Stefania, Fabiani, Massimo, Belleudi, Valeria, Trifirò, Gianluca, Kirchmayer, Ursula, Poggi, Francesca Romana, Mancuso, Pamela, Menniti-Ippolito, Francesca, Gini, Rosa, Bartolini, Claudia, Leoni, Olivia, Ercolanoni, Michele, Da-Re, Filippo, Guzzinati, Stefano, Luxi, Nicoletta, Riccardo, Flavia, Giorgi-Rossi, Paolo
Publicado 2021

Plasma Metabolomics Reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of the Transcription Factor 7-Like 2 Polymorphism rs7903146

por Then, Cornelia, Wahl, Simone, Kirchhofer, Anna, Grallert, Harald, Krug, Susanne, Kastenmüller, Gabi, Römisch-Margl, Werner, Claussnitzer, Melina, Illig, Thomas, Heier, Margit, Meisinger, Christa, Adamski, Jerzy, Thorand, Barbara, Huth, Cornelia, Peters, Annette, Prehn, Cornelia, Heukamp, Ina, Laumen, Helmut, Lechner, Andreas, Hauner, Hans, Seissler, Jochen
Publicado 2013

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes

por Hewings, David S., Heideker, Johanna, Ma, Taylur P., AhYoung, Andrew P., El Oualid, Farid, Amore, Alessia, Costakes, Gregory T., Kirchhofer, Daniel, Brasher, Bradley, Pillow, Thomas, Popovych, Nataliya, Maurer, Till, Schwerdtfeger, Carsten, Forrest, William F., Yu, Kebing, Flygare, John, Bogyo, Matthew, Wertz, Ingrid E.
Publicado 2018

HGG-50. Specific sensitivity of pediatric high-grade glioma with ATRX inactivation to PARP inhibitor combinations

por Laemmerer, Anna, Kirchhofer, Dominik, Madlener, Sibylle, Loetsch-Gojo, Daniela, Jaunecker, Carola N, Gabler, Lisa, Mayr, Lisa, Stepien, Natalia, Baumgartner, Alicia, Dieckmann, Karin, Pfister, Stefan M, Kool, Marcel, Krausert, Sonja, Gopisetty, Apurva, Jäger, Natalie, Peyrl, Andreas, Azizi, Amedeo A, Berger, Walter, Gojo, Johannes
Publicado 2022

TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF(V600E)/TERT promoter double-mutated glioma

por Gabler, Lisa, Lötsch, Daniela, Kirchhofer, Dominik, van Schoonhoven, Sushilla, Schmidt, Hannah M., Mayr, Lisa, Pirker, Christine, Neumayer, Katharina, Dinhof, Carina, Kastler, Lucia, Azizi, Amedeo A., Dorfer, Christian, Czech, Thomas, Haberler, Christine, Peyrl, Andreas, Kumar, Rajiv, Slavc, Irene, Spiegl-Kreinecker, Sabine, Gojo, Johannes, Berger, Walter
Publicado 2019

ETMR-12. Novel cell models of CNS tumors with BCOR fusion or internal tandem duplication suggest FGFR and PDGFR as promising therapy targets

por Kirchhofer, Dominik, Lötsch-Gojo, Daniela, Gabler, Lisa, Jaunecker, Carola N, Piontek, Martin, Mayr, Lisa, Englinger, Bernhard, Pirker, Christine, Mohr, Thomas, Lämmerer, Anna, Schmitt-Hoffner, Felix, Boidol, Bernd, Kubiceck, Stefan, Peyrl, Andreas, Azizi, Amadeo A, Dorfer, Christian, Haberler, Christine, Kool, Marcel, Berger, Walter, Gojo, Johannes
Publicado 2022

EPEN-23. Interaction of epigenetic regulation and telomerase re-activation in high-risk ependymoma

por Jaunecker, Carola N, Kirchhofer, Dominik, Madlener, Sibylle, Laemmerer, Anna, Gabler, Lisa, Pirker, Christine, Piontek, Martin, Maaß, Kendra, Okonechnikov, Konstanitin, Englinger, Bernhard, Jiang, Li, Mayr, Lisa, Senfter, Daniel, Spiegl-Kreinecker, Sabine, Stepien, Natalia, Dorfer, Christian, Filbin, Mariella, Kool, Marcel, Gojo, Johannes, Berger, Walter, Loetsch-Gojo, Daniela
Publicado 2022

Methodology of the brodalumab assessment of hazards: a multicentre observational safety (BRAHMS) study

por Reilev, Mette, Jensen, Peter Bjødstrup, Ranch, Lise Skov, Egeberg, Alexander, Furu, Kari, Gembert, Karin, Hagg, David, Haug, Ulrike, Karlstad, Øystein, Reutfors, Johan, Schäfer, Wiebke, Schwartz, Sarina, Smits, Elisabeth, Holthius, Emily, Herings, Ron, Trifirò, Gianluca, Kirchmayer, Ursula, Rosa, Alessandro Cesare, Belleudi, Valeria, Gini, Rosa, Støvring, Henrik, Hallas, Jesper
Publicado 2023

Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry

por Kalaba, Predrag, Pacher, Katharina, Neill, Philip John, Dragacevic, Vladimir, Zehl, Martin, Wackerlig, Judith, Kirchhofer, Michael, Sartori, Simone B., Gstach, Hubert, Kouhnavardi, Shima, Fabisikova, Anna, Pillwein, Matthias, Monje-Quiroga, Francisco, Ebner, Karl, Prado-Roller, Alexander, Singewald, Nicolas, Urban, Ernst, Langer, Thierry, Pifl, Christian, Lubec, Jana, Leban, Johann Jakob, Lubec, Gert
Publicado 2023

Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy

por Tom, Irene, Pham, Victoria C., Katschke, Kenneth J., Li, Wei, Liang, Wei-Ching, Gutierrez, Johnny, Ah Young, Andrew, Figueroa, Isabel, Eshghi, Shadi Toghi, Lee, ChingWei V., Kanodia, Jitendra, Snipas, Scott J., Salvesen, Guy S., Lai, Phillip, Honigberg, Lee, van Lookeren Campagne, Menno, Kirchhofer, Daniel, Baruch, Amos, Lill, Jennie R.
Publicado 2020

Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs

por Herring, Shawn, Oda, Jessica M., Wagoner, Jessica, Kirchmeier, Delaney, O’Connor, Aidan, Nelson, Elizabeth A., Huang, Qinfeng, Liang, Yuying, DeWald, Lisa Evans, Johansen, Lisa M., Glass, Pamela J., Olinger, Gene G., Ianevski, Aleksandr, Aittokallio, Tero, Paine, Mary F., Fink, Susan L., White, Judith M., Polyak, Stephen J.
Publicado 2021

Novel Insights into Diagnosis, Biology, and Treatment of Primary Diffuse Leptomeningeal Melanomatosis

por Baumgartner, Alicia, Stepien, Natalia, Mayr, Lisa, Madlener, Sibylle, Dorfer, Christian, Schmook, Maria T., Traub-Weidinger, Tatjana, Lötsch-Gojo, Daniela, Kirchhofer, Dominik, Reisinger, Dominik, Hedrich, Cora, Arshad, Saleha, Irschik, Stefan, Boztug, Heidrun, Engstler, Gernot, Bernkopf, Marie, Rifatbegovic, Fikret, Höller, Christoph, Slavc, Irene, Berger, Walter, Müllauer, Leonhard, Haberler, Christine, Azizi, Amedeo A., Peyrl, Andreas, Gojo, Johannes
Publicado 2021

A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions

por Kouhnavardi, Shima, Ecevitoglu, Alev, Dragačević, Vladimir, Sanna, Fabrizio, Arias-Sandoval, Edgar, Kalaba, Predrag, Kirchhofer, Michael, Lubec, Jana, Niello, Marco, Holy, Marion, Zehl, Martin, Pillwein, Matthias, Wackerlig, Judith, Murau, Rita, Mohrmann, Andrea, Beard, Kathryn R., Sitte, Harald H., Urban, Ernst, Sagheddu, Claudia, Pistis, Marco, Plasenzotti, Roberto, Salamone, John D., Langer, Thierry, Lubec, Gert, Monje, Francisco J.
Publicado 2022

Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage

por AhYoung, Andrew P., Eckard, Sterling C., Gogineni, Alvin, Xi, Hongkang, Lin, S. Jack, Gerhardy, Stefan, Cox, Christian, Phung, Qui T., Hackney, Jason A., Katakam, Anand Kumar, Reichelt, Mike, Caplazi, Patrick, Manzanillo, Paolo, Zhang, Juan, Roose-Girma, Merone, Tam, Lucinda W., Newman, Robert J., Murthy, Aditya, Weimer, Robby M., Lill, Jennie R., Lee, Wyne P., Grimbaldeston, Michele, Kirchhofer, Daniel, Campagne, Menno van Lookeren
Publicado 2020